Bernie Endyarni Medise
Departemen Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Indonesia Rumah Sakit Dr. Cipto Mangunkusumo, Jakarta

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Journal : Amerta Nutrition

Growth and Development in Preterm Infants: What is The Long-Term Risk? Bernie Endyarni Medise
Amerta Nutrition Vol. 5 No. 1SP (2021): AMERTA NUTRITION SUPPLEMENTARY EDITION
Publisher : Universitas Airlangga, Kampus C, Mulyorejo, Surabaya-60115, East Java, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v5i1SP.2021.27-33

Abstract

ABSTRACT Background: Indonesia comes in the fifth for the greatest number of preterm births. Preterm infants may inflict various complication as the result of underdeveloped immunity, affecting their growth and development in the long run until they reach adult phase. Such complications could be prevented through adequate nutrition fulfillment. Purpose: This article aimed to elaborate the characteristics of growth and development of premature babies, long term effect on the development and the impact of immunity and gut health of preterm infants in supporting their growth and development. Methods: References cited in this article were obtained from the latest primary literature within the last 10 years. Discussion: The rate and ability of infants to perform catch-up growth depends on the birth weight and gestation age, at which the lower birth weight and lower gestational age had slower rate. Brain structures that of preterm infants differ compared to the term, and these changes give rise to various clinical outcomes, including long term emotional, behavioral changes, cognitive and executive functioning. Immature immune system in preterm infants reduces the protective ability by innate and adaptive immunity in overcoming pathogens compared to term infants, including gut microbiota prematurity which affects nutrition absorption and growth and development catch up ability. Appropriate and adequate nutrition supplementation has shown beneficial effects in promoting the growth of normal gut flora, which allow better absorption of nutrition and therefore enhancing growth rate and supporting the development of preterm infants. Conclusions: Optimal growth and development of preterm infants are supported by sufficient nutrition supplementation to support the growth of gut microbiota, facilitating the catch-up growth and development of premature infants and immune system maturity.
Co-Authors Ali Alhadar Aman Bhakti Pulungan, Aman Bhakti Antonius H Pudjiadi, Antonius H Arief, Wresty Badriul Hegar Syarif Benedictus Bermanshah, Evita Karianni Budi Wiweko Corrie Wawolumaja Dania Mirza Ramadhanty Dave Anderson Dewi Anggraeni Dewi Friska Dharma Asih, Ni Ketut Susila Diana Sunardi Elina Waiman Erfi Prafiantini Erni Hernawati Purwaningsih, Erni Hernawati Ervira Wahyuni Erwin Hendrata Ganda Ilmana Gitayanti Gitayanti H.F. Wulandari Hanifah Oswari Hartono Gunardi Hartono Gunardi Hartono Gunardi Hartono Gunardi Hartono Gunardi Hikari Ambara Sjakti, Hikari Ambara I Boediman Ikhsan Johnson Ikhsan Johnson Intan Tumbelaka Irawan Mangunatmadja Irene Yuniar, Irene Ismi Citra Ismail, Ismi Citra Jessica Ferdi Jessica Ferdi Joedo Prihartono Jose RL Batubara Kartika Erida Brohet Kholisah Nasution Krishna Adi Wibisana Lee, Hee Jae Lenora Mohd. Ishak Lina Ninditya Liza Pratiwi M. Azharry Rully Sjahrullah M. Ramdhani Yassien Marie Christabelle Muhammad Faizi, Muhammad Muhammad Prasetio Wardoyo Muzal Kadim Naela Fadhila Nastiti Kaswandani Novie Amelia Chozie Nuri Purwito Adi Olfriani, Ciho Priscilla, Birgitta Priyono, Harim Pustika Amalia Wahidiyat Putri Maharani Tristanita Marsubrin Ray Wagiu Basrowi Ray Wagiu Basrowi Renno Hidayat Retnaningdyah, Windri Reza, Maulana Okta Rini Mulia Sari Rini Sekartini Rini Sekartini Rini Sekartini Rini Sekartini Rini Sekartini Rizki Yusrini Pohan Roro Rukmi Windi Perdani, Roro Rukmi Rosalina Dewi Roeslani Saptawati Bardosono Saptawati Bardosono Setyo Handryastuti Silva Audya Perdana Soebadi, Amanda Soedjatmiko Soedjatmiko Soedjatmiko Soedjatmiko Soedjatmiko Soedjatmiko Soesanti, Frida Sreshta Mukhi Sreshta Mukhi Sukamto Koesnoe Suzy Maria Thandavarayan, Rajarajan Amirthalingam Tirza Z. Tamin Titi Sularyo Titis Prawitasari, Titis Tjhin Wiguna Tjhin Wiguna Trevino Pakasi Tri Lestari H Wahyuni Indawati, Wahyuni Wahyuni, Luh Kurnia Wangke, Lydia Wardani, Amanda Saphira Wawaimuli Arozal Wirahmadi, Angga Yoga Devaera Yoga Devaera, Yoga Yogi Prawira Yulianti Wibowo Yulianti Wibowo Zakiudin Munasir Zakiudin Munasir Zizlavsky, Semiramis