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All Journal As-syifaa Jurnal Farmasi Indonesian Journal of Pharmaceutical and Clinical Research Pharmaceutical Reports Jurnal Pengabdian Masyarakat Bhinneka JURNAL PENGABDIAN MASYARAKAT YAMASI Borneo Journal of Pharmacy Celebes Journal of Community Services Indonesian Journal of Jamu MPSJ Jurnal Balireso: Jurnal Pengabdian pada Masyarakat
Rais Razak, Rais
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences Other

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Journal : Pharmaceutical Reports

 1 
In Vitro Anti-Inflammatory Activity of Bajakah Tampala Root (Spatholobus littoralis Hassk.) Maskur, Sri Karina; Tahir, Masdiana; Razak, Rais
Pharmaceutical Reports Vol 4, No 1 (2025): (March) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v4i1.358

Abstract

Bajakah tampala root (Spatholobus littoralis Hassk.) contains phenolic compounds, flavonoids, tannins, terpenoids and saponins. Flavonoid compounds have pharmacological effects, namely anti-inflammatory. The purpose of this study was to determine the anti-inflammatory activity of ethanol extract of bajakah tampala root by inhibiting protein denaturation in vitro using UV-Vis spectrophotometer and diclofenac sodium as positive control. The extract was prepared by maceration method using 96% ethanol solvent. The results showed that the ethanol extract of bajakah tampala root had a percentage of inhibition of 31.27% at the lowest concentration (10 ppm) and 43.28% at the highest concentration (50 ppm) with an IC50 value of 77.92 µg/mL and the ic50 value of diclofenac sodium is 12.26 µg/mL. The percentage of inhibition that is more than 20% is considered to have inhibitory power in the protein denaturation process. So, it can be concluded that the ethanol extract of bajakah root has potential as an anti-inflammatory.
Antioxidant Activity of Ethanol Extract of Kepok Banana Peel (Musa paradisiaca L.) by Ferric Reducing Antioxidant Power Method Damang, Irda Binti; Suhaenah, Asriani; Razak, Rais
Pharmaceutical Reports Vol 4, No 2 (2025): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v4i2.379

Abstract

Antioxidants are compounds capable of neutralizing the harmful effects of oxidants by donating electrons to unstable molecules, thereby preventing oxidative damage. These compounds play a vital role in protecting biological systems from oxidative stress, which is associated with aging and various chronic diseases. Kepok banana (Musa paradisiaca Linn.) peel is an underutilized natural resource rich in secondary metabolites such as saponins, flavonoids, alkaloids, tannins, and quinones, many of which are known for their strong antioxidant potential. The present study aimed to evaluate the antioxidant activity of the ethanol extract of kepok banana peel using the Ferric Reducing Antioxidant Power (FRAP) method. Extraction was performed by maceration with 96% ethanol as the solvent to obtain a concentrated extract. The FRAP assay was carried out by reacting the extract with FRAP reagents and measuring the absorbance using a UV–Vis spectrophotometer at a maximum wavelength of 710 nm. Quercetin was used as a standard antioxidant reference, producing a calibration curve with a linear regression equation of y = 0.0203x + 0.0301 and a correlation coefficient (r) of 0.9965, indicating excellent linearity. The results revealed that the ethanol extract of kepok banana peel exhibited high antioxidant capacity, with a value of 81.6939 mgQE/g extract. These findings suggest that kepok banana peel is a promising natural source of antioxidants and could potentially be developed into functional ingredients for pharmaceutical and nutraceutical applications.
Sulfonamide Residue in the Broiler Chicken Circulating in Makassar Fawwaz, Muammar; Razak, Rais; Tahir, Masdiana; Permatasari, Andi; Amula, Andi Tenri; Seniwati, Seniwati
Pharmaceutical Reports Vol 1, No 2 (2022): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (443.376 KB) | DOI: 10.33096/pharmrep.v1i2.169

Abstract

The use of sulfonamide related to drug residual in the product of broiler chicken, like meat and egg. This research aimed to determine the sulfonamides (sulfamerazine, sulfanilamide, and sulfadiazine) on the broiler chicken meat, breast, and egg from the three different slaughterhouses circulating in the City of Makassar. The sample was extracted by acetonitrile and acetone then concentrated. The extract and sulfonamides then analyzed by HPLC method using C18 reverse phased column, UV-Visible detector in the wavelength of 270 nm. The result of study shows that the chromatogram of sample breast and egg has similar retention time with sulfonamides as a standard reference. The breast sample contains sulfamerazine residues, sample B and C contains 0.014 and 0.005 % (w/w), respectively. The egg sample A and D contains sulfadiazine 0.045 and 0.108 % (w/w), respectively. Sample B contains sulfanilamide 0.053 % (w/w). Sample A and B is egg yolk, while sample D is egg whites. Based on the results obtained, this is not suitable for the rules set by JECFA of 0.1 mg/kg (10-5 % w/w) as well as the standard of SNI. It can be concluded that generally broiler chicken breast and egg circulating in the City of Makassar was contaminated by sulfonamide with high concentration.
Co-Authors A Amaliah Dahlia A, Aridha Abd. Malik Aco Mappacanda, Aco Ahmad, Akstar Roskiana Ahmad, Aktsar Roskiana Amaliah Dahlia, Andi Aminah Aminah Amriati Syarif, Rezki Amriati Syarif, Rezky Amriati, Rezki Amula, Andi Tenri Andi Emelda Andika, Yusrianti Asfar, Akbar Asni Amin Asriani Suhaenah Astika, Elvina Audia Triani Olii, Audia Triani Damang, Irda Binti Eka Putri, Andi Yuyun Faradiba Faradiba Feralia, Feralia Harti Widiastuti Irma Santi, Irma Kamase, Jeni M, Murti Nurhidayah Mamat Pratama, Mamat Masdiana Tahir Maskur, Sri Karina Masmor, Elvira Mochammad Imron Awalludin Muammar Fawwaz Murfat, Moh Zulkifli Muzakkir Baits, Muzakkir Permatasari, Andi Putri, Anggi Dwi RAHMAN, ANDI AMALIA RAMADHANI Rahmawati Rahmawati, Rahmawati Ririn Ririn Risda Waris, Risda Selpida Handayani, Selpida Seniwati Seniwati, Seniwati St Maryam, St St. Maryam, St. Sudarman Virsa Handayani Wisdawati, Wisdawati Yulianto, Yuni Zakinah Zainal Abidin