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All Journal Althea Medical Journal Interest : Jurnal Ilmu Kesehatan Jurnal Keterapian Fisik Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Skala Kesehatan Journal of Health Science and Prevention Journal of Telenursing (JOTING) Jurnal Kebidanan JOSING: Journal of Nursing and Health MALANG JOURNAL OF MIDWIFERY (MAJORY) Jurnal WIDYA LAKSMI (Jurnal Pengabdian Kepada Masyarakat) Jurnal Pengabdian Mandiri Jurnal Bakti Untuk Negeri Jurnal Rakat Sehat : Pengabdian Kepada Masyarakat Jurnal Kebidanan Jurnal Kebidanan Bestari Jurnal Pengembangan Potensi Laboratorium EKOBIS ABDIMAS : Jurnal Pengabdian Masyarakat Jurnal Teknokes KESMAS UWIGAMA: Jurnal Kesehatan Masyarakat Optimal Midwife Journal
Norlaila Sofia
Banjarmasin Health Polytechnic
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Eczema and Food Allergies in Children: A Systematic Review of Developmental Outcomes Noor Adha Aprilea; Norlaila Sofia; Rusmilawaty Rusmilawaty; Vonny Khresna Dewi; Lulu Salaya
Interest : Jurnal Ilmu Kesehatan INTEREST: Jurnal Ilmu Kesehatan Volume 15 Issue 1 May 2026
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37341/interest.v15i1.781

Abstract

Background: Pediatric eczema (atopic dermatitis; AD) and food allergies (FA) are rising globally and share immune pathways that extend harm beyond the skin to growth, cognition, and social development—yet no synthesis has examined all three developmental domains exclusively using primary empirical evidence. This systematic review aimed to determine whether children with AD and/or FA exhibit: (1) impaired physical growth; (2) adverse cognitive and neurodevelopmental outcomes; and (3) elevated rates of behavioral and social difficulties compared to unaffected peers. Methods: A systematic search of MEDLINE, Embase, Scopus, Web of Science, and grey literature repositories identified 210 records after deduplication. Following title/abstract screening and full-text review of 98 articles, 35 primary empirical studies—spanning diverse designs—met inclusion criteria. Systematic and narrative reviews were excluded. Results: Twenty-two of 35 studies reported impaired physical growth, including lower height, weight, BMI, and head circumference z-scores, with 18 reaching statistical significance. Deficits were most pronounced in children with severe or persistent disease and multiple allergen restrictions. Cognitive and neurodevelopmental impacts were identified in 13 studies, with effects varying by developmental domain and disease severity. Behavioral and social difficulties appeared in 10 studies, predominantly linked to severe disease and sleep disruption. Conclusion: Eczema and food allergies impair child development through interconnected immune, nutritional, and psychosocial pathways. Multidisciplinary care and early intervention are essential; clinicians should routinely refer affected children to pediatric dietitians. Future research should prioritize large longitudinal studies incorporating standardized neurodevelopmental assessments and biomarkers.
Co-Authors Agus Rachmadi Ahmad Rizani Asy-Syifa Nashriyah Asy-Syifa Nashriyah Bisepta Prayogi, Bisepta Eddy Fadlyana Ezliana, Ezliana Ferry Fadli Fratama Hapisah Hapisah, Hapisah Imanuddin, M. Rizki Isnaniah, Isnaniah Isrowiyatun Daiyah Januarsih Januarsih Januarsih Khairir Rizani, Khairir Krisnadi, Sofie Lulu Salaya Magdalena Mahpolah Mahpolah, Mahpolah Megawati Megawati - Megawati Megawati Nashriyah, Asy-syifa Noor Adha Noor Adha Aprilea Norhalisa, Norhalisa Nur Rohmah Nur Rohmah Nur Rohmah Prihatanti Pratiwi Sri Handayani Prihatanti, Nur Rochmah Prihatanti, Nur Rohmah Puteri, Siti Noor A'in A'fifah Rafidah Rafidah raudatul jannah Rita Kirana Rohmah Prihatanti, Nur Rubiati Hipni Rusmilawaty Setyorini Irianti suhrawardi, suhrawardi Susiarno, Hadi Tri Tunggal, Tri Tut Barkinah Vonny Khresna Agung Suhadi Mohammad Hakimi Dewi YUNIARTI YUNIARTI Zakiah Zulfikar Ali As Zulfikar Ali As, Zulfikar Ali