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Pembekalan Edukasi Pengetahuan Penyakit Degeneratif dengan Penanaman-Pemanfaatan tanaman Toga Serta Perilaku Hidup Bersih dan Sehat (PHBS) Kepada Masyarakat Cawang RT 009 dan RT 011 Waluyo, Dyah Ayuwati; Krismayadi, Krismayadi; Purnomo, Frida Octavia; Hanan, Raihan Arung; Pramesti, Anggi Shiva; Nusantarawati, Eka; Mulyani, Hanny Dwicahya; Tsabitah, Nadiah; Adiningsih, Septia Nur Wahyu
Jurnal Mandala Pengabdian Masyarakat Vol. 5 No. 1 (2024): Jurnal Mandala Pengabdian Masyarakat
Publisher : Progran Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpm.v5i1.356

Abstract

One of the problems that exists in the people of Kampung Cawang RT 09 & 11 RW 13, Kramat Jati Village, East Jakarta City is a lack of awareness, but quite a few people in Kampung Cawang have basic knowledge regarding degenerative diseases, what are the examples of the disease, the symptoms of each generative disease and how possible therapies can be applied both medically and non-medically, therefore counseling related to degenerative diseases is the main program that has been implemented during the KKN process. Lack of awareness of the potential around them which they might be able to use as additional resources to be useful for Cawang village community education. One of the programs implemented in Cawang village is apart from counseling about degenerative diseases, there are also other programs including counseling about drug classification, how to store drugs, how to wash hands properly and several other additional programs that support the creation of good relationships between students (participants). KKN) with the people of Cawang Village. The objectives of holding this program are: 1) To create public awareness of the importance of science; 2) To create basic knowledge regarding degenerative diseases; 3) To encourage and motivate people to know the importance of science and maintaining health and to be able to cultivate toga independently. The result of this outreach program is that the community is enthusiastic in participating in this activity. Apart from that, this outreach program can also help people who have difficulty understanding the basics of degenerative diseases and maintaining health.
Study of kinetic and adsorption isotherm of ibuprofen on mcm-41 synthesized with rice husk Hartono, Olyvia Azzahra Putri; Purnomo, Frida Octavia; Waluyo, Dyah Ayuwati; Alam, Tunas; Madiabu, Mohammad Jihad
Pharmaciana Vol. 14 No. 2 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i2.27393

Abstract

Rice husk is one of the abundant wastes, especially in agricultural countries. Rice husk waste has asilica content of 95.80%, where the silica content can be utilized to make an adsorbent. One of theadsorbents that can be made is Mobil Composition of Matter 41 (MCM-41), a material with ahexagonal structure with a surface area to adsorb ibuprofen. Based on the results of the research thathas been done, MCM-41 synthesized with rice husk has the same characterization results as MCM-41synthesized with commercial materials tetraethyl orthosilicate (TEOS). Fourier Transform InfraredSpectroscopy (FTIR) characterization results show the absorption peak is at wave number 1068.58 cm1 which shows asymmetric Si-O-Si stretching vibrations and at 799.60 cm-1region is symmetric Si-OSi stretching vibrations. X-ray diffraction (XRD) characterization results show an hexagonal crystalform at 20 = 20o-30o. Scanning Electron Microscope (SEM) characterization results show particle of2,664 um. Based on the results of the research that has been done MCM-41 synthesized from rice huskcan adsorb ibuprofen with Langmuir isotherm approach and Pseudo Second Order kinetics, and themaximum adsorbing capacity is 34.48 mg/g
ANALISIS EFEKTIVITAS BIAYA TERAPI KOMBINASI PADA PASIEN RAWAT JALAN DENGAN DIABETES MELITUS TIPE 2 DI RSU SWASTA JAKARTA SELATAN Lukitasari, Nurraya; Waluyo, Dyah Ayuwati; Purnomo, Frida Octavia; Wardana, Mutia Sari; Rahmawati, Icha
Jurnal Kesehatan Tambusai Vol. 5 No. 2 (2024): JUNI 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i2.28018

Abstract

Diabetes Mellitus (DM) adalah salah satu penyakit tidak menular yang menjadi masalah kesehatan global yang mengalami peningkatan angka kesakitan dan kematian tertinggi di dunia termasuk di Indonesia. Penatalaksanaan terapi pada pasien dengan DM tipe 1 menggunakan insulin merupakan pilihan utama, sedangkan indikasi untuk obat diabetes oral terutama ditujukan untuk mengobati pasien dengan DM tipe 2 yang tidak dapat dikendalikan dengan mengatur asupan energi, karbohidrat, dan olahraga Terapi insulin adalah salah satu pilihan tambahan pada pasien DM tipe 2 jika langkah pertama pengobatan yang menggabungkan kebiasaan gaya hidup dan obat diabetes oral tidak mencapai target HbA1c yang diinginkan Berbagai jenis kombinasi obat antidiabetes yang diberikan kepada pasien, antara lain kombinasi 2 obat antidiabetes oral, kombinasi insulin dengan 1 obat antidiabetes oral, kombinasi insulin dengan 2 obat antidiabetes oral atau bahkan kombinasi 2 jenis insulin dengan antidiabetes oral. Penelitian ini akan memberikan informasi menyeluruh mengenai efektivitas biaya antidiabetes baik oral maupun insulin terhadap luaran klinis Gula Darah Sewaktu (GDS) yang diamati selama tiga bulan terapi pada pasien diabetes rawat jalan di suatu rumah sakit umum di Jakarta Selatan. Diperoleh hasil terapi kombinasi Acarbose+Gliquidone dengan nilai REB yang baik yaitu Rp 6.027,06 disusul dengan terapi Levemir pen+Acarbose+Glibenklamid+Metformin dan Novorapid pen+Gliquidone masing-masing sebesar Rp 12.532,14 dan Rp 12.638,28. Nilai RIEB terapi kombinasi Acarbose+Metformin+Gliquidone perlu menambahkan biaya sebesar Rp 905,82 per peningkatan efektivitas.
POTENSI EKSTRAK DAUN BELIMBING WULUH (AVERRHOA BILIMBI L.) DALAM PENGHAMBATAN BAKTERI STAPHYLOCOCCUS EPIDERMIDIS DAN PROPIONIBACTERIUM ACNES Waluyo, Dyah Ayuwati; Febriyanti, Dina; Putri, Azkharien Meydiana; Halimatushadyah, Ernie; Purnomo, Frida Octavia
Jurnal Kesehatan Tambusai Vol. 5 No. 2 (2024): JUNI 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i2.28316

Abstract

Edukasi Pengobatan Batuk Pilek pada Siswa-Siswi Sekolah Kami di Kota Bekasi Septiani, Septiani; Waluyo, Dyah Ayuwati; Yoelianto, Yassmin Athaya; Rau, Vio Eklesia Yulia; Lisapaly, Marlen; Amalia, Hanifa; Sulastri, Lusi; Yani, Yuni Ay; Akbar, M. Ali; Mardlotillah, Daffa; Maghribi, Berlian Setya; Mundari, M. Masum
Mosaic: Jurnal Pengabdian Kepada Masyarakat Vol. 1 No. 3 (2024): December 2024
Publisher : Lontara Digitech Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61220/mosaic.v1i3.518

Abstract

Flu biasa atau batuk pilek adalah jenis Infeksi Saluran Pernapasan Akut (ISPA) yang sangat umum di masyarakat. Swamedikasi merupakan upaya pengobatan yang dilakukan sendiri, biasanya dilakukan untuk mengatasi keluhan-keluhan dan penyakit ringan yang banyak dialami masyarakat, seperti demam, nyeri, pusing, batuk, influenza, sakit maag, cacingan, diare, penyakit kulit dan lain-lain. Obat-obatan yang umumnya digunakan untuk swamedikasi dikenal sebagai obat tanpa resep atau obat bebas. Obat bebas ini dapat diperoleh di berbagai tempat seperti warung, apotek, dan supermarket. Sementara itu, obat-obatan yang harus diperoleh melalui resep dokter disebut obat resep. Edukasi kepada masyarakat, khususnya siswa di Sekolah Kami, menjadi sangat penting untuk memastikan mereka memiliki pemahaman yang benar tentang penggunaan obat, mampu menyaring informasi yang valid, dan tidak terpengaruh oleh promosi obat yang menyesatkan. Metode yang digunakan dalam kegiatan pengabdian ini adalah penyuluhan, yang bertujuan untuk meningkatkan pemahaman dan kesadaran siswa-siswi di Sekolah Kami. Peserta kegiatan ini adalah siswa SD kelas 1 sampai SD kelas 6 dan siswa SMP kelas 1 sampai SMP kelas 3 Setelah kegiatan penyuluhan dilakukan, hasil post-test menunjukkan peningkatan yang signifikan, dengan rata-rata 91,4% responden berhasil menjawab soal dengan benar. Hasil kegiatan ini memperlihatkan bahwa edukasi dapat berdampak positif pada pengetahuan siswa-siswi tentang kesehatan, terutama dalam mengenali penyakit umum seperti batuk pilek serta meningkatkan literasi kesehatan siswa dan membantu mereka melakukan swamedikasi yang aman.
Ethanolic extract of Parkia speciosa Hassk leaves innovation of gastroretentive tablet: standardization and optimization Nurfitriyana, Nurfitriyana; Fitriya, Fitriya; Fithri, Najma Annuria; Putri, Dwi Kurnia; Lestari, Siti Marwah; Waluyo, Dyah Ayuwati; Syarif, Hardiyanti
JURNAL ILMU KEFARMASIAN INDONESIA Vol 23 No 2 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i2.1461

Abstract

Parkia speciosa ethanol leaves extract contains flavonoid, tannin, and terpen as ulcus peptic remedy. These compounds exhibit limited activity in the stomach due to the short gastric residence time following oral administration. The formulation of gastroretentive tablets can overcome this limitation. This research aims to control the prolonged release of drugs in the stomach to increase bioavailability and characterize the ethanol leaves extract. Extraction was carried out by maceration using ethanol, followed by standardization based on specific and non-specific parameters extract. Gastroretentive tablet was formulated with combination of HPMC-K4M and chitosan using factorial design 22. Effects of compositional factors and their interactions on gastroretentive tablet was observed on hardness, friability, floating lag/duration time, swelling index, and mucoadhesive time. Results standardization extract showed that extract met the required criteria for both specific parameters (organoleptic properties and phytochemical screening) and non-specific parameters (moisture content, loss on drying, water/ethanol-soluble extract content). Based on with DX®10 analysis, the optimum formulation was achieved with 20.25% of HPMC-K4M and 10.26% of chitosan. The analysis of the optimum formulation characteristics was as follows: friability (0.22%), hardness (29.53 N), mucoadhesive time (22.86 hours), floating lag/duration time (27.54 minutes; 12 hours), and swelling index (312.82%). Result revealed that gastroretentive tablets formulated with ethanol extract of Parkia speciosa leaves improve gastric residence duration and promote better bioavailability.
“Menginsipirasi Menjadi Apoteker” Pengabdian Masyarakat Di SMK Tunas Bangsa Krismayadi; Dyah Ayuwati Waluyo; Ernie Halimatushadyah; Aji Humaedi
Jurnal Pengabdian Masyarakat Mandira Cendikia Vol. 4 No. 12 (2025)
Publisher : YAYASAN PENDIDIKAN MANDIRA CENDIKIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70570/jpkmmc.v4i12.2022

Abstract

Kegiatan pengabdian kepada masyarakat bertajuk “Indahnya Menjadi Apoteker” dilaksanakan oleh Program Studi Farmasi Universitas Binawan di SMK Tunas Bangsa, Jakarta. Kegiatan ini dilatarbelakangi oleh rendahnya minat generasi muda terhadap profesi apoteker, padahal profesi ini memiliki peran penting dalam pelayanan kesehatan dan industri farmasi. Tujuan kegiatan adalah meningkatkan pemahaman siswa mengenai peran, tanggung jawab, dan peluang karir apoteker. Metode kegiatan menggunakan pendekatan kuantitatif dengan desain one group pre-test post-test. Kegiatan diawali dengan pre-test untuk mengukur pengetahuan awal peserta, dilanjutkan dengan sesi edukasi interaktif menggunakan media proyektor, dan diakhiri dengan post-test untuk menilai peningkatan pemahaman. Data dianalisis menggunakan uji normalitas dan Wilcoxon Signed Rank Test. Hasil menunjukkan adanya peningkatan signifikan antara nilai pre-test dan post-test, menandakan bahwa kegiatan edukasi berpengaruh positif terhadap peningkatan pengetahuan siswa tentang profesi apoteker. Kesimpulannya, kegiatan ini berhasil meningkatkan pemahaman dan minat siswa terhadap profesi apoteker serta diharapkan dapat mendorong mereka untuk melanjutkan pendidikan ke jenjang profesi, guna membantu mengatasi kekurangan tenaga apoteker di Indonesia.
Ethanolic extract of Parkia speciosa Hassk leaves innovation of gastroretentive tablet: standardization and optimization Nurfitriyana, Nurfitriyana; Fitriya, Fitriya; Fithri, Najma Annuria; Putri, Dwi Kurnia; Lestari, Siti Marwah; Waluyo, Dyah Ayuwati; Syarif, Hardiyanti
JURNAL ILMU KEFARMASIAN INDONESIA Vol. 23 No. 2 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i2.1461

Abstract

Parkia speciosa ethanol leaves extract contains flavonoid, tannin, and terpen as ulcus peptic remedy. These compounds exhibit limited activity in the stomach due to the short gastric residence time following oral administration. The formulation of gastroretentive tablets can overcome this limitation. This research aims to control the prolonged release of drugs in the stomach to increase bioavailability and characterize the ethanol leaves extract. Extraction was carried out by maceration using ethanol, followed by standardization based on specific and non-specific parameters extract. Gastroretentive tablet was formulated with combination of HPMC-K4M and chitosan using factorial design 22. Effects of compositional factors and their interactions on gastroretentive tablet was observed on hardness, friability, floating lag/duration time, swelling index, and mucoadhesive time. Results standardization extract showed that extract met the required criteria for both specific parameters (organoleptic properties and phytochemical screening) and non-specific parameters (moisture content, loss on drying, water/ethanol-soluble extract content). Based on with DX®10 analysis, the optimum formulation was achieved with 20.25% of HPMC-K4M and 10.26% of chitosan. The analysis of the optimum formulation characteristics was as follows: friability (0.22%), hardness (29.53 N), mucoadhesive time (22.86 hours), floating lag/duration time (27.54 minutes; 12 hours), and swelling index (312.82%). Result revealed that gastroretentive tablets formulated with ethanol extract of Parkia speciosa leaves improve gastric residence duration and promote better bioavailability.