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Journal : Syntax Literate: Jurnal Ilmiah Indonesia

Efektifitas Kombinasi Ektrak Daun Pepaya (Carica Papaya L.) Dengan Ektrak Biji Pepaya (Carica Papaya L.) Terhadap Penurunan Kadar Gula Darah Pada Tikus Putih Jantan Hiperglikemik Fitriani, Hikmah; Sanif, Edial; Nurdina , Annisa Fadhilah
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i8.61568

Abstract

Hyperglycemic is a medical condition when the blood glucose level increases over the normal ranges. Hyperglycemic is one of the typical symptoms of Diabetes Mellitus (DM) although it could probably happen in the different conditions. Nowadays, the studies of epidemiology show that there seems to be the increasing of incidental numbers and DM type-2 prevalence all over the world. WHO predicts the increasing of the diabetics in Indonesia will be from 8.4 million in 2000 to 21.3 million in 2030. Aim: To know the effectiveness of giving the papaya leaf and seed extract combination in reducing the blood glucose level of male wistar strain rats induced by streptozotocin. Research Method: This research used the experimental research along with “pre and post-test control group” design and 35 male wistar strain rats (Rattus norvegicus) as the research object. The rats were divided into 2 control groups (K(+) induced by glibenclamide and K(-) by distilled water) and 3 experimental groups (P1 induced by papaya leaf extract, P2 induced by papaya seed extract, P3 induced by the combination of both extracts). Research Results: Groups showing the significant reduction of blood glucose level by paired T-test were positive control groups, P1, P2, P3 with (P<0.05). The different significant reduction of blood glucose level using one way ANOVA test along with the value (p=0.000) was showed by positive control groups, P1, P2, P3. Conclusion: Giving the combination of papaya leaf and seed extract is more effective in reducing blood glucose level than the independent one.
Uji Bakteriologis Air Minum Isi Ulang di Kecamatan Lemahwungkuk Kota Cirebon Sopiana, Anisa; Fitriani, Hikmah; Indrakusuma, Moh. Erwin
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i12.63011

Abstract

Background: Refill drinking water is widely used by the public due to its accessibility and affordability. However, improper treatment processes can lead to bacteriological contamination, particularly by Escherichia coli and Coliform bacteria, which can cause diseases such as diarrhea. Aim: To identify the bacteriological content of Escherichia coli and Coliform in refill drinking water in Lemahwungkuk District, Cirebon City. Method: This study employed a descriptive method using purposive sampling techniques. A total of 8 samples were collected from refilled drinking water depots in 4 urban villages. Each sample was tested in four repetitions using various laboratory tests, including Nutrient Agar, Mac Conkey Agar, Gram Staining, IMVIC, and TSIA for identification of Escherichia coli and Coliform bacteria. Results: Mac Conkey Agar test results showed lactose fermenters in all samples, but Escherichia coli and Coliform were not detected. Gram staining revealed the presence of Gram-positive bacteria. IMVIC test results showed Indole (-), Methyl Red (-), Voges Proskauer (-), and variable Citrate results. TSIA test showed Alkaline/Alkaline results with Gas (+) in some samples. Conclusion: No Escherichia coli or Coliform bacteria were found in any of the samples, but Gram-positive bacteria were detected, indicating microbiological contamination in refill drinking water.