Article Per Year (5 Year)
p-Index From 2021 - 2026
2.543
P-Index
This Author published in this journals
All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Health Information : Jurnal Penelitian Jurnal Pengabdian kepada Masyarakat Nusantara Journal of Experimental and Clinical Pharmacy (JECP) Pharmaceutical Reports Journal of Noncommunicable Diseases (JOND) Jurnal Katalisator JURNAL KESEHATAN YAMASI MAKASSAR Sahabat Sosial: Jurnal Pengabdian Masyarakat International Journal of Health Sciences Jurnal Sains dan Kesehatan Indonesian Journal of Jamu
Rahmah Mustarin
Pharmacy Study Program, Faculty Of Medicine And Health Sciences, University Of Muhammadiyah Makassar
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences

Published : 17 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 17 Documents
Search

 1   2 
ANTIBACTERIA ACTIVITY ETHANOL EXTRACT OF ACHRAS ZAPOTA L. FRUIT AND LAGENARIA SICERARIA (MOLINA) STANDL. AGAINST SALMONELLA TYPHI Saldi Hapiwaty; Yuri Pratiwi Utami; Imrawati; Mahfuzun Bone; Nurjannah Bachri; Rahmah Mustarin; Ainun Jariah; Zahira Amody; Benedikta Winne Angela
JURNAL KATALISATOR Vol. 9 No. 2 (2024): Jurnal Katalisator Volume 9 No.2, Oktober 2024
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v9i2.3103

Abstract

The Synergistic of antibacterial is an interaction of two antibacterial agents that produces a greater inhibitory effect on bacteria, compared to the individual antibacterial effects of the two agents. The purpose of this study was to determine the synergistic effect of anti-bacterial extract of sapodilla fruit (Achras zapota L.) and water gourd (Lagenaria siceraria (Molina) Standl.) extract against Salmonella typhi bacteria. Extraction of sapodilla fruit and water gourd fruit was carried out by maceration method using 96% ethanol (1:10). Determination of the value of the minimum inhibitory concentration (MIC) of anti-bacterial sapodilla manila fruit and water gourd fruit was carried out by the checkerboard assay method using a 96 wells microplate by calculating the Fractional Inhibition Concentration Index (FICI) value. The results showed that the single MIC value of sapodilla manila fruit and water gourd fruit respectively are 50 mg/mL and 100 mg/mL. The interaction between the two is expressed as a Fractional Inhibitory Concentration Index (FICI) with a value of 1.5. The FICI values ​​indicate different antibacterial effects of the combination of sapodilla fruit and water gourd fruit against Salmonella typhi. Keywords: Synergistic, Salmonella typhi, Achras zapota L., Lagenaria siceraria (Molina) Standl., FICI
Fraksi Daun Andong Merah (Cordyline fruticose (L.) A. Cheval) Berpotensi sebagai Sitotoksik Metode BSLT Utami, Yuri Pratiwi; Imrawati, Imrawati; Mus, Suwahyuni; Astri, Andi Astri Sri Nurul Fardila; Mustarin, Rahmah
JOURNAL OF NONCOMMUNICABLE DISEASES Vol 4, No 1 (2024): April 2024
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jond.v4i1.974

Abstract

Andong merah (Cordyline fruticosa (L.) A. Cheval) merupakan tanaman yang banyak digunakan sebagai obat tradisional. Kandungan senyawa yang ada pada tanaman andong merah berupa metabolit sekunder diantaranya polifenol, flavonoid, saponin, alkaloid, steroid dan triterpenoid sedangkan pada daun andong merah mengandung senyawa polifenol, tannin dan flavonoid. Tujuan dari penelitian ini yaitu untuk mengetahui sitotoksisitas fraksi daun andong merah (C. Fruticosa) terhadap larva udang Artemia salina Leach menggunakan metode BSLT. Ekstrak etanol 70% menghasilkan tiga fraksi yaitu fraksi n-heksan, fraksi etil asetat, dan fraksi etanol-air dengan teknik ekstraksi cair-cair (ECC) menggunakan tiga pelarut. Kemudian diuji sitotoksisitasnya dari seri konsentrasi 20 ppm, 40 ppm, 60 ppm, 80 ppm dan 100 ppm serta kontrol negatif. Hasil yang diperoleh dari penelitian ini berupa aktivitas sitotoksik fraksi dengan parameter nilai LC50 yaitu fraksi n-heksan 25,05 ppm ppm, fraksi etil aetat 85,21 ppm dan fraksi etanol-air 32,39 ppm. Kesimpulannya yakni fraksi dari daun andong merah (C. Fruticosa) termasuk dalam kategori sitotoksistas kuat. Cordyline fruticosa (L.) A. Cheval is a plant that is widely used as a traditional medicine. The compounds contained in the red oak plant are secondary metabolites including polyphenols, flavonoids, saponins, alkaloids, steroids and triterpenoids whereas in the leaves of the red andong contain compound polyphenol, tannins and flavanoids. The aim of the study was to determine the cytotoxicity of the C. fruticosa fraction to the larvae of the shrimp Artemia salina Leach using the BSLT method. The 70% ethanol extract produces three fractions namely the n-hexane fraction, the ethyl acetate fraction and the ethanole-water fraction using the liquid-liquid extraction technique (ECC) using three solvents. Then they tested their cytotoxicity from a series of concentrations of 20 ppm, 40 ppm and 60 ppm as well as negative controls. The results obtained from this study were fractional cytotoxic activity with LC50 parameters of 25.05 ppm n-hexane fraction, 85.21 ppm ethyl acetate fraction and 32.39 ppm ethanol-water fraction. The conclusion is that the fraction of the C. Fruticosa leaves belongs to the category of strong cytotoxists
Α-GLUCOSIDASE ENZYME INHIBITOR ACTIVITY OF ETLINGERA ELATIOR LEAF EXTRACT WITH SOLVENT VARIATION Imrawati Imrawati; Yuri Pratiwi Utami; Yuniar Dwi Yanti; Tuti Handayani; Nurzadrina wahyuddin; Zahira Amody; Aulia Debby Pelu; Rahmah Mustarin; Indri Indri
JURNAL KATALISATOR Vol. 10 No. 2 (2025): Jurnal Katalisator, Volume 10 No 2 Oktober 2025
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v10i2.3462

Abstract

Diabetes mellitus (DM) is a chronic metabolic disease characterized by hyperglycemia due to impaired insulin production or utilization. The increasing prevalence of diabetes, especially type 2, is a global concern due to the risk of complications it poses. One approach in treating type 2 diabetes is to inhibit the α-glucosidase enzyme to slow down glucose absorption. This research aims to identify the potential of patikala leaf extract as an α-glucosidase enzyme inhibitor. Using an experimental method with patikala leaf samples collected from Mariri Hamlet, Banyuurip Village, Bone-bone District, North Luwu Regency. Extraction was performed using the maceration method with variations in solvents: 70% ethanol, ethyl acetate, and n-hexane. The α-glucosidase enzyme inhibition activity was measured using a microplate reader and analyzed to determine the IC50 value. From the percentage inhibition data, the IC50 values obtained for 30% ethanol extract of patikala leaves were 351.95 µg/mL, for 70% ethanol extract of patikala leaves were 444.83 µg/mL, for 96% ethanol extract of patikala leaves were 362.27 µg/mL, for ethyl acetate extract of patikala leaves were 163.59 µg/mL, and for n-hexane extract of patikala leaves were 294.90 µg/mL, indicating that patikala leaf extracts with variations in solvent or extraction method exhibited very weak α-glucosidase enzyme inhibition activity. In conclusion, based on the research results obtained, the extract with variations in the solvent or extractant. Patikala leaf extract has an inhibitory activity against the α-glucosidase enzyme, which is categorized as very weak because it has an IC50 value > 100 µg/mL. In comparison, the control (acarbose) is in the weak category with an IC50 value of 50-100 µg/mL.
Penyuluhan dan Edukasi Kosmetik yang Aman Bersama HIASKOS di SMKN 8 Makassar Jariah, Ainun; Utami, Yuri Pratiwi; Imrawati, Imrawati; Mustarin, Rahmah; AS, Indah Meilani; Wahyuddin, Nurzadrina; Yanti, Yuniar Dwi
Sahabat Sosial: Jurnal Pengabdian Masyarakat Vol. 4 No. 1 (2025): Sahabat Sosial: Jurnal Pengabdian Masyarakat (Desember)
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/sosisabdimas.v4i1.967

Abstract

Cosmetics are substances or preparations used on the external parts of the human body (epidermis, hair, nails, lips, and external genital organs) primarily for cleansing, perfuming, altering appearance, or improving body odor, or for protecting or maintaining the body's health. Providing counselling and education on safe cosmetics to teenagers is not just about giving beauty tips; it's a crucial step in protecting their long-term health. Adolescents are in a phase of physical and hormonal transition that makes them very concerned about their appearance, but they often lack sufficient consumer literacy to distinguish between safe and harmful products. This counselling aims to educate students to be wiser in choosing safe cosmetics. The method used is direct socialization to students at SMKN 8 Makassar, providing counselling to assess the improvement in understanding after education, direct socialization, and socialization using leaflets. The results obtained show an increase in participants' knowledge of how to choose and use appropriate and safe daily cosmetics. The conclusion of this service activity is that the counselling on safe cosmetics is highly relevant and well-received by adolescents, and it is able to improve their understanding of safe cosmetics, so similar activities can be expanded to other locations.
Antibacterial Potential of Muntingia calabura L. Ethanol Extract Against MDR Escherichia coli Yuri Pratiwi Utami; Saparuddin Latu; Rahmah Mustarin; Imrawati; Aditya Yudistira; Rahmatia
Jurnal Penelitian Pendidikan IPA Vol 11 No 12 (2025): December
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i12.7765

Abstract

Kersen leaves (Muntingia calabura L.) have long been utilized as a traditional medicinal plant used for headaches, antiseptics, antioxidants, antimicrobials, anti-inflammatories, anti-diabetics, and anti-tumors. This study aims to determine the antibacterial activity and the concentration at which kersen leaf extract can inhibit the growth of Multi Drug Resistant (MDR) Escherichia coli bacteria. The type of research conducted is a laboratory-scale experimental study. The kersen leaves were extracted using the maceration method with a 70% ethanol solvent. The antibacterial activity was tested using the agar diffusion method with sensitive and MDR Escherichia coli bacteria at varying concentrations of 1.25%, 2.5%, 5%, and 10%, conducted in three replicates and incubated for 24 hours. Subsequently, the inhibition zones were measured and the data were statistically processed. Based on the research results, at a concentration of 1.25%, an inhibition zone of 7.86 mm was obtained, at 2.5% concentration 9.65 mm, at 5% and 10% concentrations 11.93 mm and 13.98 mm on sensitive Escherichia coli bacteria, while on MDR Escherichia coli bacteria at a concentration of 1.25%, an inhibition zone of 6.51 mm was obtained, at 2.5% concentration 6.61 mm, at 5% and 10% concentrations 6.68 mm and 6.98 mm. These findings suggest that kersen leaf extract possesses moderate antibacterial activity against both sensitive and MDR E. coli, particularly at higher concentrations.
Karakterisasi Minyak Atsiri Daun Patikala (Etlingera elatior (Jack) R.m Smith) Metode Destilasi Air dengan GC-MS: Characterization of Essential Oil from Patikala Leaves (Etlingera elatior (Jack) R.m Smith) by Water Distillation Method with GC-MS Utami, Yuri Pratiwi; Imrawati, Imrawati; Bone, Mahfuzun; Amody, Zahira; Mustarin, Rahmah; Mono, Mono
Jurnal Sains dan Kesehatan Vol. 8 No. 1 (2026): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v8i1.2597

Abstract

Patikala (Etlingera elatior (Jack) R.M.Smith) is one type of plant from the Zingiberaceae family. Patikala leaves contain bioactive compounds such as polyphenols, alkaloids, flavonoids, steroids, saponins, and essential oils. Patikala leaf essential oil has the potential to be an antimicrobial and antioxidant agent. This research aims to characterize the essential oil from patikala leaves. The extraction method used water distillation and was characterized using GC-MS. The research results showed that the characteristics of essential oil obtained by water distillation method included a yield of 0.03%, organoleptic examination had a characteristic odor, was clear yellow in color, and contained active compounds such as Trans-3-caren-2-ol, p-Cymene, 1,3-Cyclopentadiene, dan 2-Cyclopenten-1-one. Based on the research, monoterpenoid essential oil was obtained. Keywords:          Essential oil, Etlingera elatior (Jack) R.M.Smith, Water distillation   Abstrak Patikala (Etlingera elatior (Jack) R.M.Smith) merupakan salah satu jenis tanaman dari suku Zingiberazeae. Daun patikala mengandung senyawa bioaktif seperti polifenol, alkaloid, flavonoid, steroid, saponin dan minyak atsiri. Minyak atsiri daun patikala berpotensi sebagai agen antimokroba dan antioksidan. Penelitian ini bertujuan untuk karakterisasi   minyak atsiri daun patikala. Metode ekstraksi menggunakan  destilasi air dan dikarakterisasi menggunakan GC-MS. Hasil penelitian yang didapatkan karakteristik minyak atsiri metode destilasi air meliputi % rendamen untuk metode sebesar 0,03%, pemeriksaan organoleptik memiliki bau khas, berwarna kuning bening dengan kandungan senyawa aktif yaitu Trans-3-caren-2-ol, p-Cymene, 1,3-Cyclopentadiene, dan 2-Cyclopenten-1-one. Berdasarkan penelitian diperoleh minyak atsiri monoterpenoid. Kata Kunci:         Minyak atsiri, daun patikala, destilasi air
Formulation and Antibacterial Evaluation of Ethanolic Garlic Peel Emulgel Against Staphylococcus aureus and Propionibacterium acnes Michrun Nisa; Sukriani Kursia; Rahmah Mustarin; Zulfiah Zulfiah; Wiranda Karmianti
Jurnal Jamu Indonesia Vol. 11 No. 2 (2026): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v11i2.451

Abstract

Garlic peel (Allium sativum L.) is a household waste that contains bioactive compounds with potential antibacterial activity. This study aimed to formulate an emulgel containing ethanolic garlic peel extract and evaluate its physical characteristics and antibacterial activity against Staphylococcus aureus and Propionibacterium acnes. The emulgel was evaluated for organoleptic properties, homogeneity, pH, and viscosity. Antibacterial activity was tested using the agar diffusion method. The formulation showed acceptable physical characteristics for topical use. The emulgel inhibited the growth of both bacteria, with inhibition zones of 12.16 mm against S. aureus and 11.02 mm against P. acnes. The antibacterial activity may be related to the presence of flavonoids, saponins, phenolic compounds, and allicin in garlic peel extract. These results suggest that garlic peel extract can be formulated into an emulgel with potential antibacterial activity.
Co-Authors Aditya Yudistira Ainun Jariah Ainun Jariah Ainun Jariah AS, Indah Meilani Astri, Andi Astri Sri Nurul Fardila Aulia Debby Pelu Benedikta Winne Angela Besse Yuliana Bone, Mahfuzun Dwi Yanti, Yuniar Haryanto Haryanto Humang, Rezki Ihsan Imrawati Imrawati Imrawati Imrawati Indri Indri Istianah Purnamasari Mahfuzun Bone Mar’atun Jannah, Imrawati, Muzakkir Baitz, Masri, Anshari Massolo, Selpi Michrun Nisa Mono, Mono Mus, Suwahyuni Nurjannah Bachri Nurzadrina Wahyuddin Rahmatia Rukman, Wira Yustika S, St. Mujahida Saldi Hapiwaty Saparuddin Latu Suhaera Sukriani Kursia Sulaiman Sulaiman Suminar, Saka Surya, Sara Thahir, Zakiah Tuti Handayani Usman, Fityatun Wahyuddin, Nurzadrina Wiranda Karmianti Yuniar Dwi Yanti Yuri Pratiwi Utami Yuyun Sri Wahyuni Yuyun Sri Wahyuni, Yuyun Sri Zahira Amody Zulfiah Zulfiah Zulkifli Zulkifli