Article Per Year (5 Year)
p-Index From 2020 - 2025
1.819
P-Index
This Author published in this journals
All Journal Health Information : Jurnal Penelitian Jurnal Pengabdian kepada Masyarakat Nusantara Journal of Experimental and Clinical Pharmacy (JECP) Pharmaceutical Reports Journal of Noncommunicable Diseases (JOND) Jurnal Katalisator JURNAL KESEHATAN YAMASI MAKASSAR Sahabat Sosial: Jurnal Pengabdian Masyarakat International Journal of Health Sciences
Rahmah Mustarin
Pharmacy Study Program, Faculty of Medicine and Health Sciences, University of Muhammadiyah Makassar
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

Published : 12 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 12 Documents
Search

 1   2 
ANTIBACTERIA ACTIVITY ETHANOL EXTRACT OF ACHRAS ZAPOTA L. FRUIT AND LAGENARIA SICERARIA (MOLINA) STANDL. AGAINST SALMONELLA TYPHI Saldi Hapiwaty; Yuri Pratiwi Utami; Imrawati; Mahfuzun Bone; Nurjannah Bachri; Rahmah Mustarin; Ainun Jariah; Zahira Amody; Benedikta Winne Angela
JURNAL KATALISATOR Vol. 9 No. 2 (2024): Jurnal Katalisator Volume 9 No.2, Oktober 2024
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v9i2.3103

Abstract

The Synergistic of antibacterial is an interaction of two antibacterial agents that produces a greater inhibitory effect on bacteria, compared to the individual antibacterial effects of the two agents. The purpose of this study was to determine the synergistic effect of anti-bacterial extract of sapodilla fruit (Achras zapota L.) and water gourd (Lagenaria siceraria (Molina) Standl.) extract against Salmonella typhi bacteria. Extraction of sapodilla fruit and water gourd fruit was carried out by maceration method using 96% ethanol (1:10). Determination of the value of the minimum inhibitory concentration (MIC) of anti-bacterial sapodilla manila fruit and water gourd fruit was carried out by the checkerboard assay method using a 96 wells microplate by calculating the Fractional Inhibition Concentration Index (FICI) value. The results showed that the single MIC value of sapodilla manila fruit and water gourd fruit respectively are 50 mg/mL and 100 mg/mL. The interaction between the two is expressed as a Fractional Inhibitory Concentration Index (FICI) with a value of 1.5. The FICI values ​​indicate different antibacterial effects of the combination of sapodilla fruit and water gourd fruit against Salmonella typhi. Keywords: Synergistic, Salmonella typhi, Achras zapota L., Lagenaria siceraria (Molina) Standl., FICI
Fraksi Daun Andong Merah (Cordyline fruticose (L.) A. Cheval) Berpotensi sebagai Sitotoksik Metode BSLT Utami, Yuri Pratiwi; Imrawati, Imrawati; Mus, Suwahyuni; Astri, Andi Astri Sri Nurul Fardila; Mustarin, Rahmah
JOURNAL OF NONCOMMUNICABLE DISEASES Vol 4, No 1 (2024): April 2024
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jond.v4i1.974

Abstract

Andong merah (Cordyline fruticosa (L.) A. Cheval) merupakan tanaman yang banyak digunakan sebagai obat tradisional. Kandungan senyawa yang ada pada tanaman andong merah berupa metabolit sekunder diantaranya polifenol, flavonoid, saponin, alkaloid, steroid dan triterpenoid sedangkan pada daun andong merah mengandung senyawa polifenol, tannin dan flavonoid. Tujuan dari penelitian ini yaitu untuk mengetahui sitotoksisitas fraksi daun andong merah (C. Fruticosa) terhadap larva udang Artemia salina Leach menggunakan metode BSLT. Ekstrak etanol 70% menghasilkan tiga fraksi yaitu fraksi n-heksan, fraksi etil asetat, dan fraksi etanol-air dengan teknik ekstraksi cair-cair (ECC) menggunakan tiga pelarut. Kemudian diuji sitotoksisitasnya dari seri konsentrasi 20 ppm, 40 ppm, 60 ppm, 80 ppm dan 100 ppm serta kontrol negatif. Hasil yang diperoleh dari penelitian ini berupa aktivitas sitotoksik fraksi dengan parameter nilai LC50 yaitu fraksi n-heksan 25,05 ppm ppm, fraksi etil aetat 85,21 ppm dan fraksi etanol-air 32,39 ppm. Kesimpulannya yakni fraksi dari daun andong merah (C. Fruticosa) termasuk dalam kategori sitotoksistas kuat. Cordyline fruticosa (L.) A. Cheval is a plant that is widely used as a traditional medicine. The compounds contained in the red oak plant are secondary metabolites including polyphenols, flavonoids, saponins, alkaloids, steroids and triterpenoids whereas in the leaves of the red andong contain compound polyphenol, tannins and flavanoids. The aim of the study was to determine the cytotoxicity of the C. fruticosa fraction to the larvae of the shrimp Artemia salina Leach using the BSLT method. The 70% ethanol extract produces three fractions namely the n-hexane fraction, the ethyl acetate fraction and the ethanole-water fraction using the liquid-liquid extraction technique (ECC) using three solvents. Then they tested their cytotoxicity from a series of concentrations of 20 ppm, 40 ppm and 60 ppm as well as negative controls. The results obtained from this study were fractional cytotoxic activity with LC50 parameters of 25.05 ppm n-hexane fraction, 85.21 ppm ethyl acetate fraction and 32.39 ppm ethanol-water fraction. The conclusion is that the fraction of the C. Fruticosa leaves belongs to the category of strong cytotoxists
Co-Authors Ainun Jariah Ainun Jariah Ainun Jariah Amody, Zahira Astri, Andi Astri Sri Nurul Fardila Benedikta Winne Angela Besse Yuliana Bone, Mahfuzun Haryanto Haryanto Humang, Rezki Ihsan Imrawati Istianah Purnamasari Mahfuzun Bone Mar’atun Jannah, Imrawati, Muzakkir Baitz, Masri, Anshari Massolo, Selpi Mus, Suwahyuni Nurjannah Bachri Nurjannah Bachri, Nurjannah Nurzadrina Wahyuddin Pratiwi Utami, Yuri Rukman, Wira Yustika S, St. Mujahida Saldi Hapiwaty Suhaera Sulaiman Sulaiman Suminar, Saka Surya, Sara Thahir, Zakiah Usman, Fityatun Usman, Yuri Pratiwi Utami Utami, Yuri Pratiwi Yuri Pratiwi Utami Yuyun Sri Wahyuni Yuyun Sri Wahyuni, Yuyun Sri Zahira Amody Zulkifli Zulkifli