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All Journal Jurnal Gizi dan Pangan E-Jurnal Medika Udayana Jurnal Kedokteran Syiah Kuala AL KAUNIYAH Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Jurnal Manajemen Kesehatan Indonesia Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Wikrama Parahita : Jurnal Pengabdian Masyarakat JURNAL PENDIDIKAN JASMANI DAN OLAHRAGA Buletin Farmatera Jurnal Pengabdian Masyarakat AbdiMas Majalah Kedokteran Andalas Jurnal Biomedika dan Kesehatan Jurnal Muara Sains, Teknologi, Kedokteran dan Ilmu Kesehatan SULUH: Jurnal Abdimas Abdimas UNWAHAS : Jurnal Pengabdian Masyarakat UNWAHAS World Nutrition Journal SEGARA : Jurnal Pengabdian Kepada Masyarakat
Maria Selvester Thadeus
Universitas Pembangunan Nasional Veteran Jakarta
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Relation between nutrition intake, prediabetes, and central obesity with handgrip strength in Indonesian medical student Annisa Afifah; Mila Citrawati; Thadeus, Maria Selvester; Nugrahayu Widyawardani
World Nutrition Journal Vol. 8 No. i1 (2024): Volume 08 Issue 1, August 2024
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V08.i1.0011

Abstract

Background: Muscles are crucial in creating movement, stabilising body posture, and regulating body temperature. Muscle strength can be assessed using handgrip strength. Handgrip strength can predict muscle function, nutritional status, diabetes risk, and the risk of metabolic syndrome. Handgrip strength can be influenced by muscle mass, nutritional intake, fat mass, physical activity level, and metabolic syndrome. Objective: This research is to find relationship between handgrip strength and nutritional intake, muscle mass, and central obesity. Methods: The research was conducted as a cross-sectional study using observational analytical methods. The sample consisted of 53 individuals selected through purposive sampling. Handgrip strength can be measured using a hand dynamometer, nutritional intake using a 2x24 hour food recall, muscle mass using a body composition analyzer, central obesity using waist to hip ratio, and fasting blood sugar using a glucometer. Statistical data analysis employed the chi-square test and independent T-test. Results: The results indicated a relationship between central obesity and handgrip strength (p = 0.006). Researchers are interested in studying muscle strength and its predictors concerning central obesity, prediabetes, and nutritional status in medical students. The results indicated a relationship between handgrip strength and central obesity (p = 0.006), but no relationship was found between handgrip strength and energy intake (p = 0.235), protein intake (p = 0.524), and prediabetes (p = 0.272). Conclusion: There is a relationship between central obesity and handgrip strength. Future researchers are encouraged to consider additional factors, including physical activity, muscle mass index, and comorbidities.
The Effect of Moringa Leaf Extract Administration on Sperm Morphology and Blood Glucose Reduction in Alloxan-Induced Sprague Dawley Rats Dinda Nuraini Hanifah Wahab; Uswatun Hasanah; Erna Harfiani; Maria Selvester Thadeus
Al-Kauniyah: Jurnal Biologi Vol 18, No 1 (2025): AL-KAUNIYAH JURNAL BIOLOGI
Publisher : Department of Biology, Faculty of Science and Technology, Syarif Hidayatullah State Islami

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/kauniyah.v1i1.37286

Abstract

AbstractIncreased blood sugar levels can be triggered by increased intake or insulin resistance, leading to increased oxidative stress that affects sperm quality during spermatogenesis. Moringa oleifera, rich in antioxidants, has been proven effective in improving sperm quality through several studies. This study aims to evaluate the influence of moringa leaf extract on sperm morphology and the reduction of blood sugar levels in Sprague Dawley white rats (Rattus norvegicus) induced by alloxan. Fasting blood sugar tests showed that rats induced with alloxan without moringa leaf extract had the highest blood sugar levels among the groups. In contrast, the negative control and treatment groups with moringa leaf extract successfully maintained blood sugar levels at normal levels. Normal sperm morphology reached 94.5% in the treatment group with the highest dose of moringa leaf extract. The results of the study indicate a significant relationship between blood sugar levels and sperm morphology in alloxan-induced white rats after the administration of moringa leaf extract. Moringa oleifera has the potential to be a therapeutic intervention to improve sperm quality and control blood sugar levels in hyperglycemic conditions.AbstrakPeningkatan kadar gula darah dapat dipicu oleh peningkatan asupan atau resistensi insulin menyebabkan peningkatan stres oksidatif yang mempengaruhi kualitas sperma selama spermatogenesis. Tanaman kelor (Moringa oleifera), tumbuhan yang kaya akan antioksidan, telah terbukti efektif dalam meningkatkan kualitas sperma melalui beberapa penelitian. Penelitian ini bertujuan untuk mengevaluasi pengaruh ekstrak daun kelor terhadap morfologi sperma dan pengurangan kadar gula darah pada tikus putih Sprague Dawley (Rattus norvegicus) yang diinduksi aloksan. Uji gula darah puasa menunjukkan bahwa tikus yang diinduksi aloksan tanpa perlakuan ekstrak daun kelor memiliki kadar gula darah tertinggi di antara kelompok-kelompok lainnya. Sebaliknya, kelompok kontrol negatif dan kelompok perlakuan dengan ekstrak daun kelor berhasil menjaga kadar gula darah pada tingkat normal. Morfologi sperma normal mencapai 94,5% pada kelompok perlakuan dengan dosis 400 mg/kgBB ekstrak daun kelor. Kesimpulan yang didapatkan pada penelitian ini berkaitan dengan temuan hubungan signifikan antara kadar gula darah dan morfologi sperma pada tikus putih yang diinduksi aloksan setelah pemberian ekstrak daun kelor. Tanaman kelor (Moringa oleifera) memiliki potensi sebagai intervensi terapeutik untuk meningkatkan kualitas sperma dan mengendalikan kadar gula darah dalam kondisi hiperglikemia. 
Pelatihan Cuci Tangan Pakai Sabun (CTPS) untuk pencegahan dan pengendalian infeksi diare dan thyphoid anak di desa pangkalan jati cinere depok Selvester Thadeus, Maria; Susantiningsih, Tiwuk; Simanjuntak, Kristina; Yuliyanti, Retno; Citrawati, Mila
Segara : Jurnal Pengabdian Kepada Masyarakat Vol 2 No 1 (2024): Vol. 2 No. 1 (2024): SEGARA : Jurnal Pengabdian Kepada Masyarakat (In Press)
Publisher : Fakultas Kedokteran UPN "Veteran" Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/segara.v2i1.6095

Abstract

Cuci Tangan Pakai Sabun (CTPS) adalah salah satu bentuk Perilaku Hidup Bersih dan Sehat (PHBS) untuk mencegah dan mengendalikan infeksi diare dan thyphoid terutama pada anak anak. Insiden infeksi diare dan thyphoid pada anak masih tinggi. Kebersihan tangan menjadi salah satu faktor pencegahan penularan infeksi diare dan thyphoid melalui makanan yang dipegang dengan tangan yang kotor. Tim Pengabdian Kepada Masyarakat Fakultas Kedokteran UPN Veteran Jakarta telah melakukan pelatihan Cuci Tangan Pakai Sabun (CTPS) sebagai sarana edukasi dan pelatihan pencegahan dan pengendalian infeksi diare dan thyphoid pada anak di Desa Pangkalan Jati Cinere Depok. Responden yang mengikuti kegiatan ini sebanyak 40 anak usia 8-12 tahun. Pelatihan menggunakan media powerpoint dan brosur CTPS serta praktek langsung CTPS. Hasil penilaian nilai pretest sebesar 70,25% dan setelah dilakukan penyuluhan dan pelatihan, kemudian dilakukan posttest terjadi peningkatan nilai posttest sebesar 22% menjadi 92,25%. Disela sela pelatihan responden diminta untuk melakukan CTPS agar ketrampilan CTPS semakin baik. CTPS adalah salah satu ketrampilan yang dapat diterapkan pada anak anak untuk pencegahan dan pengendalian infeksi diare dan thyphoid pada anak.
a Penyuluhan Kesehatan Pada Kasus Demam Berdarah Dengue Di UPTD Pengasinan Depok dengan Pendekatan Dokter Keluarga : Penyuluhan Kesehatan Pada Kasus Demam Berdarah Dengue Di UPTD Pengasinan Depok dengan Pendekatan Dokter Keluarga Citrawati, Mila; Susantiningsih, Tiwuk; Thadeus, Maria Selvester; Adisaputra, Chantika Zahra; Nooramadhani, Tasya; Cahyaninglatri, Wendi Corlia
Segara : Jurnal Pengabdian Kepada Masyarakat Vol 2 No 2 (2024): Vol. 2 No. 2 (2024): SEGARA : Jurnal Pengabdian Kepada Masyarakat
Publisher : Fakultas Kedokteran UPN "Veteran" Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/segara.v2i2.9922

Abstract

Penyuluhan kesehatan dengan pendekatan dokter keluarga pada kasus demam berdarah dengue (DBD) adalah solusi bagi penatalaksanaan kasus kedokteran yang berfokus pada pemberian layanan kesehatan primer yang komprehensif, berkesinambungan, dan berpusat pada individu, keluarga, serta komunitas. Terdapat peningkatan kasus DBD dari tahun 2023 ke 2024 sehingga peran kedokteran keluarga penting untuk menyelesaikan masalah ini, dimulai dari screening hingga edukasi kepada keluarga untuk mengurangi presentase angka kejadian terutama di wilayah UPDT Pengasinan, Depok. Penyuluhan kesehatan diperlukan untuk mengidentifikasi daftar masalah klinis pada pasien dan keluarga serta factor-faktor yang mempengaruhi masalah demam berdarah dengue, mengubah pengetahuan dan perilaku dalam pencegahan demam berdarah dengue yang berikatan terhadap kesehatan pasien serta keluarga. Keterlibatan partisipasi keluarga dalam mengatasi masalah kesehatan pasien dengan pendekatan kedokteran keluarga sangat diperlukan. Kegiatan pengabdian kepada masyarakat ini dilakukan di UPTD Pengasinan Depok dengan pendekatan kedokteran keluarga. Kegiatan penyuluhan kesehatan pada kasus demam berdarah dengue di UPTD Pengasinan Depok dengan pendekatan dokter keluarga di dapatkan bahwa dari hasil evaluasi dan penatalaksanaan terdapat perbaikan terhadap pengetahuan dan sikap yang menjadi baik, salah satunya yaitu perilaku untuk melakukan 3M dan mencoba membuka diri untuk berkegiatan sosial di lingkungan rumah. Pengetahuan dan perilaku tersebut sangat mempengaruhi pasien dan keluarga karena merasakan kualitas hidupnya yang membaik dan nyaman saat berada di lingkungan rumah.
Perbedaan efek ekstrak buah naga merah (Hylocereus polyrhizus) dan ekstrak buah naga putih (Hylocereus undatus) terhadap kadar kolesterol total tikus putih (Rattus norvegicus) Prakoso, Luthfi Octafyan; Yusmaini, Hany; Thadeus, Maria Selvester; Wiyono, Sugeng
Jurnal Gizi dan Pangan Vol. 12 No. 3 (2017)
Publisher : The Food and Nutrition Society of Indonesia in collaboration with the Department of Community Nutrition, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (323.377 KB) | DOI: 10.25182/jgp.2017.12.3.195-202

Abstract

This study aimed to compare the effect of red dragon fruit extract (Hylocereus polyrhizus) and white dragon fruit extract (Hylocereus undatus) to total cholesterol levels in white rats (Rattus norvegicus). Total of 30 males white wistar strains were divided into five treatments i.e: (1) standard feed and Na-CMC 1% (K1), (2) standard feed and quail egg 10ml/kgBW (K2), (3) standard feed, quail egg 10ml/kgBW and simvastatin dose 0,72mg/day (P1), (4) standard feed, quail egg 10ml/kgBW and red dragon fruit extract dose 60mg/200gBW/day (P2), (3) standard feed, quail egg 10 ml/kgBW and white dragon fruit extract dose 120mg/200gBW/day (P3). The intervention was carried out for 14 days after 7 days acclimatization period. Data was analyzed by One Way ANOVA test and continued with Post Hoc Bonferroni test (p=0.05). In P2 group, there was a difference of total blood cholesterol level by 25.83 mg/dl compared with the positive control group and statistically significant (p<0.05). In P1 and P3 group there were difference in cholesterol levels of 9.5 mg/dl and 11.5 mg/dl compared with the positive control group, but not statistically significant (p>0.05). The comparison between red dragon extract group and white dragon extract showed a non-significant difference (p>0.05). Red dragon fruit extract and white dragon extract have a potential effect to improve hypercholesterolemia conditions.
The Therapeutic Effects of West Indian Elm (Guazuma ulmifolia) Leaf Extract on Coronary Artery Atherosclerosis in Hypercholesterolemic Wistar Rats Ramadhansyah, Reza; Thadeus, Maria Selvester; Muktamiroh, Hikmah; Hardini, Niniek
Jurnal Gizi dan Pangan Vol. 18 No. 2 (2023)
Publisher : The Food and Nutrition Society of Indonesia in collaboration with the Department of Community Nutrition, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25182/jgp.2023.18.2.109-116

Abstract

This study aimed to determine the therapeutic effect of West Indian elm leaf extract on coronary artery atherosclerosis in hypercholesterolemia Wistar rats. Cholesterol, a key factor in the pathophysiology of coronary heart disease, is present in fat-containing diets. Orlistat is one of the medications that can reduce blood cholesterol levels, but since it has side effects, herbs are more preferable to it. One such herbal plant, West Indian elm (Guazuma ulmifolia), contains tannins, saponins, alkaloids, and flavonoids, secondary metabolites that carry the properties necessary to reduce blood cholesterol levels, in its leaves. In this experimental study, which focused on histopathological parameters to see the scale of progression of coronary artery atherosclerosis, 30 Wistar rats were induced with a high-fat diet and divided into 6 sample groups, consisting of three control groups (normal, negative, and positive) and three treatment groups (which received a West Indian elm leaf extract at 0.2, 0.4, and 0.8 g/kgBW). Significant results were obtained from both Kruskal-Wallis and Mann-Whitney tests (p<0.05) between the negative control group and the positive control group, between the negative control group and treatment group 2 (0.4 g/kgBW), and between the negative control group and treatment group 3 (0.8 g/kgBW). In conclusion, this study proved that West Indian elm (Guazuma ulmifolia) leaf extract reduces the development of coronary atherosclerosis and shares a similarity in therapeutic effect with orlistat.
Pengaruh Cotrimoxazole Terhadap Perkembangan Neural Tube Embrio Ayam Alifia Shafanaura Pamuji; Cut Fauziah; Yanto Sandy Tjang; Maria Selvester Thadeus
Jurnal Biomedika dan Kesehatan Vol 7 No 2 (2024)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2024.v7.190-198

Abstract

Background In Indonesia, congenital abnormalities are still very high. Neural Tube Defect (NTD) is one of the most common congenital abnormalities. NTD occurs due to the failure of neural plate closing. One of the risk factors for NTD is folic acid deficiency. Drug use during pregnancy is one of the risk factors for congenital abnormalities. Cotrimoxazole is an anti-folate drug that still has pros and cons regarding its potential to cause NTD. Human embryonic brain development can be simulated using chicken embryos. This study aimed to determine the effect of Cotrimoxazole on the development of the chicken embryo's neural tube. Methods This study used a post-test-only control group design. The number of samples is 30 eggs and the sampling method was simple random sampling. The dose of Cotrimoxazole used was 0; 60; and 120 mg/kg per egg then the eggs were incubated for 72 hours. Data analysis was based on sample characteristics and bivariate analysis using the comparative Kruskal-Wallis test with the post-hoc test. Results In this study, 11 out of 30 eggs could be analyzed. The results were obtained by observing the number of brain vesicles. There was a significant difference in the number of brain vesicles (p= 0.046) between the study groups from the Kruskal-Wallis test. Conclusions Cotrimoxazole administration showed an effect on neural tube development of chicken embryos when compared to controls.
Usia dan Indeks Massa Tubuh dalam Kaitannya dengan Grading Karsinoma Mammae Invasif NST Jannati, Husna Bunga; Hardini, Niniek; Nugrohowati, Nunuk; Thadeus, Maria Selvester; Rahadiati, Familia Bella
Majalah Kedokteran Andalas Vol. 46 No. 3 (2023): Supplementary July 2023
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i5.p836-846.2023

Abstract

Tujuan: Tujuan dari penulisan artikel ini adalah untuk mencari adanya keterkaitan antara indeks massa tubuh dan usia terhadap grading histopatologi karsinoma mammae invasif NST di RSPAD Gatot Soebroto tahun 2021. Metode: Penelitian kuantitatif analitik observasional menggunakan cross sectional sebagai desain penelitian. Pasien karsinoma mammae invasif NST yang tercatat pada tahun 2021 dirawat di RSPAD Gatot Soebroto adalah populasi, sampel adalah pasien yang telah disesuaikan dengan kriteria inklusi. Teknik simple random sampling dipilih menjadi teknik pengambilan sampel yang berasal dari data sekunder berupa rekam medis pasien, sampel digunakan sampel sebanyak 84 pasien. Indeks massa tubuh dan usia adalah variabel bebas dan grading adalah variabel terikat. Analisis univariat dilakukan untuk mengetahui karakteristik pasien berdasarkan usia, IMT, dan grading. Analisis bivariat bertujuan untuk mencari adanya keterkaitan antara variabel independen dan variabel dependen. Hasil: Tidak adanya hubungan yang bermakna ditemukan pada penelitian ini antara variabel IMT dengan grading dengan nilai p=0,685 sementara pada analisis mengenai keterkaitan usia dengan grading juga ditemukan tidak adanya hubungan dengan p=1. Kesimpulan: hubungan antara IMT dan usia dengan grading tidak ditemukan, kemungkinan tidak adanya hubungan akibat terbatasnya sampel. Subtipe molekuler dan status menopause sebagai faktor pembias.
Co-Authors Abdullah Rukman Adisaputra, Chantika Zahra Adrian Dharmawan Adyatma, Hilmi Agneta Irmarahayu Akbar, Rafi Thoriq Alifia Shafanaura Pamuji Annisa Afifah Cahyaninglatri, Wendi Corlia Cut Fauziah Cut Fauziah Cut Fauziah Cut Fauziah Dimas Farhan Wibawanto Dinda Nuraini Hanifah Wahab Dorlina Nainggolan Eko Satrio Bahari Erna Harfiani Fachruddin Perdana Fadhilah Sharfina Alyani Fajriati Zulfa Fajriati Zulfa Familia Bella Rahadiati Giopratiwi, Kusvandita Hany Yusmaini Hardini, Niniek Hikmah Muktamiroh Husna Bunga Jannati Ibnu Wadud Pujangga Inasa Nabila Jannati, Husna Bunga Kristina Simanjuntak Kristina Simanjuntak Kristina Simanjuntak Meiskha Bahar Mila Citrawati Muktamiroh Hikmah Nadira Safa Jasmine Nazira, Syarifah Niniek Hardini Niniek Hardini Noor Az Zhahra Nooramadhani, Tasya Nugrahayu Widyawardani Nunuk Nugrohowati Nurfitri Bustamam Perdana Fachruddin Prakoso, Luthfi Octafyan Rahadiati, Familia Bella Ramadhansyah, Reza Retno Yulianti Retno Yuliyanti Rukman Abdullah Ryan Herardi Salman Paris Salman Paris Setyaningsih, Yuni Simanjuntak, Kristina Sri Wahyuningsih Sugeng Wiyono Sukrisno, Adi Tiwuk Susantiningsih Tri Faranita, Tri Uswatun Hasanah Wibawanto, Dimas Farhan Yanto Sandy Tjang Yudhi Nugraha Yuliyanti, Retno