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All Journal Jurnal Analis Farmasi Jurnal Kesehatan Tambusai Jurnal Buana Farma JAF (Jurnal Analis Farmasi) JIFI (Jurnal Ilmiah Farmasi Imelda) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE) Jurnal Riset Rumpun Ilmu Kesehatan (JURRIKES) Duta Pharma Journal Jurnal Kesehatan Amanah Proceeding of International Conference Health, Science And Technology (ICOHETECH) Indonesian Research Journal on Education Eduvest - Journal of Universal Studies Prosiding Seminar Informasi Kesehatan Nasional International Journal of Health, Engineering and Technology Jurnal Akademik Pengabdian Masyarakat Journal of Innovative and Creativity Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Jurnal Padamu Negeri Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Bagas Ardiyantoro
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INDUKSI DIGITAL MARKETING PADA UKM HEWAN MENCIT DALAM MENINGKATAN PENJUALAN Triana Triana; Bagas Ardiyantoro; Intan Oktaviani
Jurnal Padamu Negeri Vol. 2 No. 4 (2025): Oktober : Jurnal Padamu Negeri (JPN)
Publisher : CV. Denasya Smart Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69714/zkrh9q73

Abstract

The development of digital technology provides great opportunities for Small and Medium Enterprises (SMEs) to improve efficiency and expand their marketing reach. The SME providing laboratory test mice in Surakarta still faces limitations in marketing processes, customer data management, and product distribution, which are mostly carried out manually. This Student Creativity Program (PKM) activity aims to implement digital marketing transformation through the development and application of the Digital Laboratory Test Mice Application of Surakarta as an integrated platform for promotion, ordering, and customer data management. The implementation methods include partner needs analysis, web and mobile-based system design, user training, and effectiveness evaluation. The results show significant improvements in transaction efficiency, ease of product information access, and market reach expansion for the SME. Through the application’s implementation, the partner SME is able to adapt to digital trends, strengthen competitiveness, and enhance service professionalism in providing laboratory test mice.
Formulasi dan Uji Aktivitas Antioksidan Face Toner Ekstrak Etanol Daun Yakon (Smallanthus sonchifolius) Menggunakan Metode DPPH Fika Riyanti; Bagas Ardiyantoro; Siwi Hastuti
Journal of Innovative and Creativity Vol. 6 No. 1 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

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Abstract

Excessive exposure to sunlight can cause the formation of free radicals that can damage skin tissue, thus requiring natural antioxidants. The use of natural ingredients as a source of antioxidants in the form of topical preparations is a potential alternative. This study aims to formulate ethanol extract of yakon leaves (Smallanthus sonchifolius) into a face toner formulation and evaluate its physical quality, antioxidant activity, and to determine the optimal concentration of the face toner formulation that can inhibit free radicals. Extraction was carried out using the maceration method with 70% ethanol, then formulated into face toner with different concentrations, namely 1%, 2%, and 3%. After that, physical quality evaluation was carried out in the form of organoleptic tests, pH tests, homogeneity tests, and viscosity tests. Antioxidant activity was tested using the DPPH method and measured using UV-Vis spectroscopy at a wavelength of 520 nm. The results showed that all formulas met the physical quality test standards and had antioxidant activity at concentrations of 1%, 2%, and 3% with IC50 values of 95.91, 93.58, and 91.70, respectively, all of which were classified as strong. while the negative control formula without extract had a value of 167 (weak category), and the positive control quercetin had a value of 9.95 (very strong category).
Optimasi Nilai Sun Protection Factor (SPF) Ekstrak Daun Bayam Hijau (Amaranthus hybridus L.) Berdasarkan Variasi Pelarut Etanol 70% dan Aseton dengan Metode Spektrofotometri UV-Vis Tasya Aurelia; Rahmat Hidayat; Bagas Ardiyantoro
Journal of Innovative and Creativity Vol. 6 No. 1 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v6i1.8293

Abstract

ABSTRACT Indonesia has high levels of ultraviolet (UV) exposure, which poses a risk of skin health problems. The use of sunscreen is necessary as a protective measure, but synthetic sunscreens can cause side effects, so natural alternatives are needed. Green amaranth leaves (Amaranthus hybridus L.) contain flavonoids that have the potential to absorb UV rays. This study aims to evaluate the sunscreen activity of green amaranth leaf extract using 70% ethanol and acetone solvents, determine the optimum Sun Protection Factor (SPF) value, and identify the most effective and efficient solvent. Extraction was performed using the maceration method, then the sunscreen activity was tested using UV-Vis spectrophotometry at a wavelength of 290–320 nm with concentration variations of 40, 60, 80, 100, and 120 ppm. The results showed that both extracts had sunscreen activity. The optimum SPF value was obtained at a concentration of 120 ppm, namely 70% ethanol extract 11,45 (maximum protection) and acetone extract 19,11 (ultra protection). Acetone was the most effective and efficient solvent in extracting UV-absorbing compounds. Keywords: 70% Ethanol, Acetone, Green Spinach Leaves (Amaranthus hybridus L.), SPF, Sunscreen
Studi In-Vitro Antikolesterol dari Fraksi Etil Asetat Daun Buni Antidesma bunius L. Spreng Thoha Irfan Darojat; Danang Raharjo; Bagas Ardiyantoro
Jurnal Kesehatan Amanah Vol. 10 No. 1 (2026): Mei: Jurnal Kesehatan Amanah
Publisher : Universitas Muhammadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jka.v10i1.1053

Abstract

Hypercholesterolemia, defined as elevated levels of cholesterol in the bloodstream, is widely recognized as a major risk factor for cardiovascular diseases, including atherosclerosis and coronary heart disease. Antioxidants play an important role in preventing oxidative damage by neutralizing free radicals through electron donation, thereby helping to reduce lipid peroxidation associated with high cholesterol levels. This study aims to evaluate the cholesterol-lowering activity of the ethyl acetate fraction of buni leaves (Antidesma bunius) through laboratory experimentation. The leaves were extracted using the maceration method with 96% ethanol, followed by fractionation with ethyl acetate to obtain the targeted fraction. The in vitro anticholesterol activity was determined using the Liebermann–Burchard method and measured by UV-Vis spectrophotometry. Data analysis was performed using linear regression to calculate the IC₅₀ value. The results demonstrated that the ethyl acetate fraction exhibited very strong cholesterol-lowering activity, with an IC₅₀ value of 1,659 ppm/µg/mL, indicating promising potential as a natural antihypercholesterolemic agent.
Deteksi dan Kuantifikasi Hidrokuinon pada Sampel Night Cream di Kecamatan X Sukoharjo Retno Kurnia Dewi; Danang Raharjo; Bagas Ardiyantoro
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 5 No. 1 (2026): April: Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v5i1.8503

Abstract

Hydroquinone is a skin lightening agent that effectively inhibits melanogenesis, but its use in cosmetics is restricted due to the potential for serious side effects. Although banned in over-the-counter cosmetics, hydroquinone is still found in unregistered night cream products. This study aims to detect the presence, determine the levels of hydroquinone, and evaluate its safety risks in night cream products sold in District X, Sukoharjo Regency. The study was conducted experimentally in a laboratory using a purposive sampling technique on 15 night cream samples consisting of 8 BPOM-registered products and 7 non-BPOM products. Qualitative analysis was carried out using FeCl₃, Benedict's, and o-phenanthroline color reaction tests, while quantitative analysis used the HPLC method with a C18 column and a UV-Vis detector at a wavelength of 280 nm. The results showed that all BPOM-registered samples did not contain hydroquinone, while several non-BPOM samples were detected to contain hydroquinone at levels ranging from 0.0688%–0.2043%. These findings indicate a higher safety risk in non-BPOM products. The implications of this research emphasize the importance of strengthening regulatory oversight and increasing public literacy in choosing safe and legal cosmetic products.
Memory Activity Test Of Ethanol Extract Of Oil Palm Leaves (Elaeis Guineensis Jacq.) On White Mice (Mus Musculus) With Radial Arm Maze Method Nadia; Bagas Ardiyantoro; Septian Maulid Wicahyo
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.607

Abstract

Memory loss is a cognitive disorder in which oxidative stress is one of the main contributing factors. Palm leaves oil (Elaeis guineensis Jacq.) contains flavonoids and antioxidants that are believed to improve memory. This study aims to determine whether oil palm leaf extract can improve memory activity in mice and determine the most effective dosage. This study was a pure experimental study with 25 mice divided into five groups, namely negative control (CMC Na 1%), positive control (Ginkgo biloba), and treatment groups with ethanol extracts of oil palm leaves at doses of 100 mg/kgBW, 200 mg/kgBW, and 300 mg/kgBW. The mice were induced with 10% alcohol and then given treatment for 7 days. Memory activity was tested using the Radial Arm Maze method, with parameters measured including latency time and error rate. The data obtained were then analyzed using SPSS, including normality and homogeneity tests, Anova, and followed by the Tukey test. The results showed that doses of palm leaf extract (Elaeis guineensis jacq.) of 100 mg/kgBW, 200 mg/kgBW, and 300 mg/kgBW had an effect on the memory of mice. The effective dose for improving memory in the T1-T2 latency time difference was 200 mg/kgBW and 300 mg/kgBW with a P value > 0.05, which was not significantly different from the positive control, and the T1-T2 error rate difference was 100 mg/kgBW, 200 mg/kgBW, and 300 mg/kgBW, with a P value > 0.05, showing no significant difference from the positive controls. This proves that oil palm leaf extract can enhance memory activity in mice.
Co-Authors Abdul Wahab Sabrina, Azimah Alya Atla Lidya Anita Dwi Septiarini Anita dwi setiarini Anna Fitriawati apriliyanti, laela intan arniwati mat daud, Noor Danang Raharjo Dwi Nurul Khotimah Dwi S, Anita Fachry Abda El Rahman Fadila, Vera Nurhidayatul Fika Riyanti Fitriana, Mona Haikal Zanki Hery Widijanto Intan Oktaviani Iqbal Sirajudin Maulidinawan Jayak Pratama, Kharisma Karim Karim, Karim Listyani, Tiara Ajeng Lutfiyanti, Niken Luthfiyanti, Niken Merari P, Ason Meyliawati, Ika Muhamad Farid Nurohman Krisnadi Nadia Nafiah, Azidatun Netty Dea Sosiantini Ningrum, Della Puspita Permata, Bangkit Riska Putri, Anisa Fadilah Kumala Putri, Fera Adila Rahmad Adji, Alenda Rahmat Hidayat Rahmat Hidayat Rahmatillah, Annie Retno Kurnia Dewi Rohmana, Vivin Marwiyati Salsabila Khoerunniyssa Sari, Silvia Mega Kusuma Septian Maulid Wicahyo Siwi Hastuti Sugeng Santoso Suharjaya, Feby Nuranawati Tasya Aurelia Thoha Irfan Darojat Triana Triana uswatun hasanah, alfiana Wali Jati, Ilham Wardani, Tatiana Siska Wiwin Novitasari