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Lembaga Penelitian dan Pengabdian Masyarakat (LPPM) Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Jl.Pajajaran No 1. Kelurahan Pamulang Barat, Kecamatan Pamulang, Kota Tangerang Selatan, Banten, 15417 No. Telp : (021) 7471628
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Pharmaceutical Science Journal
Published by Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang
ISSN : 28078535     EISSN : 29861993     DOI : 10.52031/Phrase
Core Subject : Health,
Medicine & Pharmacology
Pharmaceutical Science Journal is a periodical scientific journal published by Pharmacy Major in STIKes Widya Dharma Husada. Pharmaceutical Science Journal accepts scientific papers in the form of research reports (original article research papers), systematic review, and meta analysis with focus and scope: Pharmaceutical Technology Pharmacology and Toxicology Pharmaceutical Chemistry Pharmaceutical Biology Clinical and Community of Pharmacy Management of Pharmacy Biopharmaceutics Pharmaceutical Microbiology and Biotechnology Pharmacocinetics Alternative Medicines Cosmetic Technology
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 90 Documents
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EVALUASI FISIK FORMULASI SEDIAAN OBAT KUMUR YANG MENGANDUNG EKSTRAK BUAH STROBERI DAN DAUN PEPPERMINT Sopian, Ahmad Sopian; Yunarto, Nanang; Rahimah, Vina Nasriani
PHRASE (Pharmaceutical Science) Journal Vol 5, No 2 (2025): Pharmaceutical Science Journal Vol 5 No 2, 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v5i2.1176

Abstract

ABSTRAKWorld Health Organization (WHO) 2022 memperkirakan penyakit mulut mempengaruhi hampir 3,5 miliar orang diseluruh dunia. Berdasarkan Data RISKESDAS 2018 menunjukkan sebanyak 45% responden mengalami masalah gigi berlubang, 19% masalah gigi hilang atau tanggal sendiri, 10,4% kasus gigi goyah, dan 4,1% gigi ditambal. Data ini menunjukkan bahwa kesadaran masyarakat untuk memeriksa kesehatan gigi dan mulut masih kurang. Sehingga obat kumur dapat digunakan sebagai pencegahan atau pengobatan infeksi tenggorokan. Tujuan penelitian ini untuk mengetahui uji viskositas dan uji stabilitas fisik pada formulasi obat kumur ekstrak buah stroberi dan daun peppermint. Metode penelitian yang digunakan metode penelitian eksperimental. Hasil Penelitian yang diperoleh pada uji viskositas mendapatkan hasil rata-rata yaitu pada formulasi F0 (0%) 3,944 cp, F1 (5%) 4,016 cp, F2 (15%) 4,96 cp dan F3 (25%) 6,412 cp. Uji stabilitas fisik pada formulasi obat kumur ekstrak buah stroberi dan daun peppermint terdiri dari uji organoleptis, uji pH, uji kejernihan, dan uji homogenitas. Dari hasil yang didapatkan menunjukkan bahwa sediaan tidak stabil dan tidak memenuhi syarat standar obat kumur.
Evaluasi Kualitas Dan Kuantitas Penggunaan Antibiotik Pada Penderita Demam Tifoid Di Rawat Inap Rs An-Nisa Tangerang Winarni, Gandes; Putri, Annisa Septyana; Aisyah, Rizqa Nur
PHRASE (Pharmaceutical Science) Journal Vol 5, No 2 (2025): Pharmaceutical Science Journal Vol 5 No 2, 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v5i2.1158

Abstract

Typhoid fever is an infectious disease caused by Salmonella typhi and is still a health problem in Indonesia. The rational use of antibiotics can increase the risk of resistance. This study aims to evaluate the quality and quantity of antibiotic use in typhoid fever patients in the inpatient ward of An-Nisa hospital Tangerang. The method used was descriptive research with retrospective data collection from patient medical records. The sample in the study was 67 patients who met the inclusion criteria. The quality of antibiotic use was analyzed using the Gyssens method based on the Kemenkes of 2013 and Permenkes No. 28 of 2021, while the quality of antibiotic use was analyzed using the ATC/DDD (Defined Daily Dose) method based on theWHO DDD values. The results of the study showed that only 12,72 of antibiotic use was rational (category 0), while the rest was irrational, especially in category IIIB (duration of use too short) by 36,99 and category V (no indication) by 7,51%, category IVC (cheaper antibiotic) by 4,62%, category IIB (inappropriate interval) by 4,05% and category IIC (route of administration) by 2,86%. The most commonly used antibiotic was Cefixime with the highest DD/100 patient-days value of 126,57 and followed by Ceftriaxone with a DDD/100 patient-days value of 75,12. The conclusion of this study shows that there is a need to improve the accuracy of antibiotic administration, especially in duration, dose, and indication of use, to prevent the emergence of antibiotic resistance in the future.
Evaluasi Pemberian Informasi Obat Pada Pasien Tuberkulosis Di Rumah Sakit X Periode April 2025 Dewantoro, Agung; Haryani, Setianti; Rahajeng, Suny Koswara
PHRASE (Pharmaceutical Science) Journal Vol 5, No 2 (2025): Pharmaceutical Science Journal Vol 5 No 2, 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v5i2.1083

Abstract

Drug Information Service (PIO) plays a crucial role in treatment success because accurate and precise information regarding drug use greatly supports the effectiveness of therapy. The objective of this study was to evaluate the provision of drug information to TB patients at Hospital X. Methods: This research used a quantitative descriptive design. Data were collected through a questionnaire distributed to 100 respondents selected using an accidental sampling technique based on predetermined inclusion criteria. Results : Treatment duration 4 months 61 respondents (61%), TB anatomical location pulmonary TB 100 respondents (100%), Treatment phase continuation phase 61 respondents (61%), Most commonly prescribed additional drug group vitamins (45.45%), Most commonly prescribed additional drug type Kurkumax on 40 respondent (40%), The provision of PIO services for TB patients at Hospital X was found to be in good condition (91%). Conclusion: The process of providing anti-tuberculosis drug information at Hospital X is categorized as good.
Profil Pengobatan Dan Efektivitas Obat Tuberkulosis Paru Pada Pasien Tuberkulosis Paru Di Puskesmas Kebayoran Lama Rahajeng, Suny Koswara; Sayyidah, Sayyidah; Fadhilah, Humaira; Dewantoro, Agung; Dewi, Bheta Sari; Ardiansyah, Muhammad Rivan
PHRASE (Pharmaceutical Science) Journal Vol 5, No 2 (2025): Pharmaceutical Science Journal Vol 5 No 2, 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v5i2.1180

Abstract

Pulmonary tuberculosis (TB) is a serious health problem in Indonesia. A treatment profile that meets guidelines and patient compliance is crucial for successful therapy. To determine the treatment profile and effectiveness of TB drugs in patients at the Kebayoran Lama Community Health Center. This descriptive study used secondary data from the medical records of 78 pulmonary TB patients selected by purposive sampling from July to December 2024. Analysis was based on patient characteristics, treatment profiles, and drug effectiveness. The results the majority of patients were aged 17-25 years (38%), female (51%), had a high school education (54%), and worked as private sector workers (27%). In the intensive phase, most patients (72%) weighing 55-70 kg received a regimen of 4 tablets of 4FDC; the continuation phase used 4 tablets of 2FDC. The effectiveness of therapy was demonstrated by 54% of patients with negative AFB conversion accompanied by clinical improvement (reduced cough, increased appetite, decreased shortness of breath). The Conclusion is Pulmonary TB treatment at the Kebayoran Lama Community Health Center is in accordance with national guidelines with weight-based dosage. Regular evaluation is still needed to improve the success of therapy.
Evaluasi Skrining Resep Dan Pelayanan Informasi Obat (PIO) Pasien Rawat Inap Abas, Achmad Fadli; Yulianti, Yulianti; Fauziah, Siti Nur
PHRASE (Pharmaceutical Science) Journal Vol 5, No 2 (2025): Pharmaceutical Science Journal Vol 5 No 2, 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v5i2.1144

Abstract

Clinical pharmacy services are an important component of the health care system that aims to ensure patient safety. Clinical pharmacy services include various activities, including prescription screening and drug information services. This study aims to determine the results of the evaluation of the implementation of prescription screening and drug information services for inpatients at Grha Permata Ibu Hospital. This study is a descriptive observational study conducted with a retrospective data collection method. Data were obtained from inpatient prescriptions received at Grha Permata Ibu Hospital during the period October to December 2024. The samples used in this study amounted to 206 prescription sheets. Based on the results of the study, prescription screening based on administrative completeness has been carried out quite well in accordance with the provisions stated in Permenkes No. 72/2016, with an average achievement of 70.13%. Prescription screening based on pharmaceutical suitability showed excellent results with an average percentage of 93.93%. In addition, drug information services have also been implemented well, with an average achievement of 87.54%.
HUBUNGAN PAPARAN SINAR ULTRAVIOLET DAN PERILAKU PENGGUNAAN SUNSCREEN TOPIKAL SEDIAAN KRIM TERHADAP TERJADINYA SUNBURN PADA PEKERJA LAPANGAN DI TANGERANG SELATAN Kurniawati, Dewi Indah; Adha, Muhammad Zulfikar; Nurihardiyanti, Nurihardiyanti; U. Z., L. M. Zulfahrin; Nahir, Cikal Fiarsi
PHRASE (Pharmaceutical Science) Journal Vol 5, No 2 (2025): Pharmaceutical Science Journal Vol 5 No 2, 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v5i2.1178

Abstract

ABSTRAKKulit merupakan pelindung utama tubuh dari paparan sinar ultraviolet (UV), namun paparan berlebihan dapat menyebabkan sunburn hingga meningkatkan risiko kanker kulit (Watson et al., 2016). Indonesia sebagai negara tropis memiliki intensitas UV yang tinggi, sehingga pekerja lapangan lebih rentan terhadap dampak buruk sinar UV (Wadoe et al., 2019). Sunscreen topikal sediaan krim dapat memberikan perlindungan, tetapi efektivitasnya sangat bergantung pada perilaku penggunaannya. Penelitian ini bertujuan untuk menganalisis hubungan antara paparan sinar ultraviolet dan perilaku penggunaan sunscreen topikal sediaan krim terhadap kejadian sunburn pada pekerja lapangan di Tangerang Selatan. Penelitian ini menggunakan desain kuantitatif dengan pendekatan cross-sectional. Sebanyak 384 responden dipilih menggunakan teknik purposive sampling. Data dikumpulkan melalui kuesioner tertutup dan dianalisis menggunakan uji korelasi Spearman. Hasil penelitian menunjukkan adanya hubungan yang sangat kuat antara paparan sinar UV dengan kejadian sunburn (p 0,001; r = 0,974), serta hubungan negatif yang kuat antara perilaku penggunaan sunscreen dengan kejadian sunburn (p 0,001; r = -0,964). Disimpulkan bahwa paparan UV dan perilaku penggunaan sunscreen memiliki hubungan yang signifikan terhadap kejadian sunburn. Edukasi dan pembentukan kebiasaan protektif dalam penggunaan sunscreen sangat penting, terutama bagi pekerja lapangan.
Identifikasi Tingkat Pengetahuan Masyarakat Tentang Beyond Use Date (Bud) Pada Sediaan Obat Di Rt 002/002 Kelurahan Pinang Kota Tangerang Imansari, Aulia Nadya Rizki; Sayyidah, Sayyidah; Khoirani, Anisah Putri
PHRASE (Pharmaceutical Science) Journal Vol 5, No 2 (2025): Pharmaceutical Science Journal Vol 5 No 2, 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v5i2.1173

Abstract

Public knowledge regarding the expiration of medications after opening or compounding, known as Beyond Use Date (BUD), remains relatively low. BUD plays a crucial role in maintaining the quality, effectiveness, and safety of medications. This study aims to describe the level of public knowledge about BUD in pharmaceutical preparations in RT 002/002, Pinang Subdistrict, Tangerang City. This research employed a descriptive quantitative method with purposive sampling and involved 100 respondents. Data were collected using a questionnaire and analyzed using frequency distribution and percentages. The results showed that most respondents had a moderate level of knowledge (50%), followed by good (24%) and poor (26%) levels. The majority of respondents were aged 17–25 years, female, held a higher education degree, and obtained information about BUD mainly from the internet. It can be concluded that public knowledge regarding BUD still needs improvement, particularly through proper education and information dissemination.
TINGKAT PENGETAHUAN TERHADAP SIKAP PASIEN DIABETES MELLITUS PADA PENGGUNAAN VCO DI PUSKESMAS RAWA MEKAR JAYA Fahriati, Andriyani Rahmah; Rubiana, Amalia Cinta; Oktovina, Magdalena Niken; Hartono, Irwan; Aulia, Gina; Saputri, Dea Maulidi; Fu'adah, Intan Tsamrotul
PHRASE (Pharmaceutical Science) Journal Vol 5, No 2 (2025): Pharmaceutical Science Journal Vol 5 No 2, 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v5i2.1177

Abstract

Diabetes mellitus (DM) is a group of metabolic disorders characterized by hyperglycemia accompanied by abnormal carbohydrate, fat, and protein metabolism. Diabetic foot ulcers are a common complication of diabetes. Diabetic wound care is not solely handled with antibiotics; wound care is mandatory. In diabetic wound care practices, the use of VCO (Virgin Coconut Oil) is often chosen because it maintains wound moisture and is more economical. Knowledge and attitudes are important factors to analyze in supporting therapy. The purpose of this study was to analyze the level of knowledge and attitudes of diabetes mellitus patients regarding the use of VCO at the Rawa Mekar Jaya Community Health Center. This study used a prospective observational research method. Patient samples were selected using a non-random sampling technique (purposive sampling) and must meet the inclusion criteria. The sample consisted of 121 DM patients. The results showed that 78 respondents had good knowledge, of which 62 respondents (51.2%) had a good attitude towards the use of VCO, and 16 respondents (13.2%) showed a poor attitude. Meanwhile, there were 43 respondents with less knowledge, of which 16 respondents (13.2%) had a good attitude and 27 respondents (22.3%) had a less than good attitude. It is known that respondents who have good knowledge, their attitudes towards the use of VCO also increase, as indicated by the results of the bivariate analysis, where the p-value is 0.000 (p 0.05) so it is concluded that there is a relationship between the level of knowledge and the attitudes of diabetes patients on the use of VCO about their treatment.
Analisa Penggunaan Antibiotik Pada Pasien Pneumonia Anak Dan Remaja Di Rs Bhayangkara Lemdiklat Polri Periode Januari-Desember 2024 Nurlela, Nurlela; Dewantoro, Agung; Susanti, Debi; Aulia, Gina
PHRASE (Pharmaceutical Science) Journal Vol 5, No 2 (2025): Pharmaceutical Science Journal Vol 5 No 2, 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v5i2.1174

Abstract

Pneumonia attacks the respiratory tract and is one of the dangerous infections that can potentially cause high mortality rates, especially in children and adolescents. The objective of this study were to analyze the pattern of antibiotics use in pediatric and adolescent pneumonia patients at an inpatient ward, Bhayangkara Lemdiklat Polri Hospital. Methods:This was a descriptive, observational and cross-sectional study. We employed a total sampling method, collecting data from patient medical records retrospectively. Results The findings revealed that most of the patients were toddlers, 0–5 years (43%) Table 1.Length of stay and distribution of pneumonia patients in MMCPS Age Prevalence n(%) Male Patient ratioTime interval Adult N=232 Working daysper dayRange (year) 30%, followed by male gender (53%), with average length of stay from 1 to 7 days (79%). The most frequent comorbidity was anaemia (30%). The antibiotic utilized was predominantly injectables (85%) given as monotherapy 85% and under the class of cephalosporin category (66%). Ceftriaxone (59%).Conclusion: was the most commonly used antibiotic. The findings of this study reveal that the antibiotic prescription for pediatric and adolescent pneumonia patients at Bhayangkara Lemdiklat Polri Hospital are in line with previous research results, where ceftriaxone is the most commonly used as a single-agent injectable antibiotic.
FORMULASI DAN UJI AKTIVITAS ANTIOKSIDAN MASKER GEL PEEL- OFF DARI EKSTRAK BUAH STROBERI (FRAGARIA SP) DENGAN METODE DPPH Utami, Anissa; Pomalingo, Dwina Ramadhani; Bastian, Irvan; Winarni, Gandes; Susanti, Debi; Yuristiawan, Yuristiawan; Alhabzy, Raihan Wisnu
PHRASE (Pharmaceutical Science) Journal Vol 5, No 2 (2025): Pharmaceutical Science Journal Vol 5 No 2, 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v5i2.1152

Abstract

Strawberries (Fragaria sp.) are plants rich in bioactive compounds such as anthocyanins, flavonoids, ellagic acid, and vitamin C, which act as natural antioxidants. This study aimed to formulate and evaluate peel-off gel mask preparations containing strawberry extract and to test their antioxidant activity using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The research was conducted experimentally with three extract concentrations: F1 (2%), F2 (3%), and F3 (4%). The formulations were evaluated through organoleptic testing, homogeneity, pH, drying time, and spreadability. Antioxidant activity was analyzed based on IC50 values. The results showed that all formulations remained stable organoleptically during 4 weeks of storage, were homogeneous, had pH values of 4.72–5.37, drying times of 15–19 minutes, and spreadability between 5.1–6.1 cm. Antioxidant activity tests revealed that F1 had an IC50 value of 63.65 μg/mL, F2 of 57.75 μg/mL, and F3 showed the strongest activity with an IC50 value of 41.77 μg/mL, which is categorized as very strong. In conclusion, the F3 formulation (4%) demonstrated the best physical stability and the highest antioxidant activity.

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