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All Journal Biology, Medicine, & Natural Product Chemistry Pharmascience IDJP (Indonesian Journal of Pharmaceutics) SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Pharmasipha Majalah Farmasetika Medfarm: Jurnal Farmasi dan Kesehatan Jurnal Farmasi Etam Jurnal Pengabdian Masyarakat Tjut Nyak Dhien Journal of Innovation Research and Knowledge Pharmaceutical Sciences and Research (PSR) Journal of Biotechnology and Natural Science Sciences of Pharmacy Media Farmasi Camellia Jurnal Pengabdian Kesehatan Jurnal Sains dan Kesehatan
Maria Elvina Tresia Butar-Butar
Departemen Farmasetika Dan Teknologi Formulasi, Fakultas Farmasi, Universitas Padjadjaran, Jalan Raya Bandung Sumedang KM 21 Jatinangor, Jatinangor 45363, Jawa Barat, Indonesia
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Antihyperuricemic Activity of Tahongai (Kleinhovia hospita L.) Leaf Infusion in Mice (Mus musculus L.) Sianturi, Sister; Sinaga, Clara Ritwany; Leswana, Nurillahi Febria; Butar-Butar, Maria Elvina Tresia; Simanullang, Raymon
Journal of Biotechnology and Natural Science Vol. 5 No. 2 (2025): December
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/jbns.v5i2.14723

Abstract

Tahongai (Kleinhovia hospita L.) is recognized as a traditional medicinal plant originating from East Kalimantan. This species possesses various bioactive properties that contribute to health benefits, particularly from its leaves, which contain active compounds such as flavonoids, alkaloids, saponins, and terpenoids. These bioactive constituents have been reported to exhibit anti-hyperuricemic properties. This study aimed to evaluate the anti-hyperuricemic activity of K. hospita leaf infusion in hyperuricemic mice (Mus musculus L.), which were induced using chicken liver juice. The test material used was an infusion prepared from K. hospita leaves. The experimental design consisted of five treatment groups: a positive control group receiving allopurinol, a negative control group receiving distilled water, and three treatment groups administered K. hospita leaf infusion at varying concentrations of P1=15%, P2=30%, and P3=60%. The results indicated that the highest mean reduction in uric acid levels was observed in the P2 group, which received a 30% concentration of K. hospita leaf infusion, with an average percentage decrease of 19.12%. However, statistical analysis using One-Way ANOVA revealed a p-value greater than 0.05, indicating that there was no significant difference in uric acid reduction among the treatment groups.
Relationship of Knowledge and Motivation with Compliance in Taking Anti-Tuberculosis Drugs in TB Patients at North Bontang Health Center 1 husna, Husna husna; Leswana, Nurillahi Febria; Butar-Butar, Maria Elvina Tresia
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 2 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i2.619

Abstract

Tuberculosis (TB) treatment requires six months of continuous Anti-Tuberculosis Drug (OAT) therapy; non-compliance leads to treatment failure and Multi-Drug Resistant TB. This study aimed to analyze the relationship between patient knowledge and motivation with medication compliance among TB patients at the North Bontang Health Center 1, Indonesia. This cross-sectional study involved tuberculosis patients at North Bontang 1 Health Center. From a total registered population of 325 patients, a strict purposive sampling technique was applied based on inclusion and exclusion criteria, resulting in 30 eligible patients who participated in this study during the period of December 2024 to January 2025. Data on knowledge and motivation were collected using structured questionnaires; compliance was determined via triangulation (interviews, TB Form 01, PMO). Bivariate analysis used the Fisher's Exact Test (n=30). Results showed the majority demonstrated good knowledge (83.3%) and high motivation (90.0%), resulting in a high overall compliance rate (93.3%). Statistical analysis revealed a significant relationship between knowledge and compliance (p=0.006). No statistically significant relationship was found between motivation and compliance (p=0.193), likely due to data homogeneity
Pemberdayaan masyarakat desa sungai bawang melalui pelatihan diversifikasi olahan lele dan pemasaran digital Muh. Taufiqurrahman; Maria Elvina Tresia Butar-Butar; Remita Ully Hutagalung; Maria Floriana Ping; Nurillahi Febria Leswana; Angel Natalia Nainggolan; Falen Sindi Ayugistia
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 9, No 3 (2025): May
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v9i3.31056

Abstract

AbstrakDesa Budaya Sungai Bawang merupakan salah satu desa binaan STIKES Dirgahayu Samarinda yang memiliki potensi besar dalam pengembangan program ketahanan pangan dan peningkatan derajat kesehatan masyarakat. Pada tahun 2024, melalui anggaran desa, masyarakat menerima bantuan bibit ikan lele sebagai bentuk inisiasi budidaya perikanan di pekarangan rumah. Melihat potensi ini, kegiatan pengabdian kepada masyarakat dilakukan untuk mendukung hilirisasi hasil budidaya ikan lele dalam bentuk produk olahan pangan yang bernilai ekonomi tinggi serta berdaya saing pasar. Kegiatan pengabdian dilaksanakan melalui tiga tahapan utama, yaitu penyuluhan, pelatihan, dan pendampingan izin edar Pangan Industri Rumah Tangga (PIRT). Penyuluhan diberikan dengan metode presentasi dan diskusi interaktif, yang membahas pentingnya diversifikasi produk olahan ikan dan pembentukan kelompok usaha. Pelatihan dilakukan secara langsung dengan metode demonstrasi pembuatan produk berupa nugget dan sosis lele, melibatkan 30 peserta dari anggota PKK. Selanjutnya, dilakukan pendampingan teknis dalam proses pengurusan izin edar PIRT agar produk dapat dipasarkan secara legal dan luas. Hasil kegiatan menunjukkan adanya peningkatan pengetahuan dan keterampilan peserta dalam mengolah hasil budidaya ikan. Kegiatan ini juga mendorong terbentuknya satu kelompok usaha baru yang siap memproduksi pangan olahan secara mandiri. Dampak jangka pendek berupa peningkatan partisipasi masyarakat dalam kegiatan ekonomi produktif, sedangkan dampak jangka panjang diharapkan berupa peningkatan pendapatan rumah tangga dan kemandirian ekonomi berbasis potensi lokal. Kata kunci: pelatihan;  digitalisasi marketing; ikan lele. AbstractSungai Bawang Cultural Village is one of the villages fostered by STIKES Dirgahayu Samarinda which has great potential in developing food security programs and improving public health. In 2024, through the village budget, the community received assistance in the form of catfish seeds as a form of initiation of fish farming in their yards. Seeing this potential, community service activities were carried out to support the downstreaming of catfish cultivation results in the form of processed food products that have high economic value and are competitive in the market. Community service activities were carried out through three main stages, namely counseling, training, and assistance for the distribution permit for Household Industry Food (PIRT). Counseling was provided using presentation and interactive discussion methods, which discussed the importance of diversifying processed fish products and forming business groups. The training was carried out directly using a demonstration method for making products in the form of catfish nuggets and sausages, involving 30 participants from PKK members. Furthermore, technical assistance was provided in the process of managing the PIRT distribution permit so that the products could be marketed legally and widely. The results of the activities showed an increase in the knowledge and skills of participants in processing fish farming products. This activity also encourages the formation of a new business group that is ready to produce processed food independently. The short-term impact is in the form of increasing community participation in productive economic activities, while the long-term impact is expected to be in the form of increasing household income and economic independence based on local potential. Keywords: training; digital marketing; catfish.
PERBANDINGAN EFEKTIVITAS BIOADSORBEN KULIT PISANG AMBON DAN KULIT SUKUN TERHADAP LOGAM Pb(II) PADA LIMBAH CAIR LABORATORIUM FARMASI DENGAN METODE SPEKTROFOTOMETRI UV-VISIBLE Desti Natalia Lantika T; Nurillahi Febria Leswana; Maria Elvina Tresia Butar-Butar
Jurnal Farmasi Etam (JFE) Vol 5 No 2 (2025): Desember
Publisher : Unit Penelitian dan Pengabdian Kepada Masyarakat (UPPM) STIKES Dirgahayu Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52841/jfe.v5i2.848

Abstract

Kegiatan manusia mengakibatkan pencemaran limbah logam berat ke ling- kungan dalam aneka macam bentuk, termasuk limbah kegiatan industri, limbah laboratorium, pembuangan transportasi, limbah kota, kawasan pembuangan sampah, limbah pertambangan, dan pelapisan listrik. Tujuan dari penelitian ini adalah menentukan perbandingan efektivitas bioadsorbeni serbuk kulit buah pisang ambon dan serbuk kulit buah sukun terdapat logam Pb limbah cair laboratorium farmasi dan mengetahui perbandingan kemampuan bioadsorben serbuk kulit buah pisang ambon dan serbuk kulit buah sukun terhadap logam Pb limbah cair laboratorium farmasi. Penelitian ini menggunakan metode Spektrofotometri UV-Visible. Berdasarkan kurva hubungan absorbansi terhadap waktu diperoleh kondisi yang stabil yaitu pH 4 pada menit ke 45 sampai 60. Pada penelitian ini menunjukkan pisang ambon waktu optimum kulit pisang ambon adalah 60 menit pada 23,4% dan efektivitas dari pisang ambon yaitu sebesar 29,7% dengan kondisi pH optimum pada pH 5. Sedangkan kulit sukun pada waktu optimum 60 menit 27,4%. Dari data didapat dikatakan bahwa bioadsroben kulit sukun memiliki efektivitas yang cukup baik dalam proses penyerapan Pb dengan nilai efektivitas sebesar 79,6%. sedangkan sukun dengan kondisi optimum pH 5, waktu kontak 60 menit dan massa 125 mg semakin bertambahnya bobot maka semakin menurunnya absorbansi dari limbah. Kata Kunci : Kulit Pisang Ambon, Kulit Sukun, Timbal Pb (II), Limbah Laboratorium Farmasi
Formulasi dan Evaluasi Sleeping Mask Ekstrak Biji Kurma Ajwa (Phoenix Dactylifera L) dan Biji Kopi Robusta (Coffea Robusta L) dengan Variasi Konsentrasi Karbopol 940 sebagai Gelling Agent Dari, Dewi Wulan; Tresia Butar-Butar, Maria Elvina; Febria Leswana, Nurillahi
Majalah Farmasetika Vol. 11 No. 2, Tahun 2026 (In Press)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/mfarmasetika.v11i2.66017

Abstract

Sleeping mask merupakan skincare yang digunakan dimalam hari saat sebelum tidur. Kandungan antioksidan pada bahan alami dapat menghambat radikal bebas mencegah penuaan dini. Didalam biji kurma ajwa (Phoenix dactylifera L.) terdapat kandungan flavonoid sebagai antioksidan yang memiliki fungsi untuk memperbaiki sel-sel yang rusak. Kopi robusta (Coffea robusta L.) memiliki kandungan kafein sebagai antioksidan dan mempunyai aroma khas kopi yang menenangkan sehingga kedua bahan alam tersebut cocok dikombinasikan. Dalam penelitian ini diformulasikan karbopol 940 sebagai gelling agent. Penelitian ini bertujuan untuk mengetahui evaluasi sifat fisik pada sediaan gel sleeping mask ekstrak biji kurma ajwa dan biji kopi robusta dengan variasi konsentrasi terbaik gelling agent. Penelitian ini menggunakan metode eksperimen. Biji kurma ajwa dan kopi robusta diekstraksi dengan cara maserasi dalam etanol 96%. Penelitian ini menggunakan 3 variasi konsentrasi karbopol 940 yaitu F1 (0,5%), F2 (1%), dan F3 (1,5%). Uji evaluasi sifat fisik yang dilakukan meliputi uji organoleptik, homogenitas, daya sebar, daya lekat, uji pH, viskositas, dan uji stabilitas fisik. Hasil penelitian menunjukkan ketiga variasi karbopol 940 memenuhi semua kriteria uji evaluasi fisik dan hasil uji One Way ANOVA pada daya lekat, pH, dan viskositas menunjukan perbedaan yang signifikan antara kelompok karena nilai signifikasi lebih kecil dari taraf signifikansi 0,05.
Co-Authors Agnes Elisa Agus, Adhe Septa Ryant Andrian Fernandes, Andrian Angel Natalia Nainggolan Anis Yohana Chaerunisaa, Anis Yohana Awan, Kevin Imanuel Clara Ritawany Sinaga Dari, Dewi Wulan Desti Natalia Lantika T Dwi Retno Sari, Dwi Retno Fahrudin Gozali Fajar Falen Sindi Ayugistia Hayatus Sa'adah Hestiary Ratih Husna, Husna Husna Jenly Adinata Luhat, Martin Gilbert Morijan, Risky asrina Nasrul Wathoni Nurillahi Febria Leswana Pahlevi, Muhamad Reza Pijaryani, Indria Ping, Maria Floriana Pratama, Reza Prehatin, Chrisbaningrum Remita Ully Hutagalung Rizki Maharani Roni, Asep Ryan, Adhe Septa Sagita, Novaliana Devianti Selvina, Selvina Septa Ryant Agus, Adhe Simanjuntak, Servis Simanullang, Raymon Sinaga, Clara Ritwany Sister Sianturi Sriminarty Tambing Taufiqurrahman, Muh Tiara, Anastasia Tokan, Santa Eufrasia Carolin Yoga Windhu Wardhana Yoga Windu Wardhana Yulia Sukawaty Zaelani, Diki