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All Journal KOVALEN: Jurnal Riset Kimia CHEMPUBLISH JOURNAL Majalah Farmaseutik CHEESA: Chemical Engineering Research Articles Jurnal Kreativitas PKM Pharmaceutical Journal of Indonesia ALKIMIA : Jurnal Ilmu Kimia dan Terapan Jurnal ABDINUS : Jurnal Pengabdian Nusantara Jurnal Inovasi Farmasi Indonesia Community Development Journal: Jurnal Pengabdian Masyarakat Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Jurnal Farmasi dan Sains Indonesia (JFSI) Environmental and Toxicology Management (ETM) Gemakes: Jurnal Pengabdian Kepada Masyarakat FASKES : Jurnal Farmasi, Kesehatan, dan Sains Jurnal Sains dan Kesehatan JI-KES (Jurnal Ilmu Kesehatan)
Muadifah, Afidatul
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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A Natural Antiseptic Alternative in Hand Sanitizer Gel : A Combination of Miana and Kemuning Leaves Extract Muadifah, Afidatul; Tilarso, Dara Pranidya; Kristijono, Ary; Ngibad, Khoirul; Salsabila, Nabila Putri
JI-KES (Jurnal Ilmu Kesehatan) Vol. 5 No. 2 (2022): JI-KES (Jurnal Ilmu Kesehatan)
Publisher : LPPM Universitas Hafshawaty Zainul Hasan Probolinggo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33006/ji-kes.v5i2.266

Abstract

Abstrak Penggunaan gel hand sanitizer saat ini menjadi jalan keluar untuk menjaga kesehatan dan kebersihan tangan agar lebih praktis dan mudah dibawa. Penelitian ini bertujuan untuk menghasilkan antiseptik alami dari kombinasi ekstrak daun Miana dan Kemuning terhadap Staphylococcus aureus dan Escherichia coli dalam bentuk gel. Gel hand sanitizer dibuat dari kombinasi ekstrak daun miana dan kemuning yang menunjukkan daya hambat optimum terhadap bakteri Staphylococcus aureus dan Escherichia coli. Kombinasi ekstrak daun Miana dan Kemuning dibuat dalam 3 variasi konsentrasi (K1 = 5%: 15%), (K2 = 10%: 10%), dan (K3 = 15%: 5%). Formulasi gel hand sanitizer diuji kemampuannya sebagai antiseptik dan uji stabilitas fisik pada hari ke 0, hari ke 7, hari ke 14, hari ke 21, dan hari ke 28. Konsentrasi optimum dari kombinasi ekstrak daun miana dan kemuning sebagai antiseptik adalah pada kombinasi K3 = 15%: 5%. Kombinasi antiseptik alami K3 (NAK3) menunjukkan daya hambat sebesar 7,33 mm (terhadap Staphylococcus aureus) dan 09,00 mm (terhadap Escherichia coli) yang termasuk dalam kategori sedang. NAK3 memenuhi persyaratan untuk uji organoleptik, homogenitas, pH, kemampuan menyebar, dan adhesi, serta stabil selama penyimpanan..  Kata kunci: antiseptik, miana, kemuning, gel, hand sanitizer Abstract The use of hand sanitizer gel is currently a more practical and portable way to maintain health and hand hygiene. This study aims to generate a natural antiseptic from a combination of Miana and Kemuning leaves extract toward Staphylococcus aureus and Escherichia coli in gel formulation. The hand sanitizer gel is made from a combination of Miana and Kemuning leaves extract which shows optimum inhibition against Staphylococcus aureus and Escherichia coli bacteria. The combination of Miana and Kemuning leaves extracts was made in 3 variations of concentration (K1 = 5%: 15%), (K2 = 10%: 10%), and (K3 = 15%: 5%). The hand sanitizer gel formulation tested its ability as an antiseptic and on physical stability test on day 0, day 7, day 14, day 21, and day 28. The optimum concentration of the combination of Miana and Kemuning leaves extracts as an antiseptic is at a combination of K3 = 15%: 5%. The combination K3 Natural Antiseptic (NAK3) showed an inhibitory power of 7.33 mm (against Staphylococcus aureus) and 09.00 mm (against Escherichia coli) which was included in the moderate category. The NAK3 meets the requirements for organoleptic tests, homogeneity, pH, spreadability, and adhesion, and is stable during storage. Keywords: antiseptic, miana, kemuning, gel, hand sanitizer
Program Pendampingan Cara Pemilihan Produk Skincare Aman Untuk Kulit Sehat Bagi Ibu-Ibu Paruh Baya Di Desa Krebet Kecamatan Srengat Muadifah, Afidatul; Ngibad, Khoirul
Jurnal ABDINUS : Jurnal Pengabdian Nusantara Vol 5 No 1 (2021): Volume 5 Nomor 1 Tahun 2021
Publisher : Universitas Nusantara PGRI Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29407/ja.v5i1.15311

Abstract

The purpose of this community service is to increase knowledge on the skin health of middle-aged mothers in Krebet Village, Srengat District through a mentoring program for the use of safe skincare. The methods used are (1) observation and interviews; (2) Learning; (3) Assistance; and (4) Evaluation. Results: Middle-aged mothers who have used various types of skincare products obtained from doctor's clinics and cosmetic stores are 24 people. The results of learning on middle-aged mothers in Krebet Village, Srengat District of the qualitative test method and the dangers of mercury and hydroquinone in skincare products show a good value. with a percentage increase in knowledge of 67%. The results of assistance to middle-aged mothers in Krebet Village, Srengat District in stopping the use of positive skincare containing mercury and hydroquinone through replacement with skincare products that are safe for healthy skin shows good results with a 75% increase in skills so that the quality of health is better maintained.
Aktivitas Antioksidan, Kadar Flavonoid, dan Fenolik Total Cangkang Kerang Mutiara (Pinctada maxima): Antioxidant Activity, Flavonoid Content, and Total Phenolics of Pearl (Pinctada maxima) Clam Shells Ngibad, Khoirul; Muadifah, Afidatul; Sukmawati, Datin An Nisa
KOVALEN: Jurnal Riset Kimia Vol. 9 No. 1 (2023): April Edition
Publisher : Chemistry Department, Mathematics and Natural Science Faculty, Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/kovalen.2023.v9.i1.16281

Abstract

Antioxidant compounds are able to dampen or ward off free radicals. Living things including pearl mussels (Pinctada maxima) can produce secondary metabolite compounds (phenolics, alkaloids, and terpenoids). There have been no studies on the antioxidant potential, flavonoid content, and total phenolics of pearl clam shells. This study aimed to determine the antioxidant potential of pearl clam shell ethanol extract (EECKM) in vitro using the DPPH method. In addition, it aims to determine the total flavonoid and phenolic levels of EECKM. The powder of pearl mussel shells is soaked with ethanol and the filtrate is concentrated until a concentrated extract is obtained. Flavonoid and phenolic levels from EECKM were measured using a UV-Vis spectrophotometer. Measurement of antioxidant activity using the DPPH method. EECKM has a yield of 1.73%, flavonoid levels of 0 mg QE/g, and total phenolics of 4.8 mg GAE/g. The extract has the highest antioxidant activity for a concentration of 100 mg / L with a percent value of DPPH radical inhibition of 67.1%.
Efektivitas Lilin Aromaterapi Kombinasi Minyak Lavender–Kenanga terhadap Intensitas Nyeri pada Pasien Hipertensi: The Effectiveness of Lavandula latifolia-Cananga odorata Essential Oil Combination in Aromatherapy Candles on Pain Intensity in Patients with Hypertension Muadifah, Afidatul; Tilarso, Dara Pranidya; Prakoso, Jalu
Jurnal Sains dan Kesehatan Vol. 8 No. 1 (2026): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v8i1.2594

Abstract

Headache in hypertensive patients occurs as a result of vascular damage and vasoconstriction, which lead to reduced oxygen supply and increased arterial pressure. These conditions cause blood flow obstruction that may progress to tissue microinfarction and trigger anaerobic metabolism, producing lactic acid that stimulates the brain’s pain centers. This study aims to analyze the effect of aromatherapy candles containing lavender and Cananga odorata essential oils on the reduction of moderate pain intensity in patients with stage 1 hypertension. The study employed a pre-experimental design using a one-group pre–post test approach. The study population consisted of patients experiencing moderate pain due to stage 1 hypertension. Sampling was conducted using simple random sampling with a total of 52 respondents, who were proportionally assigned to four groups: a control group, treatment group 1, treatment group 2, and treatment group 3. The results showed that prior to the intervention, all respondents experienced moderate pain, and following the administration of aromatherapy candles, most respondents reported a decrease to mild pain. An independent test yielded a value of ? = 0.007 (p < 0.05), indicating a significant effect of aromatherapy candle use on the reduction of moderate pain intensity. This study demonstrates that lavender and Cananga odorata aromatherapy candles are effective as a complementary therapy for alleviating pain in hypertensive patients. Keywords:          Aromatherapy Candle, Cananga odorata, Hypertension, Lavandula latifolia, Pain   Abstrak Nyeri kepala pada pasien hipertensi terjadi akibat kerusakan dan penyempitan pembuluh darah yang menyebabkan penurunan suplai oksigen serta peningkatan tekanan arteri. Kondisi ini menimbulkan obstruksi aliran darah yang dapat berlanjut menjadi mikroinfark jaringan dan memicu metabolisme anaerob, sehingga menghasilkan asam laktat yang menstimulasi pusat nyeri di otak. Penelitian ini bertujuan untuk menganalisis pengaruh penggunaan lilin aromaterapi berbahan minyak esensial lavender dan kenanga terhadap penurunan intensitas nyeri sedang pada pasien hipertensi tahap 1. Desain penelitian menggunakan pra-eksperimental dengan pendekatan one-group pre–post test design. Populasi penelitian meliputi pasien dengan nyeri sedang akibat hipertensi tahap 1. Teknik pengambilan sampel menggunakan simple random sampling dengan total 52 responden, yang dibagi secara proporsional ke dalam empat kelompok penelitian: kelompok kontrol, kelompok perlakuan 1, kelompok perlakuan 2, dan kelompok perlakuan 3. Hasil penelitian menunjukkan bahwa sebelum intervensi, seluruh responden mengalami nyeri sedang, dan setelah pemberian lilin aromaterapi sebagian besar responden mengalami penurunan menjadi nyeri ringan. Uji independent test menunjukkan nilai ? = 0,007 (p < 0,05), sehingga dapat disimpulkan terdapat pengaruh signifikan penggunaan lilin aromaterapi terhadap penurunan intensitas nyeri sedang. Penelitian ini menegaskan bahwa lilin aromaterapi lavender dan kenanga efektif sebagai terapi komplementer dalam meredakan nyeri pada pasien hipertensi. Kata Kunci:         Hipertensi, Kenanga, Lavender, Lilin Aromaterapi, Nyeri  
Co-Authors Arif Santoso Choirul Huda Danar Danar Datin An Nisa Sukmawati Etonihu, Anayo Christian Handaru, Windu Hariani Nurjanah, Mutia Ima, Ernisa Afidatul Imanez, Ketzia Adrian Indah Pratiwi, Putri Indra Lasmana Tarigan Jannah Triarini, Lailatul Jovanncha, Czellicya Karel Damayanti, Novita Kharisma, Mei Nabila Revina Kholifah, Siti Nurriyatul Khusna, Mursyidah Lathifatul Kristijono, Ary Kumalasari, Nurul Chamidah Lestari, Nasa Bela Dwi Lintang, Anggun Maida, Margarita Claudya MARTHA, RAHMA DIYAN Mashudi Mashudi Ngibad, Khoirul Nurjanah, Mutia Hariani Parbuntari, Hesty Prakoso, Jalu Pratiwi, Putri Indah Putri, Amalia Eka Rahma Diyan Martha Rahmawati, Desti Linda Dwi Rizki Amalia, Laily Safitri, Yunita Diyah Salsabila, Nabila Putri Sandi Mahesa Yudhantara Sari, Trianita Sowe, Momodou Salieu Sulastri Sulastri Susanto, Nindita Clourisa Clourisa Amaris Tiara Aninditha Tilarso, Dara Tilarso, Dara Pranidya Ulayya, Nida Asma Ummah, Ratih Salimil Warni, Tri Wiwik Handayani