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The effects of regular exercise on hippocampal estradiol levels and spatial memory of ovariectomized Sprague Dawley rats Sri Kadarsih Soejono, Siti Kaidah Ginus Partadiredja
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 45, No 02 (2013)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (71.551 KB)

Abstract

The decrease of estrogen levels leads to dysfunction of hippocampus, including spatial learning and memory. Previous studies have shown that physical exercise improved spatial memory of ovariectomized rats. Physical exercise was observed to be associated with increased extragonadal aromatization and neurotrophin synthesis. This study aimed to evaluate the effect of regular exercise on serum and hippocampal estrogens levels and the spatial memory of ovariectomized rats. The present study used 10 ovariectomized Sprague Dawley rats aged 12 weeks. The rats were randomly assigned into two groups with five rats in each group. Group I was exercise group and Group II was control group without exercise. During the exercise period, the rats were required to keep running constantly on the treadmill at a speed of 18 m/min and at the slope of 5% for a total duration of 60 minutes per day. The exercise was performed five times per week for 12 weeks. The spatial memory of rats was measured using Morris water maze. After the exercise program was completed, the blood and hippocampus samples were collected to determine the estrogen levels. This study revealed that the mean levels of hippocampal estrogen of exercise group (33.794 ± 4.760 pg/mL/100mg tissue weight) were significantly higher than that ofcontrol group (20.552 ± 2.057 pg/mL/100 mg tissue weight) (p<0.05). However, there was no significant difference in serum estrogen levels between the exercise group (26.070 ± 4.064 pg/mL/100mg tissue weight) and control group (24.530 ± 8.661 pg/mL/100mg tissue weight) (p>0.05). In the Morris water maze tests, there was no difference in the spatial learning between both groups (p>0.05). The spatial memory retention of the exercise group was significantly better than control group (p<0.05). In conclusion, regular exercise increases hippocampal estrogen levels and improves spatial memory of ovariectomized rats. Keywords: exercise - hippocampus - spatial memory - estrogen - ERβ
Moderate-intensity interval exercise but not high-intensity interval exercise improves the spatial memory of ovariectomized rats Kaidah, Siti; Rauf, Saidah; Soesatyo, Marsetyawan HNE; Agustiningsih, Denny; Partadiredja, Ginus
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 50, No 3 (2018)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (518.401 KB) | DOI: 10.19106/JMedScie/005003201804

Abstract

Physical exercise exerts beneficial effects on the spatial learning and memory. High-intensity interval exercise (HIIE) has been proposed as a time-efficient physical exercise regimen. On the other hand, there were evidences that HIIE increased oxidative stress biomarkers and reduced antioxidant capacity, which resulted in oxidative damage. The present study aimed to investigate the effects of high-intensity interval exercise and moderate-intensity interval exercise on oxidative stress biomarkers and oxidative enzymes activity in the hippocampus and the spatial memory of ovariectomized rats. A total of 16 female Sprague Dawley rats aged 12 weeks were randomly assigned into 4 groups, i.e. the sham-operated (SO), ovariectomized without exercise (O), ovariectomized with high-intensity interval exercise (HIIE), and ovariectomized with moderate-intensity interval exercise (MIIE) groups. Rats of the exercise groups (HIIE & MIIE groups) performed 6 sessions of interval exercise per week for 6 weeks. The spatial memory of rats was measured using the Morris water maze procedure. The malondialdehyde (MDA) levels and activity of catalase (Cat) as well as glutathione peroxidase (GPx) in hippocampus were determined using spectrophotometry method. The spatial learning and memory retention of the moderate-intensity interval exercise group was significantly better than that of the high-intensity interval exercise group. The GPx activity of MIIE group was higher than any other groups. The SO group had the lowest hippocampal MDA level and highest Cat activity among groups. Moderate-intensity interval exercise reduces the ovariectomy induced-oxidative stress in the hippocampus and improves spatial learning and memory retention of ovariectomized rats.
Correlation of Stone Size and Urine Leukocytes in Nephrolithiasis Patients at Ulin General Hospital Banjarmasin Noorsyifa Safitri Tahir; Eka Yudha Rahman; Dewi Indah Noviana Pratiwi; Heru Prasetya; Siti Kaidah
Berkala Kedokteran Vol 17, No 1 (2021)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (226.757 KB) | DOI: 10.20527/jbk.v17i1.10246

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Abstract: Nephrolithiasis (Kidney Stone) is a condition where there is stone in the kidney that are formed due to disturbance of the balance between solubility and deposition of salt in urine. This study was aim to determine the correlation between stone size and urine leukocytes in nephrolithiasis patients. This study was conducted at the Ulin General Hospital in Banjarmasin by taking data on medical records for the 2017-2018 period. This study used a cross-sectional retrospective approach with an analytic method. Samples were obtained using total sampling technique based on inclusion and exclusion criteria. A total of 34 nephrolithiasis patients were obtained that met the inclusion and exclusion criteria. The highest proportion of stone size was >20 mm (47.07%). The highest proportion of urine leukocytes was +3 (38.23%). Data were analyzed using the Spearman correlation test and showed p = 0.774 and r = 0.051. There was no significant correlation between stone size and urine leukocytes in nephrolithiasis patients at Ulin General Hospital Banjarmasin. Keywords: Nephrolithiasis, kidney stone size, urine leukocytes.
Correlations of Prostate Volume with PSA Levels in BPH Patients at Ulin General Hospital Banjarmasin Nur Ramadhanti Cindy Levissa; Eka Yudha Rahman; Dewi Indah Noviana Pratiwi; Heru Prasetya; Siti Kaidah
Berkala Kedokteran Vol 17, No 1 (2021)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (270.029 KB) | DOI: 10.20527/jbk.v17i1.10245

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Abstract: This study aims to determine the association between prostate volume and PSA levels in BPH patients at Ulin Hospital Banjarmasin. This study used a cross-sectional retrospective approach and analytic method. A total of 52 samples were obtained by purposive sampling based on inclusion and exclusion criterias. The highest prostate volume of  20.00-39.99 cc was obtained from 16 patients (30.7%) and the lowest volume of  60.00-79.99 cc was obtained from 10 patients (19.2%). Examination of PSA levels were highest at 2.6-9.9 ng/mL from 24 patients (46.2%) and the lowest at >20.0 ng/mL (5.8%) from 3 patients. Data analysis using Pearson correlation coefficient showed a positive correlation between prostate volume and PSA levels in BPH patients at Ulin Hospital Banjarmasin with a p value = 0,000 and r = 0.616 (positive and strong correlation). Keywords: BPH, Prostate volume, PSA
Characteristics of Nephrolithiasis Patients at Ulin General Hospital Banjarmasin 2017-2018 Period Nazmyatus Sa’idah; Eka Yudha Rahman; Dewi Indah Noviana Pratiwi; Heru Prasetya; Siti Kaidah
Berkala Kedokteran Vol 17, No 1 (2021)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (333.546 KB) | DOI: 10.20527/jbk.v17i1.10247

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Abstract: The purpose of this study was to determine the characteristics of nephrolithiasis patients at Ulin General Hospital Banjarmasin based on sex, age, and residence place of patients. This study was conducted at Ulin General Hospital Banjarmasin, using a descriptive method with a retrospective approach. A total of 100 nephrolithiasis patients were obtained by total sampling according to inclusion and exclusion criteria.  The results of this study showed that all nephrolithiasis patients in the 2017-2018 period were recorded, there were 58 male patients (58%), while there were 42 female patients (42%). The results showed that nephrolithiasis patients at Ulin General Hospital Banjarmasin were more than 55-64 years old (31%) and Banjarmasin was the area where most nephrolithiasis patients with a number of 35 patients (35%). This study showed the characteristics of age, sex, and residence place of patients were the risk factors that influence the incidence of nephrolithiasis at Ulin General Hospital Banjarmasin. Keywords: Patient Characteristics, Nephrolithiasis, Ulin General Hospital Banjarmasin.
EDUKASI PEMBUATAN SEDIAAN ANTISEPTIK TANAMAN HERBAL DI KELURAHAN PEMURUS BARU BANJARMASIN [EDUCATION ON MAKING ANTISEPTIC PREPARATIONS FOR HERBAL PLANTS IN BANJARMASIN KELURAHAN PEMURUS BARU] Lia Yulia Budiarti; Siti Kaidah; Alfi Yasmina
Jurnal Sinergitas PKM & CSR Vol 5, No 1 (2021): April
Publisher : Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/jspc.v5i1.3436

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South Kalimantan is ranked sixth as the province with the highest percentage of Covid-19 positive cases in Indonesia. As of July 24, 2020, there were 4,990 (5.7%) confirmed positive cases of Covid-19 in South Kalimantan which is the highest cases occurred in Banjarmasin Regency. Pemurus Baru, an urban village of Banjarmasin Regency is one of the red zone area of Covid-19 positive cases.  One of the health protocols to prevent covid-19 exposure is washing hands frequently with antiseptic. Antiseptic liquid can be made from herbal plant ingredients that have antimicrobial efficacy.  The development of online technology can be a tool of education and delivery of information that benefits the community. The purpose of this program is to support the Covid-19 prevention efforts through the useful of herbal plants into antiseptic liquid, in order to avoid Covid-19 exposure. The targets of this program are the mothers of health cadres in the working area of Pemurus Baru Community Health Center of Banjarmasin Regency. Education method in this program is counseling on the manufacture of antiseptics from the herbal plant. Education and evaluation of the program are carried out online. The results of this program have a positive impact, the targets of program understand and are able to make antiseptic liquid based on herbs, and motivated to inform to others or communities. BAHASA INDONESIA ABSTRACT: Kalimantan Selatan berada diurutan ke-enam sebagai provinsi dengan persentase tertinggi kasus positif Covid-19 di Indonesia. Pada 24 Juli 2020 didapatkan sebanyak 4.990 (5,7%) kasus terkonfirmasi positif Covid-19 di Kalimantan Selatan dan   kasus teringgi terjadi di Kota Banjarmasin. Kelurahan Pemurus Baru Kota Banjarmasin termasuk salah satu kelurahan yang termasuk wilayah zona merah kasus positif Covid-19.  Salah satu protokol kesehatan untuk memcegah paparan covid-19 adalah mencuci tangan dengan antiseptik. Sediaan antiseptik tangan dapat dibuat dari bahan tanaman herbal yang berkhasiat antimikroba.  Berkembangnya teknologi online dapat menjadi suatu sarana edukasi dan penyampaian informasi yang bermafaat bagi masyarakat. Tujuan kegiatan ini adalah untuk mendukung upaya pencegahan COVID-19 melalui pemanfaatan tanaman herbal menjadi sediaan antiseptik, guna terhindar dari paparan Covid-19. Sasaran kegiatan adalah ibu-ibu kader kesehatan di wilayah kerja Puskesmas Pemurus Baru Banjarmasin. Metode pelaksanaan edukasi berupa penyuluhan tentang pembuatan antiseptik dari sediaan tanaman herbal. Edukasi dan evaluasi kegiatan dilakukan secara online. Hasil dari kegiatan ini dapat berdampak positif, sasaran kegiatan memahami  dan mampu membuat sediaan antiseptik berbahan dasar  tanaman herbal,  serta termotivasi untuk menginformasikannya pada orang lain/masyarakat lainnya.
Effect of Ethanol Extract Karamunting Leaf (Rhodomyrtus Tomentosa (Aiton) Hassk) on Testosterone Hormone Levels of Diabetes Mellitus Model Rats Husnul Khatimah; Lena Rosida; Siti Kaidah; Ida Yuliana
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 15, No 2 (2021): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v15i2.3452

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Karamunting leaf is a natural ingredient in South Kalimantan and is used for the treatment of diabetes mellitus. Diabetes mellitus (DM) can decrease hormone testosterone. Research on Karamunting leaves on testosterone levels had not been widely studied. The aim was to analyse the effect of administration ethanol extract Karamunting leaf on testosterone levels in diabetic rats induced by streptozotocin. The method was true experimental,  Posttest Control Group. The research groups were divided into 4 groups. The control group giving streptozotocin induction at dosage 40 mg/kg bw rats intra-peritoneally. The treatment group was a group of rats DM  treated with ethanol extract of Karamunting leaf at dosage 100 mg/kg bw, 200 mg/kg bw, and 400 mg/kg bw. The treatment in the research group was carried out for 14 days. On day 15, blood was taken to measure testosterone levels by the ELISA method and glucose blood. The data were analysed with Kolmogorov Smirnov and Mann Whitney. Testosterone levels increased with administration of ethanol extract Karamunting leaves at dose 100 mg/kg bw (16.58 ± 2.8) and 400 mg/kg bw (16.17 ± 2.07) when compared with the control group (14.56 ± 0.8). Administration of ethanolic extract of Karamunting leaf in DM rats has an effect on testosterone levels. 
Edukasi Penggunaan Masker Dan Handsanitizer Bagi Petugas Kebersihan Di Fakultas Kedokteran ULM Siti Kaidah; Lia Yulia Budiarti; Alfi Yasmina; Farida Heriyani
Prosiding Konferensi Nasional Pengabdian Kepada Masyarakat dan Corporate Social Responsibility (PKM-CSR) Vol 3 (2020): Peran Perguruan Tinggi dan Dunia Usaha Dalam Pemberdayaan Masyarakat Untuk Menyongsong
Publisher : Asosiasi Sinergi Pengabdi dan Pemberdaya Indonesia (ASPPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (169.098 KB) | DOI: 10.37695/pkmcsr.v3i0.760

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dukasi Online Penggunaan Masker dan Hand Sanitizer bagi Tenaga Cleaning Service dan Satpam Fakultas Kedokteran Universitas Lambung Mangkurat Banjarmasi. Kota Banjarmasin termasuk salah satu kota provinsi dengan jumlah kasus covid-19 terbanyak di Indonesia. Pencegahan terhadap penularan covid-19, diantaranya dengan menerapkan protokol kesehatan berupa penggunaan masker dan mencuci tangan dengan hand sanitizer. Tenaga cleaning service dan satpam yang setiap hari bekerja di Fakultas Kedokteran Universitas Lambung Mangkurat Banjarmasin, termasuk yang berisiko dapat terpapar covid-19. Kegiatan ini bertujuan untuk memberikan pengetahuan dan pemahaman tentang penerapan protokol kesehatan dalam mencegah penularan covid-19. Sasaran kegiatan ini adalah semua tenaga cleaning service dan satpam di FK ULM Banjarmasin. Metode pelaksanaan berupa pemberian edukasi online, dengan materi tentang penggunaan masker dan hand sanitizer, serta langkah-langkah mencuci tangan yang baik dan benar. Pada kegiatan ini juga disertai pembagian masker dan hand sanitizer. Hasil kegiatan, didapatkan peningkatan pengetahuan dan keterampilan dari sasaran. Diharapkan semua peserta kegiatan dapat senantiasa menerapkan protokol kesehatan terkait covid-19 didalam rumah tangga, masyarkat dan di lingkungan kerja.
Penyuluhan Pemanfaatan Herbal Pencegah Tinea Pedis Pada Masyarakat di Wilayah Rawan Banjir lia Yulia Budiarti; Siti Kaidah; Husnul Khatimah; Erida Widyamala
Prosiding Konferensi Nasional Pengabdian Kepada Masyarakat dan Corporate Social Responsibility (PKM-CSR) Vol 4 (2021): Peran Perguruan Tinggi dan Dunia Usaha dalam Mewujudkan Pemulihan dan Resiliensi Masya
Publisher : Asosiasi Sinergi Pengabdi dan Pemberdaya Indonesia (ASPPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (215.839 KB) | DOI: 10.37695/pkmcsr.v4i0.1170

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Tinea pedis is a contagious disease caused by fungal infection and is often experienced by refugees, due to delays in treatment during floods. Kelurahan Sungai Lulut is the largest area, which was affected by the flood disaster in Banjarmasin city in January 2021. Many refugees from this area have tinea pedis disorder, so knowledge is needed for the community to recognize and utilize medicinal plants, which exist in the community along the river. and in flood prone areas. This PKM activity aims to provide counseling about types of herbs and their use to prevent tinea pedis disease in the community in Kelurahan Sungai Lulut. Extension activities are carried out offline with the target partners are housewives. Evaluation is assessed based on answers to the questionnaire before and after PKM activities. The results of the activity showed that more than 90% of the target partners could identify the types of herbs that could be used to treat tinea pedis. The conclusion of outreach activities can increase the knowledge of target partners in recognizing and utilizing types of herbs to prevent tinea pedis. It is hoped that the target partners who have received counseling can practice it, and similar activities can be further developed in other communities.
Edukasi Kesehatan Masyarakat di Bantaran Sungai Lulut Sebagai Upaya Mitigasi Bencana Banjir Husnul Khatimah; Siti Kaidah; Lia Yulia Budiarti
Prosiding Konferensi Nasional Pengabdian Kepada Masyarakat dan Corporate Social Responsibility (PKM-CSR) Vol 4 (2021): Peran Perguruan Tinggi dan Dunia Usaha dalam Mewujudkan Pemulihan dan Resiliensi Masya
Publisher : Asosiasi Sinergi Pengabdi dan Pemberdaya Indonesia (ASPPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (211.012 KB) | DOI: 10.37695/pkmcsr.v4i0.1173

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Dampak dari bencana banjir bandang yang terjadi pada awal tahun 2021 di seluruh wilayah kota Banjarmasin menyisakan lingkungan yang kurang sehat. Wilayah Sungai Lulut merupakan wilayah terbesar yang terdampak akibat bencana banjir. Hasil analisis situasi lingkungan pada masyarakat di bantaran Sungai Lulut Banjarmasin didapatkan perilaku kurang higienis dalam penerapan PHBS dalam keluarga dan menjaga kesehatan di lingkungan masyarakatnya. Bencana banjir senantiasa memiliki potensi untuk kembali terjadi, sehingga diperlukan sosialisai dan edukasi pada masyarakat untuk menerapkan PHBS dan berperan aktif dalam menjaga kesehatan lingkungannya. Kegiatan ini bertujuan memberikan pengetahuan dan pemahaman dalam menjaga kesehatan masyarakat di lingkungan bantaran sungai sebagai upaya mitigasi bencana banjir. Mitra sasaran adalah ibu-ibu rumah tangga. Metode edukasi dilaksanakan secara langsung pada mitra sasaran berupa edukasi penerapan PHBS dalam keluarga dan masyarakat, serta upaya mitigasi bencana banjir. Hasil kegiatan, didapatkan lebih dari 75% mitra sasaran paham mengenai pentingnya penerapan PHBS dalam keluarga dan masyarakat dan penerapan menjaga kesehatan dilingkungan bantaran sungai sebagai upaya mitigasi bencana banjir. Diharapkan mitra sasaran dapat menerapkan PHBS yang berkelanjutan dan turut berperan aktif dalam menjaga lingkungan bantaran sungai. Kata -kata kunci: bantaran sungai Lulut, edukasi, kesehatan masyarakat, mitigasi banjir.
Co-Authors Achmad Rofi’i Adira Zahwa Ramadhina Alfi Yasmina Alfi Yasmina Alfyonika Oktaviani Br Bukit Alievia Febriyantiningrum F. Putri Alya Nabilahsaffa Maulidinna Amalia Rahman Asnawati Asnawati Asnawati Asnawati Azhari, Nazla Puteri Azma Rozida Azzahra, Wikha Budiarman, Andi Azizah Maulidia Cibro, Impana Darwis, Yulizar Denny Agustiningsih Dewi Indah Noviana Pratiwi Didik Dwi Sanyoto Dina Ananda Wulandari Dona Marisa Dona Marisa, Dona Dona Masrisa Effiyana, Arika Eka Yudha Rahman Erida Widyamala Farida Heriyani Fauzan Muttaqien Febriyanti, Annisa Putri Finna Rahmiati Firdaus, Muhammad Reyhan FX Hendriyono Ginus Partadiredja Gunma, San Haryati Haryati Hendriyono Hendriyono, Hendriyono Hendriyono, F X Heru Prasetya Huldani Huldani Huldani Huldani Huldani Huldani Husnul Khatimah Ida Yuliana Ihsanti, Shofia Hilwa Islami, Shafira Aulia Juhairina Juhairina Kanessha Winola Sunata Khan, Muhammad Fawwaz Khatimah, Husnul Lena Rosida Lena Rosida Lia Yulia Budiarti Lia Yulia Budiarti Marsetyawan HNE Soesatyo Mawarni, Khairida Muhammad Bari NurQaedi Muhammad Bayu Fernanda Muhammad Hasan Ridhoni Muhammad Hasbi Muhammad Marwan Muthmainah, Noor Nadya Salsabila Nashrul Wathan Nasywa, Nabila Nazla Puteri Azhari Nazmyatus Sa’idah Noor Cahaya Noor Muthmainah Noor Rizka Yulia Rahmani Noorsyifa Safitri Tahir Nur Qamariah Nur Qamariah Nur Ramadhanti Cindy Levissa Oski Illiandri Oski Illiandri Putri Putri, Putri Rahmiati Rahmiati Raida Namira Rizky Nabila Febriani Rofi’i, Achmad Roselina Panghiyangani Rudiansyah, Syafina Dwiayu Ardelia Saidah Rauf Santrino, Syifa Nurafifah Sanyoto, Didik Dwi Septerini, Ditha Detiana Shelin Amanda Pusparesa Triana Norwidianti Zhasifa Khoirunnisa Suwanto