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All Journal Journal of Experimental and Clinical Pharmacy (JECP) Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Journal of Community and Clinical Pharmacy Journal of Pharmacology and Natural Products
Manno, Mohamad Reski
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Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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FAKTOR PENGHAMBAT PENGOBATAN PASIEN TUBERKULOSIS PARU DI PUSKESMAS KECAMATAN TAPA KABUPATEN BONE BOLANGO: Tuberkulosis merupakan penyakit menular yang disebabkan oleh infeksi bakteri Mycobacterium tuberculos. kelompok Mycobacterium yaitu Mycobacterium tuberculosis. Terdapat beberapa spesies Mycobacterium, antara lain: M. tuberculosis, M. africanum, M. bovis, M. leprae. Tujuan penelitian ini untuk mengetahui apa saja factor yang menjadi Penghambat Pengobatan pasien Tuberkulosis Paru di Puskesmas Rasdianah, Nur; Taupik, Muhammad; Djuarno, Endah Nurrohwintah; Hutuba, Ariani; Manno, Mohamad Reski; molote, kasibee molote
Journal of Community and Clinical Pharmacy Vol. 2 No. 3 (2025): Volume 2, Number 3, 2025
Publisher : Jurnal Literasi Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70075/jccp.v2i3.215

Abstract

Tuberculosis is an infectious disease caused by infection with the bacteria Mycobacterium tuberculos. The Mycobacterium group is Mycobacterium tuberculosis. There are several species of Mycobacterium, including: M. tuberculosis, M. africanum, M. bovis, M. leprae. The purpose of this study was to determine what factors inhibit the treatment of pulmonary tuberculosis patients at the Tapa District Health Center, Bone Bolango Regency. This research method is qualitative descriptive with Purposive Sampling sampling with inclusion criteria. Data analysis uses data reduction, data presentation, drawing conclusions/verification. The results of the study based on the experience of consuming medication, patients have several symptoms that can be inhibiting factors for treatment, namely two patients with itching, five patients with nausea, two patients with body aches and two patients with poor appetite. As for the obstacles and barriers when consuming medication, there are five patients out of 15 patients who have obstacles, namely P1 feels hot, P2 feels pain when coughing, P3 feels vomiting, P4 feels chest pain, red urine and often thirsty, and P5 feels no appetite. And the drugs prescribed for all respondents are in accordance with the health services at the Tapa Community Health Center, which are very good.
Overview of Antipsychotic Use in Schizophrenia Patients at the East City Health Center in 2024 Tuloli, Teti Sutriyati; Makkulawu, Andi; Sumaga, Khairunnisa Alya; Madania, Madania; Manno, Mohamad Reski
Journal of Experimental and Clinical Pharmacy (JECP) Vol 5, No 2 (2025): August 2025
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v5i2.1388

Abstract

Schizophrenia is a severe mental disorder that affects individuals and greatly impacts their families and society, with symptoms like hallucinations, delusions, and emotional or thought disturbances that disrupt daily life and well-being. Treatment for schizophrenia usually involves a combination of antipsychotic drug therapy, psychotherapy, and social support. This study aims to determine the description of antipsychotic use, including the type of drug, rules of use, drug dosage, and duration of use in schizophrenia patients at the Kota Timur Health Center. This study used a descriptive observational research design with data collection using a retrospective method. The research data were obtained from secondary data in the form of medical record data from as many as 25 patients with mental illness. The data were processed with Excel and analyzed using SPSS version 26. The results showed that schizophrenia was predominantly suffered by male patients (56%), and more were in the age range of 34-46 years (as many as 48%). The most widely used antipsychotic drugs were a combination of typical and atypical, as many as 92%. The most frequently used type of drug is clozapine with a dose of 25 mg, and the rules of use are 2 x 1/2 as much as 46%. The longest duration of treatment is already in the maintenance phase, which is 96%. Additional drug trihexyphenidyl 2 mg (2 x 1) is used as much as 92%. The most widely used type of therapy is 3-combination therapy, namely Risperidone + THP + Clozapine, as much as 56%. This study was conducted at the East City Health Center, Gorontalo, which is one of the largest primary healthcare facilities in the region and manages a considerable number of schizophrenia patients with limited psychiatric resources. Therefore, the study setting provides important insights into the real-world use of antipsychotic medications in a community-based healthcare center.
UJI ANTIOKSIDAN EKSTRAK ETANOL 70% DAUN HULOTUA (Commelina Longifolia L) DENGAN METODE DPPH ( 2,2-difenil-1-pikrilhidrazil) MENGGUNAKAN SPEKTROFOTOMETRI UV-Vis Mustapa, Mohamad Adam; Suryadi, A. Mu'thi Andy; Makkulawu, Andi; Paneo, Mohamad Aprianto; Manno, Mohamad Reski; Ibrahim, Anwar
Journal of Pharmacology and Natural Products Vol. 2 No. 3 (2025): Volume 2, Nomor 3, Tahun 2025
Publisher : Jurnal Literasi Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70075/jpnp.v2i3.123

Abstract

Commelina Longifolia L merupakan tumbuhan yang berasal dari family yaitu Commeliaceae. Dimana tanaman ini memiliki senyawa yang dapat berpotensi sebagai antioksidan. Beberapa penelitian dengan family yang sama menunjukkan bahwa ekstrak Daun Hulotua mengandung senyawa fenolik dan flavonoid yang dapat berperan sebagai antioksidan. Penelitian ini bertujuan untuk mengetahui kandungan metabolit sekunder yang terdapat dalam daun hulotua serta mengetahui potensi ekstrak dari Daun Hulotua sebagai antioksidan. Metode penelitian ini menggunakan metode analisis kualitatif dan kuantitatif. Analisis kualitatif pada penelitian ini menggunakan metode skrining fitokimia dengan uji tabung/uji warna dan analisis Kromatografi Lapis Tipis menggunakan eluen Kloroform : n-Heksan : etil asetat dengan perbandingan (2:2:1). Analisis kuantitatif menggunakan spektrofotometri UV-Vis pada panjang gelombang 517 nm dengan pembanding Vitamin C. Hasil penelitian menunjukkan nilai antioksidan dari ekstrak metanol daun Hulotua (Commelina Longifolia L) memiliki nilai IC50 yaitu 41,73 µg/ml dan termasuk dalam kategori sangat kuat. Sedangkan pada Vitamin C memiliki nilai IC50 yaitu 65,59 µg/ml dan termasuk dalam kategori kuat.Berdasarkan Analisis data statistik Uji Independent t-test dimana (p-value<0,05) menunjukan terdapat perbedaan rata-rata yang signifikan antara kelompok perlakuan (pvalue<0,05).
Co-Authors A. Mu'thi Andy Suryadi Andy Suryadi, A. Mu'thi Antuli, Zikran Nazar Antuli ANWAR IBRAHIM, ANWAR Ariani H. Hutuba baruadi., siti_yustika. Dizky Ramadani Putri Papeo djuarno, endah nurrohwinta Djuarno, Endah Nurrohwintah Dr. Apt. Hamsidar Hasan S.Si.,M.Si Endah N. Djuwarno Endah Nurrohwinta Djuwarno Fatimah Azzahra Fika Nuzul Ramadhani Hunowu, Sri Yulian Hutuba, Ariani Julianti, Natasya Melly Kadir, Laksmyn Kaino, Ratni Madania Madania, Madania Mahdalena Sy Pakaya Makkulawu, Andi Maku, Diva Julyar Cahyani Mohamad Adam Mustapa Mohamad Aprianto Paneo Mohamad Aprianto Paneo molote, kasibee molote Muhammad Taupik Nur Rasdianah Puluhulawa, Lisa Efriani Rahmayani, Siti Farah Sumaga, Khairunnisa Alya Suryadi, A. Mu'thi Andy Suswanti Teti Sutriyati Tuloli Widy Susanti Abdulkadir Wiwit Zuriati Uno