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Program Studi Farmasi Fakultas Ilmu Kesehatan, Universitas Muhammadiyah Magelang Jl. Mayjen Bambang Soegeng, Glagak, Sumberrejo, Kec. Mertoyudan, Magelang Jawa Tengah 56172 Telp / Fax : (0293) 326945
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Borobudur Pharmacy Review
Published by Universitas Muhammadiyah Magelang
ISSN : -     EISSN : 27983552     DOI : 10.31603/bphr
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health
BPHR is a peer-reviewed Journal of Pharmacy Studies published by Universitas Muhammadiyah Magelang. This journal published biannually and provides a forum for publishing the original research articles, review articles, and case study on the scope. This journal is issued twice a year and it is a tool for researchers, academics, and practitioners who wished to channel their thoughts and findings in the field of Pharmacy Studies. The scope of this journal include: Pharmaceutical Sciences: Pharmaceutics, Biopharmaceutics, Drug Delivery System, Physical Pharmacy, Pharmaceutical Technology, Pharmaceutical Microbiology and Biotechnology, Pharmaceutical Chemistry, Pharmaceutical Biology. Community and Clinical Pharmacy: Pharmacology and Toxicology, Pharmacokinetics, Pharmaceutical Marketing, Alternative Medicines, Pharmaceutical Management, Pharmacoeconomic, Pharmacoepidemiology, Social Pharmacy, Pharmacy Policies.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 44 Documents
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Formulasi dan evaluasi sediaan masker gel peel-off ekstrak aseton bekatul padi (Oryza sativa) kombinasi dengan minyak atsiri kulit jeruk Bali (Citrus maxima) Hadi, Ismanurrahman; Aulia, Diva; Irawan, Ade
Borobudur Pharmacy Review Vol 3 No 2 (2023): August-Dec
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v3i2.9820

Abstract

Rice bran (Oryza sativa) is a layer of bran that is separated from the rice during removal during milling. In some literature, it is stated that rice bran has ingredients such as B complex vitamins, B15, vitamin E, protein, minerals, fat, fiber, calcium, essential amino acids and phenolic acids. This study aims to determine the formulation for gel peel-off masks with the active ingredient of rice bran acetone extract combined with grapefruit peel essential oil with concentrations of 5, 10, 15% (F1 without extract and F2, F3 and F4, each extract concentrations of 5%, 10%, and 15 %). Physical evaluation of peel-off gel mask preparations was carried out by organoleptic test, pH test, homogeneity test, drying time test, spreadability test, adhesion test; followed by a hedonic (favorite) test. The results of the evaluation of physical properties show that the formulas F1, F2, F3 and F4 have good physical properties and appearance. The hedonic test conducted showed that the panelists liked the peel-off gel mask preparation with the F2 formula the most. Based on this, it can be concluded that, the best formula is F2 ( 5% extract).
Gambaran Penggunaan Obat Analgetik NSAID Di Apotek Hidayah Metro Lampung Periode Januari-Desember 2022 Dahlia, Ajeng; Abdul, Ahwan; Ariastuti, Reni
Borobudur Pharmacy Review Vol 3 No 2 (2023): August-Dec
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v3i2.10354

Abstract

Analgetik NSAID adalah obat yang digunakan untuk mengurangi peradangan, meredakan nyeri, dan menurunkan demam. Penelitian ini bertujuan untuk mengetahui gambaran penggunaan obat analgetik NSAID di Apotek Hidayah Metro Lampung periode Januari – Desember 2023, metode penelitian menggunakan desain deskriptif kualitatif yang diperoleh dari observasi langsung dan pengambilan data secara retrospektif. Sampel penelitian yang digunakan sejumlah 40.056 sediaan. Hasil penelitian didapatkan persentase penggunaan obat NSAID bermerk lebih banyak 31.194 (77,88 %) sediaan dibandingkan analgetik NSAID generik 8.862 (22,12 %) sediaan. Penggunaan analgetik NSAID bermerk lebih banyak secara non resep 31.156 (99,88 %) sediaan, dengan isi zat aktif asam mefenamat 9.149 (29,37 %) sediaan, golongan oksikam 9.430 (30,27 %) sediaan dengan mekanisme kerja nonselektif (COX) 29.306 (94,06 %) sediaan dan berbentuk tablet 29.568 (94,90 %). Penggunaan analgetik NSAID generik lebih banyak secara non resep 8.647 (97,57 %) sediaan, obat yang digunakan piroxicam 3.120 (36,08 %) sediaan, golongan oksikam 3.760 (43,48 %) sediaan dengan mekanisme kerja nonselektif (COX) 7.147 (82,65 %) sediaan, dan berbentuk tablet 29.568 (94,90 %). Kesimpulan: Hasil penelitian ini didapatkan penggunaan analgetik NSAID bermerk lebih banyak, pembelian tanpa resep dokter, obat NSAID dengan isi zat aktif asam mefenamat dan berbentuk tablet yang bekerja secara nonselektif.
Gambaran peresepan obat antiepilepsi pada pasien rawat jalan di Rumah Sakit Jiwa Prof. Dr. Soerojo Magelang periode Januari – Juni 2022 Sari, Dela Puspita; Agusta, Herma Fanani; Yuliastuti, Fitriana
Borobudur Pharmacy Review Vol 4 No 1 (2024): January- June
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v1i1.11058

Abstract

Epilepsy is one of the most important neurological diseases. Epilepsy is often associated with physical injury, mental injury, and severe psychosocial consequences for those affected. The study aims to determine the description of anti-epileptic drug prescribing for outpatients at Prof. Dr. Soerojo Magelang Mental Hospital in January-June 2022. The method used in this research was descriptive, and it took saturated samples in the form of prescriptions from patients who met the inclusion criteria with an age range of 18-40 years. The results of the study showed that the sufferers who received the most antiepileptic drugs were women aged 18-29 years. The average number of drug items per prescription sheet is 1.99 following WHO standards. The most commonly prescribed antiepileptic drug is a single carbamazepine (20.49%), followed by a combination of Carbamazepine with Divalproex Sodium (13.66%) and a combination of Carbamazepine, Clobazam and Divalproex Sodium (12.68%). In contrast, the most common dosage and rules for use of antiepileptic drugs are Clobazam 1mg tablet, dose once a day, 1 tablet (20.78%).
Uji stabilitas fisik formulasi sediaan sirup infusa daun seledri (Apium graveolens L.) dengan larutan pemanis daun stevia (Stevia rebaudiana) Dewi, Indri Kusuma; Alif, Salsa Billa Nur; Ridlo, Achmad
Borobudur Pharmacy Review Vol 4 No 1 (2024): January- June
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v4i1.11565

Abstract

One of the cardiovascular diseases is commonly known as hypertension, which is high blood pressure. It is recognized as a cause of death and is often referred to as the "silent killer." This is because hypertension frequently occurs without symptoms and is only detected after it has caused serious damage to the body. Many hypertension sufferers utilize traditional therapies, one of which is the use of celery plants (Apium graveolens L.). Utilization of celery planted could have been made into a syrup that used natural sweetener content, namely natural sweetener stevia left (Stevia rebaudiana). This research aims to determine the effect of storage time on the results of the stability test of celery leaf syrup preparations with stevia leaf sweetener using the cycled tested method which carried out as many as 6 cycles with temperatures of 4oC and 40oC each for 24 hours by testing parameters included organoleptic, pH, viscosity, clarity and homogeneity. This type of research uses experimental research. The results of the stability of celery leaf infusion syrup preparation (Apium graviolens L.) obtained by the organoleptic test were liquid, had a distinctive celery smell and were yellowish green in color. Celery syrup preparation is homogeneous and cleared during storage, the pH test stability results had an average value of 5.27 and a viscosity of 3.8 cP. The results of the stability tests for organoleptic properties, homogeneity, clarity, pH, and viscosity indicate that no significant differences were found between the cycles, meaning the syrup remains stable during storage
Karakteristik kimia dan sensori pai susu berbahan dasar tepung kedelai (Glycine max L.) dan serbuk daun kelor (Moringa oleifera L.) Devian, Risnanda Vinca; Dewi, Indri Kusuma; Sunarmi, Sunarmi
Borobudur Pharmacy Review Vol 4 No 1 (2024): January- June
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v4i1.11731

Abstract

Along with the development of science and lifestyle, causing people to prioritize processed foods that are not only filling but provide health benefits. Soy flour and moringa leaf powder can be processed because they have content that is used as a food source that is rich in protein, carbohydrates and fat. The purpose of this study was to determine the chemical and sensory characteristics of milk pie preparations made from soy flour and moringa leaf powder. This study used an observational method with a descriptive research design. This study used one formula with the main ingredients of soy flour as much as 100 grams and moringa leaf powder as much as 1,5 grams.. Pie making is done by making skin dough with soy flour as the main ingredient, olive oil as an emulsifier, powdered sugar as a flavor giver and pie filling using moringa leaf powder as a color giver, cornstarch as a thickener, powdered sugar as a flavor giver and low fat milk as a liquid ingredient, then baked at 170 ℃ for 25 minutes. The tests carried out include ash content test, moisture content test, qualitative test of protein content, carbohydrate content and fat content. The results showed that milk pies made from soy flour and moringa leaf powder had an ash content of 3,85 ± 0,42% and a moisture content of 7,17 ± 0,20%. The pies contain protein, carbohydrate and fat. The skin of the pie has a distinctive soybean smell, brownish color, sweet and savory taste and rough texture, while the contents of the pie have a distinctive smell of moringa leaves, green color, sweet taste and soft texture.
Digitalisasi Sebagai Upaya Peningkatan Kepatuhan Penggunaan Obat Pasien Tuberkulosis: Studi Literatur Kartikawati, Nurfina Dian; Febriani, Anisa Putri; Rizki, Rahmania Hafidhotur; Sari, Lutfiana
Borobudur Pharmacy Review Vol 4 No 2 (2024): August-Dec
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v4i2.12745

Abstract

Patient adherence to TB treatment regimen is essential to ensure recovery and prevent drug resistance. The use of drug reminder applications in the management of Tuberculosis (TB) is increasingly growing in the digital era. This literature aims to review the effect of drug reminder applications on TB patient adherence. The method used is a systematic literature review by searching various relevant scientific databases, such as Crossref and Google Scholar, for articles published in the last two years. The keywords in this study are: Tuberculosis; Drug Adherence; Drug Reminder Application. The literature search was conducted by combining Boolean search terms ("AND", "OR"). In 6 articles, the results of the literature showed that the use of drug reminder applications has a positive impact on patient adherence, with several studies showing an increase in adherence of up to 30%. Factors such as ease of use, daily reminder features, and support from health workers determine the success of the application. The main conclusion of this study is that digitalization of drug reminder applications has the potential to be an effective solution in improving TB patient adherence, but further research is needed to evaluate the sustainability of its impact in the long term.
Formulasi sabun padat dengan kandungan minyak atsiri Cymbopogon Nardus L. Agusta, Herma Fanani; Wardani, Arief Kusuma; Hidayatullah, Farizqi Ramadhan
Borobudur Pharmacy Review Vol 5 No 1 (2025): January- June
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v5i1.12831

Abstract

Soap is a self-care product that plays an important role in maintaining body hygiene. The development of the cosmetic industry encourages innovation in soap formulations, one of which uses natural ingredients such as essential oils. Citronella oil is an agribusiness sector commodity with a good market share and high competitiveness. This study aims to develop a solid soap formulation containing Cymbopogon Nardus L. essential oil, which is known to have antimicrobial and antioxidant properties. Soap was made using a mixture of Virgin Coconut Oil and palm oil, NaOH with the addition of Cymbopogon Nardus L. essential oil and distilled water with varying concentrations. The basic physical and chemical properties of soap, such as organoleptic, pH and foam stability were evaluated with good soap parameters based on SNI 3532:1994. Based on the test results on the four formulas with the three parameters carried out, it can be concluded that the addition of citronella essential oil to the tested formulas strengthens the organoleptic characteristics of good solid soap. All formulas have pH values in the range that are slightly less safe for the skin (pH 10-13) as bath soap with SNI criteria (pH 9-11) and foam stability that tends to decrease during the 28 days of testing and outside the range of solid soap foam stability of 60-70% required by SNI 3532: 1994.
Analisis tingkat kepuasan konsumen terhadap pelayanan kefarmasian di apotek pendidikan X Kabupaten Magelang Bunga, Cut Dewi; Rianawati, Luluc; Yulaikah, Ariska; Latifah, Elmiawati; Yuliastuti, Fitriana; Pribadi, Prasojo
Borobudur Pharmacy Review Vol 5 No 1 (2025): January- June
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v5i1.13180

Abstract

The growing recognition of health's significance among the public drives healthcare facilities such as pharmacies, to enhance the quality of their services. Pharmacies are increasingly emphasizing pharmaceutical services that have transitioned from a drug-centric approach to one that prioritizes the patient. This shift aligns with the principle of pharmaceutical care, which focuses on enhancing the quality of life for patients, while also responding to the growing competition in the market and the demands for consumer satisfaction. Educational pharmacies serve a crucial function as a venue for learning and practical experience for future professionals in the pharmaceutical field. This investigation seeks to assess the degree of consumer satisfaction regarding pharmaceutical services at Pharmacy Education X located in Magelang Regency. The study employs a quantitative descriptive methodology utilizing Likert scale measurements. This study employs a cross-sectional design utilizing a questionnaire that encompasses five dimensions: empathy, physical aspects, responsiveness, assurance, and reliability, aimed at assessing consumer satisfaction. The sample included 100 respondents selected through the convenience sampling method. The findings for the empathy dimension were 96.8%, the physical dimension also recorded 96.8%, the responsiveness dimension showed 96.3%, the assurance dimension reached 98.3%, and the reliability dimension was at 97.5%. In summary, there is a high level of satisfaction among consumers regarding the pharmaceutical services provided at Educational Pharmacy X in Magelang Regency, reflected in an impressive average consumer satisfaction percentage of 97.14%.
Uji kandungan fenolik total dan aktivitas antioksidan ekstrak etanol biji kelor (Moringa Oleifera L.) dan daun sirih cina (Peperomia Pellucida L.) Hafidz, Rosyadah; Abdul, Ahwan; Ariastuti, Reni Ariastuti
Borobudur Pharmacy Review Vol 5 No 1 (2025): January- June
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v5i1.13260

Abstract

Moringa seed (Moringa oleifera L.) and Chinese betel leaf (Peperomia pellucida L.) extracts obtained using ethanol contain phenolic compounds that function as natural antioxidant compounds. research aimed to quantify the overall phenolic content and assess the antioxidant activity of both extracts using Folin-Ciocalteu and DPPH techniques. The extraction process was performed using the maceration technique with 96% ethanol as the solvent, after which analysis It was performed to determine the overall concentration of phenolic compounds and IC50 a measurement that served as an index of antioxidant power. The findings showed that the extract from Chinese betel leaves had a higher a total phenolic content of 91.02 mg gallic acid equivalents (GAE) was recorded. compared to Moringa seeds which had 54.90 mg GAE/g±0.47. Antioxidant activity testing revealed that the IC50 value of Chinese betel leaf extract reached 3,349 ppm, while moringa seed extract showed an IC50 value of 4,701 ppm. For comparison, vitamin C had a lower IC50 of 1,988 ppm. With IC50 values below 50 ppm, both extracts are categorized as very strong antioxidants.
Kualitas mikrobiologi basis pelembab dari lemak daging Sapi metode low temperature dan bouble boiling berdasarkan angka lempeng total (ALT) Kurniawati, Triani; Luviriani, Eva; Rahasasti, Indri Dwi; Calyptranti, Rosellynia; Shafly, Alman
Borobudur Pharmacy Review Vol 5 No 1 (2025): January- June
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v5i1.13560

Abstract

Dry skin is a problem that bothers many people. One of the causes of dry skin is skin dehydration, which can be overcome by using moisturizing cosmetics. Vaseline is a moisturizer commonly used by the public because it does not cause allergies and has good moisturizing capabilities. However, it is derived from non-renewable petroleum, necessitating alternatives. Animal fats can be used as cosmetic moisturizers and are considered safer than chemical substances like zinc oxide. According to BPOM, cosmetic products must pass safety tests such as microbial contamination, heavy metal contamination, and chemical contamination tests. Beef fat contains water and fatty acids that can create a suitable medium for microbial growth. However, temperature and water content affect microbial growth, necessitating further research on the microbiological quality of beef fat using low temperature and double boiling methods. This study aims to determine the microbiological quality of beef fat moisturizer bases using low temperature and double boiling methods through Total Plate Count (TPC) testing. This research is a pre-experimental study with a one-shot case study design. The results show that the TPC values of beef fat using low temperature and double boiling methods are each 1 x 10^4 CFU/g. This indicates that the TPC values of beef fat using low temperature and double boiling methods do not meet BPOM criteria, which is < 500 CFU/g. Keywords: Moisturizer; Beef Tallow; Low Temperature; Double Boiling; Total Plate Count.

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