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All Journal Jurnal Ilmiah Farmasi Indonesian Journal of Pharmaceutical Science and Technology Nurani: Jurnal Kajian Syariah dan Masyarakat Jurnal Kesehatan Bakti Tunas Husada Syntax Literate: Jurnal Ilmiah Indonesia SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Journal of Pharmacopolium PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) MEDIA INFORMASI JURNAL FARMASI GALENIKA AMALIAH: JURNAL PENGABDIAN KEPADA MASYARAKAT Stilistika: Jurnal Pendidikan Bahasa dan Sastra Lumbung Farmasi : Jurnal Ilmu Kefarmasian Borneo Journal Of Pharmascientech International Journal of Research in Community Services Jurnal Abdimas Kartika Wijayakusuma Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Batara Wisnu : Indonesian Journal of Community Services Jurnal Farmasi Indonesia Edukasi Masyarakat Sehat Sejahtera (EMaSS) Karya Kesehatan Siwalima Jurnal Pengabdian Masyarakat (Jupemas) Jurnal Akuntansi, Perpajakan dan Auditing THORIQOTUNA: Jurnal Pendidikan Islam

Susilawati, Elis

Universitas Bhakti Kencana

Author-ID : 1082825

Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Pengaruh Diet Tinggi Fruktosa Terhadap Resistensi Insulin Pada Tikus Jantan Putih (Rattus norvegicus) Galur Wistar Susilawati, Elis; Levita, Jutti; Susilawati, Yasmiwar; Sumiwi, Sri Adi
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 16 No 2 (2024): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v16i2.274

High fructose intake can cause metabolic disturbances leading to the onset of metabolic syndrome and type 2 diabetes mellitus. This study will present some of the effects of fructose consumption. This study aims to model the animal test by giving 60% fructose to insulin resistance. The research method used 8 male white rats of Wistar strain which were grouped into 2 groups, namely normal group and 60% fructose group. Parameters observed on body weight, blood glucose levels, Insulin Tolerance Test Constant (ITTC), adiponectin levels and TNF-α levels and adipose tissue histology. The results showed that the administration of 60% fructose for 60 days showed a difference for blood glucose levels starting on days 30-60, ITTC values of the fructose group were smaller than the normal group, adiponectin levels of the fructose group were smaller than the normal group, while TNF-α levels of the fructose group were greater than the normal group and there was an enlargement of the diameter of white adipose tissue and a reduction in brown adipose in the fructose group, but there was no difference in body weight. It can be concluded that the administration of 60% fructose for 60 days can be used as modeling of insulin resistance test animals.

Aktivitas Ekstrak Etanol Daun Kate Mas (Euphorbia heterophylla Desf.) pada Tikus Putih Jantan Galur Wistar yang Resistensi Insulin Susilawati, Elis; Syihabbudin, Nazar; Kaniawati, Marita
Indonesian Journal of Pharmaceutical Science and Technology Vol 12 (2025): Vol. 12 Suppl. 2 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12s2.59555

Euphorbia heterophylla. Desf (kate mas) menunjukkan aktivitas penurunan glukosa darah, serta memiliki sifat antioksidan dan antiinflamasi. Penelitian ini bertujuan untuk mengeksplorasi potensi ekstrak etanol daun Euphorbia heterophylla Desf (EEH) sebagai anti resistensi insulin dalam pengelolaan diabetes mellitus tipe 2 (DMT2). Tujuan penelitian ini untuk mengetahui efek dan dosis efektif Ekstrak Etanol Daun Kate Mas (Euphorbia heterophylla Desf), disingkat EEH, terhadap tikus yang diinduksi makanan tinggi karbohidrat, lemak, dan fruktosa 30%. Metode penelitian dilakukan secara in vivo menggunakan 24 tikus jantan putih galur wistar yang dibagi menjadi 6 kelompok, yaitu kelompok kontrol normal, kontrol negatif, kontrol positif, EEH 50 mg/KgBB, 100 mg/KgBB, dan 200 mg/Kg BB dengan melakukan tes kadar glukosa darah (KGD), pengukuran konstanta tes toleransi insulin (KTTI) dan histopatologi sel pankreas. Hasil penelitian menunjukkan bahwa EEH pada semua kelompok dapat menurunkan KGD (92,25 mg/dL±7,04 untuk 50 mg/KgBB; 99,75 mg/dL±13,57 untuk 100 mg/Kg BB; 117,00 mg/dL ±0,85 untuk 200 mg/Kg BB; dan 89,00 mg/dL ±5,34 untuk metformin) dibandingkan dengan kelompok kontrol negatif (132,00 mg/dL ±7,16). EEH 50 mg/Kg BB secara signifikan dapat meningkatkan sensitivitas insulin (3,95±0,53) dibandingkan dengan kelompok negatif (1,24±0,98). Hasil histologi pankreas menunjukan EEH pada semua kelompok uji dapat menurunkan jumlah nekrosis sel pankreas dibandingkan dengan kelompok kontrol negatif. Kesimpulannya, EEH memiliki potensi untuk dieksplorasi lebih lanjut untuk aktivitas dalam meningkatkan sensitivitas insulin.

AKTIVITAS ANTIINFLAMASI DAN ANTIOKSIDAN KOMBINASI EKSTRAK ETANOL BUNGA ROSELA (Hibiscus sabdariffa) DAN DAUN PEGAGAN (Centella asiatica) PADA TIKUS WISTAR JANTAN DENGAN OBESITAS Kaniawati, Marita; Sulaeman, Agus; Susilawati, Elis; Zinan, Daula Zahra; Irviansyah, Cepy Okta
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 10 No 1 (2025): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v10i1.2323

One of the triggers for obesity is high fat and high carbohydrates foods which increase Free Fatty Acid (FFA) and Reactive Oxygen Species (ROS), that trigger oxidative stress and chronic inflammation, which play a role in various degenerative diseases. This study aims to determine the potency and effective dose of ethanol extract of roselle flowers (Hibiscus sabdariffa) and gotu kola leaves (Centella asiatica) combination on oxidative stress (represented by Malondialdehyde or MDA) and its effect on inflammation (represented by Tumor Necrosis Factor-α or TNF-α). This research used in vivo experimental preventive method using 35 mice which were divided into normal group, induction group, comparison group curcumin 1.8 mg/kgBW, test group 1 EDP 200 mg/kgBW, test group 2 EBR 250 mg/kgBW, test group 3 EBRDP 125:200 mg/kgBW and test group 4 EBRDP 250:100 mg/kgBW. MDA levels were measured using UV-Vis spectrophotometry at 532 nm and TNF-α levels were measured using an ELISA kit on the 60th day. The results showed a decrease in blood MDA levels in EDP 200 mg/kgBW, EBR 250 mg/kgBW and EBRDP 250: 100 mg/kgBW and in liver MDA levels in EDP 200 mg/kgBW and EBRDP 250:100 mg/kgBW. The study also showed decreasing TNF-α levels in EDP 200 mg/kg BW, EBR 250 mg/kgBW, and the combination of EBRDP dose 125:200 mg/kgBW. In conclusion, the combination of EBRDP dose 250:100 mg/kgBW is the most effective dose in reducing MDA levels. The combination of EBRDP dose 125:200 mg/kgBW is the most effective dose in suppressing TNF-α levels.

Aktivitas Antidislipidemia Rebusan Daun Mangga Kultivar Manalagi (Mangifera indica L. Var. Manalagi) Sulaeman, Agus; Susilawati, Elis; Aolina, Shelin
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 14 No 2 (2022): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Abstract: Dyslipidemia is characterized by changes in lipid levels in plasma, a common indicator that is prone to the risk of cardiovascular disease. Plants that are suspected to have antidislipidemia activity, one of which is mango leaves. This study aimed to determine the effective dose in a decoction of mango manalagi leaves (Mangifera indica L. var. Manalagi) in decreasing levels of total cholesterol, triglycerides, LDL, and increasing HDL levels in high-fat feed-induced rats and propylthiouracil for 28 days. This research method was carried out preventively using 30 Wistar strain male rats which were grouped into 6 groups, namely negative control, positive control, comparison control (simvastatin 1.8mg/Kg BW), and a decoction test of manalagi mango leaves at a dose of 200, 400, 800 mg/kg BW. The parameters of the observed lipid profile are determined enzymatically using the micro lab. The results of the study on total cholesterol levels, showed the largest decreasing in the 200mg/kg BW dose group by 31.29%, in triglyceride levels the largest decreasing was found in the 400mg/kg BW dose group by 40.59%, in LDL levels the largest decreasing was found in the 200 mg/kg BW dose group by 48.03%, and in HDL levels there was the largest increasing in dose 800mg /kg BW of 97.40%. This study concludes that manalagi mango leaf decoction can be an antidyslipidemia in decreasing total cholesterol, triglyceride, and LDL levels as well as increasing HDL levels, with an effective dose of 200mg/ kg BW.

Potensi Penghambatan Enzim Αlfa-Glukosidase dan Tes Toleransi Glukosa Oral (TTGO) Ektrak Daun Dadap Serep (Erythrina subumbrans (Hassk) Merr.): Susilawati, Elis; Astuti, Ayu Dwi; Sulaeman, Agus
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 15 No 1 (2023): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Abstract: Spare dadap plants contain flavonoids that can potentially lower glucose levels in the blood and reduce glucose absorption in the intestine. The purpose of the study was to determine the inhibitory activity of the α-glucosidase enzyme and the effect of giving Spare Dadap Leaf Ethanol Extract (EEDDS) on blood glucose levels of male white Wistar rats and its effective dose. The research method used the in vitro method with inhibition of α-glucosidase enzyme and the in vivo method Glucose Tolerance Test (TTGO) with amylum manihot induction using 25 rats divided into 5 groups with EEDDS doses of 100, 200, and 400 mg / kg BB, then measured blood glucose levels for 120 minutes. The results of the EEDDS α-glucosidase enzyme inhibition study showed the best % inhibition value of 41.81% at 100 ppm and the lowest % inhibition value at 10 ppm, which was 13.33% with an IC50 value of 146.30 ppm, which was included in the weak category in inhibiting α-glucosidase. The results of TTGO research induced amylum manihot, EEDDS 400 mg / KgBW have a significant effect on reducing blood glucose levels in the T60 to T120 range. The conclusion in this study is that spare dadap leaf ethanol extract has potential as an antihyperglycemic both in vitro and in vivo.

Realisme Sosial dalam Potret Seorang Komunis Karya Sabar Anantaguna Susilawati, Elis; Rahayu, Ismah; Salsabila, Akifah Humaira; Bahtiar, Ahmad
Stilistika: Jurnal Pendidikan Bahasa dan Sastra Vol 15 No 1 (2022)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/st.v15i1.8706

Social Realism in Potret Seorang Komunis by Sabar AnantagunaÂ ABSTRAKPuisi Potret Seorang Komunis karya Sabar Anantaguna telah mendapatkan bentuk dan pengucapan yang tepat sehingga menjadi prestasi yang bagus dalam sastra realisme sosialis karena tidak terlepas dari latar belakang dan ideologi pengarang yang merupakan bagian dari Lekra. Penelitian ini bertujuan untuk membahas prinsip realisme sosial yang menjadi pandangan para pengarang Lekra. Metode analisis yang digunakan dalam penelitian ini adalah metode penelitian deskriptif kualitatif dan teknik interpretatif. Dalam pengolahan data dilakukan tahap pendeskripsian dan penganalisisan. Penelitian ini menggunakan teori sosiologi sastra, teori realisme sosial dan teori struktural. Hasil dari penelitian Realisme Sosial dalam Potret Seorang Komunis Karya sabar Anantaguna terbukti bahwa prinsip realisme sosial yang menjadi pandangan para pengarang Lekra yaitu Lekra memiliki berbagai macam cara yang dilakukan dengan maksud mempertahankan kekuatan komunis, salah satunya melakukan berbagai teror kepada setiap golongan untuk bergabung dengan Lekra.Â Kata kunci: komunis, puisi, realisme sosial, lekraÂ ABSTRACTThe poem portrait of a communist written by Sabar Anantaguna has obtained the right form and pronunciation. Therefore, it becomes a good achievement in social realism literature because it cannot be separated from the author background and ideology who is part of Lekra This study aims to discuss the social realism principles that becomes the views of the Lekra authors. The method used in this research is descriptif qualitative and note taking techniques. In processing data, the stages of description and data analysis are carried out. This study used sociology literature research, realism social teory and structural teory. The result of the research on social realism in the portrait of a communist by Sabar Anantaguna proves that realism social principle becomes the views of Lekra author, namely Lekra, had various ways that were carried out to maintain communist power, one of which carried out various terrors to every groups in order to join LekraKeyword: communist, poem, social realism, Lekra

Gel Formulations of Guava Leaves (Psidium Guajava L) Leaves Ethanol Extract As a Wound Healing Of Burns in Rabbits Sutrisno, Entris; Susilawati, Elis; Herdiana, Geralda Bintang; Noviyanti, Eva
International Journal of Research in Community Services Vol. 5 No. 2 (2024)
Publisher : Research Collaboration Community (Rescollacom)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46336/ijrcs.v5i2.626

The ethanol extract of guava leaves (Psidium guajava L) in previous studies was known to have antiburn, antiinflammatory, antidiarrhea and antibacterial activity. The preparations made are gel preparations which are preferred by the public. The purpose of this study was to determine the activity of guava leaf ethanol extract gel and its effective concentration in healing burns in rabbits. The research method uses rabbits 4 tails made 5 wounds on the back, consisting of negative control, comparison (Bioplacenton®), gel preparations 3%, 5%, and 11%. Wound diameter measurements were carried out on days 3, 6, 9, 12, 15 and 18. The parameters observed were the size of the wound diameter, wound healing such as wound drying, scab formation, closure of the wound and the growth of new hair around the wound. An inflammatory process occurs for 3 days after injury and not processed wound healing. Fibroblasts appeared on day 6 and peaked on day 9, so that on day 9 all treatment and control groups experienced linear healing. On the 9th day the fibroblasts began to peel off on the skin indicating the group has reached the peak of the proliferation phase and wound contractions occur gradually urgent. The results of the guava leaf extract gel activity test (Psidium guajava L) showed a concentration of 11% gave the best effect.

PENGARUH PEMBIASAAN SHALAT DHUHA TERHADAP KECERDASAN SPIRITUAL PESERTA DIDIK Susilawati, Elis; Sulaeman, Oyib; KURNIAWAN, Ase
THORIQOTUNA: Jurnal Pendidikan Islam Vol. 5 No. 2 (2022): THORIQOTUNA: Jurnal Pendidikan Islam
Publisher : Prodi PAI IAILM Suryalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47971/tjpi.v5i2.565

The study aims to determine the influence of habituation dhuha prayer on the spiritual intelligence of students at MA Muslimin Panjalu. The method used is a quantitative descriptive, data prcessing through Spearman rank correlation ( ). The result showed that the influence of habituation dhuha prayer on the spiritual intelligence of students at MA Muslimin Panjalu was quite significant, = 0.65 was in the interval 0.61 – 0.80 with high classification. And (3.80) ≥ (1.729). The habituation dhuha prayer can increase spiritual intelligence of students by 42.25%, so that 57.75% of spiritual intelligence of students is influenced by other factors outside of the research Penelitian ini bertujuan untuk mengetahui pengaruh pembiasaan shalat dhuha terhadap kecerdasan spiritual peserta didik di MA Muslimin Panjalu. Metode yang digunakan adalah kuantitatif deskriptif, pengolahan data melalui rank spearman (). Hasil penelitian diperoleh pengaruh pembiasaan shalat dhuha terhadap kecerdasan spiritual peserta didik di MA Muslimin Panjalu cukup signifikan dengan kategori tinggi berdasarkan = 0.65 berada pada interval 0.61 – 0.80 dengan klasifikasi tinggi. Serta (3.80) ≥ (1.729). Pembiasaan shalat dhuha mempengaruhi kecerdasan spiritual peserta didik sebesar 42.25%, sedangkan 57.75% kecerdasan spiritual peserta didik dipengaruhi oleh faktor lain diluar penelitian

Implementasi shalat dhuha dalam meningkatkan kecerdasan spiritual peserta didik Susilawati, Elis; Sulaeman, Oyib; Kurniawan, Ase
THORIQOTUNA: Jurnal Pendidikan Islam Vol. 6 No. 1 (2023): THORIQOTUNA: Jurnal Pendidikan Islam
Publisher : Prodi PAI IAILM Suryalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47971/tjpi.v6i1.687

Penelitian ini bertujuan untuk mengetahui pengaruh pembiasaan shalat dhuha terhadap kecerdasan spiritual peserta didik di MA Muslimin Panjalu. Metode yang digunakan adalah kuantitatif deskriptif, pengolahan data melalui rank spearman (r_s). Hasil penelitian diperoleh pengaruh pembiasaan shalat dhuha terhadap kecerdasan spiritual peserta didik di MA Muslimin Panjalu cukup signifikan dengan kategori tinggi berdasarkan r_s = 0.65 berada pada interval 0.61 – 0.80 dengan klasifikasi tinggi. Serta t_(hitung ) (3.80) ≥ t_tabel (1.729). Pembiasaan shalat dhuha mempengaruhi kecerdasan spiritual peserta didik sebesar 42.25%, sedangkan 57.75% kecerdasan spiritual peserta didik dipengaruhi oleh faktor lain diluar penelitian

KENALI DAN SADARI DIABETES SEJAK DINI: PROGRAM EDUKASI DAN SKRINING KESEHATAN MASYARAKAT DESA MANDALAWANGI, KECAMATAN NAGREG, KABUPATEN BANDUNG Sri Mas Hartini, Ni Nyoman; Susilawati, Elis; Supriadi, Dadih; Sutoro, Meylani; Lisni, Ida; Priyadi, Akhmad
Batara Wisnu : Indonesian Journal of Community Services Vol. 5 No. 3 (2025): Batara Wisnu | September - Desember 2025
Publisher : Gapenas Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53363/bw.v5i3.435

Diabetes mellitus is one of the growing public health problems, particularly in rural areas such as Mandalawangi Village, Nagreg Subdistrict, Bandung Regency. Low public awareness of early detection and healthy lifestyle practices has contributed to the increasing prevalence of diabetes. This community service program was carried out using a participatory approach, which included interactive health education, random blood glucose screening, and lifestyle counseling. A total of 78 participants were involved and underwent pre-test and post-test assessments. The results showed that education significantly improved participants’ knowledge, as indicated by a statistically significant difference between pre-test and post-test scores (8.33 vs 8.94; p=0.0058). Screening results revealed that 15.4% of participants were categorized as pre-diabetic and 6.4% as diabetic. The establishment of the *Mandalawangi Healthy Community* serves as a follow-up initiative to ensure the sustainability of the program. Overall, the education and screening activities successfully enhanced community knowledge and awareness about diabetes and provided an important foundation for managing healthy lifestyles and preventing further complications.

Co-Authors Agus Sulaeman Agus Sulaeman Agustian, Salim Ahmad Bahtiar, Ahmad Aligita, Widhya Amanda, Ruli Anggraeni, Vina Juliana Anggreini, Tyas Septiana Aolina, Shelin Aritonang, Meiadi Putra Utama Astuti, Ayu Dwi Ating Cicih Auliyaa, Millata Bagus Fauzan Nuur Budiana, Wempi Dadih Supriadi, Dadih Denni Fransiska Helena Desianti, Gina Deti Siti Fatimah Dulce De Sousa Tpoy ED. Yunisa Mega Pasha Etty Gurendrawati, Etty Fatmawati, Fenti Feliana, Marita Fionna, Elvania Fisheri, Neng Garnadi Jafar, Garnadi Hartini, Ni Nyoman Sri Mas Herdiana, Geralda Bintang Herlina Husein I Gusti Agung Ayu Hari Triandini I Ketut Adnyana Ida Lisni Idar, Idar Irviansyah, Cepy Okta Istiqomah, Aulia Nurfazri Juanda, Dadang Jutti Levita Khairunnisa, Hera Kurniawan, Ase Maia de Fatima Freitas, Floriana Marita Kaniawati Meylani Sutoro Neneng Elviana Noviyanti, Eva Nurfazri, Aulia P.S, Christina Betharia Pasha, ED Yunisa Mega PERTIWI, INTAN Pratama, Reza Priyadi, Akhmad Putri Aji, Rizka Ananda Rahayu, Ismah Rahman, Toni Abdul Rahmanda, Erin Reza Pratama Salsabila, Akifah Humaira Salsabilla, Syifa Selifiana, Nita Setiawan, Finna Shintya Safitri Silviana, Neneng Sinaga, Yakobus Lau De Yung Soni Muhsinin Sri Adi Sumiwi Sri Lestari Kartikawati Sri Mas Hartini, Ni Nyoman Sukmawati, ika kurnia Sulaeman, Oyib Supriyatini Kartadarma Susilawati, Yasminwar Sutrisno, Entris Suwendar Suwendar Sya’bani, Oktaviani Syihabbudin, Nazar Widhya Aligita Wijaya, Youland Friccilia Yakobus Sinaga Yani Mulyani Yanyan Mulyani Yasmiwar Susilawati Yulianie, Rany Yuniarto, Ari Zinan, Daula Zahra Ziska, Rahma

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