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Jeffrey ., Jeffrey
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Antibacterial and Antifungal Activities of the Leaf Extracts of Mentha piperita L. Jeffrey, Jeffrey; Nasution, Dewi Lidya Ichwana; Zakaria, Myrna Nurlatifah; Fitriani, Anisa; Junir, Aurorin Silvia
Majalah Kedokteran Bandung Vol 48, No 1 (2026)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v58.4368

Abstract

Herbal medicines are increasingly used due to the presence of bioactive compounds with antibacterial and antifungal properties. This study aimed to evaluate the antibacterial and antifungal effects of Mentha piperita L. extract against Porphyromonas gingivalis and Candida albicans. A laboratory-based experimental study with a post-test only control group design was conducted. The test organisms were exposed to M. piperita L. extract at concentrations of 3.125%, 6.25%, 12.5%, 25%, 50%, and 100%. The antibacterial and antifungal activities were evaluated using the agar well diffusion method to determine inhibition zones, followed by broth dilution tests to identify the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC), and Minimum Fungicidal Concentration (MFC). Statistical analysis was performed using one-way ANOVA with a significance level of p<0.05. Results showed that all concentrations inhibited the growth of both microorganisms, with MIC values of 12.5% and 25% for P. gingivalis and C. albicans, respectively. The MBC for P. gingivalis and MFC for C. albicans were both observed at 100%. There were significant differences (p<0.05) in the inhibition zones across the concentrations tested. In conclusion, Mentha piperita L. extract demonstrates significant antibacterial and antifungal activities against Porphyromonas gingivalis and Candida albicans, suggesting its potential as a natural antimicrobial agent for oral infections.
Co-Authors Agung Novianto, Agung Ahmad Faried Andik Yulianto Atthoriq, Adriansyah Altaf Azis, Rizal Badi Soerachman, Badi br. Sembiring, Rehulina Brar, Dylan Amrirtraj Candra, Tony Darwis, Rudi S. Destra, Edwin Didik Priyandoko Djohan, Frita Ferlita Shafri Dohude, Priscilla Putri Derlian Elvis, Elvis Enda Noviyanti Simorangkir Engellika, Giovanny Evalyn, Elsa Ferdiansyah, Rival Fitriani, Anisa Florence Meliawaty Fransella, Kezia Friska, Inge Gultom, Helmida Hadyanto Lim Handoko, Miranda Silvia Harry Murti Herlen, Aldo Hesniati, Hesniati Johnson, Johnson Jordan, Stella Juli Jamnasi Junir, Aurorin Silvia Koswara, Caroline Kurniawan, Joshua Lau, Wilsen Laurence, Jenniver Liliana Liliana Lumban Raja, Alex Maruli Tua Maryam, Khaulah Mega, Juli Yosa Muhtar, Azmi Nur Azizah Myrna N. Zakaria, Myrna N. Myrna Nurlatifah Zakaria, Myrna Nurlatifah Nainggolan, Ita Margaretha Namira Ufrida Rahmi Nasution, Dewi Lidya Ichwana Novamaura, Regyta Panggabean, Kristina Dameria Qlintang, Sandy RAHMAT, DENI Ramadhan, Moh S. S. Riana, Amalia Satyanagara, William Gilbert Siahaan, Dwi Lunarta Doderina Sihite, Fiorella Natalia Kinanti Stefanny, Stefanny Stendy, Stendy Te, Richardson Teresa Liliana Wargasetia Tham, Vincent Tichvy Tammama, Tichvy Triharsiwi, Dwi Nur Vanessa, Jolin Vanomy, Afrianti Elsye Vina, Vina Vinna Kurniawati Sugiaman, Vinna Kurniawati Viorensa, Viorensa WAHYU WIDOWATI Warizky, Nanda T. Yogie, Giovanno Sebastian Yohanes Firmansyah Yuslianti, Euis Reni Zhang, Sherles