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Rahmawati
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INDONESIA
Jurnal Ilmiah Kesehatan (JIKA)
Published by Sarana Ilmu Indonesia
ISSN : 23379847     EISSN : 26862883     DOI : https://doi.org/10.36590/jika
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health
Jurnal Ilmiah Kesehatan (JIKA) aims to provide forum exchanges and interfaces between researchers and related practitioners in the field of health. The journal only accepts articles from original research results (top priorities), case study articles (not priorities), and scientific studies of recent articles (not preferences). JIKA is a scientific journal that contains research papers from the field of health sciences including: Medical and clinical research, food and nutrition research, public health research, obstetrics management research, nursing management research, and pharmacy research.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 268 Documents
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Sorghum Feeding on the Nutritional Status of Body Fat Percentage in Patients with Type 2 Diabetes melitus Zahra, Hanifah Umi; Dwipajati, Dwipajati; Palupi, Fitria Dhenok
Jurnal Ilmiah Kesehatan (JIKA) Vol. 7 No. 2 (2025): Volume 7 Nomor 2 Agustus 2025
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v7i2.1165

Abstract

Dietary management is essential in treating diabetes melitus, with recommendations to limit carbohydrate intake and increase fiber consumption. Modifying both the amount and type of food supports blood glucose control. Sorghum, a local cereal with a low glycemic index of 41 and high fiber content, also contains antidiabetic phenolic compounds, including phenolic acids, flavonoids, and tannins. This study aimed to evaluate the impact of sorghum as an alternative staple food on body mass index (BMI) and body fat percentage in individuals with type 2 diabetes mellitus in Mulyorejo village, Malang City. The study also assessed the relationship between the order of fruit and vegetable consumption, sleep quality, blood glucose, and blood pressure in these patients. An experimental pre-post test control group design was used with 32 subjects. Statistical analysis employed the Wilcoxon difference test at a 95% confidence level (p-value < 0,05). Sorghum intervention significantly reduced BMI (p-value = 0,021 in both groups). For body fat percentage, the p-value was 0,377 in the control group and 0,026 in the treatment group. In summary, incorporating sorghum using the T model plate approach may help reduce BMI and body fat percentage.
Moringa Leaf Extract Cream (Moringa oleifera L.)for Incision Wound Healing in White Rats Dira, Asmarani; Puspitasari, Lia
Jurnal Ilmiah Kesehatan (JIKA) Vol. 7 No. 2 (2025): Volume 7 Nomor 2 Agustus 2025
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v7i2.1267

Abstract

The use of traditional medicinal plants is part of cultural heritage that holds great potential in supporting public health. Moringa leaves are known to accelerate the healing of incision wounds due to their bioactive compounds, including flavonoids, saponins, and terpenoids, which play a role in tissue recovery. This study aimed to evaluate the effectiveness of herbal cream containing Moringa leaf extract at concentrations of 2% w/w and 4% w/w in promoting the healing of incision wounds in white rats, assessed by wound closure length and histopathological examination of inflammatory cells. A true experimental design was applied in this research. The results showed that the Moringa leaf extract cream facilitated wound healing on the dorsal area of white rats within seven days and revealed a significant difference compared to the negative control group. Histopathological analysis demonstrated that treatment with 2% w/w and 4% w/w Moringa extract cream resulted in inflammatory cell counts of fewer than 50. In conclusion, herbal cream formulations containing 2% w/w and 4% w/w Moringa leaf extract are effective in healing incision wounds in white rats.
The Level of Knowledge and Participation of Lestari Waste Bank and Sugema Waste Bank Annashr, Nissa Noor; Muharry, Andy; Yogaswara, Dadan; Rahim, Adzillah Himayati; Ardaya, Putri Maulidiani; Nifiyanti, Useu
Jurnal Ilmiah Kesehatan (JIKA) Vol. 7 No. 2 (2025): Volume 7 Nomor 2 Agustus 2025
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v7i2.1286

Abstract

Lestari Waste Bank was founded in 2022 and started operating in January 2023, located in Tamanjaya Village, Tasikmalaya City and is not yet registered as an active waste bank. One of the waste banks that is active in Tasikmalaya City is the Sugema Waste Bank. The aim of this research was to analyze differences in the level of knowledge and participation among customers of Lestari Waste Bank and Sugema Waste Bank. This research used a cross sectional design. The population was all Lestari Waste Bank customers, totaling 44 people and all customers of Sugema Waste Bank, totaling 110 people. The sampling technique used total sampling for Lestari Waste Bank customers. Meanwhile, simple random sampling was used for Sugema Waste Bank customers, involving 95 people. The independent variable was the type of waste bank. The dependent variables were knowledge and level of customer participation. Data were collected through an interview process with a questionnaire instrument. Data analysis was carried out using univariate and bivariate analysis. Differences in mean of knowledge were analyzed using the Mann-Whitney test. Differences in customer participation levels were analyzed using the chi-square test. The results of the research showed that there was a difference in the mean knowledge of Sugema Waste Bank and Lestari Waste Bank customers (p value <0,05). There was a significant relationship between the type of waste bank and the level of customer participation (p-value <0,05). The conclusion obtained was that the knowledge and level of participation Sugema Waste Bank customers were better than Lestari Waste Bank customers.
Analysis of the Relationship between Nutritional Status and Stress with the Menstrual Cycle in Adolescent Girls Aisyah, Iseu Siti; Neni, Neni; Muharry, Andy
Jurnal Ilmiah Kesehatan (JIKA) Vol. 7 No. 3 (2025): Volume 7 Nomor 3 Desember 2025
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v7i3.1305

Abstract

The causes of menstrual cycle irregularities in adolescents are multifactorial, including nutritional status and stress levels. Irregular menstrual patterns, if left unaddressed, may have long-term implications for reproductive health. This study aimed to analyze the association between nutritional status and stress levels with menstrual cycle patterns in 127 adolescent girls aged 13–15 years from three private junior high schools within the service area of Bantar Community Health Center, Tasikmalaya City. A cross-sectional design was employed. Nutritional status was assessed using anthropometric measurements, stress levels were evaluated through the DASS questionnaire, and data on menstrual cycle regularity and intervals were collected via a structured questionnaire. Chi-square analysis indicated a significant correlation between nutritional status and menstrual cycle patterns (p-value = 0,027), with adolescents experiencing malnutrition showing a higher proportion of menstrual irregularities compared to those with normal nutritional status. Fisher’s exact test also demonstrated a significant association between stress levels and menstrual cycle patterns (p-value = 0,043), with adolescents exhibiting high stress levels having an increased risk of menstrual cycle disturbances. These findings underscore that imbalanced nutritional status and elevated stress levels can disrupt hormonal function and compromise menstrual cycle regularity in adolescent girls. Therefore, monitoring nutritional status and implementing stress management strategies are essential to support regular menstrual cycles and promote reproductive health in this population.
Virgin Coconut Oil and Extra Virgin Olive Oil on Total Cholesterol and Triglyceride Levels in Hyperglycemic Obese White Rats Hakim, Dwi Ashariyanti; Bamahry, Aryanti R.; Namirah, Hanna Aulia; Royani, Ida; Syamsu, Rachmat Faisal
Jurnal Ilmiah Kesehatan (JIKA) Vol. 7 No. 2 (2025): Volume 7 Nomor 2 Agustus 2025
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v7i2.1373

Abstract

The increasing prevalence of obesity and metabolic disorders highlights the need for effective dietary interventions to improve lipid profiles and reduce cardiovascular risk. This study compares the effects of Virgin Coconut Oil (VCO) and Extra Virgin Olive Oil (EVOO) on lipid profiles, specifically total cholesterol and triglyceride levels, in hyperglycemic obese Wistar rats. Obesity and hyperglycemia are major risk factors for cardiovascular diseases and type 2 diabetes. A total of 24 male rats were divided into three groups: a negative control, a VCO group, and an EVOO group. Rats were placed on a high-fat diet for 14 days and administered 2 mL/kg body weight of either VCO or EVOO via oral gavage. Blood samples were collected at baseline, Day 7, and Day 14 for lipid profile analysis. Results revealed that both VCO and EVOO significantly reduced total cholesterol and triglyceride levels compared to the control group. Notably, EVOO resulted in a more substantial reduction in both total cholesterol (to 130,83 ± 24,807 mg/dL) and triglycerides (to 108,17 ± 17,612 mg/dL) by Day 14, surpassing the effects of VCO. These findings suggest that both oils are effective in improving lipid profiles in hyperglycemic obese rats, with EVOO demonstrating superior efficacy. This study provides valuable insights into the potential of VCO and EVOO as dietary interventions for managing obesity-related metabolic disorders, emphasizing EVOO’s greater effectiveness in lipid management.
Ethanol Extract of Bajakah Wood (Spatholobus littoralis Hassk.) on Tyrosinase Concentration and Body Weight in Rats Induced with High-Dose D-galactose Putuh Anisa, Puput; Arika, Luh Ade Lela; Harliansyah, Harliansyah; Sobarna, Nenden Lilis
Jurnal Ilmiah Kesehatan (JIKA) Vol. 7 No. 3 (2025): Volume 7 Nomor 3 Desember 2025
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v7i3.1428

Abstract

The aging process is associated with the accumulation of oxidative stress that damages cellular function. D-galactose is used to induce aging-like conditions in animal models. Bajakah wood extract (Spatholobus littoralis Hassk.), which is traditionally used, is known to contain bioactive compounds with antioxidant activity. This study aimed to elucidate the effects of ethanol extract from Bajakah wood (Spatholobus littoralis Hassk.) on tyrosinase concentration and body weight in rats subjected to high-dose D-galactose induction. This laboratory experimental study used 36 male Sprague Dawley rats induced with D-galactose (500 mg/kgBW). The rats were divided into six groups: normal control, negative control, positive control (vitamin C 50 mg/kgBW), and three treatment groups that received Bajakah ethanol extract at doses of 25, 50, and 100 mg/kgBW. Body weight was monitored weekly for 8 weeks, and tyrosinase levels were analyzed at the end of the study. The negative control group showed fluctuations in body weight and the highest tyrosinase levels. Administration of Bajakah extract, particularly at a dose of 100 mg/kgBW, significantly reduced tyrosinase concentrations (p-value < 0,05) and resulted in a more stable weight gain profile compared to the negative control group. Bajakah wood ethanol extract showed an inhibitory effect on tyrosinase and improved weight stability in the D-galactose-induced rat model. These findings support the potential of this extract as a plant-based therapeutic agent for disorders related to oxidative stress and aging.
Antihyperuricemia of A Combination of Eleutherine bulbosa and Annona muricata Extracts on Reducing Uric Acid Levels in Hyperuricemia Mice Azizah, Sarah; Hujjatusnaini, Noor; Indahsari, Lilin Ika Nur
Jurnal Ilmiah Kesehatan (JIKA) Vol. 7 No. 3 (2025): Volume 7 Nomor 3 Desember 2025
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v7i3.1634

Abstract

Increased uric acid levels in the blood have the potential to cause kidney problems and the formation of urate crystals in soft tissue if not treated properly. Standard treatments involving synthetic drugs, such as allopurinol, often cause side effects, making safer alternatives a necessity. This study aimed to investigate the effect of a combination of Eleutherine bulbosa and Annona muricataextracts on uric acid levels in hyperuricemic mice. This study used a posttest-only control-group design, with 28 male Balb/c mice induced with a high-purine diet, then given single and combination treatments at doses of 100, 200, and 300 mg/kg BW at a ratio of 1:2. Analysis using the Kruskal-Wallis and Mann-Whitney tests showed that the combination dose of 100 mg/kg body weight was most effective in reducing uric acid levels, with an average value of 2,7 mg/dL, while the single extract had no significant effect. At the cellular level, this combination works by inhibiting xantin oksidase (XO) enzyme activity, accelerating uric acid excretion through a diuretic mechanism, and reducing oxidative stress, which in turn helps protect kidney tissue from damage. Therefore, this combination has the potential to be a safe and effective natural antihyperuricemic agent.
Bcr-Abl1 Transcript Variants in Chronic Myeloid Leukemia Patients: Relationship with Routine Hematological Parameters Sela, Grace; Aman, Adi Koesoema; Nasution, Malayana R.
Jurnal Ilmiah Kesehatan (JIKA) Vol. 7 No. 3 (2025): Volume 7 Nomor 3 Desember 2025
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v7i3.1644

Abstract

Chronic myeloid leukemia (CML) was a myeloproliferative neoplasm characterized by the Philadelphia chromosome resulting from the BCR-ABL1 translocation. The most common BCR-ABL1 transcript variants were b2a2 and b3a2, which encoded the p210 protein with increased tyrosine kinase activity. This study was an analytical observational study with a cross-sectional design using retrospective data obtained from medical records. The study analyzed the relationship between BCR-ABL1 transcript variants and routine hematological parameters (hemoglobin, leukocyte count, and platelet count) among CML patients at Adam Malik General Hospital from 2020 to 2024 using a total sampling method. A total of 38 patients met the inclusion criteria, of whom 71,1% had the b3a2 variant and 28,9% had the b2a2 variant. Males predominated (60,5%), with a mean age of 28,37 ± 16,23 years. Leukocyte counts were significantly lower in patients with the b3a2 variant than in those with the b2a2 variant (p = 0,045), whereas hemoglobin and platelet levels showed no significant differences. A statistically significant relationship was found between leukocyte count and BCR-ABL1 transcript variants, while no significant relationship was observed between hemoglobin or platelet levels and transcript variants. The study highlighted the potential association between BCR-ABL1 transcript variants and leukocyte count in CML patients.

Page 27 of 27 | Total Record : 268

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