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Universa Medicina
Published by Universitas Trisakti
ISSN : 19073062     EISSN : 24072230     DOI : -
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Universa Medicina (univ.med) is a four-monthly medical journal that publishes new research findings on a wide variety of topics of importance to biomedical science and clinical practice. Universa Medicina Online contains both the current issue and an online archive that can be accessed through browsing, advanced searching, or collections by disease or topic
Arjuna Subject : -
Articles 589 Documents
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Effect of cognitive stimulation therapy in combination with other intervention modalities on cognitive ability in elderly with cognitive impairment: a quasi-experimental study Turana, Yuda; Sani, Tara Puspitarini; Prasetya, Virginia Geraldine Hanny; Suswanti, Ika; Konny, Lisye; Halim, Magdalena Surjaningsih; Handajani, Yvonne Suzy
Universa Medicina Vol. 43 No. 1 (2024)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2024.v43.13-19

Abstract

BackgroundCognitive stimulation therapy (CST) has been proven to be beneficial in improving cognition and quality of life in people with mild cognitive impairment (MCI) and mild dementia (MD). This study investigates the benefit of more frequent exclusively CST intervention compared to less-frequent CST-exercise combination on cognitive ability among elderly people with cognitive impairment. MethodsA quasi-experimental controlled study involving 22 subjects aged = 60 years with cognitive impairment. They were divided into three groups: group A (6 months, weekly CST + exercise sessions, n=13), Group B (3 months, twice-weekly CST-only sessions, n=5), group C (3 months, no intervention, n=4) as control. The Modified Mini Mental State Examination Indonesian Version was used for evaluating the cognitive ability of the elderly subjects. Data were analyzed using one-way Anova and Kruskal-Wallis tests ResultsAll participants completed the study, the majority being female with mean age of 70.43 ± 6.97 years and differences in education level distribution across the three groups. The scores before and after the intervention showed a significant difference in the registration and construction domains (p<0.005). However, there was a greater improvement of the mean difference in cognitive scores in groups A and B compared to the control group, although the difference was not statistically significant (p >0.05). ConclusionA twice-weekly CST-only intervention and a once-a-week CST-exercise combination provide better cognitive improvement than no intervention (control). Therefore, elderly people with cognitive impairment should be encouraged to engage in physical activities, brain training, and group activities for promoting the brain’s ability.
The effect of listening to Holy Quran recitation on stress among healthy adults: a non-blinded randomized controlled trial Hanafi, Muchtar; Rahmatillah, Arif; Wiyono, Nanang; Mirawati , Diah Kurnia
Universa Medicina Vol. 43 No. 1 (2024)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2024.v43.61-68

Abstract

BackgroundStress is the body’s inability to reach a balance between physical or psychological demands and the ability to meet them. Failure to meet these demands has a crucial impact which includes physical, emotional, and behavioral disorders. Recitation of the Quran is believed to cause relaxation by lowering adrenocorticotropic and cortisol hormonal levels. This study aimed to assess the effects of Quran recitation on stress levels using the biofeedback indicators electromyogram, skin conductance, and heart rate among healthy adults. MethodsThis study used a pre- and post-test group design involving 40 males between 19 and 23 years of age, randomized into two groups, i.e. control group (n=20) and Quran recitation listeners (n=20). The subjects were conditioned in a quiet room for 30 minutes before the stress level measurements were taken. The stress level measurements by means of electromyogram, skin conductance, and heart rate were performed with biofeedback before and after giving the stressor tests’ protocol. Statistical analysis using independent t-test was then performed. ResultsThe baseline comparative measurement using biofeedback between control and treatment groups revealed nonsignificant between-group differences in electromyogram, skin conductance, and heart rate (p=0.150; p= 0.389; and p=0.985 respectively). After applying the stress protocol followed by the intervention, the independent t-test revealed significant between-group differences in electromyogram and skin conductance (p= 0.042 and p=0.030), but not in heart rate (p=0.741). ConclusionsOur study demonstrated that Quran recitation has a significant effect in relieving stress levels assessed using biofeedback parameters (electromyogram and skin conductance) among healthy adults.
Correlation of angle kappa with biometry and higher-order aberrations of cataract patients at Prof. Ngoerah Hospital Ophthalmology Clinic Siska, Siska; Suryaningrum, I Gusti Ayu Ratna; Evani, Saphira
Universa Medicina Vol. 42 No. 3 (2023)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2023.v42.314-319

Abstract

Background Advancements in ophthalmic surgery now hinge on intricate interplays among ocular parameters. Angle kappa, measuring deviation between visual and pupillary axes, is crucial, especially in refractive procedures with multifocal intraocular lens implants. The research aimed to correlate angle kappa with biometry and higher-order aberrations (HOA) to enhance surgical outcomes among adult cataract patients at Prof. Ngoerah Hospital Ophthalmology Clinic, Denpasar, Bali. MethodsThis cross-sectional study included 29 male and female cataract patients aged 18-80 years, without prior treatment. All patients had a basic examination that included testing of visual acuity using Snellen chart, autorefractometer, measurement of ocular pressure using non-contact tonometry, and slit-lamp examination for cataract grading. Patients who met the inclusion criteria were then examined for biometry (axial length, spherical equivalent, white-to-white distance, anterior chamber depth) using Nidek AL Scan and for angle kappa and HOA using OPD scan III. ResultsData from 50 eyes of 29 subjects (15 females and 14 males) were analyzed. The mean age of the subjects was 60.6 ± 12.5 years. Age and spherical equivalent had positive correlation with angle kappa (r =0.104, r=0.213), but the correlation was not statistically significant. In this study, interestingly angle kappa was not significantly correlated with HOA, AXL, WTW, and ACD (r = -0.050, r = -0.192, r = -0.104, r = -0.195, p >0.05). ConclusionIn conclusion, angle kappa may increase with age and spherical equivalent. Further study with larger sample size is required.
Assessing patient safety implementation and its associate factors in a pediatric inpatient ward Rukmini, Rukmini; Qomariah, Siti Nur; Savage, Eileen
Universa Medicina Vol. 43 No. 1 (2024)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2024.v43.4-12

Abstract

BackgroundPatient safety is an emerging healthcare discipline with the ultimate goal of reducing errors and harm to patients by implementing quality health services. The provision of patient safety is complex and difficult to achieve. The purpose of this research was to assess patient safety in hospital pediatric inpatient care and factors affecting nurses implementing pediatric patient safety. MethodsThis cross-sectional study involved 80 nurses (male and female) at several private and public hospitals in Surabaya City. The research instruments used were secondary data on patient safety in hospital pediatric inpatient wards, hospital medical records, as well as questionnaires, and observations of the implementation of pediatric patient safety goals. Data were analyzed using multiple logistic regression. ResultsMost participants were female (71.3%), were over 45 years old (18%), and had more than 5 years of work experience in pediatric wards (76%). There were reportedly 145 patient safety incidents, consisting of 46% unexpected events (Kejadian Tidak Diharapkan), 48% nearly injurious events (Kejadian Nyaris Cedera), 6% potential injurious events (Kejadian Potensial Cedera), and 0% sentinel events. Multiple logistic regression analysis showed that nurses who work in less positive working settings are at higher risk of negative implementation of pediatric patient safety than those who work in positive working settings [AOR= 1.85 (95% CI 1.62-4.92)]. ConclusionThis study demonstrated that work setting and frequency of reported events were significantly associated with negative implementation of pediatric patient safety. Therefore, intervention is recommended to minimize unnecessary pediatric patient harm.
Factors that influence refractive errors in premature infants Surasmiati, Ni Made Ayu; Handayani, Ariesanti Tri; Sutyawan, I Wayan Eka
Universa Medicina Vol. 43 No. 1 (2024)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2024.v43.44-50

Abstract

Background The prevalence of refractive errors is reported to be higher in children born preterm. Factors such as gestational age, birth weight, and retinopathy of prematurity status, have a significant impact on the refractive development in preterm infants. Prematurity and low birth weight affect the development of organ systems in infants, including the eyes. In addition to immature retinas, other eye conditions, such as refractive status, are also observed. This study aimed to determine the risk factors of refractive status, specifically refractive errors (spherical equivalent, astigmatism, and anisometropia) in premature infants at a tertiary hospital in Bali. MethodsA cross-sectional study was conducted involving 53 premature infants. This study collected samples from January to August 2023 at the Neonatal Intensive Care Unit of Prof. dr. IGNG Ngoerah General Hospital. Data regarding gender, gestational age, birth weight, retinal condition, spherical equivalent, and refractive disorders were collected. The relationship between risk factors and spherical equivalent, astigmatism, and anisometropia were analyzed using multiple regression analysis with statistical significance set at p<0.05. ResultsHypermetropia is the most common finding in premature infants, followed by myopia and astigmatism. The prevalence of myopia (9.4%) and astigmatism (5.7%) is also more common among newborns of gestational age ≤30 weeks (p=0.024). Chronological age was significantly associated with spherical equivalent (β=0.424; p=0.019). ConclusionIn premature infants, chronological age was the risk factor of spherical equivalent. Other risk factors were not associated with the prevalence of refractive errors among premature infants.
Nicotine reduces cell viability and induces oxidative stress in human gingival fibroblasts Azmi, Sabrina; Hadi, Restu Syamsul; Kusuma, Indra; Suciati, Yulia; Sari, Wening
Universa Medicina Vol. 43 No. 1 (2024)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2024.v43.20-30

Abstract

BackgroundNicotine, as the main component of cigarettes, is known to interfere with the proliferation of human gingival fibroblasts (HGFs) and can trigger oxidative stress. This study aimed to analyze the impact of nicotine on viability, expression of the antioxidant Nrf2, levels of the product of oxidative stress malondialdehyde (MDA), and the migration capacity of HGFs. MethodsAn experimental laboratory study used fibroblasts isolated from healthy human gingiva. The cells were grouped into the non-treatment control group (NTC), the solvent control (SC), and the treatment groups, exposed to nicotine at various concentrations for twenty-four hours. Cell viability was assesed using the cell counting kit-8 (CCK-8), Nrf2 expression was examined using ELISA, MDA level was measured using an MDA kit, and migration capacity was assessed using a scratch assay. Statistical analysis used one-way Anova or Kruskal-Wallis test. A p-value of <0.05 was expressed statistically significant. ResultsThe Cell viability was substantially reduced in the nicotine group compared to the untreated group, accompanied by changes in cell morphology. In contrast, Nrf2 expression increased significantly (p=0.010) in the 5 mM nicotine group compared with the control group. The MDA levels were not significantly distinct across groups (p=0.056). Cell migration was delayed significantly in the 5 mM nicotine group at 72 hours after scratching compared to the control group. ConclusionNicotine decreased HGFs viability and increased Nrf2 expression significantly in a dose-dependent manner. Nicotine at 5 mM concentration did not alter MDA levels but delayed cell migration.
Time to treat the climate and nature crisis as one indivisible global health emergency Abbasi, Kamran; Ali, Parveen; Barbour, Virginia; Benfield, Thomas; Bibbins Domingo, Kirsten; Hancocks, Stephen; Horton, Richard; Laybourn Langton, Laurie; Mash, Robert; Sahni, Peush; Sharief, Wadeia Mohammad; Yonga, Paul; Zielinski, Chris
Universa Medicina Vol. 42 No. 3 (2023)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2023.v42.251-254

Abstract

Evaluation of risk factors of postpartum urinary retention after vaginal delivery Djusad, Suskhan
Universa Medicina Vol. 43 No. 1 (2024)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2024.v43.31-37

Abstract

BackgroundUrinary retention is a condition where a person is unable to urinate even after making sufficient efforts. It can be classified as either acute or chronic, as well as overt or covert. Urinary retention can be caused by various factors such as poor detrusor muscle contraction, a decrease in bladder contractility, anatomical anomalies, impaired neurological coordination while urinating, and disruption of outlet relaxation. The objective of this study was to identify the risk factors of postpartum urinary retention (PPUR) after vaginal delivery. MethodsA cross-sectional study was conducted involving 500 female subjects who were in labor. All data obtained including variables such as age, parity, perineal rupture, episiotomy, history of using assisted vaginal birth during labor, and newborn weight, were compared between female subjects with and without postpartum urinary retention. The data were was analyzed using chi square test and multiple logistic regression analyses as a means to identify risk factors for PPUR. Results Among the 500 patients recruited to our study, 68 (13.6%) had PPUR. Episiotomy and parity were found to be potential risk factors for PPUR (OR=1.84;95% CI = 1.06-3.18 and OR=2.19;95% CI = 1.16-4.12, respectively). Severe perineal rupture was not a risk factor of PPUR (OR= 0.82;95% CI =0.82-5.89). ConclusionThe prevalence of PPUR was quite high. Risk factors identified for PPUR were parity and episiotomy. In clinical practice, healthcare providers should pay more attention to women with these risk factors to prevent PPUR.
Developing a conceptual framework for burnout intervention program in the workplace Sundram, Bala Murali; Kumareswaran, Suriya
Universa Medicina Vol. 43 No. 1 (2024)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2024.v43.88-101

Abstract

This review proposes a comprehensive conceptual framework for developing and implementing burnout intervention programs in the workplace. In recent years, job burnout has become a new and vigorous research hotspot in the field of psychology and human resources management at home and abroad. Job burnout has a serious impact on personal health and performance but also harms the work efficiency, organizational effectiveness, and even social stability of employees. With the escalating concern over employee burnout and its consequent negative impacts on both individual health and organizational productivity, there is a pressing need for effective strategies to mitigate this issue. The framework draws on extensive literature review and theoretical model analysis, integrating key theories such as the Job Strain Model, Effort-Reward Imbalance Model, Conservation of Resources Theory, and the Job Demands-Resources Theory to explore the multifaceted nature of burnout. It identifies critical components of burnout, including symptoms such as emotional exhaustion, depersonalization, and reduced personal accomplishment, and contributing factors such as high job demands, inadequate job resources, and personal traits. Intervention strategies such as exercise have been identified as beneficial in addressing burnout. A systematic review of six studies highlights that aerobic exercise effectively lowers burnout and stress levels among employees. The framework also examines mediating factors such as personality traits and external factors, evaluating outcomes such as improved mental and physical health, enhanced job performance, and better workplace environment. Moreover, this review discusses the sustainability of interventions and emphasizes the importance of tailoring approaches to fit specific organizational contexts. The proposed framework provides a structured approach to understanding and addressing workplace burnout, highlighting the necessity for ongoing research and adaptation of intervention programs to meet evolving workplace dynamics.
Emerging and reemerging human fungal pathogens that affect people with weakened immune systems: a systematic review Genet, Amere; Girma, Abayeneh
Universa Medicina Vol. 43 No. 1 (2024)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2024.v43.102-113

Abstract

BACKGROUNDEmerging and reemerging human fungal pathogens are becoming more closely associated with morbidity and mortality, with 13 million infections and 1.5 million deaths per year. They are most often associated with critically ill and immunosuppressed patients. Therefore, this systematic review focused on emerging and reemerging human fungal pathogens that affect immunosuppressed individuals. METHODS A systematic literature search was performed using PubMed, ScienceDirect, Web of Science, Google Scholar, and other sources (Google engine and manual search using a reference list). The data were extracted in a structured format prepared using Microsoft Excel. RESULTSCryptococcus neoformans, Candida auris, Aspergillus fumigatus, Candida albicans, Nakaseomyces glabrata (Candida glabrata), Histoplasma spp., Mucorales (Rhizopus spp., Mucor spp., Lichtheimia spp., and others), Fusarium spp., Candida tropicalis, Candida parapsilosis, Pichia kudriavzevii (Candida krusei), Talaromyces marneffei and Pneumocystis jirovecii were emerging and reemerging fungal pathogens reported among critically ill and immunocompromised patients including but not limited to HIV patients and patients with infectious diseases such as influenza, COVID-19, and tuberculosis as well as chronic conditions or co-morbidities such as asthma, hepatic cirrhosis, cancer, diabetes, cystic fibrosis (CF), transplant recipients, and chronic obstructive pulmonary disease (COPD). Climate change, agricultural activities, occupational hazards, deforestation, migratory trends of people, soil dispersion, decreased immunity of patients, biofilm development, medication tolerance, and resistance to antifungal therapies are all factors that contribute to the emergence of fungal diseases. CONCLUSIONThis review makes recommendations for policymakers, public health experts, and other stakeholders to improve the response to these fungal infections, including laboratory capacity and surveillance, fostering sustainable research and innovation, implementing public health initiatives, and limiting the development of antifungal drug resistance.

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