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Hubungan Sosiodemografi dan Penyakit Penyerta Terhadap Nilai D-Dimer Pasien Covid-19 Michael, Michael; Ramatillah, Diana Laila; Hartuti, Silvy
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 14 No. 1 (2022): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (375.106 KB) | DOI: 10.35617/jfionline.v14i1.63

Abstract

D-dimer is a degradation of soluble fibrin which is the result of systematic degradation of vascular thrombus through a fibrinolytic mechanism. The purpose of this study was to look at sociodemographic factors and other diseases that affect the d-dimer value of COVID-19 patients. This study uses a retrospective cohort method with the collection of sampling is convenience sampling. There were 137 patients who met the study criteria. Age, BMI, blood pressure and respiration rate are sociodemographics that affect the D-dimer lab value. For comorbidities that affect the D-dimer lab value, there are CKD, anemia, hypertension and heart disease. A high D-dimer value also has a significant relationship with the severity of the COVID-19 infection. In addition, patients who died were found to have high D-dimer values. By this research, patients with high age, BMI, blood pressure and respiration rate can increase patient mortality and for comorbidities that have an important role in increasing mortality in Covid-19 patients are CKD, anemia, hypertension and heart disease.
Evaluasi Hasil Klinis Pada Tim Medis yang Mendapat Vaksinasi Booster di Rumah Sakit Bengkayang Kalimantan Barat Lukas, Stefanus; Ramatillah, Diana Laila; Aldi, Yufri; Wahyuni, Fatma Sri; Paulina, Ida; Gloria, Fransisca; Michael, Michael
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 14 No. 2 (2022): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (531.685 KB) | DOI: 10.35617/jfionline.v14i2.70

Abstract

Abstract: In reducing the risk of transmission to health workers, the Government has given the 3rd Booster Covid-19 Vaccination since August 2021. This study uses the Astra Zeneca Vaccine, Moderna Vaccine and Pfizer Vaccine. The purpose of this study was to evaluate the effectiveness of the 3rd Booster vaccine and the clinical outcomes of post-vaccination health workers at West Kalimantan Hospital. Research method Observational Cross-sectional Prospective by conducting questionnaires and interviewing health workers. Samples were taken by convenience sampling and statistical analysis of chis-square. The research instrument used a questionnaire distributed in the hospital. In the study, it was found that as many as 12.60% (14 out of 118 health workers) were infected with Covid-19. The habit that influenced the effectiveness of the 3rd booster vaccination was sunbathing (p <0.05). The low severity of health workers infected with Covid-19 after the 3rd booster vaccine can be seen from the place of treatment, namely 97% independent isolation, 60% without using antivirals and 77% without using antibiotics. The type of vitamin that is most widely used is vitamin C. Hence with this booster vaccination aims to prevent and reduce the severity of patients who contract Covid-19 after vaccination.
Pentingnya Vitamin D untuk Mencegah Beberapa Penyakit Ramatillah, Diana Laila; Indrayani, Ni Putu Kristina; Sari, Novi Triana; Virginia, Vivi; Syelvia, Fauziah Debby; Furi, Mefina Ratna; Murti, Yuliza
BERDIKARI Vol 8, No 01 (2025): Jurnal Berdikari
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/berdikari.v8i01.8405

Abstract

Vitamin D plays a crucial role in calcium and phosphorus metabolism, bone health, and immune system function. Deficiency of vitamin D in adolescents increases the risk of impaired bone growth and various chronic diseases. This community service activity aimed to enhance the understanding of 11th-grade students at SMK N 31 Jakarta regarding the importance of vitamin D in disease prevention. The method involved an interactive educational session using PowerPoint presentations, accompanied by pre-test and post-test assessments to evaluate knowledge improvement. The results showed an increase in the average post-test score to 88.07%, compared to 86.16% in the pre-test, indicating a positive improvement in students' understanding. The program effectively raised students’ awareness of the importance of vitamin D intake through sun exposure and a nutritious diet. It also demonstrated the effectiveness of interactive health education in increasing adolescents health knowledge.
Hubungan Faktor Klinis, Sosiodemografi dan Persepsi Kesehatan terhadap Lama Pengobatan Pasien Tuberkulosis Paru di Puskesmas Kota Ambon Nurhasan, Nurhasan; Ramatillah, Diana Laila
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 6, No 2 (2025): Juli
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v6i2.32399

Abstract

Tuberkulosis (TB) paru tetap menjadi tantangan besar dalam kesehatan masyarakat di Indonesia. Meskipun program pengobatan telah distandarisasi, variasi dalam lama pengobatan masih ditemukan, yang kemungkinan dipengaruhi oleh gejala klinis dan persepsi kesehatan pasien. Penelitian ini bertujuan untuk mengkaji hubungan antara gejala klinis, persepsi kesehatan, dan faktor perilaku dengan durasi pengobatan TB paru. Studi kuantitatif dengan desain potong lintang (cross-sectional) ini melibatkan 111 pasien TB paru yang memenuhi kriteria inklusi. Data dikumpulkan melalui kuesioner terstruktur dan rekam medis, kemudian dianalisis menggunakan uji korelasi Spearman, ANOVA, dan regresi linier. Dari hasil penelitian menunjukkan 60,4% laki-laki dan 39.6% perempuan dan adanya korelasi negatif yang signifikan antara gejala batuk (r = –0,358; p < 0,001), sesak napas (r = –0,327; p < 0,001), dan persepsi kesehatan (r = –0,212; p = 0,025) terhadap lama pengobatan. Variabel kelelahan juga menunjukkan pengaruh signifikan terhadap durasi pengobatan (B = 0,272; p = 0,039). Selain itu, semua variabel prediktor secara simultan memiliki hubungan yang signifikan terhadap lama pengobatan, ditunjukkan oleh nilai F hitung sebesar 3,679 dengan tingkat signifikansi < 0,001. Hasil ini menunjukan bahwa terdapat hubungan yang signifikan antara faktor klinis, sosiodemografi dan presepsi kesehatan terhadap lama pengobatan TB di Puskesmas Kota Ambon.
Pengetahuan dan Rekomendasi terhadap Pengidap Human Papillomavirus (Kanker Serviks) di Kalangan Mahasiswa Universitas 17 Agustus 1945 Jakarta Astika, Dwi; Ramatillah, Diana Laila
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 1 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jsi.v7i01.210

Abstract

Kurangnya pengetahuan masyarakat mengenai faktor risiko kanker serviks merupakan salah satu penyebab tingginya prevalensi penyakit ini. Penelitian ini bertujuan untuk menganalisis tingkat pengetahuan mahasiswa Universitas 17 Agustus 1945 Jakarta tentang penyakit hpv (kanker serviks) dan rekomendasi apa yang diberikan mahasiswa terhadap penyakit hpv (kanker serviks). Penelitian ini menggunakan metode kuantitatif dengan desain prospektif cross-sectional, melibatkan populasi mahasiswa aktif Universitas 17 Agustus 1945 Jakarta dengan sampel sebanyak 470 responden. Pengumpulan data dilakukan menggunakan kuesioner daring melalui Google Form, dengan kriteria inklusi mahasiswa aktif dan eksklusi mahasiswa yang tidak aktif. Analisis data melibatkan distribusi frekuensi dan pengujian hubungan antar variabel. Hasil penelitian menunjukkan bahwa responden perempuan memiliki tingkat pengetahuan yang lebih baik dibandingkan laki-laki, dan responden pada kelompok usia 18-25 tahun lebih aktif memberikan rekomendasi yang efektif dibandingkan kelompok usia lainnya. Kesimpulannya, terdapat hubungan signifikan antara tingkat pengetahuan mahasiswa terhadap pengidap HPV (kanker serviks), dan rekomendasi yang diberikan mahasiswa terbukti efektif dalam upaya pencegahan kanker serviks. Penelitian ini menegaskan pentingnya edukasi yang berkelanjutan untuk meningkatkan kesadaran dan pengetahuan mengenai pencegahan kanker serviks.
Evaluation of the Relationship Between Metformin Use and Kidney Function in Geriatric Patients Diagnosed with Type 2 Diabetes Mellitus in the Inpatient Ward of Level II Hospital Prof. Dr. J. A. Latumeten Ambon Tuharea, Maryanti; Ramatillah, Diana Laila
Eduvest - Journal of Universal Studies Vol. 5 No. 9 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i9.52062

Abstract

Metformin is a first-line therapy for type 2 diabetes mellitus (Type 2 DM), but its primary excretion through the kidneys raises concerns about the risk of nephrotoxicity, particularly in geriatric patients. This study aims to assess the relationship between metformin use and renal function in geriatric patients with Type 2 DM at Prof. Dr. J. A. Latumeten Ambon Level II Hospital. This study used a retrospective and prospective observational design of 150 geriatric patients receiving metformin. Data were collected through medical records and questionnaires. Kidney function parameters are assessed through GFR values and creatinine levels. The results of the study showed that the majority of respondents were aged 66–74 years (88.7%), with a prevalence of metformin use of 100%. No significant association was found between the duration of metformin use and a drastic decline in kidney function (the average creatinine value remained < 1.3 mg/dL). However, comorbidities and age were found to be factors that affect kidney function more significantly. Metformin is relatively safe to use in geriatric patients with close monitoring of renal function. The decline in kidney function is more influenced by age factors and comorbidities than by the use of metformin itself.
Co-Authors Abdul Hamid Afiyah, Evy Rosda Nur Ahmad Rofii Alviandini, Indriani Amran, Melwani Andalika, Anggie Andini, Reviana Putri Anggraeni, Yunita Dian Arani, Arani Asrianti, Asrianti Astari, Lita Tri Astiani, Rangki Astika, Dwi Audina, Sely Awlia, Siti Jumiyatul Basith, Fijar Abdul Chandra, Ferdy Delpia, Meme Dicky Wahyudi Dimyati, Bagus Prayoga Dinli, Dwi Yunisa Dirgantara, Topan Ektadinata, Sendy Natasya Via Aura Elnaem, Mohamad Elnaem, Mohamed Hasan Faradila, Sita Nur Farrukh, Muhammad Junaid Fatma Sri Wahyuni Fitri, Dhynne Risha Fitria, Neng Furi, Mefina Ratna Gloria, Fransisca Handayani, Diren Handini, Intan Dwi Hanif, Nita Aribah Hartuti, Silvy Ibrahim, Baharudin Ihsanil Husna Indrayani, Ni Putu Kristina Ipadeola, Mairo Hamid Jacob, Jelia Sinta KADIR, FITRI Kaldicson, Alno Kapahang, Praysi Kezia, Valerie Khan, Kashif Ullah Kusumawati, ⁠Ni Kadek Yuli Lestari, Fajar Ria Lukas, Stefanus Luthfiana, Farisa M L, Brigita Mahyani, Atika Rahima Mardlatillah, Mardlatillah Michael Michael Mohtar, Khumairah Muhammad Lukman Hakim, Muhammad Lukman Muhammad, Afriady Nuur Muhammad, Raihan Fadhil Munuarti Muhawia Murti, Yuliza Nabilah, Titania Nauli, Riva Jayanti Ngarso, Sofia nuralang, nuralang Nurhasan Nurhasan, Nurhasan Paulina, Ida PL, Delastri Purba, Rahelia Purdiansyah, Dewi Tamara Putri, Icha Septami Putri, Nia Basita Putri, ⁠Lidiya Rabima, Rabima Rahma, Helda Rizky, Tri Agung Rofitri, Desta Safitri, Laela Saidah, Nur Salsabila, Farras Khalda Sari, Adinda Novita Sari, Napa Purnama Sari, Novi Triana Setya Ningtyas, Maria Sheila Siboro, Linda Theresia Sinaga, Kristina SITI MARYAM Steffanie, Cindy sujana, Dewa Gede Susika, Lia Sutardi, Azzahrotul Qona'ah Ibnatus Syafrudin, Dimas Anas Syed Azhar Syed Sulaiman, Syed Azhar Syed Azhar Syed Sulaiman, Syed Azhar Syed Syelvia, Fauziah Debby Tuharea, Maryanti Virginia, Vivi Vivian, Maria Wahyudi, Agung Aji Warsono Warsono Widiawati Widiawati, Widiawati Yufri Aldi Yufrida, Yufrida Yulia Rahmawati, Yulia Yusa, ⁠Miranda Imelda Zahroh, Rahil Virginia Az Zaman Huri, Hasniza