cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Salman
Contact Email
salman.kimia@gmail.com
Phone
+6285277011177
Journal Mail Official
admin@journal-jps.com
Editorial Address
Fakultas Farmasi Universitas Tjut Nyak Dhien Jl. Gatot Subroto Gg. Rasmi No. 28, Sei Sikambing C. II, Medan Helvetia, Kota Medan, Sumatera Utara 20123
Location
Kota medan,
Sumatera utara
INDONESIA
Journal of Pharmaceutical and Sciences.
Published by Universitas Tjut Nyak Dhien
ISSN : -     EISSN : 26563088     DOI : https://doi.org/10.36490/journal-jps.com
Core Subject : Health, Science, Agriculture, Engineering,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health
Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, Medicinal Chemistry, Molecular Pharmacology, Novel drug delivery system, Nanotechnology, Analytical Chemistry, Organic Chemistry, Natural Chemistry, Polymer Sciences, Clinical Pharmacy, pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, government policies related to pharmacy, pharmaceutical care, Medical Biotechnology, Biochemistry, food chemistry, health and applied sciences relevant to the field of pharmacy. Journal of Pharmaceutical and Sciences (JPS) accepts manuscripts in Indonesian Language (Bahasa Indonesia) with titles and abstracts in bilingual, both Indonesian and English. We accept article manuscripts in the form of original research, literature reviews, and systematic reviews. We do not accept articles in the form of case reports
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 654 Documents
 44   45   46   47   48 
Pengaruh Metode Ekstraksi Daun Jarak Cina (Jatropha multifida L.) Secara Maserasi dan Microwave-Assisted Extraction (MAE) Terhadap Aktivitas Antijamur Pada Candida albicans Aryunda, Divia; Nasution, Muhammad Amin; Nasution, Haris Munandar; Pulungan , Ainil Fithri
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.868

Abstract

Introduction: Indonesia possesses high biodiversity, including the Jatropha multifida L. plant, which contains secondary metabolites with potential antimicrobial properties. Traditionally, the leaves of Jatropha multifida have been used as herbal medicine, particularly for inhibiting the growth of microorganisms. Objective: This study aims to determine the total flavonoid content in the ethanol extract of Jatropha multifida leaves and to compare the effectiveness of two extraction methods, maceration and Microwave-Assisted Extraction (MAE), in inhibiting the growth of Candida albicans. Methods: The research stages included the characterization of the powdered simplicia, extraction of Jatropha multifida leaves using 96% ethanol by maceration and MAE methods, and phytochemical screening. The total flavonoid content was determined using UV-Vis spectrophotometry at a wavelength of 431 nm. Antifungal activity against Candida albicans was tested for each extract at specific concentrations. Results: The ethanol extract obtained through maceration showed a total flavonoid content of 34.7089 ± 0.1206 mg QE/g, while the MAE method yielded 32.1923 ± 0.1113 mg QE/g. The highest antifungal activity was observed in the MAE extract at a 75% concentration, producing an inhibition zone of 24.7 mm. The maceration extract at the same concentration produced an inhibition zone of 23.7 mm. As a positive control, 2% ketoconazole resulted in an inhibition zone of 31.4 mm. Conclusion: Although the maceration method produced a higher total flavonoid content, the extract obtained through the MAE method demonstrated more potent antifungal activity against Candida albicans at the same concentration.
Peran Kurma dalam Meningkatkan Kadar Hemoglobin pada Perempuan: Scoping Review Kalsum, Umi; Putri, Ayu Syah; Ali, Sarina
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.869

Abstract

Iron deficiency anemia (IDA) is a major global health issue that predominantly affects adolescent girls and pregnant women, particularly in developing countries. Dates (Phoenix dactylifera), a natural iron-rich food with essential nutrients, have been proposed as a potential intervention to increase hemoglobin levels. This scoping review aims to explore and evaluate current scientific evidence on the effect of various date varieties in improving hemoglobin levels in women with iron deficiency anemia. Using the Joanna Briggs Institute guidelines, a comprehensive literature search was conducted across ten databases, covering studies from January 2014 to October 2024. Twelve studies meeting the inclusion criteria were analyzed descriptively. The majority reported a significant increase in hemoglobin levels among participants consuming dates, with improvements ranging from 1.18 to 1.67 g/dL. Varieties such as Ajwa, Sukari, and black dates showed notable effectiveness. Some studies also recorded increases in ferritin levels, indicating an improvement in iron reserves. The findings support the use of dates as a beneficial dietary supplement for improving hemoglobin and iron status in women, especially adolescent girls and pregnant women. Further research is necessary to determine optimal dosage and compare the efficacy across different date varieties.
Karakterisasi, Skrining dan Uji Aktivitas Antibakteri Ekstrak Etanol Bunga Kecombrang (Etlingera elatior (Jack) R.M.Sm) terhadap Staphylococcus aureus Khairunnisa , Ardina; Yuniarti, Rafita; Dalimunthe, Gabena Indrayani; Rani, Zulmai
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.870

Abstract

Background: Torch ginger (Etlingera elatior (Jack) R.M.Sm) is a traditional medicinal plant with potential antibacterial properties due to its secondary metabolites, such as flavonoids, tannins, and terpenoids. Staphylococcus aureus is a pathogenic bacterium causing various infections, and increasing antibiotic resistance necessitates alternative treatments. This study aims to explore the antibacterial potential of torch ginger flower ethanol extract against S. aureus. Objective: This research aimed to characterize the phytochemical content of torch ginger flowers, screen for bioactive compounds, and evaluate their antibacterial activity against S. aureus. Methods: The study employed an experimental design, including phytochemical screening, ethanol extraction (maceration), and antibacterial testing using the disk diffusion method at concentrations of 10%, 30%, 50%, 70%, and 90%. Data were analyzed using one-way ANOVA. Results: Phytochemical screening revealed the presence of alkaloids, flavonoids, tannins, saponins, steroids/triterpenoids, and glycosides. The ethanol extract exhibited antibacterial activity against S. aureus, with inhibition zones of 11.9 mm (weak) at 10%, 16.1 mm (moderate) at 30%, and 21.3–22.5 mm (strong) at 50–90%. Statistical analysis confirmed significant differences (p < 0.05) between concentrations. Conclusion: Ethanol extract of torch ginger flowers demonstrated dose-dependent antibacterial activity against S. aureus, supporting its potential as a natural antibacterial agent.
Pemetaan Saintifik terhadap Potensi Tanaman Brassicaceae sebagai Anti-inflamasi: Analisis Bibliometrik Periode Tahun 2003−2024 Tivanie, Riza Ayu; Murti, Yosi Bayu; Illian, Didi Nurhadi; Nugroho, Agung Endro
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.871

Abstract

The Brassicaceae family is recognized for its antioxidant and anti-inflammatory properties. Due to its widespread distribution, it serves as a prominent source of bioactive phytochemicals, attracting considerable research interest. Brassicaceae plants contain several secondary metabolites, including glucosinolates, which are precursors to bioactive compounds like isothiocyanates (e.g., sulforaphane) that have demonstrated anti-inflammatory effects. This study aims to investigate keywords, countries, number of publications, institutions, authors, and journals related to Brassicaceae plants as anti-inflammatory agents during the period 2003–2024 using a comprehensive bibliometric analysis method. Information was collected using the Scopus database, followed by data analysis using the Biblioshiny R Package and VOSviewer. A total of 760 articles meeting the inclusion criteria were analyzed. The results indicate that 2023 saw the largest increase in research publications, with China emerging as the leading contributor, while the USA had the highest citation count. The International Journal of Molecular Sciences was identified as the most popular publishing journal. Kyung Hee University was designated as the most productive institution, with Li Y as the author with the highest contribution. Bibliometric data also highlighted several therapeutic target molecules, including cytokines, nitric oxide, cyclooxygenase-2, and Nrf2, which play crucial roles in the action mechanisms of signature metabolites from Brassicaceae plants, including sulforaphane, isothiocyanates, glucosinolates, and flavonoids, for therapeutic purposes as anti-inflammatory, antioxidant, antimicrobial, and chemopreventive agents. These findings highlight the significant potential of Brassicaceae medicinal plants for various therapeutic mechanisms and provide recommendations for future research in the pharmacy field.
Formulasi dan Uji Aktivitas Antibakteri Sediaan Sabun Cair Ekstrak Etanol Daun Kopi Arabika (Coffea arabica L.) Terhadap Bakteri Staphylococcus aureus Amaliana, Amaliana; Nasution, Haris Munandar; Lubis, Minda Sari; Rahayu, Yayuk Putri
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.872

Abstract

Coffee leaves (Coffea arabica L.) are a part of the coffee plant that is not widely used. Coffee leaves contain flavonoids, alkaloids, saponins, caffeine and polyphenols. Coffee leaves are a natural ingredient that has antibacterial and antioxidant activity, so they need to be used. develop it into pharmaceutical preparations to increase ease of use, one of which is liquid soap preparations The aim of this research was to determine the secondary metabolite content of simplicia powder and ethanol extract of coffee leaves, formulate ethanol extract of coffee leaves into liquid soap, determine the physical quality of the preparation and test the activity against Staphylococcus aureus bacteria. The method used in this research is to make a liquid soap formulation from Arabica coffee leaves and test its effectiveness as an antibacterial against Staphylococcus aureus bacteria. This research was carried out experimentally with the independent variable being the concentration of Arabica coffee leaf ethanol extract: F1 contains 2.5 grams of active substance, F2 contains 5.0 grams of active substance, F3 contains 7.5 grams of active substance, dependent variable: leaf simplicia phytochemical screening test Arabica coffee, antibacterial activity test against Staphylococcus aureus bacteria. Quality of liquid soap preparations from ethanol extract of Arabica coffee leaves using stability tests (pH of the preparation, homogeneity, viscosity and height of foam) and antibacterial tests using the agar diffusion method (well method). The research results show that simplicia powder and ethanol extract of coffee leaves contain alkaloid, flavonoid, tannin and saponin chemical compounds. The organoleptic test results of liquid soap have a distinctive smell, a combination of coffee and rose leaves, are blackish brown in color, and are in the form of a thick liquid. The stability test results of all formulas are stable. The pH test ranges from 9.05 to 9.43. Test foam height 35- 40 mm. The viscosity test results ranged from 735.0-894.8 cpoise, antibacterial activity had an k- (Blanko) concentration inhibition zone of  13,6 mm FI concentration liquid soap obtained a result of 15.7 mm, FII concentration liquid soap obtained a result of 18.4 mm, FIII concentration liquid soap obtained a result of 18.75 mm compared to the control positive obtained a result of 18.8 mm.
Konsentrasi Hambat Minimum dan Konsentrasi Bunuh Minimum Ekstrak dan Nanopartikel Ekstrak Etanol Daun Kubis (Brassica oleracea L.) Terhadap Malassezia furfur Rafika, Intan Maya; Rahayu , Yayuk Putri; Nasution , Haris Munandar; Miswanda, Dikki
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.874

Abstract

Background: Dandruff is a condition characterized by excessive shedding of dead skin cells on the scalp, often accompanied by itching and inflammation. The causes of dandruff can be related to excessive secretion of sweat glands or the presence of microorganisms on the scalp that produce specific metabolites that trigger dandruff formation. The organism believed to be the leading cause of dandruff is Malassezia furfur. Treatment for dandruff can be done through various methods, one of which is using natural extracts, such as ethanol cabbage extract, known for its antifungal properties. In this study, the ethanol cabbage extract will be synthesized into nanoparticle form to enhance its effectiveness. Objective: The objective of this study is to create nanoparticles from ethanol cabbage extract and to compare the antifungal activity of the cabbage extract and the nanoparticle extract of cabbage against Malassezia furfur, focusing on the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC). Method: This study was conducted experimentally, and two variables were tested. The independent variables included the concentration of cabbage extract (6.25%, 12.5%, 25%, and 50%) and nanoparticle cabbage extract (0.625%, 1.25%, 2.5%, and 5%). The dependent variables were the antifungal activity measured by MIC and MFC tests against Malassezia furfur. Nanoparticles were synthesized using the top-down method with high-speed homogenization (HSH) technique. The particle size characterization was performed using a Particle Size Analyzer (PSA). Results: Particle size characterization showed that the particle size of cabbage extract was 2203.45 nm, while the nanoparticle size after synthesis was 408.33 nm. Based on the MIC and MFC tests, it was found that the nanoparticle ethanol cabbage extract at a concentration of 1.25% was more effective than the ethanol cabbage extract at 12.5%. Additionally, the MFC value of the nanoparticle ethanol cabbage extract at a concentration of 5% was more effective than that of the ethanol cabbage extract at 50%. Both preparations demonstrated good sensitivity against Malassezia furfur. Conclusion: Nanoparticle ethanol cabbage extract showed better antifungal activity than the ethanol cabbage extract at higher concentrations. These results indicate that using nanoparticles can reduce the required dosage to achieve optimal effectiveness, thus improving the efficiency of the drug in dandruff treatment.
Hubungan Status Ekonomi dan Pengetahuan Ibu Dengan Sikap Ibu Dalam Melakukan Baby SPA Pada Bayi Usia 3-12 Bulan di Klinik Siti Hajar Pasaribu, Renti Magdalena Br; Sasmartih, Rati; Sitinjak , Regina; Hia, Regina Midar Hati; Siregar, Debi Novita
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.875

Abstract

Background: Baby Spa or Solus Per Aqua refers to water-based therapy aimed at relaxing the body through scrubbing, massage, and infant exercises. Many mothers who have babies are not familiar with the term baby spa and do not know the techniques of doing baby spa, especially in the middle to lower class areas. Objective: This study aims to determine the relationship between economic status and maternal knowledge with the mother’s attitude in doing baby spa for babies aged 3-12 months at the Siti Hajar Clinic. Methods: This method uses quantitative research with a correlation study research design. In this study, the population in this study are all mothers who have babies aged 3-12 months at the Siti Hajar Clinic, totaling 30 people. The sample amounted to 30 respondents. The technique used for sampling is total sampling. Data collection using questionnaires. Data analysis used is univariate and bivariate analysis with Chi-Square test. Results: Based on the results of the chi-square test regarding the relationship between economic status and maternal knowledge with the mother’s attitude in doing baby spa for infants aged 3-12 months, the p-value is 0.001 (p < 0.005). Conclusion: So it will be concluded that ????0 is not accepted ????1 is accepted which means that there is a relationship between economic status and maternal knowledge with the attitude of mothers in doing baby spa for babies aged 3-12 moths at the Siti Hajar Clinic.
Hubungan Riwayat Kunjungan ANC, Paritas Dan Pendidikan Dengan Kejadian BBLR Di Klinik Pratama Mariana Purba , Firda Rebiani Br.; Hanum, Parida; Sinaga , Junita Maria Medelina; Rafianef, Ghina Zahwa; Sianturi, Firnawi
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.877

Abstract

Background: Low Birth Weight (LBW) infants are those born with a weight of less than 2,500 grams. The incidence of LBW can be influenced by several risk factors, including antenatal care (ANC) visit history, parity, maternal education level, and employment. Objective: This study aimed to examine the relationship between ANC visit history, parity, and education level with the incidence of LBW at Klinik Pratama Mariana in 2024. Methods: This was a quantitative study with a retrospective design. Data were collected using total sampling through observation sheets and questionnaires completed by respondents. The study population consisted of 55 mothers who gave birth at Klinik Pratama Mariana Tanjung Gusta, with the sample including those who delivered LBW infants. Data were analyzed using univariate and bivariate analyses with the chi-square statistical test. Results: The results showed a significant relationship between irregular ANC visits and the incidence of LBW (p-value = 0.000). High parity (≥3) also showed a significant association with LBW incidence, observed in 92% of respondents (p-value = 0.000). Furthermore, low educational level (<senior high school) was significantly associated with LBW, found in 85% of respondents (p-value = 0.000). Conclusion: There is a significant relationship between ANC visit history, parity, and maternal education level with the incidence of LBW. Health workers are expected to enhance monitoring and provide counseling for pregnant women with risk factors to help prevent LBW.
Hubungan Karakteristik dan Perilaku Ibu dalam Pemberian MP-ASI dengan Kejadian Gerakan Tutup Mulut (GTM) serta Status Gizi Bayi Usia 12-24 Bulan Hafiza , Haura; Wani , Afivah Putri; Fitri , Aida; Sihombing , Esmina; Hutajulu , Dwi Elalia Br; Nababan, Tiarnida
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.878

Abstract

According to WHO 2022 data, approximately 45 million toddlers worldwide experience wasting, with malnutrition being a major contributor to child mortality. One contributing factor is suboptimal complementary feeding practices. Food Refusal Behavior (FRB), characterized by a child's mouth-closing and eating refusal, is a common phenomenon during complementary feeding that may affect nutritional status. This quantitative cross-sectional study was conducted at Hj Hanum Clinic with 43 respondents selected through total sampling to analyze the relationship between maternal characteristics/behaviors and the incidence of FRB and nutritional status in infants aged 12-24 months. Data were collected through questionnaires and observations, then analyzed using chi-square tests. Results revealed significant associations between FRB incidence and parity (p<0.001), maternal behavior (p<0.001), and maternal occupation (p=0.002). Similarly, child nutritional status showed significant relationships with these three factors. However, maternal education demonstrated no significant association with either FRB incidence (p=0.539) or child nutritional status (p=0.149). These findings underscore the importance of considering parity and maternal behavior in FRB prevention and nutritional status improvement, while formal maternal education appears non-determinative in this context.
Hubungan Pemberian MPASI Pada Bayi Usia 3-5 Bulan Dengan Kejadian Obesitas di Wilayah Desa Tanjung Gusta Gultom, Mona Vebiyanti; Simatupang, Helmalia Alnesa; Nurlita, Ira; Gea, Jernihati; Siregar, Debi Novita
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.879

Abstract

Background: Obesity is a medical condition characterized by excessive fat accumulation that exceeds standard weight-for-height thresholds. One of the factors causing obesity is diet and nutritional intake, so obesity greatly affects children's growth and development. Globally, around 42 million children under five suffer from obesity, representing a major public health concern. One of the factors causing obesity in babies is early provision of MPASI. Objective: To find out whether MPASI at the age of 3-5 months is related to the incidence of obesity in the Tanjung Gusta Village Area. Method: This research uses a quantitative type of research with a cross sectional research design. This research uses data collection methods for measuring body weight (BB) and height (TB), as well as questionnaires which are filled out by respondents according to the instructions given. The type of data collected in this research is primary data obtained directly from respondents through a questionnaire which includes questions related to dependent and independent variables, as well as secondary data obtained by researchers indirectly through midwives in the Tanjung Gusta Village Area. Where researchers want to know the relationship between giving MP-ASI to babies 3-5 with the incidence of obesity in the Tanjung Gusta Village area. Results: It can be seen from the results of the chi-square correlation test of the relationship between giving MP-ASI to babies aged 3-5 months and the incidence of obesity in the Tanjung Gusta Village area. The test was carried out using the chi-square correlation test and obtained an Asymp Sig of 0.002 < 0 .05 means there is a relationship between giving MP-ASI to babies aged 3-5 months and the incidence of obesity in the Tanjung Gusta Village area.

Page 46 of 66 | Total Record : 654

 44   45   46   47   48 

Filter by Year

2018 2026


Reset
Filter By Issues
All Issue JPS Volume 9 Nomor 1 (2026) JPS Volume 8 Nomor 4 (2025) JPS Volume 8 Nomor 3 (2025) JPS Volume 8 Nomor 2 (2025) JPS Volume 8 Nomor 1 (2025) JPS Volume 7 Nomor 4 (2024) JPS Volume 7 Nomor 3 (2024) JPS Volume 7 Nomor 2 (2024) JPS Volume 7 Nomor 1 (2024) JPS Volume 6 Nomor 4 (2023) JPS Volume 6 Nomor 3 (2023) JPS Volume 6 Nomor 2 (2023) JPS Volume 6 Nomor 1 (2023) Suppl. 1, No. 1 (2023) JPS Volume 1 Nomor 1 (2018) More Issue