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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Penelitian Pendidikan IPA (JPPIPA) Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) Jurnal Pendidikan Biolearning Journal Jurnal Abdimasa PREPOTIF : Jurnal Kesehatan Masyarakat Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Jurnal Promotif Preventif Jurnal Kesehatan Tambusai JOURNAL LA MEDIHEALTICO International Journal of Health, Economics, and Social Sciences (IJHESS) Jurnal EduHealth Jurnal Sains dan Teknologi Sci-Tech Journal Jurnal Ilmiah Ilmu Terapan Universitas Jambi Jurnal Etnofarmasi Jurnal Mahasiswa Ilmu Kesehatan Journal of Public Health and Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Ilmu Kesehatan
Lukman Hardia
Universitas Pendidikan Muhammadiyah Sorong
Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Pengaruh Sosiodemografi Terhadap Keberhasilan Pengobatan Pasien TB-RO di RSUD Dr. J. P. Wanane Tutuhatunewa, Priscillia Ryani; Hardia, Lukman; Irwandi
Jurnal Kesehatan Tambusai Vol. 5 No. 3 (2024): SEPTEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i3.32421

Abstract

Tuberkulosis (TB) merupakan penyakit menular yang disebabkan oleh bakteri Mycobacterium tuberculosis, penggunaan obat secara berulang dan lama seringkali menyebabkan pasien kurang patuh terhadap terapi yang mengakibatkan resisten. Indonesia masih berada di posisi penderita TB ke-2 terbanyak setelah India dengan perkiraan TB-RO sebanyak 37.197, Papua barat menempati peringkat ke-12 secara nasional dalam penemuan kasus TB-RO sebanyak 47% dengan Kabupaten Sorong menduduki peringkat terakhir angka success rate TB dari 10 Kabupaten/kota di Provinsi Papua Barat yaitu 25% (Dinas Kesehatan Provinsi Papua Barat, 2019). Tujuan penelitian ini adalah mengetahui hubungan antara variabel sosiodemografis dengan keberhasilan pengobatan terapi pengobatan pasien TB-RO di poliklinik TB DOTS RSUD Dr. J. P. Wanane. Penelitian observasional dengan desain cross sectional dan teknik sampling yaitu total sampling. Penelitian dilaksanakan dari bulan mei hingga juni 2024 di RSUD Dr. J. P. Wanane Kabupaten Sorong. Data yang didapat yaitu terdapat 100 orang penderita TB-RO tahun 2020-2023, sampel yang sesuai dengan kriteria inklusi sebanyak 55 orang. Analisis data menggunakan uji chi square, dengan faktor sosiodemografi berhubungan dengan keberhasilan pengobatan jika nilai P<0,05. Hasil analisis mendapatkan nilai antara umur (P = 1), jenis kelamin (P = 0,157), tingkat pendidikan (P = 0,166), jarak ke RSUD (P = 0,639), status pekerjaan (P = 1), suku (P = 0,867), penyakit komorbid (P = 1). Dari hasil analisis menunjukkan bahwa umur, jenis kelamin, tingkat pendidikan, jarak ke RSUD, status pekerjaan, suku dan penyakit komorbid tidak memiliki hubungan dengan keberhasilan pengobatan pasien TB-RO tahun 2020-2023 di RSUD Dr. J. P. Wanane Kabupaten Sorong.
Research Trends of Stunting Related to Insulin-Like Growth Factor-1: Bibliometric Analysis Hardia, Lukman; Pratama, Agus Sangka; Muslihin, A. M.
Jurnal Penelitian Pendidikan IPA Vol 9 No SpecialIssue (2023): UNRAM journals and research based on science education, science applic
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9iSpecialIssue.6903

Abstract

Stunting is a condition in which a person's height is less than normal based on age and gender. The prevalence of stunting in Indonesia in 2021 is 24.4%. This illustrates that stunting is still a problem that cannot be resolved in Indonesia. Research on the incidence of stunting was carried out to determine its relationship with insulin-like growth factor-1 (IGF-1) levels. Search results on the Pubmed database obtained 446 English-language articles published from 1993 – April 12, 2023. The results of bibliometric analysis and VOSViewer show that new research trends began to be seen in 2018 to 2023 even though there had been publications previously in 1993 and 2000, but very minimal amount. The most dominating document types were journal articles with 310 publications (69.51%) and reviews with 89 publications (19.96%). The most trending keywords are humans (268), female (176), male (145), animals (142), insulin-like growth factor i/metabolism (94), child (74), adult (60), mice (56), pregnancy (47) and child preschool (43). The publishing journals that published the most articles were Frontiers in Endochronolgy (22 publications), International Journal of Molecular Sciences (19 publications), Scientific Reports (13 publications). The highest number of author collaborations is from the USA with 78 articles being the country with the most collaboration on both SCP and MCP with an MCP to SCP ratio of 0.244. China ranks second with the number of articles of 63 with an MCP ratio of 0.190.
Anthocyanin Compounds from Ethanol Extract of Red Fruit (Pandanus conideus L.): A Functional Group Analysis Rizky, Indah Amelia; Budiyanto, Angga Bayu; Hardia, Lukman
Jurnal Penelitian Pendidikan IPA Vol 10 No 11 (2024): November
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i11.9321

Abstract

Red Fruit (Pandanus conoideus L.) is a typical Papuan plant that is rich in bioactive compounds such as anthocyanins, which have the potential to act as antioxidants. This research aims to analyze the chemical structure of anthocyanin compounds from red fruit ethanol extract using Fourier Transformed Infrared (FTIR) spectroscopy. FTIR is a spectroscopic tool widely used to characterize or detect functional groups and qualitatively identify compounds in samples. Anthocyanins act as antioxidants and have various biological activities such as preventing cancer, cardiovascular disease, and diabetes. Extraction was carried out using the maceration method using 70% ethanol solvent, and characterization was performed using FTIR in the wave range 4000-450 cm⁻¹. The results of the research that has been carried out show that the ethanol extract of red fruit contains secondary metabolites such as flavonoids, alkaloids, and saponins. The FTIR results of red fruit extract show the presence of functional groups characterized by the presence of the O-H, C-O-C, C-O, and C=C functional groups which are important indicators of the antioxidant properties of anthocyanins. This research confirms the potential of Red Fruit as a natural source of anthocyanins which are useful as antioxidants
In Vitro Study of The Activity of Yellow Rope (Anamirta cocculus) Extract As An Antibacterial Tumpu, Darmayanti; Muslihin, A.M.; Hardia, Lukman
Jurnal Penelitian Pendidikan IPA Vol 11 No 4 (2025): April
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i4.10753

Abstract

A. cocculus is an endemic plant to Papua, which is often used as medicine. This study aims to determine the antibacterial activity of the ethanol extract of A. cocculus stems against P. acne, S. aureus, and E. coli bacteria. This research also has the potential to be used as a contextual learning resource in biology classes, especially on the topic of antibacterial and secondary metabolite testing, using experimental methods. The antibacterial activity test was carried out using the disk diffusion method, which was performed in 3 concentrations, namely 5%, 10%, and 15%. The positive control used 2 μg of clindamycin antibiotic and 30 μg of chloramphenicol antibiotic; the negative control used Aqua Pro injection. Measurement of the diameter of the inhibition zone shows that A. cocculus extract can inhibit bacterial growth, concentration 5% (P. acnes = 9.18mm/medium; S. aureus = 9.17/medium, and E. coli = 3.91/weak), concentration 10% (P. acnes = 11.86mm/strong; S. aureus = 11.88/strong, and E. coli = 5.17mm/medium), and concentration 15% (P. acnes = 11.56/strong; S. aureus = 12.9/strong, and E. coli = 5.86/medium).
Antibacterial Activity Testing of Methanol Extract of Yellow Rope Barb (Anamirta cocculus) Nurwahida, Wa Ode; Muslihin, A.M.; Hardia, Lukman
Jurnal Penelitian Pendidikan IPA Vol 11 No 4 (2025): April
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i4.10760

Abstract

Indonesia has abundant natural wealth. One of the endemic plants of Papua which is often used in traditional medicine is yellow rope (A. cocculus). This study aims to determine the antibacterial activity of methanol extract of yellow rope bark (A. cocculus) against P. acnes, S. aureus, and E. coli bacteria using an experimental microbiological approach in the laboratory, and the experiment model may also serve as a contextual laboratory-based learning resource in microbiology education. The antibacterial activity test was carried out using the disc diffusion method which was made in 3 concentrations, namely 5%, 10% and 15%. The results of measuring the diameter of the inhibition zone showed that each concentration was able to inhibit the growth of P. acnes bacteria with an average diameter of 2,816 mm (Weak), 6,733 mm (Medium), 9,333 mm (Medium), and control (+) clindamycin 2 μg 14,483 mm (Strong). S. aureus bacteria with an average diameter of 3.133 mm (Weak), 6.35 mm (Medium), 8.235 mm (Medium) and control (+) clindamycin 2 μg 20.97 mm (Very strong). E. coli bacteria showed an average diameter of 3.875 mm (Weak), 6.175 mm (Medium), 8.566 mm (Medium) and control (+) ciprofloxacin 5 μg 20.783 mm (very strong). This research shows that the methanol extract of yellow stem bark (A. cocculus) has antibacterial activity.
Co-Authors A. M. Muslihin Achmad Noerkhaerin Putra Akrom, Akrom Angga Bayu Budiyanto Anisa, Meilinda Arif Radhika Mentari Arni, Veni Zafi Assem, Vincentia Santy Astuti, Ratih Arum Budianto, Angga Bayu Dion Fahcrul Rozi Eka Savira Ni'ma Arfiani Erawati, Rika Eva Maya Sari Fabanyo, Syahrul H. fania, vikafania Irwandi Irwandi Irwandi Irwandi Irwandi Irwandi Irwandi Jannah, Aulia Mifthakul Lanipi, Retna Parica Lanipi, Retna Paricca Levina Virginia M Natsir Djide Mansyur Arief Maulana, Fajar Meilinda Anisa Muh Ishar Difinubun Nanik Sulistyani Ningrum, Indah Diah Nurwahida, Wa Ode Nurwahyuni Pratama, Agus Sangka putri puspitawati, devyana Rahayu, Dika Rizky, Indah Amelia Sanaky, Nazla Wati Sarifuddin, Nuhidayah Siska Siska Siti Fatma Z.F. Sun, Suny Syahrul H. Fabanyo Titiek Suhardi Haripurnomo Kushadiwijaya Hidayati Tuasikal, Rasi Fitri Yanti Tumpu, Darmayanti Tunnazilah, Nurhikmah Tutuhatunewa, Priscillia Ryani ulandari, clarista windi Umpain, Agnes Nesa Wasaraka, Fadila Alfiah Watora, Wahyuni Wiwik, Wiwik Triyani Yapsenang, Amar Jansen Yuniatri, Nur Khusna Yusnita La Goa Zf, Siti Fatma