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All Journal Pharmacon Acta Pharmaciae Indonesia : Acta Pharm Indo JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Jurnal Kesehatan Medika Saintika Majalah Farmaseutik JSFK (Jurnal Sains Farmasi & Klinis) PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat JPP Jurnal Kesehatan Poltekkes Palembang Jurnal Ilmu Kesehatan Jurnal Ners Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat MAHESA : Malahayati Health Student Journal Indonesian Community Journal Abdi Geomedisains Jurnal Farmasi Sains dan Praktis Prosiding University Research Colloquium Journal of Pharmaceutical and Sciences. Journal of Community Empowerment
Cholisoh, Zakky
Fakultas Farmasi, Universitas Muhammadiyah Surakarta
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Assessment of Potentially Inappropriate Medication (PIMs) in Older Adult Patients at the Geriatric Polyclinic of a General Hospital in Central Java Cholisoh, Zakky; Riswanto, Muhammad Imam
Jurnal Ilmu Kesehatan Vol 11 No 2 (2023): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30650/jik.v11i2.3874

Abstract

One of the most critical issues affecting older adults is the increasing use of potentially inappropriate medication (PIMs). The use of PIMs is associated with drug-related problems, as well as undesirable drug effects. This study aimed to assess the prevalence of potentially inappropriate medication and the most commonly prescribed PIMs category in older adults. This research method is observational with a cross-sectional design. Drugs were analyzed using the 2019 Beers criteria compiled by The American Geriatrics Society (AGS), classifying PIMs into five categories. The inclusion criteria in this study were patients aged ≥65 years, using at least one drug, with a duration of drug use of at least one month, and analyzing this research data descriptively. The results showed that out of 134 prescriptions consisting of 773 drug items, 95 drug items were potentially inappropriate for use in older adults. The prevalence of PIMs was 12%, and if classified by category, then partly in order, inappropriate medication included category 1 (8.2%); category 2 (0.6%); category 3 (2.8%); category 4 (0.3%); category 5 (0.1%). The most common drugs included in category 1 PIMs criteria were proton pump inhibitors (PPIs), namely lansoprazole and omeprazole. Conclusion: In this study, the prevalence of potentially inappropriate Medication in older adults was 95 drug items (12%), and the more commonly prescribed category of PIMs is category one drugs and should avoid category one drugs in older adults.
Pengetahuan, Sikap, dan Perilaku Warga Negara Indonesia di Seoul Korea Selatan terhadap Penggunaan Obat Mandiri Karuniawati, Hidayah; Wikantyasning, Erindyah R.; Sukmawati, Anita; Cholisoh, Zakky; Nurwaini, Setyo; Swandari, Mika Tri Kumala; Farida, Rahayu; Rajali, Ahmad
Prosiding University Research Colloquium Proceeding of The 20th University Research Colloquium 2025: Bidang Pengabdian Masyarakat
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Prevalensi penggunaan obat mandiri di masyarakat cukup tinggi. Penggunaan obat secara mandiri yang tidak rasional dapat menyebabkan tujuan terapi tidak tercapai, bahkan dapat membahayakan pasien. Pengabdian ini bertujuan untuk mengetahui pengetahuan, sikap, dan perilaku warga negara Indonesia di Seoul Korea Selatan terhadap penggunaan obat secara mandiri. Kegiatan dilakukan di masjid Ansan Seoul Korea Selatan. Kegiatan inti berupa penyuluhan kepada warga Indonesia yang berada di Seoul terkait dengan penggunaan obat mandiri yang rasional yang meliputi bagaimana cara mendapatkan obat, menggunakan, menyimpan, dan membuang obat yang tidak dipakai. Meskipun 37 peserta hadir pada kegiatan ini, tetapi 14 peserta mengisi kuesioner. Mayoritas peserta (71,4%) adalah laki-laki, 64,3% umur 25-30 tahun, dan 50% pendidikan terakhir Sekolah Menengah Atas (SMA). Rata-rata pengetahuan responden terkait dengan pengobatan mandiri adalah 63,6% sedangkan sikap 72,9%. Pengetahuan, sikap, dan perilaku yang belum sesuai adalah cara mendapatkan obat (logo obat), cara minum obat, cara penyimpanan, dan cara membuang obat. Perlu edukasi farmasis untuk meningkatkan pengetahuan, sikap dan perilaku masyarakat dalam menggunakan obat mandiri secara rasional.
Pasien Kanker Payudara yang Menerima Terapi Tamoxifen di Dua Rumah Sakit Swasta di Jawa Tengah: Profil Sosiodemografi, Klinis, dan Pengobatan Setiawardani, Maria Fitri; Cholisoh, Zakky; Hapsari, Pramudita Mila
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 4 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i4.1114

Abstract

Breast cancer is one of the most common types of cancer, including in Central Java Province, Indonesia, which reports a high incidence. The number of cases continues to increase, likely due to low public awareness of breast self-examination (BSE), limited health education, and a lack of motivation to undergo regular check-ups. One of the main treatment options is hormonal therapy, with Tamoxifen being the most widely used drug. To date, there is limited data on the sociodemographic and clinical characteristics among breast cancer patients who use Tamoxifen in Central Java. This information is essential for improving patient care and treatment strategies. This study aimed to describe the sociodemographic and clinical characteristics of breast cancer patients who received Tamoxifen at two private hospitals in Central Java. The results showed that most patients were under 50 years old (66%), had a low level of education (65.2%), and were employed (34.8%). Clinically, most patients were in advanced stages (56.5%), had no comorbidities (89.7%), and were not taking other medications (85%). These findings provide an initial overview of the profile of breast cancer patients using tamoxifen at two private hospitals in Central Java. However, these results cannot be generalized to the entire Central Java region due to the limitations of the study locations. Further studies with a broader scope are needed to obtain more representative data.
Drug Related Problems (DRPs) pada Pasien Mata Rawat Inap: Kajian Potong Lintang Retrospektif selama Dua Tahun Utaminingsih, Esthi; Oktasari, Solikhah Rosvita; Cholisoh, Zakky
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 4 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i4.1123

Abstract

Drug-related problems (DRPs) in ophthalmic inpatients may compromise the effectiveness and safety of therapy. This study aimed to identify the characteristics of DRPs among inpatients with eye diseases at Hospital X Tangerang during September 2022–August 2024. A retrospective cross-sectional design was applied, involving 178 patients who met the inclusion criteria. DRPs were identified using the Pharmaceutical Care Network Europe (PCNE) classification version 9.1 through review of prescriptions, clinical data, and medication records. Descriptive analysis were used to determine the DRP occurrence. Results showed that most patients were aged 18–60 years (71.9%), female (55.1%), without comorbidities (82.0%), and received an average of 5 medications during hospitalization. Four DRP cases (2.2%) were identified, consisting of one case of treatment effectiveness (P1.2) 25% and three cases of drug safety problems (P2.1) 75%. The main causes were contraindicated drug use despite guideline adherence (C1.2) 50%, inappropriate drug combinations (C1.4) 25%, and patient non-adherence (C7.1) 25%. The low DRP incidence was likely related to the short hospitalization duration and the predominance of topical therapy with minimal systemic exposure. These findings highlight the important role of clinical pharmacists in therapy monitoring to prevent DRPs in ophthalmic inpatients.
Edukasi Hipertensi dan Pemberian Informasi Obat di Kampung Biru, Banjarmasin, Indonesia: Hypertension Education and Provision of Drug Information in Kampung Biru Banjarmasin, Indonesia Miranti, Rizka Mulya; Syah, Dhafina Salsabila; Cholisoh, Zakky; Setiawan, Abdul Aziz; Fauzia, Husna
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 10 No. 10 (2025): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v10i10.10232

Abstract

Hypertension poses a serious health challenge in South Kalimantan (prevalence: 30.4%), with low treatment adherence stemming from limited public understanding. This community service initiative aimed to enhance hypertension literacy and medication adherence through education and Drug Information Provision (PIO) in Kampung Biru, Banjarmasin. Methods included health screenings, physician consultations, disease-specific education, drug dispensing with PIO by pharmacists, and knowledge evaluation (pre-test/post-test). Among 58 participants (47 female, 11 male; aged 21–73 years), 25 were diagnosed with hypertension. At the same time, 35 participants showed improved knowledge (average score increase: 0.88 points), 11 experienced declines due to age-related factors and fatigue. Satisfaction surveys indicated 98.27% approval. The program effectively raised community awareness and warrants sustainable implementation with more inclusive approaches.
Kualitas Penulisan Resep untuk Pasien Pediatri di Rumah Sakit Surakarta Cholisoh, Zakky; Damayanti, Adelina; Sari, Dwi Novita
Prosiding University Research Colloquium Proceeding of The 10th University Research Colloquium 2019: Bidang MIPA dan Kesehatan
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Resep adalah proses transaksi dalam terapi yang penting antara dokter, apoteker, dan pasien. Resep yang berkualitas baik adalah faktor yang penting untuk meminimalkan kesalahan dalam pelayanan obat sehingga resep yang baik harus sesuai dengan pedoman penulisan resep untuk menjamin efektifitas dan keamanan pengobatan. Penelitian ini dilakukan untuk menganalisis kualitas penulisan resep untuk pasien anak di instalasi rawat jalan rumah sakit di Surakarta. Penelitian ini merupakan penelitian deskriptif cross-sectional yang dilakukan di dua rumah sakit. Sebanyak 368 resep untuk pasien pediatrik yang dikumpulkan di bulan Februari 2017 dari instalasi rawat jalan di rumah sakit dianalisis. Ketidaklengkapan penulisan berat badan (33,15%), usia (2,98%) dan jenis kelamin pasien (7,34%) teridentifikasi, padahal informasi tersebut merupakan hal tentang pasien yang penting untuk diketahui. Sebanyak 110 (29,89%) resep juga tidak mempunyai informasi kekuatan konsentrasi obat dalam sediaan. Dua ratus lima puluh tujuh resep (69,83%) tidak mencantumkan data nomer surat ijin praktek dokter dan 33 (8,97%) resep tidak mempunyai paraf dokter. Kualitas peresepan di instalasi rawat jalan masih belum memuaskan karena kurangnya informasi yang penting untuk sebuah resep yang berkualitas. Untuk meningkatkan kualitas dalam penulisan resep, kami menyarankan agar rumah sakit menyediakan formulir resep standar yang berisi informasi yang diperlukan untuk mengidentifikasi data pasien dan dokter.
Pengaruh Pemberian Edukasi oleh Apoteker terhadap Peningkatan Pengetahuan Masyarakat tentang Penatalaksanaan Nyeri pada Geriatri Cholisoh, Zakky; Azmi, Rizki Nur; Malik, Irhamadi
Prosiding University Research Colloquium Proceeding of The 11th University Research Colloquium 2020: Bidang MIPA dan Kesehatan
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Usia geriatri akan merubah kondisi fisik dan profil farmakokinetik farmakodinamik. Meningkatnya sarana kesehatan (klinik dan apotek) yang terdapat di Kabupaten Sukoharjo berdampak pada penggunaan obat masyarakat yang secara bebas melakukan upaya untuk memelihara dan meningkatkan kesehatan sendiri (swamedikasi). Swamedikasi tanpa dasar pengetahuan yang tepat dapat meningkatkan kemungkinan terjadinya medication error. Intervensi edukasi obat oleh Apotekerterbukti dapat menurunkn angka kejadian medication error. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh sesi edukasi oleh apoteker terhadap pengetahuan masyarakat Dusun Karangtengah Ngadirejo Kartasura Sukoharjo tentang penatalaksanaan nyeri pada penyakit otot dan tulang dengan obat dan tanpa obat serta bagaimana cara memilih obat penghilang rasa nyeri yang aman. Penelitian dilakukan dengan cara memberikan intervensi edukasi kepada respoden. Evaluasi tertulis dengan memberikan kuesioner dilakukan sebelum dan sesudah intervensi. Kuesioner berisi pertanyaan tertutup tentang penyebab gout, rematik, dan osteoarthritis, perbedaan antara ketiganya; serta penatalaksanaan nyeri karena penyakit otot dan tulang. Analisis data dilakukan dengan membandingkan skor pengetahuan sebelum dan sesudah intervensi dengan uji t berpasangan. Hasil penelitian menunjukkan adanya peningkatan pengetahuan masyarakat tentang penyakit rematik dan penatalaksanaan nyeri sebelum dan sesudah edukasi secara signifikan (uji t berpasangan p< 0,001) dengan rata-rata nilai pengetahuan sebelum penyuluhan adalah 55,0±23,1 dan sesudah penyuluhan adalah 82,0±15,4. Berdasarkan hasil penelitian tersebut terbukti bahwa sesi edukasi oleh apoteker dapat meningkatkan pengetahuan masyarakat tentang penatalaksanaan nyeri secara signifikan. Hal ini diharapkan akan memunculkan kesadaran yang dapat merubah tingkah laku atau pola pikir seseorang agar dapat memperoleh obat yang efektif dan aman serta dapat menggunakan obat nyeri dengan baik dan benar.
PROFIL KEPATUHAN PENGGUNAAN OBAT ANTIRETROVIRAL PADA PASIEN HIV/AIDS DI SEBUAH RUMAH SAKIT UMUM JAWA TENGAH PADA TAHUN 2022 Wahyudi, Afiv; Cholisoh, Zakky
Jurnal Kesehatan Medika Saintika Vol 14, No 2 (2023): Desember 2023
Publisher : Stikes Syedza Saintika Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30633/jkms.v14i2.2090

Abstract

Jumlah AIDS di Jawa Tengah merupakan peringkat 3 terbanyak dari seluruh provinsi di Indonesia. Terapi yang digunakan untuk mencegah AIDS pada pasien HIV yaitu dengan pemberian ARV. Kepatuhan terapi ARV (antiretroviral) sangat penting karena berkaitan erat dengan Parameter keberhasilan terapi dan tingkat penularan dari penyakit HIV. Penelitian ini bertujuan untuk mengidentifikasi profil kepatuhan penggunaan obat antiretroviral pada pasien HIV/AIDS yang menjalani rawat jalan di sebuah rumah sakit umum Jawa Tengah. Jenis penelitian ini adalah cross-sectional dengan pengambilan data secara retrospektif dari rekam medis pasien yang memenuhi kriteria inklusi yaitu pasien dari pasien di sebuah rumah sakit Jawa Tengah yang nama pasien ditandai dengan inisial untuk menjaga kerahasiaan pasien. Ukuran kepatuhan dihitung dengan medication possession ratio (MPR). Untuk mengetahui pengaruh variabel lain (usia, jenis kelamin, pekerjaan, status pernikahan, pendidikan terakhir, dan regimen awal ARV) terhadap kepatuhan, dilakukan uji bivariat. Dari 96 pasien, jumlah pasien yang patuh sebesar 64,58% dengan sebagian besar regimen TDF+3TC+EFV 55,21%. Setelah dilakukan uji bivariat, variabel usia, jenis kelamin, pekerjaan, status pernikahan, pendidikan terakhir, dan regimen awal ARV tidak berpengaruh terhadap tingkat kepatuhan pasien.
Demographic, Clinical, and Antiretroviral Regiment Treatment Characteristics of HIV/AIDS Patients at the Regional General Hospital of Central Papua Mar’ah, Siti Sitatul; Ichsan, Burhannudin; Cholisoh, Zakky
Pharmacon: Jurnal Farmasi Indonesia Vol 20, No 2 (2023)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v20i2.23300

Abstract

The incidence of HIV infections in Papua is currently on the rise, primarily due to restricted access to antiretroviral treatment and insufficient support and care. Additionally, there is a lack of awareness among residents in rural or mountainous areas about HIV/AIDS infection, as provided by healthcare professionals. Until now, research data have been scarce on the demographic characteristics, clinical features, and treatment approaches for HIV/AIDS patients in the interior regions of Papua. This data is crucial for devising strategies aimed at enhancing healthcare services for individuals affected by HIV/AIDS.Consequently, this study endeavors to gain insights into the demographic characteristics, clinical features, and treatment modalities for HIV/AIDS patients at the Regional General Hospital of the Central Papua Region. It employs an observational descriptive approach, utilizing medical records of HIV/AIDS patients who visited the Central Papua Regional Government Hospital in June 2023. The findings indicate that, based on demographic data, the majority of patients were, on average, ≤25 years old (60.8%), male (52.5%), married (56.7%), and the highest number of HIV/AIDS cases were among secondary education graduates (40.8%). The majority were employed (67.5%) with incomes below the minimum wage threshold (69.2%). All heterosexual patients exhibited behavioral risk factors, and 4.2% had comorbidities such as hypertension. Tuberculosis was the most common opportunistic infection (17.5%). The highest proportion of individuals with HIV/AIDS were in stage II (66.7%). The predominant antiretroviral treatment regimen was a fixed-dose combination (FDC) containing Tenofovir 300mg, Lamivudine 300mg, and Efavirenz 600mg. The duration of use of ARV therapy in people with HIV / AIDS is at most 1 month. 
Gambaran Adverse Drug Reactions (Adrs) Pada Pasien Kanker Payudara yang Mendapatkan Adjuvant Endocrine Therapy (Aet) Tamoxifen dan Faktor-Faktor yang Mempengaruhinya di Rs Swasta Semarang Tahun 2023 Kusumastuti, Maria Siska Triyuniar; Cholisoh, Zakky
Jurnal Ners Vol. 8 No. 1 (2024): APRIL 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v8i1.19330

Abstract

The use of adjuvant endocrine therapy (AET) tamoxifen in the treatment of breast cancer has been associated with adverse drug reactions (ADRs). This study aims to assess the picture of ADRs in breast cancer patients receiving Tamoxifen Adjuvant Endocrine Therapy (AET) and the factors that influence it in Semarang private hospitals. This study was conducted with a cross-sectional design that was analyzed quantitatively and the sampling technique was carried out by purposive sampling. The inclusion criteria are adult breast cancer patients who receive Adjuvant Endocrine Therapy (AET) tamoxifen at least in 1 month, patients are willing to be respondents to fill out questionnaires by signing informed consent. Evaluation of the incidence of ADRs identified by the pharmacist. A total of 87 respondents experienced 18 types of ADRs. The three most common ADR events experienced by patients in the last 7 days were hormonal reactions to painful breasts (25.68%), hot or warm sensations in the upper body (chest, neck, face) (13.51%), vaginal dryness (10.14%). There is an incidence of ADRs in breast cancer patients receiving Adjuvant Endocrine Therapy (AET) tamoxifen. The three most common ADR events experienced by patients in the last 7 days were hormonal reactions to painful breasts (25.68%), hot or warm sensations in the upper body (chest, neck, face) (13.51%), vaginal dryness (10.14%). It is known that age, stage, and consumption of other drugs are not significantly associated with the incidence of ADR.
Co-Authors Adelina Damayanti Amanda Wahyu Kurniawan Ambar Yunita Ambar Yunita Nugraheni Anita Sukmawati Audi Tahta Aurellia Azmi, Rizki Nur Brainandiva Ade Fitria Burhannudin Ichsan Cahya Rahma Utami Damayanti, Adelina Dedi Hanwar Dian Oktianti Dwi Novita Sari Endang Setyaningsih Erindyah Retno Wikantyasning Farida, Rahayu Gita Ayu Pradina Hapsari, Pramudita Mila Hekmah, Laila Nur Heppy Purbasari Hidayah Karuniawati Hidayah, Azzahra Zulfa Nur Husna Fauzia Ika Trisharyanti Dian Kusumowati Irhamadi Malik Khoirunnisa Khoirunnisa Kusumastuti, Maria Siska Triyuniar Kusumawardani, Mia Laila Nur Hekmah Larasati, Arindra Luluk Ria Rakhma Malik, Irhamadi Mar’ah, Siti Sitatul Mika Tri Kumala Swandari, Mika Tri Kumala Muhammad Faqih Muhammad Ikhsan Al Af Ghani Oktasari, Solikhah Rosvita Pradina, Gita Ayu Pramudita Mila Hapsari Putri, Citra Agustin Ananda Putri, Nabilla Andasari Rajali, Ahmad Ramadhani, Renita Nur Ramdani, Tasya Eka Refsya Azanti Putri Reiza, Zenita Rima Munawaroh Riswanto, Muhammad Imam Rizka Mulya Miranti Rizki Nur Azmi Rohmah, Siti Alfiatur Rosi Hayyu Anjani Rukmini, Aulia Sally Astya Utami Sania Nayasari Khoirunnisa Sari, Dwi Novita Seftiyanti , Nirma Setiaji, Muh Maskur Setiawan, Abdul Aziz Setiawardani, Maria Fitri Setyo Nurwaini Siti Alfiatur Rohmah Suryaman, Sulistia Syah, Dhafina Salsabila Tanti Azizah Tanti Azizah Utami, Sally Astya Utaminingsih, Esthi Wahyu Utami, Wahyu Wahyudi, Afiv Wikantyasning, Erindyah R. Yuka Aulia Rahma Zaenab Zaenab Zaenab Zulfa, Farah Qanitha Zurroh, Al Hajar Fuadatus