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LPPM Universitas Sari Mulia Gedung D Lantai 1 JL. Pramuka No. 02 Banjarmasin Kelurahan Pemurus Luar Kecamatan Banjarmasin Timur Kota Banjarmasin Kalimantan Selatan Indonesia
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Journal of Pharmaceutical Care and Sciences
Published by Universitas Sari Mulia
ISSN : -     EISSN : 28284828     DOI : https://doi.org/10.33859/jpcs.
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
Journal of Pharmaceutical Care and Sciences published by the LPPM Sari Mulia UniversityPharmacy department of Sari Mulia University offers a forum for publishing the original research related to pharmaceutical science and clinical research. our focus and scope are Pharmaceutical Technology, Pharmacology & Toxicology, Drug Delivery Development, Pharmacokinetic & Biopharmaceutics, Pharmacoeconomy, Pharmacoepidemiology, Pharmacovigilance, Clinical Pharmacy, Community Pharmacy, Chemical Pharmacy, and Chemical Analysis.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 177 Documents
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A Analisis Kandungan Bahan Kimia Obat Natrium Diklofenak Dalam Jamu Encok Lisaura, Inggrit Windy; Hastika, Febby Yulia; Manurung, Davidson; Mara, Ignatius Ronaldy; Husnati, Lailan; Bariroh, Laili; Rizantha, M. Iqbal
Jurnal Pelayanan Kefarmasian dan Sains Vol 4 No 2 (2024): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v4i2.574

Abstract

Background: Jamu is a traditional herbal medicine made from natural ingredients, inherited as a cultural heritage passed down from generation to generation for health purposes. The increasing use of jamu has led some producers to add pharmaceutical chemicals (BKO) to their products, which can be dangerous and cause side effects for consumers. Purpose: This study aims to analyze the content of sodium diclofenac in jamu used for joint pain relief. Methods: The research methodology includes a qualitative approach using Thin Layer Chromatography (TLC) and a quantitative approach using UV-VIS Spectrophotometry. Results:  The qualitative analysis using TLC on the jamu pegel linu/encok sample tested positive for sodium diclofenac with an Rf value of 0,87. The quantitative test using UV-Vis spectrophotometry yielded an a value of 0,092, a b value of 0,114, and an r value of 0,993. The concentration of sodium diclofenac in the jamu pegel linu sample was found to be 18,90 ppm. Conclusion: The tested jamu sample for joint pain relief contains sodium diclofenac and is not suitable for distribution.  
I Identifikasi Kadar Hidrokunon Pada Krim Pemutih Yang Beredar Di Marketplace Nasiroh, Nasiroh; Rahmadani, Rahmadani; Salwati, Salwati; Alawiyah, Tuti
Jurnal Pelayanan Kefarmasian dan Sains Vol 4 No 2 (2024): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v4i2.596

Abstract

Background: The use of cosmetic products, especially facial whitening creams that contain hydroquinone, can pose a risk to the health of people who use them because they can cause cancer (carcinogenic) and skin disorders such as ochronosis (black skin color). However, in cases in the field, it is often found that hydroquinone content is still present in cosmetic preparations in circulation. Therefore, it is necessary to carry out further research regarding the hydroquinone content in cosmetic preparations. Objective: To determine the content and levels of hydroquinone in samples of whitening cream preparations. Methods: This research uses analytical observational type. Testing was carried out using High Performance Liquid Chromatography (HPLC). Qualitative analysis is carried out by paying attention to retention time, while quantitative analysis is carried out by looking at the area or concentration which is then calculated to obtain hydroquinone levels. Results: The results of research on facial whitening cream circulating in the Shopee, Tokopedia and Bukalapak marketplaces contained hydroquinone in three samples with levels in sample 1 of 0.002204%, sample 4 of 0.03%, and sample 5 of 0.137%.
Studi Farmakognostik Daun Pepaya (Carica papaya L) Asal Banjarmasin Ngongo, Marselina; Hakim, Ali Rakhman; Mustaqimah, Mustaqimah; Darsono, Putri Vidiasari
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 2 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i2.654

Abstract

Latar Belakang: Indonesia memiliki kekayaan alam berupa tanaman yang dapat memberikan manfaat bagi manusia dalam hal pengobatan dan kesehatan, salah satunya adalah daun pepaya. Tanaman ini memiliki banyak manfaat bagi kesehatan, seperti sebagai sumber nutrisi, antioksidan, membantu menjaga kesehatan saluran pencernaan, mengelola diabetes, membantu meredakan peradangan, dan membantu kesehatan kulit. Pada daun pepaya telah diindentifikasi adanya kandungan alkaloid, flavonoid, tanin, saponin dan steroid/triterpenoid. Studi farmakognostik adalah suatu proses sistematis untuk menyelidiki, mempelajari, dan menganalisis suatu topik, masalah, atau fenomena dengan menggunakan metode-metode ilmiah atau pendekatan yang terstruktur.Tujuan: penelitian ini bertujuan untuk memahami sifat-sifat fisik, kimia, dan farmakologis dari simplisia daun pepaya.Metode: jenis penelitian ini adalah penelitian eksperimen, pada pengujian daun pepaya dibuat ekstrak dengan metode maserasi.Hasil: Berdasarkan penelitian hasil analisis menunjukkan bahwa susut pengeringan sampel daun pepaya sebesar -63,04%, sesuai dengan standar farmakope herbal yang mengharuskan susut pengeringan ≤ 10%. Sementara itu, uji kadar ekstrak larut air menghasilkan nilai sebesar 21,976%, sementara uji kadar ekstrak larut etanol menunjukkan nilai sebesar 21,872%. Hasil uji parameter non-spesifik menunjukkan bahwa kadar abu total daun pepaya adalah sebesar 11,025%, sedangkan kadar abu tidak larut asamnya adalah sebesar 0,82%.Simpulan: Metode ekstraksi maserasi dengan pelarut etanol 96% terbukti efektif dalam mengekstraksi senyawa-senyawa tersebut dari daun pepaya
Formulasi Dan Evaluasi Sediaan Fast Disintegratig Tablet Dengan Ekstrak Buah Pare (Momordica charantia L.) Sebagai Anti Diabetes Melitus Gumarus, Ellora Griselda; Budi, Setia; Darsono, Putri Vidiasari; Audina, Mia
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 2 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i2.700

Abstract

Latar Belakang: Diabetes melitus merupakan salah satu penyakit tidak menular yang masuk ke dalam kelompok penyakit metabolik dengan karakteristik atau gejala gula darah yang melebihi nilai normal bisa juga disebut dengan hiperglikemia. Buah pare mengandung senyawa saponin dan senyawa kompleks lainnya yang berperan dalam menurunkan kadar glukosa darah. Explotab diformulasikan dengan ekstrak buah pare menjadi sediaan FDT. Tujuan: Mengetahui efek explotab sebagai penghancur serta perbedaan karakteristik pada sifat fisik tablet yang dihasilkan dalam formulasi fast disintegrating tablet ekstrak buah pare. Metode: Penelitian menggunakan metode quasi experimental dengan rancangan one-group posttest only. Dibuatnya 3 formulasi dengan variasi jumlah explotab berbeda menggunakan metode kempa langsung kemudian dilakukan evaluasi uji waktu alir granul, uji kelembaban granul, uji organoleptis, uji keseragaman bobot, uji kekerasan, uji kerapuhan, uji waktu terdisintegrasi, dan uji waktu hancur. Hasil penelitian dianalisis secara deskriptif dan statistic menggunakan uji perbandingan One Way ANOVA. Hasil: Hasil evaluasi sediaan fast disintegrating tablet ekstrak buah pare dengan variasi explotab memenuhi syarat uji evaluasi sediaan FDT. Simpulan: Dari hasil evaluasi fisikokimia sediaan FDT ekstrak buah pare yang telah dilakukan, semua formulasi memenuhi syarat pengujian FDT
Monitoring Efek Samping Obat Antihipertensi Di Puskesmas Kertak Hanyar Kabupaten Banjar Trisia, Trisia; Kurniawati, Darini; Nastiti, Kunti; Aryzki, Saftia
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 2 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i2.720

Abstract

Latar belakang: Hipertensi adalah suatu keadaan dimana tekanan darah mengalami peningkatan dari keadaan normal atau mencapai 140/90 mmHg. Di Indonesia, prevalensi hipertensi mengalami peningkatan, terutama di Kalimantan Selatan. Penggunaan obat antihipertensi diperlukan untuk mengontrol tekanan darah dan digunakan dalam jangka panjang, namun tidak jarang menimbulkan efek samping yang dapat mempengaruhi kualitas hidup pasien. Maka diperlukan monitoring efek samping obat untuk memantau reaksi tidak diinginkan setelah pemberian obat. Tujuan:  Untuk mengidentifikasi karakteristik pasien yang mengalami efek samping dan mengidentifikasi kejadian efek samping obat antihipertensi. Metode:  Metode yang digunakan pada penelitian ini adalah observasional deskriptif dengan rancangan Cross Sectional dan teknik pengambilan sampel menggunakan teknik pusposive sampling. Instrumen pengambilan data menggunakan lembar observasional berupa kuesioner. Hasil: Berdasarkan hasil penelitian menunjukkan mayoritas responden berusia 56-65 tahun (36,08%), jenis kelamin perempuan (55,70%), pendidikan SD (36,72%) dan bekerja sebagai petani (36,70%). Obat antihipertensi yang paling banyak digunakan adalah Captopril tunggal (44,30%) dan terdapat 110 responden (69,62%) yang mengalami efek samping obat berupa batuk kering (47,27), bengkak (23,63%), pusing (16,36%) dan gatal (12,72%). Simpulan:  Berdasarkan hasil penelitian yang sudah dilakukan dari 158 responden, 110 melaporkan mengalami efek samping obat. Efek samping yang paling umum dilaporkan adalah batuk kering, bengkak, pusing dan gatal.
Evaluasi Penggunaan Antibiotik Pada Pasien Ulkus Diabetikum Rawat Jalan Di RSUD Ulin Banjarmasin Sindi Kornelia; Mukti, Yusuf Anggoro; Aryzki, Saftia; Salwati, Salwati
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 2 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i2.725

Abstract

Latar Belakang: Ulkus diabetikum adalah komplikasi pasien diabetes melitus yang ditandai dengan luka kronis di kaki yang sulit sembuh, akibat kerusakan saraf dan gangguan alir darah. Resistensi antibiotik terjadi akibat penggunaan yang tidak tepat dan meningkatkan resiko amputasi menjadi masalah signifikan pada penanganan ulkus diabetikum. Tujuan: Penelitian ini bertujuan untuk evaluasi penggunaan antibiotik pada pasien ulkus diabetikum rawat jalan di RSUD Ulin Banjarmasin tahun 2023. Metode: Metode penelitian ini obsrvasional deskriftif secara kuantitatif dan kualitatif, diambil secara retrospektif data rekam medis, populasi dan sampel adalah pasien rawat jalan ulkus diabetikum di RSUD Ulin sebanyak 100 sampel. Hasil: Berdasarkan penelitian hasil pada 100 sampel evaluasi metode ATC/DDD dengan total penggunaan antibiotik sebanyak 978,66 DDD/100, antibiotik tertinggi yaitu Cefixim (41,429%) dan antibiotik terendah yaitu Metrodinazole (20,417%). Antibiotik yang termasuk segmen 90% yaitu Cotrimoxazole (36,13%), Cefixim (34,75%), dan Ciprofloxacin (11,18%), sedangkan segmen 10% yaitu Clindamycin (9,54%) dan Metrodinazole (8,41%). Evaluasi metode Gyssens diperoleh kategori 0 sebanyak 40 pasien, kategori I sebanyak 33 pasien, kategori IVA sebanyak 27 pasien. Hasil uji chi square analisis Fisher’s Exact Test kategori Gyssens dengan nilai sig. 0.000<0.05 dan pada penggunaan antibiotik Cefixim, Clindamycin, Ciprofloxacin, Cotrimoxazole, dan Metrodinazole dengan nilai sig. 0.000<0.05. Simpulan: Berdasarkan hasil penelitian penggunaan antibiotik secara kuantitaif dan kualitatif pasien ulkus diabetikum dapat di simpulkan bahwa kuantitas penggunaan antibiotik melebihi standar WHO berpotensi terjadinya resistensi, dan kualitas penggunaan antibiotik pasien ulkus diabetikum rasionalitas dan empiris, dan tidak terdapat hubungan penggunaan antibiotik pada pasien ulkus diabetikum rawat jalan di RSUD Ulin Banjarmasin.
F Faktor Yang Berhubungan Dengan Kejadian Anemia Pada Ibu Hamil Di Wilayah Kerja Puskesmas Cempaka Banjarmasin Rahmina, Anita; Megawati, Megawati; Dewi, Vonny Khresna; Kirana, Rita
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 2 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i2.727

Abstract

Background :  Pregnant women who suffer from anemia can experience negative impacts on themselves and their fetuses, such as fatigue, fetal anemia, low birth weight, premature birth, increased risk of postpartum hemorrhage, intrauterine growth retardation, perinatal death, stillbirth, low tolerance to infection, shortness of breath, and decreased physical and mental performance. Objective : To determine the factors associated with the incidence of anemia in pregnant women in the work area of ​​the Cempaka Banjarmasin Health Center Method : Quantitative non-experimental correlative research design with a cross-sectional approach. The sample in this study was 48 respondents taken using the Accidental sampling technique. The dependent variable is anemia in pregnant women and the independent variables are age, parity and knowledge. The statistical test used chi-square with a confidence level of 95% or (α = 0.05). Results : The results of the study showed that there was a relationship between all variables and anemia in pregnant women. Of all respondents, 10 (20.8%) respondents experienced anemia and 38 (79.2%) respondents did not experience anemia. There is a relationship between age (ρ-value: 0.002), parity (ρ-value: 0.003), and knowledge (ρ-value: 0.009) with the incidence of anemia in pregnant women. Conclusion : The incidence of anemia in pregnant women is influenced by age, parity and knowledge factors in the Cempaka Health Center Work Area.  
P Persepsi Masyarakat Terhadap Pengobatan Menggunakan Tanaman Herbal Di Wilayah Sungai Lulut Banjarmasin Berdasarkan Theory Of Planned Behavior Arga, Ine Andriani
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 2 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i2.730

Abstract

Background: Perceptions regarding medication use vary, including the use of herbal medicines, the experience of information obtained by the community can influence perceptions about treatment, so it is necessary to see how the community perceives it in making treatment decisions. Objective: Knowing the relationship between public perception through the Theory of Planned Behavior approach and treatment behavior using herbal plants. Methods: Analytical observational research with cross sectional. Sampling was carried out using purposive sampling technique. The research sample consisted of 100 respondents. Data was obtained using a questionnaire distributed to the public and analyzed using the Spearman' rho statistical test. Results: The results showed that 91% of respondents had a strong attitude towards carrying out treatment using herbal plants, 87% of respondents had a good attitude towards carrying out treatment using herbal plants, 88% of respondents had a high subjective norm of confidence in carrying out treatment using herbal plants, 83% Respondents have high behavioral control to support or inhibit people's behavior towards treatment using herbal plants. Attitude variables do not have a significant relationship with treatment behavior using herbal plants p value= (0.910), subjective norms have a significant relationship with treatment behavior using herbal plants p value= (0.013) and behavioral control does not have a significant relationship with treatment behavior using herbal plants p value= (0.072). Conclusion: The test results in this study show that there is no relationship between attitudes and behavioral control and people's behavior in carrying out treatment using herbal plants, while subjective norms show that there is a relationship with people's behavior in carrying out treatment using herbal plants using the Theory of Planned Behavior approach 
F Formulasi Sediaan Gel Ekstrak Lidah Buaya (Aloe Barbadensis) Dan Daun Sambung Nyawa (Gynura procumbens) Sebagai Alternatif Penyembuhan Luka Dinofitri, Hanifah; Cathelya, Bunga; Idamanda, Rahma; Putri Aulia, Bilqis; Rizamevia, Fhidila; Maharini, Indri; Sani K, Fathnur
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 2 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i2.732

Abstract

Background: Wound care can involve both chemical and natural substances to accelerate the healing process. Aloe vera is known for its wound-healing properties due to the presence of saponins. Similarly, sambung nyawa leaves aid in wound healing because they contain flavonoids. Combining extracts from aloe vera and sambung nyawa is expected to enhance the healing process. Gel formulations are advantageous as they allow for prolonged drug contact with the wound and protect it from external contamination.Objective: This study aims to evaluate the effect of varying concentrations of Carbopol 940 as a gelling agent on the physical properties and stability of the gel, as well as to assess the effectiveness of the gel in promoting the healing of excision wounds.Methodology: The method used in this study is experimental. The gel formulations consist of four formulas with varying concentrations of sambung nyawa leaf extract and Carbopol. Evaluation of the gel's physical properties includes organoleptic tests, homogeneity, spreadability, adhesiveness, pH, viscosity, and stability tests. The excision wound healing test was conducted on mice using six treatment groups. The observed parameter was the percentage of wound healing. Data analysis was performed descriptively and statistically using One-Way ANOVA.Results: The evaluation results of the formulation showed that the developed formula met the standards for physical properties and stability. The best wound-healing effectiveness was observed in treatment group 4, which contained 4% ethanol extract of aloe vera, 5% sambung nyawa leaves, and 2% Carbopol 940.Conclusion: The variation in Carbopol 940 concentration affects the physical properties and stability of the gel formulation. The effectiveness of excision wound healing indicates that higher concentrations of sambung nyawa leaf extract result in better wound-healing efficacy.  
U Uji Aktivitas Antibakteri Jamur Endofit Batang Bajakah Tampala (Spatholobus Littoralis Hassk) Pada Bakteri Salmonella Typhi Elysa, Elysa; Chandra, M. Andi; Nastiti, Kunti
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 2 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i2.735

Abstract

Bajakah Tampala is often used by the people of Halong District Village for wisa disease or high fever which is believed to be typoid by boiling the bark of Bajakah Tampala (Spatholobus littoralis Hassk) wood. The use of traditional medicine from plants that are abundant in nature. This endophyte is research in the field of biotechnology using small samples from the original plant to obtain the same compounds as the original plant so that biodiversity is maintained. The aim of this research is to determine the type of endophytic fungi produced by Bajakah Tampala stem (Spatholobus Littoralis Hassk) and the greatest antibacterial activity of the endophytic fungi produced by Bajakah Tampala stem (Spatholobus Littoralis Hassk) using the diffusion method and to determine the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) against Salmonella typhi bacteria, the research method stage involves growing endophytic fungi, isolated and separated according to the type of fungus, followed by testing on Salmonella typhi bacteria. The greatest antibacterial activity was then determined by MIC and MBC by making various concentrations, and the positive control was chloramphenicol. The research found three types of endophyte isolates, Bajakah Endophyte Isolate 1 (IEB1), Bajakah Endophyte Isolate 2 (IEB2), Bajakah Endophyte Isolate 3 (IEB3), the results showed the largest potential inhibition zone in the IEB3 isolate was 28.78 mm compared to the antibiotic chloramphenicol with an inhibition zone of 24.42 mm. MIC testing shows the level of turbidity at a concentration of 6.25% and has a MBC that counts the number of colonies at a concentration of 25%. the result of the endophytic fungus Bajakah Tampala stem Spatholobus Littoralis Hassk) which has antibacterial activity and the ability to kill Salmonella typh bacteria

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