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All Journal Klinikal Sains (Jurnal Analis Kesehatan) Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Medika Malahayati Journal Health & Science : Gorontalo Journal Health and Science Community PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat JURNAL ANALIS LABORATORIUM MEDIK Jurnal Analis Farmasi Borneo Journal of Medical Laboratory Technology Medfarm: Jurnal Farmasi dan Kesehatan Jurnal Kesehatan Tambusai JAF (Jurnal Analis Farmasi) Formosa Journal of Science and Technology (FJST) Proceeding ISETH (International Summit on Science, Technology, and Humanity) Jurnal Sains dan Kesehatan Sains Medisina Health Research Journal of Indonesia Jurnal Kefarmasian Indonesia
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Anticholesterol Activity of Combined Binahong and Keji Beling Leaf Extracts in Mice (Mus musculus) Eka Septia Nur Rizky; Ganea Qorry Aina; Nursalinda Kusumawati; Eka Farpina
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 2 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i2.684

Abstract

Cholesterol is a type of lipid found in the human body, with approximately 80% produced endogenously by the liver and the remaining 20% obtained from dietary sources. Elevated total cholesterol levels in the blood increase the risk of various health conditions such as cardiovascular disease, obesity, hypertension, and even stroke. Prolonged elevation can lead to plaque formation in blood vessels, resulting in impaired circulation and potentially life-threatening complications. The use of synthetic cholesterol-lowering drugs is often associated with unwanted side effects, including liver toxicity, muscle pain, and gastrointestinal disturbances. This has prompted increasing interest in safer, natural alternatives such as herbal medicine, which is perceived to provide fewer side effects and additional health benefits. This study aimed to investigate the anti-cholesterol activity of a combination of Binahong (Anredera cordifolia) and Keji Beling (Strobilanthes crispus) leaf extracts in mice (Mus musculus) induced with a high-cholesterol diet. The extraction method employed was maceration, using 96% ethanol as the solvent to ensure optimal phytochemical yield. The experimental design consisted of five groups: a negative control group, a positive control group, and three treatment groups receiving combinations of Binahong and Keji Beling extracts in ratios of 1:1, 1:3, and 3:1. Total cholesterol levels were measured using the Point of Care Test (POCT) method. The results showed that all treatment groups experienced a significant reduction in total cholesterol levels (p = 0.001 < 0.05). The most effective reduction was observed in the 1:1 ratio group, with a decrease of 45.39%, followed by the 3:1 group (27.80%) and the 1:3 group (14.17%). These findings indicate strong potential for development as an effective and safe herbal alternative for lowering cholesterol levels.
Studi In Vivo Kombinasi Herbal Keji Beling, Binahong, dan Madu Kelulut terhadap Penyembuhan Luka Diabetik Hewan Model Ganea Qorry Aina; Nursalinda Kusumawati; Tiara Dini Harlita; Wirid Triana Dawam
Sains Medisina Vol 4 No 2 (2025): Sains Medisina
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/snsmed.v4i2.847

Abstract

Diabetes melitus adalah gangguan metabolik yang ditandai dengan tingginya kadar gula dalam darah (hiperglikemia) akibat penurunan sekresi insulin oleh pankreas, berkurangnya sensitifitas insulin, atau keduanya. Salah satu komplikasi yang sering terjadi adalah gangrene/ulkus, yaitu terjadi kerusakan integritas pada kulit yang disebabkan oleh gangguan sirkulasi perifer sehingga jaringan sekitar luka akan mati atau nekrotik dan mengalami pembusukan. Penggunaan bahan herbal sebagai obat luka terus dikembangkan dalam penelitian maupun pemanfaatannya, diantaranya adalah daun binahong (Anredera cordifolia (Ten.) Steenis), keji beling (Strobilanthes crispus Bl.), dan madu kelulut. Penelitian ini bertujuan untuk melihat efektifitas pemberian ekstrak daun binahong, daun keji beling, dan madu kelulut terhadap penyembuhan luka diabetik menggunakan hewan uji yaitu mencit putih jantan. Penelitian ini merupakan jenis penelitian eksperimen murni. Setelah mencit diberi perlakuan, pengukuran diameter luka dimulai pada hari ke-0, 5, 10 dan 15. Hasil penelitian ini kemudian dianalisis menggunakan SPSS versi 25. Hasil uji statistik dengan uji One Way Anovamenunjukan nilai p <0,05 yaitu 0,000 yang berarti pemberian kombinasi herbal memiliki pengaruh terhadap penyembuhan luka diabetes. Selanjutnya dilanjutkan uji lanjutan yaitu Uji Duncan’s Multiple Range Test dengan hasil perlakuan yang paling efektif yaitu pemberian kombinasi ekstrak daun binahong dan daun keji beling.
Identifikasi Bakteri Nosokomial Pada Tempat Tidur Pasien Ruang Perawatan Anak RSUD Inche Abdoel Moeis Samarinda Reva Medyana; Tiara Dini Harlita; Nursalinda Kusumawati; I Gede Andika Sukarya
Health Research Journal of Indonesia Vol 4 No 6 (2026): Health Research Journal of Indonesia
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/hrji.v4i6.1635

Abstract

Pendahuluan: Infeksi yang didapatkan saat pasien menerima perawatan di fasilitas medis dikenal sebagai infeksi nosokomial, atau infeksi terkait perawatan kesehatan (HAIs). Terutama di bangsal pediatrik tempat anak-anak dengan sistem kekebalan tubuh yang belum matang berada, tempat tidur pasien dapat berfungsi sebagai reservoir bagi mikroorganisme yang menyebabkan infeksi. Tujuan: Mengidentifikasi bakteri yang berpotensi menyebabkan infeksi nosokomial pada permukaan tempat tidur pasien di Ruang Perawatan Anak RSUD Inche Abdoel Moeis Samarinda. Metode: Penelitian observasional deskriptif menggunakan 40 sampel swab permukaan kasur yang diambil dengan teknik total sampling. Identifikasi bakteri dilakukan melalui kultur pada media Blood Agar dan MacConkey Agar, dilanjutkan pewarnaan Gram dan uji biokimia. Hasil: Seluruh sampel (100%) menunjukkan pertumbuhan pada Blood Agar, sedangkan (57,5%) tumbuh pada MacConkey Agar. Bakteri Gram negatif lebih dominan (57,5%) dibandingkan Gram positif (42,5%). Spesies yang ditemukan meliputi Pseudomonas sp. (30%), Staphylococcus aureus (22,5%), Klebsiella sp. (12,5%), Streptococcus sp. (10%), Bacillus sp. (10%), Acinetobacter sp. (7,5%), dan Citrobacter sp. (7,5%). Simpulan: Permukaan tempat tidur pasien di ruang perawatan anak terkontaminasi berbagai bakteri yang berpotensi menyebabkan infeksi nosokomial, dengan dominasi Pseudomonas sp.
Edukasi Keamanan Kosmetik bagi Remaja di Wilayah Harapan Baru Kota Samarinda: Cosmetic Safety Education for Adolescents in Harapan Baru, Samarinda City Tiara Dini Harlita; Ganea Qorry Aina; Sresta Azahra; Nursalinda Kusumawati; Dewi Saraswati
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 11 No. 7 (2026): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v11i7.12541

Abstract

The increase in cosmetic use among adolescents is supported by the development of social media and the ease of purchasing cosmetic products online. A wide range of information on beauty trends is readily accessible to adolescents, encouraging them to experiment with various cosmetic products. However, not all adolescents fully understand the safety aspects and potential risks of contamination, including heavy metals and microbes, associated with the cosmetics they use, especially with long-term use. This situation underscores the importance of providing educational interventions to enable adolescents to make informed decisions and use cosmetic products safely and legally. The purpose of this community service program was to enhance adolescents’ knowledge and awareness of cosmetic safety, particularly among adolescents in Harapan Baru, Samarinda City. The education was conducted face-to-face through interactive lectures and discussions, followed by pretest and posttest evaluations involving 25 participants. The results showed an increase in the average score from 7.24 to 17.12 after the intervention, with a mean improvement of 9.88 points. The Wilcoxon test indicated a statistically significant difference between pretest and posttest scores (p < 0.001). Communicative and contextual education has proven effective in improving adolescents’ understanding of cosmetic safety.
Co-Authors Agustina Setia, Skolastika Agustina, Shella Aina, Ganea Qorry Anggrieni, Nurul Annisa Nur Rizky Azahra, Sresta Azhari, Charisa Maylani Putri Damayanti, Sulpinah Dewi Saraswati Dwi Wulan Sari Eka Farpina Eka Farpina Eka Septia Nur Rizky Farpina, Eka Ganea Qorry Aina Ganea Qorry Aina Haryoto Haryoto Haryoto, H Herman, Jumria Heru Sudarmanto I Gede Andika Sukarya Jannah, Alnur Miftahul Jannahtun Safitri Kesuma, Suryanata Khotimah, Cantika Khusnul Laila, Siti Nurul Lamri Lamri Makkadafi, Suparno Putera Maulina, Rida Peni Indrayudha Reva Medyana Rosyad, Muhammad Naufal Sari, Nur Permata Sresta Azahra Sri Wahyunie Sulistiawati, Retri Yaumil Supri Hartini, Supri Tiara Dini Harlita Tiara Dini Harlita Tiara Dini Harlita Wirid Triana Dawam