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All Journal English Review: Journal of English Education Jurnal Biologi Tropis Jurnal Pengabdian Magister Pendidikan IPA Inteligensi : Jurnal Ilmu Pendidikan Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Prisma Sains: Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram Lambda: Jurnal Ilmiah Pendidikan MIPA dan Aplikasinya Bakti Sekawan : Jurnal Pengabdian Masyarakat Journal of Authentic Research
Pauzan Pauzan, Pauzan
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Physics Public Health Social Sciences Other

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Gambaran Profil Lipid pada Peminum Kopi di Dusun Sembung Daye Kecamatan Narmada, Lombok Barat Sukmana, Dhika Juliana; Suhada, Adriyan; Noortiningsih, Noortiningsih; Camin, Yeremiah Rubin; Pauzan, Pauzan; Suhaela, Nursani
Journal of Authentic Research Vol. 1 No. 2 (2022): July
Publisher : LITPAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/jar.v1i2.825

Abstract

Kebiasaan merokok, mengonsumsi alkohol dan kafein membawa dampak yang tidak baik bagi kesehatan. Nikotin yang terkandung dalam rokok dapat meningkatkan sekresi dari katakolamin sehingga meningkatkan lipolisis. Kafein tidak langsung meningkatkan metabolisme energi dalam tubuh.  Konsumsi jangka panjang akan menekan metabolisme energi yang dapat menyebabkan kelelahan adrenal dan berpengaruh buruk pada keseimbangan profil lipid. Penelitian ini dilakukan untuk mengetahui gambaran profil lipid peminum kopi di Dusun Sembung Daye. Penelitian ini merupakan penelitian dengan desain cross sectional dan melibatkan 60 orang responden dengan kriteria peminum kopi, pekerjaan yang seragam dan usia produktif. Sampel darah yang diperoleh kemudian diperiksa di Laboratorium RSUD Patut Patuh Patju, sedangkan data kelompok kontrol diperoleh dari hasil pemeriksaan Laboratorium Klinik Vi Diagnostic Mataram. Intrumen yang digunakan untuk mendapat data sekunder berupa kuisioner kemudian bersamaan dengan data profil lipid dianalisis secara statistic menggunakan SPSS (uji t dan chi kuadrat). Dari penelitian ini diperoleh kadar kolesterol total, trigliserida, High Density Lipoprotein dan Low Density Lipoprotein peminum kopi secara berturut-turut adalah 183,67 mg/dL, 174,75mg/dL, 47,943 mg/dL dan 107,50 mg/dL. Sedangkan untuk kelompok kontrol 174,80 mg/dL, 118,20 mg/dL, 40,075 mg/dL dan 114,68 mg/dL. Hasil analisis statistik menggunakan uji t dan chi kuadrat menunjukkan adanya perbedaan kadar trigliserida dan HDL pada kelompok peminum kopi dengan kelompok kontrol, dimana kadar trigliserida dan HDL kelompok peminum kopi lebih tinggi.  Kadar kolesterol total dan LDL kedua kelompok tidak berbeda. Kafestol dan kafein yang terdapat pada kopi meningkatkan trigliserida dan cenderung tidak memengaruhi kolesterol total dan LDL, sedangkan asam klorogenat pada kopi memiliki efek sebagai antioksidan yang meningkatkan kadar HDL. Profil Lipid on Coffee Drinker in Sembung Daye Village  Subdistrict of Narmada, West Lombok Abstract The habit of smoking and consuming alcohol and caffeine has an impact that is not good for health. The nicotine in cigarettes can increase the secretion of catecholamines, thereby increasing lipolysis. Caffeine does not directly increase energy metabolism in the body. Long-term consumption will suppress energy metabolism, which can cause adrenal fatigue and adversely affect the balance of lipid profiles. This study described the lipid profile of coffee drinkers in Sembung Daye Hamlet. The research used a crcross-sectional design and involved 60 respondents with the criteria of coffee drinkers, uniform work and productive age. The blood samples obtained were then examined at the Patut Patuh Patju Hospital Laboratory. At the same time, the control group data were obtained from the results of the Vi Diagnostic Mataram Clinic Laboratory. The instrument used to obtain secondary data in the form of a questionnaire and then the lipid profile data were analyzed statistically using SPSS (t test and chi-square). From this study, the total cholesterol, triglyceride, High-Density Lipoprotein, and Low-Density Lipoprotein levels of coffee drinkers were 183.67 mg/dL, 174.75mg/dL, 47.943 mg/dL and 107.50 mg/dL, respectively. While for the control group 174.80 mg/dL, 118.20 mg/dL, 40.075 mg/dL and 114.68 mg/dL. The results of statistical analysis using t and chi-square tests showed differences in triglyceride and HDL levels in the coffee drinker group and the control group, where triglyceride and HDL levels in the coffee drinker group were higher. Total and LDL cholesterol levels were not different between the two groups. The caffeine and caffeine found in coffee increase triglycerides and tend not to affect total and LDL cholesterol, while the chlorogenic acid in coffee has an antioxidant effect that increases HDL levels.
Gerakan Sehat Tanpa TB: Edukasi Kekebalan dan Cek Kesehatan di Dusun Dasan Bawak, Desa Lelede Pauzan, Pauzan; Pertiwi, Ajeng Dian; Halid, Idha
Jurnal Pengabdian Magister Pendidikan IPA Vol 8 No 2 (2025): April-Juni 2025
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmpi.v8i2.11755

Abstract

Tuberculosis (TB) remains one of the major public health issues in Indonesia, particularly in rural areas with limited access to healthcare services and medical information. The activity titled "Healthy Movement Without TB: Immunity Education and Health Check-Up" was conducted in Dusun Dasan Bawak, Lelede Village, as a promotive and preventive effort to curb the spread of TB. This program included community education on the importance of the immune system in fighting TB infection, promotion of clean and healthy living habits, and free health check-ups covering basic medical examinations and TB symptom screening. The implementation methods involved interactive lectures and direct examinations by medical personnel. The results showed an increase in community knowledge regarding TB and the importance of maintaining a strong immune system, as well as high enthusiasm in participating in the health check-ups. This intervention is expected to be an initial step toward creating a more health-conscious community that actively participates in TB prevention.
Antioxidant Activity of Ethanol Extract Combination of Cavendis Banana Peel (Musa acuminata) and Kepok Banana Peel (Musa paradisiaca) Using the DPPH Method Suhada, Adriyan; Ulya, Tuhfatul; Fardani, Roushandy Asri; Pertiwi, Ajeng Dian; Halid, Idham; Pauzan, Pauzan; Ratulangi, Wulan Ratia; Indriani, Nurul; Ariwidiani, Ni Nyoman; Widyan, Rosnalia; Utami, Evi Fatmi; Novianty, Wanda
Prisma Sains : Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram Vol 13, No 3: July 2025
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/j-ps.v13i3.15782

Abstract

Banana peels are often considered waste despite being rich in bioactive compounds with potential as natural antioxidants. This study aimed to evaluate the antioxidant activity of an ethanol extract combination of Cavendis banana peel (Musa acuminata) and Kepok banana peel (Musa paradisiaca) using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method. The extraction process was conducted using 96% ethanol maceration, yielding an extraction efficiency of 9.13%. Phytochemical screening revealed the presence of flavonoids, tannins, saponins, and steroids/terpenoids in the extract. Antioxidant activity was assessed through the DPPH method, resulting in an IC50 value of 6.47 ppm and an AAI value of 5.40, classified as very strong antioxidants. These results are comparable to the positive control (Vitamin C), which had an IC50 value of 6.29 ppm and an AAI value of 5.56. The findings suggest that the ethanol extract combination of Cavendis and Kepok banana peels has significant potential as a natural antioxidant source applicable in the food, pharmaceutical, and cosmetic industries. Recommendations for future research include optimization of extraction methods, isolation of key active compounds, in vivo testing, and functional product formulation development to maximize the extract's potential.
Inflammatory Response of Tumor Necrosis Factor-alpha (TNF-α) in Incised Wounds of White Rats (Rattus norvegicus) Induced by Aloe vera Extract Pauzan, Pauzan
Jurnal Biologi Tropis Vol. 25 No. 2 (2025): April-Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i2.9441

Abstract

Incised wounds are common injuries that trigger an inflammatory response, in which Tumor Necrosis Factor-alpha (TNF-α) plays a crucial role in the pathogenesis. Aloe vera has long been recognized for its wound-healing potential; however, its molecular mechanisms particularly in modulating TNF-α expression remain incompletely understood. This study aims to investigate the effect of Aloe vera extract on TNF-α expression in incised wounds of white rats. This experimental study employed a controlled group design, involving a positive control group (K+), a negative control group (K−), and a treatment group (P), each consisting of five white rats. Incised wounds were created on the dorsum of the rats, and the treatment group received topical Aloe vera extract. TNF-α expression was evaluated using immunohistochemical methods on days 3, 7, and 14 post-wounding. The treatment group that received Aloe vera extract showed a significant decrease in TNF-α expression compared to the negative control group on days 7 and 14. Aloe vera extract modulates TNF-α expression in incised wounds of white rats, indicating its potential as a therapeutic agent in wound healing through anti-inflammatory mechanisms.
ANALYZING SYMPTOMS AND CAUSING FACTORS OF SPEAKING ANXIETY IN ENGLISH PRESENTATIONS AMONG UNIVERSITY STUDENTS Juwaidah, Afrida; Pauzan, Pauzan; Rahmat, Hery; Khusniyah, Nurul Lailatul; Hisyam, Ibnu
Inteligensi : Jurnal Ilmu Pendidikan Vol 8, No 1 (2025)
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33366/ilg.v8i1.6851

Abstract

Speaking anxiety is a significant challenge faced by students in English presentations. Students who experience anxiety during presentations exhibit various symptoms and influenced by multiple factors. This study aims to analyze the symptoms and causal factors of speaking anxiety among a state university students, particularly those participating in the English Camp organized by the English Study Club. This research employs a qualitative descriptive approach to explore students' experiences related to speaking anxiety. Data were collected through semi-structured interviews, observations, and questionnaires during the English Camp. The questionnaire was adapted from the Foreign Language Classroom Anxiety Scale (FLCAS) to identify students with high levels of anxiety. Selected students were then interviewed and observed to identify the symptoms and factors contributing to their anxiety. The findings that speaking anxiety manifests in observable symptoms, categorized into physical symptoms (trembling, a pale face and rigid facial expression), verbal symptoms (voice shaking, frequently using filler words), and observable symptoms in the form of action. Meanwhile, non-observable symptoms include nervousness; heart palpitations; difficulty in thinking, forgetting material, and mind blank; experiencing a cold sensation. The primary causing factors of students’ speaking anxiety include lack of vocabulary, lack of preparation, lack of practice, fear of making mistakes and being laughed at, fear of being the focus of attention and memory disassociation.
Profile Anti-Inflammatory Mechanisms of Moringa Leaves: A Review of Preclinical and Clinical Studies Pauzan, Pauzan
Jurnal Biologi Tropis Vol. 25 No. 3 (2025): Juli-September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i3.9244

Abstract

Moringa oleifera leaves have long been recognized in traditional medicine for their anti-inflammatory properties. This review aims to comprehensively evaluate current scientific evidence from both preclinical and clinical studies regarding the anti-inflammatory mechanisms of moringa leaves. A systematic search of the literature was conducted using databases such as PubMed, Scopus, and Google Scholar, covering studies published up to 2025. Preclinical findings indicate that moringa leaf extracts exhibit significant anti-inflammatory activity through various mechanisms, including inhibition of prostaglandin synthesis, suppression of pro-inflammatory cytokines such as TNF-α and IL-6, and modulation of the NF-κB signaling pathway. In vivo animal models further demonstrate reductions in edema and inflammatory cell infiltration. Early-phase clinical trials suggest potential therapeutic benefits in managing mild to moderate inflammatory conditions; however, these studies remain limited in scale and methodological rigor. In conclusion, moringa leaves show promising and multifaceted anti-inflammatory mechanisms, warranting further large-scale clinical validation to support their use as a complementary therapeutic agent.
Antimicrobial Activity of Starfruit Leaf Extract Against Gram-Positive and Gram-Negative Bacteria Pauzan, Pauzan; Kurniawan, Edy; Hafisah, Nurul
Jurnal Biologi Tropis Vol. 25 No. 3 (2025): Juli-September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i3.9418

Abstract

Starfruit (Averrhoa bilimbi L.) is a plant traditionally used as medicine, mainly due to its secondary metabolite content that has the potential as an antimicrobial agent. This study aims to evaluate the antimicrobial activity of A. bilimbi leaf extract against Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli bacteria. Extraction was carried out using three types of solvents: 100% ethanol, 100% ethyl acetate, and a mixture of ethanol-ethyl acetate (1:1) using the maceration method. Antimicrobial activity tests were carried out using the disc diffusion method to measure the inhibition zone of bacterial growth. The results showed that all A. bilimbi leaf extracts had inhibitory activity against both types of test bacteria. The extract with ethyl acetate solvent showed the largest inhibition zone against S. aureus and E. coli, followed by the mixed ethanol-ethyl acetate extract, and then the ethanol extract. These findings indicate that the active compounds in A. bilimbi leaves are more soluble in ethyl acetate and have the potential to be developed as natural antibacterial agents.
The Role and Regulation of Natural Killer (NK) Cells in Chemotherapy: A Literature Review Pauzan, Pauzan
Jurnal Biologi Tropis Vol. 25 No. 3 (2025): Juli-September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i3.9465

Abstract

Natural Killer (NK) cells, as innate immune effectors capable of targeting tumor cells without prior sensitization, interact complexly with chemotherapy, which can both enhance and suppress their functions. This literature review aims to comprehensively evaluate the role and regulation of NK cells in the context of chemotherapy over the past decade. Literature searches were conducted through Google Scholar, PubMed, Scopus, and Web of Science databases using relevant keywords. The review findings indicate that several chemotherapeutic agents can enhance NK cell activity by increasing the expression of activating ligands on tumor cells and promoting the release of pro-inflammatory cytokines. However, chemotherapy may also suppress NK cell function through systemic immunosuppression and alterations in the tumor microenvironment. NK cell-based immunotherapy, especially when combined with chemotherapy, demonstrates promising therapeutic potential. Recent studies support the development of strategies such as genetic modification, exogenous cytokine administration, and NK cell engineering to improve therapeutic efficacy. This review underscores the importance of further research to optimize the synergy between NK cells and chemotherapy in cancer treatment.
Antioxidant Activity of Ethanol Extract Combination of Cavendis Banana Peel (Musa acuminata) and Kepok Banana Peel (Musa paradisiaca) Using the DPPH Method Suhada, Adriyan; Ulya, Tuhfatul; Fardani, Roushandy Asri; Pertiwi, Ajeng Dian; Halid, Idham; Pauzan, Pauzan; Ratulangi, Wulan Ratia; Indriani, Nurul; Ariwidiani, Ni Nyoman; Widyan, Rosnalia; Utami, Evi Fatmi; Novianty, Wanda
Prisma Sains : Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram Vol. 13 No. 3: July 2025
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/j-ps.v13i3.15782

Abstract

Banana peels, often considered agricultural waste, are rich in bioactive compounds with significant antioxidant potential. This study evaluates the antioxidant activity of a combined ethanol extract from Cavendis (Musa acuminata) and Kepok (Musa paradisiaca) banana peels using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. The extraction was performed via maceration with 96% ethanol, yielding 9.13%. Phytochemical analysis identified key compounds including flavonoids, tannins, saponins, and steroids/terpenoids, which are known to exhibit antioxidant properties. The extract demonstrated strong radical scavenging activity with an IC50 of 6.47 ppm and an Antioxidant Activity Index (AAI) of 5.40, comparable to Vitamin C (IC50 = 6.29 ppm; AAI = 5.56). These results indicate a synergistic effect from combining the two banana peel varieties, enhancing antioxidant efficacy beyond that reported for individual peels. This study supports the potential use of Cavendis and Kepok banana peel extracts as sustainable natural antioxidants for application in food preservation, nutraceuticals, and cosmetics. Future work should focus on optimizing extraction methods, detailed phytochemical profiling, stability assessment, and in vivo validation to advance product development and maximize health benefits.
Profile of the Anti-inflammatory Mediator Interleukin-10 (IL-10) in Patients Suspected of Covid-19 Pauzan, Pauzan; Kurniawan, Edy
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7658

Abstract

Severe acute respiratory syndrome corona virus 2 (SARSCOV-2) is a virus that causes corona virus desease (Covid-19), namely a respiratory sindrome desease that comes from the beta corona virus group. A serious problem with Sarscov-2 infection is when a cytokine storm appears which is produced as the body’s response to an inflammatory reaction, but the presence of interleukin (cytokine)-10 as an anti-inflammatory cytokine can suppress inflammatory reactions to avoid cytokine storms. The study's objective was to characterize IL-10 levels in people who may have Covid-19. The research method is to use an analytical survey with a retrospective design. Interleukin-10 levels were measured utilizing the ELISA (Enzime Linked Immunosorbant Assay) method. Result: The average level of IL-10 in SARSCOV-2 utilizing the Real Time Polymerase Chain Reaction (RT-PCR) method to detect positive Covid-19 suspect samples (83.16 pg/ml) was higher than SARSCOV-2 negative Covid-19 suspects (81.03 pg/ml). Conclusion: the comparison of IL-10 levels in positive Covid-19 suspects and negative Covid-19 suspects using the RT-PCR technique has an insignificant difference in levels because naturally Pro- and anti-inflammatory cytokines' reciprocal responses show that the immune response of the samples from suspected Covid-19 patients used is still very strong (IL-10).  
Co-Authors Adriyan Suhada Ajeng Dian Pertiwi Ajeng Dian Pertiwi, Ajeng Dian Ardiansyah, Lalu Dwi Sartia ARI KURNIAWAN Bustanul Atfal Camin, Yeremiah Rubin Didi Taswidi Dini Eka Fitriani Dini Qurrata Ayuni Edy Kurniawan, Edy Fardani, Roushandy Asri Hafisah, Nurul Halid, Idha Hery Rahmat Hisyam, Ibnu Idham Halid Ismatullah, Nurul Khatimah Juwaidah, Afrida Kurniawati, Ari Mentari, Ika Nurfajri Mindi Richia Putri Mohamad Sadli Muhadi, Muhadi Musparlin Halid Ni Nyoman Ariwidiani Noortiningsih Noortiningsih Novianty, Wanda Nurul Hadiatun Nurul Indriani Nurul Lailatul Khusniyah Permana, Yan Reiza Prihartini, Dita Rachman, Muhammad Aditya Rahmi Ramadhan Ratulangi, Wulan Ratia Reni Chairunnisah, Reni Rian Wahyul Ikhtiar Ribahan Ribahan Rosnalia Widyan Suhaela, Nursani Sukmana, Dhika Juliana Suyitno Suyitno Syamsuriansyah, Syamsuriansyah Ulya, Tuhfatul Utami, Evi Fatmi