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All Journal HAYATI Journal of Biosciences Perspektif : Review Penelitian Tanaman Industri Indonesian Journal of Pharmaceutical Science and Technology Elkawnie Majalah Obat Tradisional Abditani : Jurnal Pengabdian Masyarakat Jurnal Ilmiah Farmasi Farmasyifa Perspektif, Review Penelitian Tanaman Industri Jurnal Abdimas Kartika Wijayakusuma Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian Riset Informasi Kesehatan AGRIC kawanad Jurnal Medika: Medika Kartika : Jurnal Ilmiah Farmasi Medical Sains : Jurnal Ilmiah Kefarmasian Pharmacon: Jurnal Farmasi Indonesia Jurnal Farmasi Galenika
Akhirul Kahfi Syam
Fakultas Farmasi Universitas Jenderal Achmad Yani
Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Control & Systems Engineering Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Riset Informasi Kesehatan

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Traditional uses, phytochemistry, pharmacology activity and plant tissue culture of ficus carica l. (a mini review) Fahrauk Faramayuda; Sigid Pamungkas Wicaksono; Akhirul Kahfi Syam; Soraya Riyanti; Ari Sri Windyaswari; Yeni Karlina; Elfahmi Elfahmi
Riset Informasi Kesehatan Vol 11 No 1 (2022): Riset Informasi Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (276.464 KB) | DOI: 10.30644/rik.v11i1.537

Abstract

Ficus carica L. or Figs plants are plants originating from the Middle East and the Mediterranean region, which then spread to various parts of the world through explorers who try to plant in various countries. Figs plants can grow in various habitats, including infertile rocky soils, forests, shrubs, and even hot dry soils. Figs plants have several varieties that can be distinguished from the shape of the stem, the shape of the leaves, and the fruit's color. Figs plants are widely used as traditional medicine for both leaves and fruit. Noted in several countries have used the Figs plant as one of the plants used for traditional medicine. Figs plants are widely used for antioxidants, anticancer, hepatoprotective, antidiabetic, antibacterial, antipyretic, antituberculosis, antispasmodic antiplatelet in several countries. Figs plants contain secondary metabolites of alkaloids, latexonins, phenols, and flavonoids. There is one method of multiplication of Figs plants that began to be widely used, namely plant tissue culture. Plant tissue culture is a method of propagation using tissue slices or parts of plants that are small and in aseptic conditions. Several studies have been obtained to trace figs plants by tissue culture methods using slices of leaves and shoots.
Uji antioksidan dan bioaktivitas fraksi etil asetat batang jarak tintir (Jatropha multifia L.) Akhirul Kahfi Syam; Julia Ratnawati; Desti Hermawati; Puspita Satriyani Permatasari Surasa
Riset Informasi Kesehatan Vol 9 No 1 (2020): Riset Informasi Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30644/rik.v9i1.329

Abstract

Abstrak Latar Belakang: Jatropha multifida L. atau jarak tintir merupakan tanaman yang digunakan secara empiris getahnya sebagai obat luka oleh masyarakat Indonesia sejak lama. Penelitian ini merupakan lanjutan dari penelitian sebelumnya mengenai batang jarak tintir yang telah diuji toksisitas dengan metode BSLT dan peredaman antioksidan dengan metode DPPH yang secara berturut memberikan nilai LC50 terendah 3,69 µg/mL dan IC50 56,85 µg/mL pada ekstrak etil asetat. Metode: Penelitian meliputi tahap-tahap pengumpulan bahan uji batang jarak tintir, penyiapan simplisia, pembuatan ekstrak dengan 3 pelarut yang berbeda kepolarannya penapisan fitokimia dari simplisia, fraksinasi menggunakan metode Kromatografi Cair Vakum (KCV) dari ekstrak etil asetat menjadi 4 fraksi. Hasil: Hasil pengujian antioksidan metode peredaman DPPH memberikan IC50 terhadap f1 (n-heksan 75%:etil asetat 25%), f2 (n-heksan 50%:etil asetat 50%), f3 (n-heksan 25%:etil asetat 75%), dan f4 (etil asetat 100%) secara berturut-turut adalah 3759,79 µg/mL; 790,94 µg/mL; 167,41 µg/mL; dan 164,82 µg/mL. Hasil pengujian BSLT terhadap fraksi etil asetat memberikan hasil LC50 sebesar f1 64,43 µg/mL; f2 37,54 µg/mL; f3 41,94 µg/mL; dan f4 25,70 µg/mL. Kesimpulan: F4 merupakan fraksi dengan nilai IC50 dan LC50 yang paling rendah dari seluruh fraksi, yang menunjukkan f4 merupakan fraksi yang paling aktif sebagai antioksidan dan BSLT serta diduga golongan flavonoid yang diketahui dari profil kromatogram KLT dengan Rf 0,57 yang memberikan hasil positif terhadap penampak bercak FeCl3 dan AlCl3 merupakan senyawa aktif dari kedua aktifitas tersebut. Kata kunci: Antioksidan, Brine Shrimp Lethality Test, DPPH, Jatropha multifida L. ANTIOXIDANT AND BIOACTIVITY ASSAYS OF ETHYL ACETATE FRACTION OF JARAK TINTIR STEM (Jatropha multifida L) Abstract Background: Jatropha multifida L. or jarak tintir was empirically used as wound treatment for the sap by Indonesian people for a long time ago. The toxicity and antioxidant capacity of the jarak tintir stem was done by brain shrimp lethality test (BSLT) with LC50 3,69 µg/mL and DPPH scavenging activity with IC50 56,85 µg/mL for ethyl acetate extract. Method: Extraction was performed by continuous extraction with Soxhlet apparatus using various polarity solvents (n-hexane, ethyl acetate, and methanol) and ethyl acetate extract was fractioned by vacuum liquid chromatography (VLC) into 4 fraction with gradien eluen of n-hexane and ethyl acetate. Results: Antioxidant assay gave IC50 for f1 (n-hexane 75%:ethyl acetate 25%), f2 (n-hexane 50%: ethyl acetate 50%), f3 (n-hexane 25%: ethyl acetate 75%), and f4 (ethyl acetate 100%) respectively as 3759,79 µg/mL; 790,94 µg/mL; 167,41 µg/mL; and 164,82 µg/mL. BSLT assays for each fractions gave LC50 as f1 64,43 µg/mL; f2 37,54 µg/mL; f3 41,94 µg/mL; and f4 25,70 µg/mL. Conclusion: Fraction 4 was the best fraction with the lowest IC50 and LC50 with flavonoid was suspected as responsible compound for both assays after TLC analysis that gave spot with Rf 0.57 and gave positive result after sprayed with FeCl3 dan AlCl3 spray reagent. Keywords: Antioxidant, Brine Shrimp Lethality Test, DPPH, Jatropha multifida L
Co-Authors Adinda Fitriani Adinugraha, Irham M. Akbar, Tzazkia Febriyana Amedea, Esanda Zulfi Ami Soega Dwigantina Ananda Tunjung Pertiwi Anggita Esa Putri Fitrichia Anna Choirunnisa Anna Choirunnisa, Anna Aprilia, Trialisa Ari Sri Windyaswari Ari Sri Windyaswari Ari Sri Windyaswari Ari Sri Windyaswari, Ari Sri Azhar, Farah Salsabilla Saidah Dadan Suryasaputra Desti Hermawati Dewi, Renti Mutiara Dewilestari, Meyra Pratami Dwi Ayu Pratiwi Dwigantina, Ami Soega Elfahmi Elfahmi, Elfahmi Ema Mutya Esanda Zulfi Amedea Fahrauk Faramayuda Fahrauk Faramayuda, Fahrauk Faizal Hermanto Farah Salsabilla Saidah Azhar Faramayudha, Fahrauk Farhan Febrinella, Catellya Fitriani, Adinda Fitrichia, Anggita Esa Putri Florence Meliawaty Handayani, Dewi Ratih Hermawati, Desti Hestiary Ratih Ismail, Nursafira Khairunnisa Jaka Permana Julia Ratnawati Julia Ratnawati Julia Ratnawati Julia Ratnawati, Julia Juliastuti, Henny Khaerunnisa, Rahmadaniah Komar Ruslan Wirasutisna Lahagu, Helga Nitulo Berliana Limbong, Remare Halomoan Mardiana, Grace Selly Meyra Pratami Dewilestari Muhamad Insanu Muhammad Irwan Mutya, Ema Nandi Agustian Pertiwi, Ananda Tunjung Pratiwi, Dwi Ayu Purwoko, Agus Puspita Satriyani Permatasari Surasa Putri, Dhiffa Namira Alifia Rahaju, Asih Rakhmat, Iis Inayati Ramdhani, Amalia Kusuma Remare Halomoan Limbong Renata Ananda Marthasedana Renti Mutiara Dewi Sabilia, Syahra Asfi Sabirin, Indah Puti R. Septiani, Usi Septiani, Vina Sheila Nur Hasanah Sheila Nur Hasanah Sigid Pamungkas Wicaksono Soraya Riyanti Soraya Riyanti Soraya Riyanti Soraya Riyanti, Soraya Sri Restu Andriyani Suci Nar Vikasari, Suci Nar Sufyan Zainul Arifin Sukrasno Suntana, Mutiara Sukma Surasa, Puspita Satriyani Permatasari SURYANI Totik Sri Mariani Trialisa Aprilia Usi Septiani Vina Septiani Wulan Anggraeni Wulandari, Yesi Yeni Karlina Yeni Karlina Yeni Karlina, Yeni Yesi Wulandari Yuslianti, Euis Reni