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Buletin Kedokteran dan Kesehatan Prima
Published by Universitas Prima Indonesia
ISSN : 28289994     EISSN : 28289994     DOI : https://doi.org/10.34012/bkkp
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health
Media publikasi ilmiah di bidang kedokteran dan kesehatan yang terbit dua kali dalam setahun yaitu pada bulan Maret dan September. Berisi tulisan hasil penelitian lapangan atau laboratorium maupun studi pustaka dari bidang ilmu seperti kedokteran klinis, kedokteran tropis, kedokteran gigi, biomedis, farmasi klinis dan kesehatan masyarakat.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 78 Documents
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Search results for , issue "Vol. 4 No. 1 (2025): March" : 78 Documents clear
The impact of white turmeric rhizome extract on the histopathological characteristics of the pancreas in male wistar rats with diabetes Lubis, Zahra Khairunnisa; Ongko, Nicolas Xavier; Soekardi, Adi; Razoki, Razoki
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6407

Abstract

This study investigates the potential of white turmeric (Curcuma zedoaria Rosc.) rhizome extract as a cost-effective treatment for managing diabetes, focusing on its impact on pancreatic histopathology and blood glucose levels in diabetic Wistar rats. The research employed a randomized pre-test and post-test control group design, with rats induced with alloxan to simulate diabetes. The treatment groups received varying doses of white turmeric extract (250 mg/kg BW, 500 mg/kg BW, and 750 mg/kg BW) for 14 days. Histopathological analysis of the pancreas revealed that the white turmeric extract groups showed no signs of edema, inflammation, or necrosis, indicating a protective effect. Blood glucose level measurements demonstrated that the 500 mg/kg BW dose exhibited the most optimal results in lowering blood glucose levels. Statistical analysis using ANOVA and Kruskal-Wallis tests indicated significant differences between groups. These findings suggest that white turmeric extract, particularly at a dosage of 500 mg/kg BW, holds promise as a complementary treatment for managing diabetes by improving pancreatic health and reducing blood glucose levels. Further research is warranted to explore the underlying mechanisms and optimize its application.
Counseling students to improve fire safety knowledge and preparedness Simanjuntak, Mafe Robbi; Dameria, Dameria; Situngkir, Luwis; Sihombing, Tabita Ronauli; Ginting, Astriani Natalia Br; Sianipar, Milka Rositi
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6530

Abstract

This research investigates the effectiveness of counseling methods, incorporating seminar models and PowerPoint presentations, in enhancing students’ knowledge and preparedness for fire emergency response at Universitas Prima Indonesia. A quantitative approach with a quasi-experimental, one-group pretest-posttest design was employed, involving 78 students from the Public Health Bachelor Program. The intervention comprised four counseling sessions covering basic fire knowledge, preparedness steps, emergency actions, and the use of firefighting equipment. Data was collected through questionnaires administered before and after the intervention, assessing students' knowledge of fire extinguishers, hydrants, fire alarms, assembly points, emergency exits, and emergency stairs. The results indicated a significant positive impact, with post-test scores for both knowledge and preparedness substantially higher than pre-test scores (p < 0.001). Before the intervention, only 25.6% of participants demonstrated good knowledge, while after the intervention, 97.4% achieved this level. Similarly, preparedness levels significantly increased, with 97.4% of participants feeling ready after the intervention compared to only 19.2% before. The study underscores the effectiveness of the implemented counseling methods and supports the recommendation for continuous fire safety education to ensure sustained preparedness.
Clean and healthy living behavior and diarrhea among children: A cross-sectional study in Duria Village, West Nias Sibagariang, Eva Ellya; Simanjuntak, Mafe Robbi; Waruwu, Nestapa Viatni
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6540

Abstract

Diarrheal disease remains a critical public health concern, especially in developing countries like Indonesia, where it significantly contributes to morbidity and mortality among young children. This study aimed to analyze the relationship between Clean and Healthy Living Behaviors (CHLB) and the incidence of diarrhea among children aged 7-10 years in Duria Village, West Nias. A cross-sectional study was conducted from January to February 2024, involving 35 mothers of children aged 7–10 years with diarrhea, selected through purposive sampling. Data were collected using questionnaires to assess handwashing behavior, access to clean water, latrine conditions, and garbage disposal practices. The results indicated that while handwashing habits, latrine conditions, and garbage disposal practices did not show statistically significant associations with diarrhea prevalence, access to clean water had a highly significant association (p < 0.001), albeit counterintuitively suggesting that access to clean water is associated with increased diarrhea. These unexpected findings warrant further investigation to understand potential confounding factors. The study underscores the complex interplay between CHLB and diarrheal disease, highlighting the need for targeted interventions to improve sanitation and hygiene practices in Duria Village.
Squamous cell carcinoma of the kidney: A case report Lina, Juliana; Karo, Reh Malem br; Theresia, Yohani; Fadillah, Qori
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6544

Abstract

Primary renal squamous cell carcinoma (SCC) is a rare neoplasm strongly associated with a history of nephrolithiasis. Renal SCC is reported to have high morbidity and mortality rates, especially in the elderly population. Clinical manifestations of renal SCC are generally characterized by hematuria, flank pain, and a palpable mass in the retroperitoneal area. Histopathological examination reveals the infiltration of squamous cell nests that destroy the stroma. These cells show nuclear pleomorphism, an increased nuclear/cytoplasmic ratio, irregular nuclear membranes, coarse chromatin, prominent and dense basophilic nucleoli, and eosinophilic cytoplasm. These histopathological findings confirm the diagnosis of squamous cell carcinoma. The uniqueness of this case lies in the diagnosis of renal SCC in a relatively young age group, making it a distinct clinical concern. Further immunohistochemical examination, including CK5/6, p63, p40, and CK14 panels, is needed to determine the prognosis and appropriate treatment strategy. This case report emphasizes the importance of understanding kidney stone disease as a preventive measure against the development of renal SCC.
Effectiveness of stretching on reducing muscle and bone pain in worker Siagian, Masryna; Butar-Butar, Emely Thania; Rizki, Kartika Sari; Artiani, Litri; Siregar, Ryskina Fatimah; Putri, Disti Amanda
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6547

Abstract

Musculoskeletal pain is a common work-related ailment in Indonesia. Although not fatal, it can significantly reduce worker productivity. Stretching exercises are often used to alleviate this pain. Pre-work stretching and warm-up exercises may reduce the risk of musculoskeletal pain and fatigue, improve muscle balance and posture, and promote muscle relaxation by lengthening tense muscles, thus increasing comfort during work. This study aimed to determine the effectiveness of stretching in reducing musculoskeletal pain among workers at the Opak Suli Factory in Sukaraya Bakti Village, Pancur Batu District, Deli Serdang Regency. The experimental study employed a pre-test and post-test control group design. All 38 workers at the Opak Suli Factory in Sukaraya Bakti Village, Pancur Batu District, Deli Serdang Regency, were included using total sampling and divided into an intervention group and a control group, each consisting of 19 workers. The intervention group showed a statistically significant reduction in musculoskeletal pain (p < 0.001), indicating that stretching was effective. In contrast, the control group showed no significant change (p = 0.083). In conclusion, stretching is an effective method for reducing musculoskeletal pain among the workers in this study.
Factors contributing to weight gain among students during the COVID-19 pandemic Marpaung, Jelentika; Marlinang, Putri; Siagian, Masryna; Bangun, Andreas Xaverio; Lister, Gilbert; Deseva, Frisca Gemmi; William, Andy
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6582

Abstract

Weight gain among students during the COVID-19 pandemic was largely attributed to lifestyle changes, including diet, sleep patterns, decreased physical activity, and increased gadget use. This study aimed to identify the factors influencing weight gain in students at SMKN 10 Medan. A quantitative methodology was employed, utilizing a cross-sectional approach. The study population consisted of all students at SMKN 10 Medan, totaling 1,108 individuals. A sample of 294 students was selected using a random sampling technique. Data analysis was conducted using the chi-square test and logistic regression. The results indicated that all variables were significantly related to student weight gain during the COVID-19 pandemic, with p-values for physical activity (p=0.036), breakfast habits (p=0.042), snacking habits (p=0.001), sleep patterns (p=0.001), and gadget use (p=0.001). The most influential factors contributing to student weight gain were identified as snacking habits and sleep patterns, which exhibited the lowest significance values. It can be concluded that snacking habits and sleep patterns are the predominant factors associated with weight gain among students at SMKN 10 Medan during the COVID-19 pandemic.
The effect of physical exercise on blood glucose levels in patients with type 2 diabetes mellitus Siregar, Annisa Surto; Ginting, Rapael; Putri, Nadya Nazimuddin; Leslie, William; Hutabarat, Bartimeus Nicomama; Syahputra, Ari Denggan
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6583

Abstract

Diabetes Mellitus (DM) is a chronic metabolic disease characterized by hyperglycemia. This study aimed to analyze the effect of physical exercise on blood glucose levels in patients with Type 2 DM at the Medan Johor Public Health Center. This analytical observational study utilized a case-control design and involved 34 respondents, divided into a case group (with uncontrolled blood glucose levels) and a control group (with controlled blood glucose levels). Data on physical activity, including frequency, duration, and intensity of exercise, were obtained through interviews using the GPAQ questionnaire, while blood glucose level data were sourced from medical records. The results showed a significant relationship between physical activity (p=0.028), frequency of physical exercise (p=0.006), duration of physical exercise (p=0.015), and intensity of physical exercise (p=0.034) with blood glucose levels. Physical exercise performed at least three times a week, for a minimum duration of 30 minutes per session, and at an appropriate intensity proved effective in controlling blood glucose levels in patients with Type 2 DM. This study emphasizes the importance of incorporating physical exercise into the management plan for Type 2 DM.
Risk factors for anemia among pregnant women at Bhayangkara Medan Hospital Putri, Eka Nabila; Asmadinah, Nur; Siagian, Masryna
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6636

Abstract

Anemia is a common complication affecting approximately 30% of pregnant women worldwide. Anemia is defined as a hemoglobin level of less than 11 grams per deciliter (g/dL) in non-pregnant women and less than 10.5 g/dL in pregnant women. This study aimed to determine the prevalence and risk factors of anemia in pregnant women. A cross-sectional study was conducted with 75 samples from 306 pregnant women who underwent ANC at the Bhayangkara Medan Hospital between January and June 2022. The risk factors studied included parity, pregnancy spacing, diet, maternal knowledge, and family support. Data regarding the risk factors were collected using questionnaires and medical records. Frequency distribution calculation and the chi-squared test were used for data analysis. The results showed that 30.7% of pregnant women experienced anemia. Chi-square test results showed that pregnancy spacing (0.001), diet (0.002), maternal knowledge (0.039), and family support were risk factors for anemia in pregnant women. Parity alone was not associated with anemia (0.306). The increased risk of anemia during pregnancy is influenced by short pregnancy spacing, poor diet, lack of maternal knowledge, and lack of family support.
Antimicrobial activity of red dragon fruit peel extract against Staphylococcus aureus for root canal irrigation Daryono, Daryono; Purba, Member Reni; Al-Furqa'an, Muhammad
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6654

Abstract

Staphylococcus aureus is a type of bacteria that can colonise root canals, leading to infection and pain. Root canal irrigants are substances used during root canal treatment, and sodium hypochlorite is the gold standard, despite its toxicity. Red dragon fruit peel has several active compounds with antibacterial properties. This study aimed to determine the effectiveness of red dragon fruit peel extract (Hylocereus polyrhizus) against S. aureus as a root canal irrigant. This was an experimental study with a post-test-only group design. The study population was pure S. aureus. The study consisted of five treatment groups: red dragon fruit peel extract at concentrations of 80%, 40%, and 20%, 0.2% chlorhexidine, and DMSO, with five repetitions. Antibacterial effectiveness was tested using the disc diffusion method. Data were analysed using the Kruskal-Wallis statistical test and Post Hoc LSD. The study results showed average inhibition zone diameters of red dragon fruit peel extract against S. aureus of 12.18±0.228 mm, 11.16±0.305 mm, and 9.54±0.603 mm for concentrations of 80%, 40%, and 20%, respectively. The highest average inhibition zone diameter was found in the positive control (0.2% chlorhexidine), which was 13.20±0.255 mm, while the negative control (DMSO) showed no inhibition against S. aureus. The Kruskal-Wallis test results indicated that there was a significant effect of red dragon fruit peel extract against S. aureus (p=0.0001; p<0.05). The Post Hoc LSD test results showed that there were differences in the effectiveness of red dragon fruit peel extract between the two different groups (p=0.0001; p<0.05). Red dragon fruit peel extract can be used as a root canal irrigant, with a concentration of 80% being the most effective concentration.
Comparison of the effectiveness of robusta coffee bean extract and arabica coffee bean extract on the growth of Candida albicans Adriana, Shirley; Pinem, Pinta Malem; Watri, Desi
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6667

Abstract

Oral thrush, a fungal infection often associated with inadequate oral hygiene, necessitates treatment with antimicrobial agents. Extracts from Coffea canephora (Robusta) and Coffea arabica L. (Arabica) coffee beans contain bioactive compounds that demonstrate inhibitory activity against Candida albicans. This study investigated the comparative inhibitory efficacy of Robusta and Arabica coffee bean extracts on Candida albicans growth. A randomised, post-test only control group design was employed in this experimental laboratory study. Twelve treatment groups were established, and the disc diffusion method was used to assess antibacterial activity. Inhibition diameters were measured using a vernier caliper. Statistical analysis was performed using the Kruskal-Wallis and Mann-Whitney tests. The mean inhibition diameters for Robusta coffee bean extract (Coffea canephora) were as follows: 9.28 ± 2.585 mm at 12.5% concentration, 12.35 ± 0.050 mm at 25%, 14.55 ± 0.050 mm at 50%, 16.50 ± 0.477 mm at 75%, and 18.55 ± 0.477 mm at 100%. For Arabica coffee bean extract (Coffea arabica L.), the mean inhibition diameters against Candida albicans were 8.10 ± 1.117 mm at 25% concentration, 10.91 ± 1.188 mm at 50%, 15.61 ± 2.115 mm at 75%, and 16.71 ± 1.980 mm at 100%. The positive control exhibited a mean inhibition diameter of 15.85 ± 0.180 mm. No inhibition was observed for Arabica coffee bean extract at 12.5% concentration or the negative control. The results indicate that Robusta coffee bean extract demonstrated a significantly greater inhibitory effect on Candida albicans growth compared to Arabica coffee bean extract. Liquid chromatography-mass spectrometry (LC-MS) analysis of both Robusta and Arabica coffee bean extracts revealed the presence of caffeine and chlorogenic acid, which likely contribute to their observed inhibitory activity.

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