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Muhammad Taupik
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Unit Redaksi IJPE, Gedung FOK, Jurusan Farmasi, Fakultas Olahraga dan Kesehatan Universitas Negeri Gorontalo. Jln. Jenderal Sudirman No. 06, Kota Tengah, Kota Gorontalo, 96128, Gorontalo, Indonesia. Surat Elektronik : redaksiijpe@ung.ac.id Telf/Fax : 0435-821698 / 0435-821698 Phone (Whatshaap) : +6281547458537
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INDONESIA
Indonesian Journal of Pharmaceutical Education
Published by Universitas Negeri Gorontalo
ISSN : -     EISSN : 27753670     DOI : https://dx.doi.org/10.37311/ijpe
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Materials Science & Nanotechnology Medicine & Pharmacology
ndonesian Journal of Pharmaceutical Education (IJPE) adalah junal resmi yang diterbitkan oleh Jurusan Farmasi Universitas Negeri Gorontalo yang bekerja sama dengan IAI (Ikatan Apoteker Indonesia) Provinsi Gorontalo. Artikel pada jurnal ini dapat diakses dan unduh secara online oleh publik (open access journal). Jurnal ini adalah jurnal peer-review nasional, yang terbit tiga kali dalam setahun tentang topik-topik keunggulan hasil penelitian di bidang pelayanan dan praktek kefarmasian, pengobatan masyarakat, teknologi kefarmasian serta disiplin ilmu kesehatan yang terkait erat. Jurnal ini menerima naskah berbahasa Indonesia dan Inggris. Berikut merupakan area-area yang difokuskan oleh jurnal ini Farmasi Klinis Farmasi Komunitas Farmasetika Kimia Farmasi Farmakognosi Fitokimia Naskah yang terpilih untuk dipublikasikan di Indonesian Journal of Pharmaceutical Education akan dikirim ke reviewer yang pakar dibidangnya, yang tidak berafiliasi dengan lembaga yang sama dengan penulis dan dipilih berdasarkan pertimbangan tim editor. Naskah yang diterima untuk publikasi adalah salinan yang diedit untuk tata bahasa, tanda baca, gaya cetak, dan format. Seluruh proses pengajuan naskah hingga keputusan akhir untuk penerbitan dilakukan secara online.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 142 Documents
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Analisis Kualitatif Metabolit Sekunder dan Aktivitas Antioksidan Jamur Endofit Cangkang Bulu Babi (Diadema setosum) Widy Susanti Abdulkadir; Mahdalena Sy. Pakaya; Fika Nuzul Ramadhani; Wiwit Zuriyati Uno; Arona Salama
Indonesian Journal of Pharmaceutical Education Vol 3, No 2 (2023): Mei-Agustus 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i2.18019

Abstract

Endophytic fungi are fungi that live in plant tissues for a certain period and can form colonies in the host's tissues without endangering the host itself. In addition to plants, endophytic fungi are also found in marine biota. Endophytic fungi that live in the internal organs or tissues of marine biota, whether in the form of mold or yeast, can transform the nutrients they obtain from their host animals into metabolite compounds which will then be transferred back to the host organs so that they have the same metabolites as their hosts. This study aimed to analyze and test the antioxidant activity of the secondary metabolites of sea urchins in the Tomini Bay area. The method used from the beginning of the research was endophytic microbial fermentation, production of secondary metabolites, and partitioning of endophytic microbial isolates, namely liquid-liquid; the method used to test antioxidant activity was qualitative using TLC plates, DPPH UV-Vis spectrophotometer method, color reagent, and thin layer chromatography. Two isolates of endophytic fungi were obtained, namely (JBB1, JBB2). The isolate that was active as an antioxidant was JBB2 from sea urchins in the Tomini Bay area with an ICso 50-100 ppm, which was in the strong category. Meanwhile, JBB2 isolate was carried out at a wavelength of 517 nm with a value absorbance of 0,707 A. In accordance with the value of the linear equation, it obtained y = 0,092x+36,95 and an R2 value = 0,945 that the ethyl acetate extract in JBB2 had a moderate ICs of 87.43 µg/mL. Meanwhile, the qualitative test of secondary metabolites using thin layer chromatography with n-hexane eluent: ethyl acetate (8:2) ethyl acetate extract contained alkaloid and terpenoid compounds.
Analisis Cemaran Klorin Pada Beras Dengan Metode Volumetri Studi Kasus : Kabupaten Bone Bolango Muhammad Taupik; A. Mu’thi Andy Suryadi; Andi Makkulawu; Jafar La Kilo
Indonesian Journal of Pharmaceutical Education Vol 3, No 2 (2023): Mei-Agustus 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i2.18611

Abstract

Rice is a staple food because it contains protein needed by the body is a source of energy. Rice that is white and shiny sometimes attracts people’s attention. Therefore, to increase buyers’ interest, many sellers add bleaching additives such as chlorine ( a chemical to kill germs) without reckoning the side effects that will be inflicted. This study examines the chlorine content in circulated rice in Bone Bolango Regency. This study used seven rice samples to be analyzed through color and precipitation tests. This research implements a mixed method in the form of qualitative as well as Iodometric and Argentometry titrations for quantitative. The results reveal that in the seven rice samples studied, there was no chlorine content due to the absence of discoloration and precipitate. It is supported by the Iodometric and Argentometric tests which show the results of chlorine levels are at 0%.
Pengaruh Konsentrasi Carbopol 940 Sebagai Gelling Agent Terhadap Stabilitas Fisik Sediaan Gel Lidah Buaya (Aloe Vera) Nur Ain Thomas; Robert Tungadi; Faramita Hiola; Multiani S. Latif
Indonesian Journal of Pharmaceutical Education Vol 3, No 2 (2023): Mei-Agustus 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i2.18050

Abstract

Carbopol 940 is a gelling agent that is very communly used in cosmetic production because of its high compatibility and stability, and it is non-toxic when applied to the skin and it spreads on the skin more easilym gels are semi solid preparations that contain a gel-forming agent which gives stiffiness to collodial solutions or dispersions used for external use on the skin, gel preparations are widely chosen because they are very easy to apply ( easily smeared, absorbed, and cleaned) and more attractive (transparent) compared to the other topical preparations. the purpose of this study was to determine the effect of carbopol concentration 940 as a gelling agent on the physical stability of aloe vera gel preparations. this study began with optimization of the carbopol 940 gel base then the preparation formulation used 50% aloe vera extract, 0,5% carbopol 940 F1, 1 % F2, 2% F3, 10 % propylene glycol, 10% glycerine, 0,1% dm dm hydantoin and sufficient aquadest, afterward the evaluation of the preparation included organoleptic, observations, homogeneity tests, pH tests, spreadability tests, adhesion tests and viscosity tests. carbopol 940 was depeloped using co-free water. gel preparations were 0,5%, 1%, and 2%. the results showed that the thrid formulation (F3) with a concentration of 2% fulfilled the physical evaluation requirements for organoleptic, spreadability, adhesion, viscosity, pH and homogeneity tests.
Narrative Review : Efek Samping Penggunaan Antibiotik Azitromycin Pada Pasien Covid-19 Valentina Dian Suryani; Nera Umilia Purwanti; Nurmainah Nurmainah
Indonesian Journal of Pharmaceutical Education Vol 3, No 2 (2023): Mei-Agustus 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i2.20720

Abstract

Corona virous is the cause of infection with Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). This disease was named by the World Health Organization, namely Coronavirus Disease 2019 or also known as COVID-19. In the management of COVID-19 patients using antibiotic therapy. Azithromycin is a broad-spectrum macrolide antibiotic that is the first line in the treatment of COVID- 19, because azithromycin has anti-inflammatory properties. The purpose of this study was to examine the side effects of using azithromycin as a treatment in COVID-19 patients based on a systematic review of various research articles that have been carried out. The method used is Literature review with SPIDER analysis. The results showed that azithromycin caused side effects in COVID-19 patients in the form of sudden cardiac death by triggering torsade de pointes and other ventricular arrhythmias. The conclusion is that azithromycin has been shown to cause the most side effects in COVID-19 patients.
Evaluasi Penggunaan Antibiotik pada Pasien Pneumonia di Rumah Sakit X Kota Malang Magdalena Tania Tnesi; Agung Permata; Rakhmadani Gadis Aprilianti; Jessica Choirunniswah
Indonesian Journal of Pharmaceutical Education Vol 3, No 3 (2023): September-Desember 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i3.22100

Abstract

Pneumonia is an infection that occurs at the end of the bronchi and alveoli caused by bacteria, fungi, viruses or parasites. This disease is an inflammatory infection that usually consists of a cough and runny nose along with shortness of breath or an increase in the respiratory rate becoming faster. All ages are often affected by this condition, but toddlers are more often affected. One way to treat pneumonia is to use antibiotics, where resistance often occurs if not monitored properly. The aim of this research is to examine the use of the Gyssens technique in accordance with the Republic of Indonesia Minister of Health Regulation No. 8 of 2015 for the use of antibiotics in pneumonia patients at X Hospital, Malang. This type of research is non-experimental qualitative with a descriptive design with a retrospective data collection method. In this research, a purposive sample method was used for the sampling process. The sample used was 80 people. Based on research findings, 95% (76 cases) of antibiotics were given correctly, while only 5% (4 cases) of antibiotics were used incorrectly.
Activity Tests Of Sunscreen Emulgel Preparation of Tamanu Oil (Calophyllum inophyllum L.) Combined With Titanium Dioxide (TiO2) Ni Wayan Devy Indah Lestari; Reslely Harjanti; Dewi Ekowati
Indonesian Journal of Pharmaceutical Education Vol 3, No 2 (2023): Mei-Agustus 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i2.21225

Abstract

Sunlight is the main source of UV rays, exposure to UV rays can have a negative impact on human skin. These negative impacts can be prevented by using sunscreen. The effectiveness of sunscreen can be increased by combining UV filters and natural ingredients. This study aims to determine variations in the concentration of tamanu oil (Calophyllum inophyllum L.) in an emulgel preparation of a combination of tamanu oil and TiO2 which can provide protection as a Sun Protection Factor (SPF) with good physical quality and stability.Tamanu oil is made in 3 concentration variations of 10%; 15%; and 20% and combined with 7% titanium dioxide. Emulgel preparations as a whole were tested for physical quality and stability tests were carried out using the cycling test method. Testing of sunscreen activity in preparations was carried out in vitro using a UV-Vis spectrophotometer at a wavelength of 290-320 nm. The research results were processed statistically.The results of the sunscreen activity test for the emulgel preparation, a combination of tamanu oil and TiO2, showed that all formulas had activity as a sunscreen. The highest SPF value of the emulgel combination of tamanu oil and TiO2 was in formula 6 (20% oil and TiO2) of 9.6 and after the stability test the SPF formula 6 (20% oil and TiO2) was 9.0.
Formulation of Spray Gel Hand Sanitizer from Citronella Oil Using Gelling Agent Carbopol 940 and Humectant Propylene Glycol Nooryza Martihandini; Denada Denada; Shandra Isasi Sutiswa
Indonesian Journal of Pharmaceutical Education Vol 3, No 3 (2023): September-Desember 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i3.22166

Abstract

Citronella (Cymbopogon winterianus) oil contains various phytochemical compounds which have antibacterial activity such as citronellal, citronellol, geraniol, and citral. These compounds can inhibit the growth of Escherichia coli and Staphylococcus aureus, two bacterias  often found on the palm of hands. This study aimed to formulate citronella oil into a spray gel hand sanitizer. It used an experimental laboratory method. Spray gel hand sanitizers were developed from citronella oil using different concentration  of gelling agent Carbopol 940  (0.2%; 0.3%) and humectant propylene glycol (10%; 15%). All formulas were evaluated in term of organoleptic, homogeneity, pH, viscosity, spraying patterns and stickiness. All of the obtained spray gel hand sanitizer presented a white viscous liquid having a distintive odor of citronella. Four formulas  had pH in the range of 6.71 – 6.93 and viscosity in the range of 109.50.8 – 113.50.5 cps. The results showed that formulas 2 and 4 did not meet the requirements for spraying patterns and stickiness because the preparations clumped when sprayed from the spray applicator.  Based on this study, it can be concluded that formula 1 had the best characteristics in term of organoleptic, homogeneity, pH, viscosity, spraying pattern and stickiness. The concentration of carbopol 940 affected the physical properties of spray gel hand sanitizer.
Formulasi dan Evaluasi Mutu Fisik Sediaan Masker Gel Peel-Off Ekstrak Biji Pinang (Areca Catechu L.) Sebagai Antioksidan Asaddah Dwi Mulyani; Mamik Ponco Rahayu; Nur Aini Dewi Purnamasari
Indonesian Journal of Pharmaceutical Education Vol 3, No 3 (2023): September-Desember 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i3.22033

Abstract

Antioxidants are compounds that can reduce free radicals. Antioxidant compounds in the form of synthetic compounds and natural compounds. One of the plants with antioxidant activity is areca nut (Areca catechu L.). Areca seed extract contains secondary metabolites such as flavonoids, triterpenoids, tannins and has potential antioxidant activity. This study aims to determine the differences in PVA base concentration variations on the physical quality and stability tests of peel-off gel mask preparations and the antioxidant activity of piji areca nut (Areca catechu L.) extract.  This study used areca nut powder which was macerated using 96% ethanol. Areca seed extract is made into a formulation for peel-off gel masks using a PVA base with various concentrations of 10%, 12%, and 14%. Testing the physical quality of the gel peel-off mask preparations included organoleptic tests, homogeneity, pH, viscosity, spreadability, adhesion, dry time, and stability tests. Antioxidant testing of mask preparations was carried out using a UV-Vis spectrophotometer at a wavelength of 516 nm. The research results were analyzed using SPSS on the One Way ANOVA method and independent t test. The results showed that areca seed extract can be formulated into a gel peel-off mask preparation with good physical quality. Formula 2 is a gel peel-off mask preparation which has good physical quality. Antioxidant activity in formula 2 has an IC50 value of 71.789 ppm which is a strong antioxidant.
Sintesis Nanopartikel Perak menggunakan Ekstrak Kulit Sirsak sebagai Bioreduktor Riska Yudhistia Asworo; Hanandayu Widwiastuti; Elok Widayanti
Indonesian Journal of Pharmaceutical Education Vol 3, No 3 (2023): September-Desember 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i3.22310

Abstract

Soursop peel can be used as a bioreductor in the green synthesis process of silver nanoparticle formation. This is because the content of secondary metabolite compounds in soursop peel can reduce Ag3+ to Ag0 in nano size. Secondary metabolites in soursop peel are obtained by extraction using a solvent whose polarity value is close to the polarity value of soursop peel secondary metabolites. In this study, ethanol-aquadest and ethanol solvents were used. The extract obtained was then formulated with AgNO3 solution with a concentration variation of 0.5; 1; 1.5 and 2 mM to determine the optimum concentration on the formation of silver nanoparticles. The maximum concentration was obtained at a concentration of 2 mM AgNO3, seen from the highest absorbance obtained at the maximum wavelength observation of 400-450 nm with the concentration of AgNO3 used 2 mM. The silver nanoparticles formed were then analysed using a Particle Size Analyzer (PSA) to determine the size of the nanoparticles formed. Nanoparticles using ethanol-aquadest solvent had a size of 92.83 nm, while those using ethanol solvent had a size of 301.3 nm.
Pengaruh Waktu Ekskresi terhadap Residu Kafein pada Urine Responden Pengkonsumsi Teh Celup Hitam menggunakan Pereaksi Parry Anik Eko Novitasari; Nia Nadia Alfatika
Indonesian Journal of Pharmaceutical Education Vol 2, No 3 (2022): September-Desember 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i3.22162

Abstract

Addictive substance is NAPZA component. Caffeine is one of addictive substance that has psychoactive properties, induce addicted, and as drug for eleminating drowsiness, mood enhancer, performance, and vigilance. This aim study is identification residual of caffeine in urine and urine effect excretion time after consumed a tea to caffeine visible in urine. Black tea is one of caffeine source. Caffeine reabsorbed in tubules kidney and excretion through urine . This study use 10 urine of human as sample examination. Each of them get instruction to consuming of 250 ml tea and record the time after consuming tea till urination. The urine extracted by eter using separating funnel. The urine extract is identified by Parry Reaction in qualitative method. This study has been shown that all of urine sample have contained caffeine residual after consuming tea with green complex colour marked due to Parry Reaction and it visible from 10 minutes until 3 hours after consuming tea. But, this study need some developments about comparing other reaction to identification caffeine in qualitative method, quantitative method to show level of caffeine in and out from body, and special treatment for subjects.

Page 10 of 15 | Total Record : 142

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