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All Journal Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ Journal of Pharmaceutical and Medicinal Sciences Jurnal Mandala Pharmacon Indonesia Health Information : Jurnal Penelitian Journal of Experimental and Clinical Pharmacy (JECP) Jurnal Pengabdian Mandiri Pharmaceutical Reports Journal of Noncommunicable Diseases (JOND) jpki Jurnal Katalisator Sahabat Sosial: Jurnal Pengabdian Masyarakat International Journal of Health Sciences E-Amal: Jurnal Pengabdian Kepada Masyarakat Jurnal Sains dan Kesehatan
Utami, Yuri Pratiwi
Sekolah Tinggi Ilmu Farmasi Makassar
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Antioxidant Activity Of Leilem Leaf Extract Fractions Clerodendrum minahassae Teijsm. and Binn. Using The DPPH Method (2,2-Diphenyl-1-Picrylhydrazil) Imrawati, Imrawati; Utami, Yuri Pratiwi; Hardianto, Hardianto
International Journal of Health Sciences Vol. 1 No. 4 (2023): IJHS : International Journal of Health Sciences
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/ijhs.v1i4.220

Abstract

Clerodendrum minahassae Teijsm. and Binn plant is included in the Clerodendrum genus which contains chemicals such as alkaloids, flavonoids, phenols, tannins and steroids which have an important role in the development of medicine, including as antioxidants, anti-inflammatory, anti-diabetic and antibacterial. This study aims to determine the antioxidant activity of leilem leaf fractions using the DPPH method. Leilem leaves were extracted using the maceration method using 70% ethanol, then partitioned using the liquid-liquid extraction method using three different solvents, namely n-hexane, ethyl acetate and water. The fraction of the partition was then tested for antioxidant activity using the DPPH method and its absorbance was measured using a UV-VIS spectrophotometer with a wavelength of 515 nm. The research results showed that the n-hexane fraction had an IC50 value of 185.704 ppm, the ethyl acetate fraction had an IC50 value of 105.357 ppm and the water fraction had an IC50 value of 549.258 ppm with the IC50 value of the quarcetin comparison being 8.86 ppm. It can be concluded that the highest antioxidant activity is found in the ethyl acetate fraction, which is included in the moderate antioxidant category.
Co-Authors Abd Rasyid Abd. Halim Umar Abdul Halim Umar Abubakar Betan Afni, Fauza Ainun Jariah Ainun Jariah Ainun Jariah Amody, Zahira Aprilia Matelda Dwi Kristiyanti Arif Rachman Aripa, Lusyana Asril Asril Burhan Asril Burhan Astuti Amin Burhanuddin Taebe Dewi Sarwati Erianto, Fatricia Fadel Ahmad Haris Fadhilla Maryam Fadillah Maryam Fajriansyah Fajriansyah Fhahri Mubarak Fitri Andriani, Fitri Hamdayani L. A Hardianti Hardianti, Hardianti HARDIANTO - Herlina Rante Hilal, Achmad Humang, Rezki Ihsan Imrawati Imrawati Imrawati Imrawati Imrawati Imrawati, Imrawati Indah Kadullah Irmayanti Irmayanti, Irmayanti Khairuddin Khairuddin Khairuddin Khairuddin Lusianawati, Hayu Mangosa, Grace Pretty Marwati Marwati Mar’atun Jannah, Imrawati, Muzakkir Baitz, Massolo, Selpi Muh Azwar AR Mus, Suwahyuni Nasution, Ahmad Faisal Nur Aida Kubangun * Nurhedah, Nurhedah Pannyiwi, Rahmat Prima Astuti Handayani Rahmah Mustarin Rahman, Nur Fausia Rahmat, Rezqiqah Aulia Reny Syahruni Rohana Rohana Rosadika Fatimah Rosdiana Rosdiana S, St. Mujahida Sari, Lely Meriaya Sima, Yenny Sri Wahyuni Suminar, Saka Surya, Sara Suwahyuni Mus Wahyu Hendrarti Wahyuddin Wahyuddin Wahyuddin Zaenal Zaenal, Zaenal Zulfahmidah Zulfahmidah