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All Journal Jurnal Biologi Tropis Jurnal Abdi Insani Promotor: Jurnal Mahasiswa Kesehatan Masyarakat
Retnaningsih, Ekawaty
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Journal : Jurnal Biologi Tropis

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Resveratrol: A Potential Active Compound for Inflammatory Bowel Disease Saraswati, Ni Wayan Citra Ayu; Nugraha, Gede Rama Hardy; Retnaningsih, Ekawaty; Afifah, Fiza; Firdaus, Silmi; Mutia, Baiq Marceliya Anjani; Mukhlishah, Neneng Rachmalia Izzatul
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.7303

Abstract

Inflammatory Bowel Disease (IBD) is a chronic intestinal disorder consisting of Crohn’s Disease (CD) and Ulcerative Colitis (UC). The highest prevalence of IBD is found in Asia and the cases often occur in the 15-35 group of age. Conventional therapy options that are commonly used have some side effects that impact IBD patients. Therefore, it is necessary to look for new strategies in order to treat IBD regarding their effectiveness, affordability and achieving minimum side effects. Resveratrol, a natural non-flavonoid polyphenolic compound, is commonly found in grapes and various types of berries. It is known to potentially overcome inflammation in IBD through various mechanisms including acting as anti-inflammatory, antioxidant, immunomodulatory effects, and its ability to influence the gut microbiota. This study is aiming for explaining and reviewing further mainly on resveratrol’s extraction method and its mechanism of actions to improve IBD. The resources for this study are done by searching through PubMed, ProQuest, ScienceDirect, MDPI, and Google Scholar with keywords (Inflammatory Bowel Disease) AND (Resveratrol), ⁠(Incidence and Prevalence) of Inflammatory Bowel Disease across Asia, (Threat) AND (Therapy) AND (Inflammatory Bowel Disease), (Bioactive) AND (Therapy) AND (Inflammatory Bowel Disease), (Extraction) AND (Method) AND (Resveratrol), and (Pathophysiology) AND (Inflammatory Bowel Disease). Based on evidence found on resveratrol’s benefits, this compound is apparently promising to alternatively treat IBD, but still needs more research to support its effectiveness.
Co-Authors Abdiman, I Made Tobias Afifah, Fiza Amanullah, Mohammad Sany Rosafi Arhya Putra, Made Raditya Farras, Afif Firdaus, Silmi Ginuluh, Gintis Dhimar Hardyningrat, Baiq Inna Dwi Hayaza, Safira Said Hazaa, Saskia Safarinaa Ishlahi, Salsabila Dinda Nuril Kadarisma, Shofia Karlina, Fairuz Kirana, Devi Chandra Makbul, Ini Hidayat Metta Octora Mujahid, Sabila Izzatina Azmy Mukhlishah, Neneng Rachmalia Izzatul Mutia, Baiq Marceliya Anjani Nugraha, Gede Rama Hardy Nugraha, Kadek Nandita Putra, Rifky Sandya Rakadi Putra, Yusril Sani Riandika Putri, Atina Rizki Saraswati, Ni Wayan Citra Ayu Sesariana, Mayumi Agestia Sholihatin, Illiyani Siti Nurhaliza Syalsabila, Dara Pitra Yahya, Najla Aulia