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Dental Journal (Majalah Kedokteran Gigi)
Published by Universitas Airlangga
ISSN : 19783728     EISSN : 24429740     DOI : -
Core Subject : Health,
Dentistry
The Dental Journal (Majalah Kedokteran Gigi) (e-ISSN:2442-9740; p-ISSN:1978-3728) is published by the Faculty of Dental Medicine, Universitas Airlangga. Its diciplinary focus is dental science and dental hygiene. The Dental Journal (Majalah Kedokteran Gigi) is published in English on a quarterly basis with each 50-60 page edition containing between nine and eleven scientific articles on research, study literature and case studies. Contributors to the Dental Journal (Majalah Kedokteran Gigi) included: dental researchers, dental practitioners, lecturers, and students drawn from Indonesia and a wide range of other countries.
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Articles 13 Documents
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Search results for , issue "Vol. 57 No. 2 (2024): June" : 13 Documents clear
The potential active compounds of Jatropha multifida Linn. as an anti-COVID-19 mouthwash: In silico study Effendi, Muhammad Chair; 'Ayun, Aisyah Fitri Qurrata; Putri, Annisa; Kurniawan, Dhiky Dwi; Salsabila, Dinda Aprilla; Malihahsisna, Fahrunisa Tunjung
Dental Journal (Majalah Kedokteran Gigi) Vol. 57 No. 2 (2024): June
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i2.p110-117

Abstract

Background: Povidone-iodine 1% mouthwash is one of the products recommended for preventing and controlling COVID-19 infection in dental procedures. Jatropha multifida Linn. has the same antiseptic effect as povidone-iodine. Purpose: The objective is to determine the effectiveness and interaction effect of secondary metabolites from the latex of Jatropha multifida Linn. and povidone-iodine against the main protease (MPro) SARS-CoV-2 and the SARS-CoV-2 spike protein - ACE2 receptors. Methods: The in silico test was used in this study and carried out using the Molegro Virtual Docker software for molecular docking and BIOVIA Discovery Studio and PyMOL for visualization. Results: The results show that secondary metabolite compounds contained in the latex of Jatropha multifida Linn. have a better effectiveness potential in relation to MPro SARS-CoV-2 and SARS-CoV-2 spike protein - ACE2 receptors than povidone-iodine. Conclusion: The latex of Jatropha multifida Linn. shows potential as a preventive and curative therapy for COVID-19 in the in silico study.
Increased TGF-β1 level after cocoa administration during orthodontics tooth movement in Cavia cobaya Fikri, Annisa Nurul; Farmasyanti, Cendrawasih Andusyana; Pudyani, Pinandi Sri
Dental Journal (Majalah Kedokteran Gigi) Vol. 57 No. 2 (2024): June
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i2.p118-123

Abstract

Background: Orthodontic tooth movement (OTM) is a process of tooth movement in the alveolar socket through a bone remodeling process. Cocoa contains caffeine as a bioactive component. The number of studies on the effects of caffeine on orthodontic tooth movement is rising. Purpose: This study aimed to determine the effect of caffeine in cocoa administration on TGF-β1 levels in the pressure side during orthodontic tooth movement. Methods: Twelve Cavia cobaya were divided into 4 groups: control group (ONC), treatment group with 2.3 mg caffeine in cocoa (OWC1), 3.45 mg dose (OWC2) and 4.6 mg dose (OWC3) (n=3). A NiTi open coil spring with light force was applied to two lower incisors tooth of Cavia cobaya. TGF-β1 level in GCF of the pressure side was analyzed using ELISA on days 0, 1, 7, and 14. Data were analyzed using the Two-way ANOVA test (p<0.05) and the LSD Post-Hoc test. Results: Research indicated improvement of TGF-β1 level from the control group with the least average followed group caffeine in cocoa 2.3 mg (OWC1), 3.45 mg (OWC2), and 4.6 mg (OWC3) (p<0.05). Conclusion: This study confirmed that caffeine in cocoa administration increase TGF-β1 level during orthodontics tooth movement on Cavia cobaya in the pressure side.
Effects of 3% Mobe (Artocarpus lakoocha) leaf extract gel on the post-extraction socket: In-vivo study Hanafiah, Olivia Avriyanti; Hanafiah, Diana Sofiah; Dohude, Gostry Aldica; Satria, Denny; Putri, Maharani Syahnia; Harahap, Nurul Izzatunna Jhirah
Dental Journal (Majalah Kedokteran Gigi) Vol. 57 No. 2 (2024): June
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i2.p102-109

Abstract

Background: Mobe (Artocarpus lakoocha) is recognized for its potential in accelerating wound healing, attributed to its secondary metabolites. However, its impact on hard tissue healing on post- extraction tooth sockets has been underexplored. Purpose: This study aims to analyze the effects of 3% Mobe leaf extract gel on the number of fibroblasts, osteoblasts, osteocytes and post-extraction sockets in Wistar rats. Methods: Thirty-two male Wistar rats had their left mandibular incisors extracted and were divided into eight groups. Mobe leaf extract gel was applied to Group I-IV and Aloclair® gel was applied to Group V-VIII for 14 days, twice a day. Residual socket volume (RSV) and fibroblast counts were measured on days 3, 7, and 14, while osteoblast and osteocyte counts were assessed on days 7, 14, and 28 post extraction. The RSV data were analyzed using repeated measures analysis of variance (ANOVA) and post-hoc least significant difference (LSD) test, while fibroblasts, osteoblasts, and osteocytes counts were analyzed with one-way ANOVA and post-hoc LSD tests. Results: RSV decreased significantly in both groups on day 14 (p=0.001 and p=0.002); however, the RSV was lower on the Mobe group. The fibroblast counts were higher in the Mobe group (p=0.001), and there was a significant difference in the mean number of osteoblasts and osteocytes in the Mobe group (p= 0.043 and p=0.008). Conclusion: The study concludes that 3% Mobe leaf gel extract is better than Aloclair® in accelerating socket healing mainly due to increased proliferation of fibroblasts, osteoblasts, and osteocytes.
Tegillarca granosa shell combination with Vitis vinifera and fluoride in decreasing enamel microporosity Setiawan, Grace Caroline; Tinisia, Adelia; Rahim, Muhammad Galang Adhinata Abdul; Rahmitasari, Fitria; Prananingrum, Widyasri
Dental Journal (Majalah Kedokteran Gigi) Vol. 57 No. 2 (2024): June
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i2.p131-138

Abstract

Background: White spot lesion is a demineralization process indicated by the increased of enamel microporosity. A tegillarca granosa shell contains 98.7% calcium and Vitis vinifera contains phytochemical compounds with fluoride, which has a potential to stimulate remineralization. Purpose: To analyze the Tegillarca granosa shell combination with Vitis vinifera and fluoride in decreasing enamel microporosity. Methods: The cream was prepared by combining 10% and 20% Tegillarca granosa shell with 10 grams of Vitis vinifera extract and 100 mg of fluoride. The cream was tested beforehand for viscocity and pH. Furthermore, 16 premolars were etched and divided into four groups. Group 1 was smeared with placebo (negative control) and Group 2 was smeared with casein phosphopeptide-amorphous calcium phosphate (positive control). The other groups were smeared with cream 10% (Group 3) and 20% (Group 4) Tegillarca granosa shell combination with Vitis vinifera and fluoride. Teeth were treated three times a day for 30 minutes and soaked in artificial saliva. After 14 days, the enamel microporosity was carried out using a scanning electron microscope. The data was analyzed with one-way analysis of variance (ANOVA) test followed by post-hoc least significant difference (LSD). Results: The enamel microporosity showed significant difference between Group 1 and the other groups. There was no significant difference between Groups 2, 3, and 4 (p<0.05). Although there was no significant difference between Group 3 and 4, the lowest one was in Group 4 (p>0.05). Conclusion: The cream, prepared by combining Tegillarca granosa shell with Vitis vinifera and fluoride, is effective in decreasing the enamel microporosity.
Degradation of chitosan–gelatin and chitosan–gelatin–β-tricalcium phosphate scaffolds Putri, Tansza Setiana; Pratiwi, Deviyanti; Margaretta, Dewi Liliany; Tjandrawinata, Rosalina; Shariff, Khairul Anuar
Dental Journal (Majalah Kedokteran Gigi) Vol. 57 No. 2 (2024): June
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i2.p87-90

Abstract

Background: Fabrication of the composite scaffold was carried out by combining chitosan, gelatin, and β-tricalcium phosphate (βTCP) derived from limestone. The extraction of βTCP was based on the abundance of limestone containing calcium carbonate, which can be a source of βTCP synthesis. Purpose: This study evaluates the degradation of the combination of chitosan–gelatin (ChG) and chitosan–gelatin–βTCP (ChG-βTCP) composite scaffolds. Methods: The freeze-drying method was used to obtain the composite scaffold, which was a mixture of chitosan, gelatin, and βTCP. Degradation was measured by immersing the samples in a simulated body fluid solution at 37°C for 3, 7, 14, and 21 days. For statistical analysis, one-way analysis of variance (ANOVA) and post hoc Fisher's least significant difference were performed. Results: The ChG scaffold shows better degradability than the ChG-βTCP scaffold. The ChG scaffold shows higher weight degradation than the ChG-βTCP scaffold up to 21 days. Conclusion: In conclusion, the scaffold containing βTCP has lower degradation than the ChG scaffold.
Bone formation and mineralization around the implant in osteoporotic animal models enhanced by mesenchymal stem cells Hendrijantini, Nike; Kuntjoro, Mefina; Agustono, Bambang; Ari, Muhammad Dimas Aditya; Kurdi, Abil; Mundiratri, Karina; Prasetyo, Eric Priyo; Hong, Guang
Dental Journal (Majalah Kedokteran Gigi) Vol. 57 No. 2 (2024): June
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i2.p91-96

Abstract

Background: Poor bone quality, sometimes caused by osteoporosis, can lead to dental implant failure. Human umbilical cord mesenchymal stem cells (hUCMSCs) can differentiate into osteoblasts and offer an alternative therapy for poor bone conditions. Purpose: This study aims to evaluate the effect of hUCMSCs induction on the extent of osseointegration by the new bone formation area of dental implants in osteoporotic animal models. Methods: The samples were divided into two groups, i.e., control and induced hUCMSCs groups at different times. An ovariectomy was performed to assess the osteoporosis condition. The control group was injected using gelatin, and the treatment group was administered hUCMSCs. Terminations were conducted at 2 and 4 weeks, respectively. The collected samples were then subjected to histological examination to analyze new bone formation and its proportion. In addition, alkaline phosphatase staining was also performed to evaluate the mineralization area. The data was analyzed using the one-way analysis of variance (ANOVA). Results: Both for new bone formation area as well as the proportion of new bone, it was observed that the best results were in the group with induction of hUCMSCs at 2 weeks. Alkaline phosphatase staining also confirmed that the highest mineralization was observed in the same group. Conclusion: hUCMSCs induced new bone formation in the implant placement in osteoporotic animal models.
Endodontic treatment of severely curved root canals – A case series Rosselle, Veronica Regina; Ongkowijoyo, Cendranata Wibawa; Setyabudi
Dental Journal (Majalah Kedokteran Gigi) Vol. 57 No. 2 (2024): June
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i2.p145-151

Abstract

Background: It is not uncommon for a dentist to encounter endodontic cases of severely curved root canals. Performing endodontic treatment on severely curved root canals can be a daunting task due to the notable risk of creating an iatrogenic error including ledge, perforation, or even instrument separation. Therefore, radiograph image analysis, proper endodontic treatment planning, selection of appropriate instruments and technique is essential to ensure success in endodontic treatment of severely curved root canals. Purpose: This case series aims to elaborate the instruments and technique to safely negotiate, clean, shape, and seal root canals with severe curvature. Cases: Three patients came to Universitas Airlangga Dental Hospital due to a severe toothache. After anamnesis and examination, diagnosis was established, and endodontic treatment was deemed necessary. During radiographic image analysis, it is visible that the root canal had a severe curvature. Case Managements: Access opening was performed to allow a straight-line access, orifices were preflared, root canals were negotiated, and glide path was established. Then, shaping, cleaning, and sealing can be performed conveniently until the root canal terminus. Subsequently, coronal restoration was fabricated to restore function and esthetics. Conclusion: With proper knowledge, case analysis, appropriate instruments and techniques, severely curved root canals can be safely and predictably negotiated, cleaned, shaped, and sealed.
The role of fibrinogen-like protein 1 in immune escape and tumor growth mechanism of Warthin's tumor Arifin, Grandissyaikhu Kamila; Indriana, Tecky; Kosasih, Jane; Dharmayanti, Agustin Wulan Suci; Syafriadi, Mei
Dental Journal (Majalah Kedokteran Gigi) Vol. 57 No. 2 (2024): June
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i2.p139-144

Abstract

Background: One of the benign tumors of the salivary glands is Warthin's Tumor (WT), which consists of cystic bilayer papillary epithelial cells accompanied by the presence of a lymphoid stroma. Several cases have been reported to turn malignant. One of the markers developed to identify tumor proteins is fibrinogen-like protein 1 (FGL1). Along with lymphocyte-activation gene 3 (LAG-3), FGL1 establishes an immune checkpoint pathway that plays a role in the mechanism of tumor immune escape. Not much has been reported regarding FGL1 expression in WT, but some studies have reported that its expression is associated with tumor growth. Purpose: This study aims to analyze the location of FGL1 expression in WT and its relation to the mechanism of tumor immune release through the interaction between FGL1 and LAG-3. Methods: Cases of WT (n = 11) and breast cancer (n = 1) were used as positive controls. All cases were stained with hematoxylin-eosin and Recombinant Anti-FGL1 antibody. The FGL1 expression was observed in the cell membrane, cytoplasm, and lymphoid stroma. The results are presented in the form of figures. Results: All cases of WT expressed FGL1 in the cell membrane, cytoplasm, and lymphoid stroma. Its expression in the cell membrane and cytoplasm is possibly related to the process of tumorigenesis and the increasing size of the lesion. Additionally, its expression is seen in the lymphoid stroma, which is closely related to immune escape by inhibiting lymphocytes against tumor cells. Conclusion: Warthin's tumor cells express FGL1, and this expression plays a role in tumor immune escape mechanisms and tumor growth.
Comparative evaluation of stress generation in primary teeth restored with zirconia and BioFlx crowns: A finite element analysis Deolikar, Sayali; Rathi, Nilesh; Mehta, Vini
Dental Journal (Majalah Kedokteran Gigi) Vol. 57 No. 2 (2024): June
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i2.p80-86

Abstract

Background: Maintaining the functional integrity of primary teeth is important, as these teeth are integral in vital functions such as mastication, speech development, and space maintenance for permanent teeth; hence, premature loss of primary teeth can affect a child's quality of life. Various restorative materials are available to restore the function of grossly decayed teeth. Stainless steel crowns and zirconia crowns are widely used in pediatric dentistry; however, there are certain disadvantages associated with these materials. Recently introduced BioFlx crowns provide acceptable esthetics with a conservative approach. Nevertheless, there is a lack of evidence regarding their strength and clinical acceptability. Finite element analysis measures the physical response of teeth and assesses the stress generation, which is important to estimate the integrity of the restorations and crowns. Purpose: The aim of this in vitro study was to evaluate and compare stress generation in primary teeth restored with zirconia and BioFlx crowns using finite element analysis. Methods: Models of extracted teeth restored with zirconia and BioFlx crowns were used for the study. The finite element analysis of these models was carried out through Analysis of Systems (ANSYS) software. The models were subjected to a simulated occlusal loading force of 245 N. Results: Von Mises stress generated in BioFlx crowns along with underlying dentin was much less compared to that which was generated in zirconia crowns. Conclusion: Restoring the functional integrity of carious teeth is essential. BioFlx crowns can be used as full coverage restorations and can be a suitable alternative to zirconia crowns and traditional stainless steel crowns.
Length of cranial base and total face height in cephalograms for sex estimation in Indonesia Ramadhani, Nabila Almira; Widyaningrum, Rini; Gracea, Rellyca Sola; Ningtyas, Aini Hasibah; Mudjosemedi, Munakhir
Dental Journal (Majalah Kedokteran Gigi) Vol. 57 No. 2 (2024): June
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i2.p97-101

Abstract

Background: Sex estimation is the first step in identifying bodies following disasters or accidents. Craniometric analysis of lateral cephalograms can be used in the process. Among the measurements that can be used are the length of cranial base, determined by Basion–Nasion (Ba-N) length, and the total face height, determined by the Nasion–Menton (N-M) length, which can highlight significant differences between men and women. Purpose: This study aimed to determine the differences in length of cranial base and total face height measurements between men and women and to demonstrate how these two measurements can be used for sex estimation in the Indonesian population. Methods: This cross-sectional study employed a patient database from the dental hospital of Universitas Gadjah Mada. The study sample consisted of 116 cephalograms taken of 58 men and 58 women aged 20–40 years. The linear measurements were taken using EzDent-I Vatech software. Results: The mean cranial base length measurements in the men and women groups were 103.83 ± 4.37 and 96.01 ± 3.80 mm, respectively, whereas the total face height measurements were 121.03 ± 7.26 and 111.23 ± 5.09 mm, respectively. The Mann–Whitney U-Test revealed a significant difference (p < 0.05) between the groups. Logistic regression showed that the two measurements can be used to form an equation for sex estimation with an accuracy of 88.8%. Conclusion: Length of cranial base (Ba-N) and total face height (N-M) measurements from lateral cephalograms can accurately be used for sex estimation. Further research among specific populations is required to develop accurate methods for sex estimation employing morphometric examination on radiographs.

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