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All Journal Majalah Kedokteran Bandung Indonesian Journal of Pharmaceutical Science and Technology Jurnal Farmasi Klinik Indonesia Jurnal Kartika Kimia Journal of Midwifery and Nursing JFIOnline JCPS (Journal of Current Pharmaceutical Sciences) JITEKGI Jurnal Ilmiah dan Teknologi Kedokteran Gigi ad-Dawaa : Journal of Pharmaceutical Sciences Science Midwifery Jurnal Buana Farma Jurnal Abdimas Kartika Wijayakusuma Journal of Science and Technology Research for Pharmacy Jurnal Farmasi Indonesia Kartika : Jurnal Ilmiah Farmasi Jurnal Kefarmasian Indonesia
Suci Nar Vikasari, Suci Nar
Universitas Jenderal Achmad Yani
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : Indonesian Journal of Pharmaceutical Science and Technology

 1 
Pembuatan Sabun Cairan Mengandung Susu Sapi dari Usaha Kecil Menengah di Kota Cimahi Titta Hartyana Sutarna; Wulan Anggraeni; Fikri Alatas; Regita Ayu Lestari; Faizal Hermanto; Elivas Simatupang; Afifah Bambang Sutjiatmo; Ririn Puspadewi; Lucky Rachmawan; Fahmy Ahsanul Haq; Suci Nar Vikasari
Indonesian Journal of Pharmaceutical Science and Technology Vol 9, No 1 (2022)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v1i1.28901

Abstract

Kulit merupakan salah satu bagian tubuh yang sering terpapar benda asing dan membutuhkan nutrisi dan pembersihan rutin menggunakan sabun. Susu sapi mengandung protein dan lemak yang berkhasiat untuk melembabkan dan menutrisi kulit. Penelitian ini bertujuan untuk membuat sediaan sabun cair dari susu sapi yang berfungsi untuk meningkatkan kelembaban pada kulit. Penelitian dimulai dengan pengumpulan susu sapi dari usaha kecil menengah di kota Cimahi dan uji karakteristik secara organoleptik. Selanjutnya dibuat serangkaian seri formula sabun cair yang mengandung susu sapi sebanyak 0, 5, 10 dan 20%, kemudian dievaluasi meliputi evaluasi fisik (organoleptis, pH, viskositas, dan uji stabilitas) dan pengujian terhadap responden (pengujian daya emolien dengan alat skin analyzer, uji kesukaan, dan efektivitas pembersihan). Data yang diperoleh dianalisa statistik menggunakan uji t-berpasangan. Hasil evaluasi fisik menunjukkan bahwa formula sabun cair yang mengandung susu sapi stabil selama penyimpanan 28 hari. Hasil pengujian terhadap responden menunjukkan sediaan yang paling disukai adalah sabun cair yang mengandung susu sapi 15% dengan alasan nyaman digunakan, lembut dan tidak lengket pada kulit. Hasil pengujian efektivitas pembersihan juga menunjukkan sabun cair yang mengandung susu sapi 15% dapat membersihkan kotoran dan make up.
Water Extract Influence of Stachytarpheta jamaicensis (L.) Vahl Leaves to Prevent Psoriasis Severity in Animal Model Encep Abdurahman; Nengdiana Permana; Grace S. Mardiana; Afifah B. Sutjiatmo; Anna Choirunnisa; Suci N. Vikasari
Indonesian Journal of Pharmaceutical Science and Technology Suppl. 3, No. 1 (2021)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v1i1.36335

Abstract

Psoriasis is an autoimmune disease that is characterized by the appearance of lesions on the skin. The current treatment aims to control the symptoms. The efficacy of Stachytarpheta jamaicensis (L.) Vahl’s for autoimmune rheumatoid arthritis and systemic lupus erythematosus has been tested in animal models. The aim of this research was to evaluate the effect of the water extract of S. jamaicensis leaves on psoriasis model animal (male Balb/c mice) induced topically by imiquimod. The water extract of S. jamaicensis leaves is made by boiling. The animal was divided into groups: normal, control, methotrexate 0.2 mg/kgBW, the extract (doses 25, 50 and 100 mg/kgBW). The measured parameters were the Psoriasis Area and Severity Index (PASI) score and skin histopathology. The results showed that all doses of the extract could reduce the PASI score when compared to the control group. Histological results showed that there was a decrease in keratin growth in test animals that were given the extract. Extracts at doses of 25 and 50 mg/kgBW can reduce the thickening of keratin in the epidermis of the back and ears. It can be concluded that the water extract of S. jamaicensis leaf has the most effective activity to prevent psoriasis recurrence in the dose range of 25 and 50 mg/kgBW.Keywords: Psoriasis, Stachytarpheta jamaicensis leaf water extract, PASI, keratin, imiquimod
Diuretic Effect of Combination of Watercress (Nasturtium officinale) and Purslane (Portulaca oleraceae) Sutjiatmo, Afifah Bambang; Yuliartati, Ni Luh Ade; Yulianti, Maulidya; Suryani, Suryani; Vikasari, Suci Nar
Indonesian Journal of Pharmaceutical Science and Technology Vol 10, No 3 (2023)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v10i3.36330

Abstract

Watercress (Nasturtium officinale) and purslane (Portulaca oleracea) are used to increase urination.This preclinical study aims to prove the diuretic effect of a combination of watercress and purslaneextracts. Simplisia of watercress and purslane herbs mixed with various combinations A (1:9), B(1:3) and C (1:1), then extracted in 50% ethanol. The animals were divided into five groups: control,furosemide 3.6 mg/kgBW, A 38 mg/kgBW, B 28 mg/kgBW, and C 10 mg/kgBW. Diuretic assay wascarried out using the modified Lipschitz method with the parameters observed were cumulative urinevolume for 6 and 24 hours, and potassium levels in 24-hour urine. The results showed the onset ofdiuretic effect of furosemide at 60 minutes, A at 150 minutes, B at 240 minutes and C at 90 minutes.Percent effectiveness of the diuretic in the furosemide was 718%, A 212%, B 231%, and C 368% whencompared to the controls. All combinations of extracts increased sodium and potassium secretion whencompared to controls, but this effect was not as strong as furosemide. All combinations of watercressand purslane herbs have a diuretic effect but weakly saluretic when compared to furosemide and thecombination that gives the best effect is combination C.
Co-Authors Afifah B. Sutjiatmo Afifah B. Sutjiatmo Afifah B. Sutjiatmo Afifah Bambang Sutjiatmo Afifah Bambang Sutjiatmo, Afifah Bambang Aisyah, Salmanda Akhirul Kahfi Syam Andi Supriatna Andri R. Rahmadi Andri Reza Rahmadi Anna Choirunnisa Anna Choirunnisa, Anna Ari Sri Windyaswari, Ari Sri Asri Wulandari Astuti, Niken Juni Ayu Nurfitiria Rahmi Ayu Nurfitiria Rahmi, Ayu Nurfitiria Bintussolihah, Falna Candra candra Candra Candra Dewi Lidya Ichwana Nasution Dwi Yuliana Prasita Dzikrial Sa’id ELIN YULINAH SUKANDAR Elin Yulinah Sukandar Elin Yulinah Sukandar Elivas Simatupang Elivas Simatupang Encep Abdurahman Faizal Hermanto Febrinella, Catellya Fikri Alatas Grace S. Mardiana Haq, Fahmy Ahsanul Hartyana Sutarna, Titta Ita Nur Anisa Ita Nur Anisa Khansa Rana Khalifa Kristian, Randi Kuatrina, Kuatrina Kusmaningati, Suswini Kusmayadi, Anandita Tiara Kusumawardhana, Gelar Taufiq Lucky Rachmawan Lucky Rachmawan Melani, Beta Nengdiana Permana Novia Anggraeni Hanafi Novia Anggraeni Hanafi, Novia Anggraeni Oskar Skarayadi, Oskar Pudjiastuti Kartidjo Pudjiastuti Kartidjo Puput Ayu Perdana, Puput Ayu Purwoko, Agus Rachmawan, Lucky Rahajeng, Dea Julianti Redya Hernawati Redya Hernawati, Redya Regita Ayu Lestari Ririn Puspadewi Ririn Puspadewi, Ririn Ririn Sinaga Ririn Sinaga, Ririn RR. Ella Evrita Hestiandari Setiani, Nur Asni Sheba, Shiane Hanako Shifa A. Savitri Siftiani, Nindy Dwi Simatupang, Elivas Solihah, Puspa Sari Dewi Soraya Riyanti, Soraya Sri Wahyuningsih Sujiatmo, Afifah Bambang Sulaeman Al Jati Supito, Sarasvati Sekar Ayu Suryani Suryani Syarifuddin Syarifuddin Syarifuddin Syarifuddin Syifa Khoirunnisa, Syifa Tupak, Helma Malini Marol Vina Septiani, Vina Wita Anggraeni Wulan Anggraeni Yulia Ratnawati, Yulia Yulianti, Maulidya Yuliartati, Ni Luh Ade