Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : Biospecies

- Uji Efektivitas Ekstrak Bunga Pepaya (Carrica papaya L.) Terhadap Kadar Gula Darah Mencit (Mus musculus L.) Jantan Yang Diinduksi Sukrosa: Uji Efetivitas Ekstrak Bunga Pepaya (Carrica Papaya L.) Terhadap Kadar Gula Darah Mencit (Mus Musculus L.) Jantan Yang Diinduksi Sukrosa Marpaung, Febri Sri; Tampubolon, Ester Juanita br.; Andika, Muhammad Insan; Lubis, Yolanda Eliza Putri; Mutia, Maya Sari
Biospecies Vol. 14 No. 1 (2021): Januari 2021
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/biospecies.v14i1.11175

Abstract

The papaya (Carica papaya L) flower contain flavonoids, tannins, and triterpenoid steroids which function as antidiabetic. This study was conducted to determine the antidiabetic effect of papaya (Carica papaya L) flower extract on sucrose-induced male mice. In this study, mice were made diabetic by inducing them with sucrose at a dose of 160 mg/kg BW. A total of 25 mice were grouped homogeneously into 5 groups, consisting of a negative control group (CMC 0.5%), a positive control group (no administration), a group with a dose of 200 mg/kg BW, a group with a dose of 400 mg/Kg. BW, and the group with a dose of 500 mg/Kg BW. Measurement of blood sugar levels of mice was carried out before administration of sucrose, after administration of sucrose and after administration of papaya flower extract. The results showed that the three doses had an antidiabetic effect, and the administration of papaya flower extract at a dose of 200 mg/Kg BW showed a better effect than the negative control.
- Uji Efektivitas Ekstrak Etanol Kulit Jeruk Sunkist (Citrus sinensis (L.) Osbeck) Terhadap Kadar Gula Darah Tikus Wistar (Rattus norvegicus) dengan Hiperkolesterolemia yang di Induksi Streptozotocin. : UJI EFEKTIVITAS EKSTRAK ETANOL KULIT JERUK SUNKIST (Citrus sinensis (L.) Osbeck) TERHADAP KADAR GULA DARAH TIKUS WISTAR (Rattus norvegicus) DENGAN HIPERKOLESTEROLEMIA YANG DI INDUKSI STREPTOZOTOCIN Depari, Sania Angelisa F; Rambe, Daffa Jihan Azmi; Meilando, Rifki; Lisya, Cut; Mutia, Maya Sari; Lubis, Yolanda Eliza Putri
Biospecies Vol. 14 No. 1 (2021): Januari 2021
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/biospecies.v14i1.11250

Abstract

The Condition of high blood sugar levels in people with diabetets appears to trigger an increase in LDL and decrease HDL level where in people with diabetes the energy obtained by the body comes from the decomposition of fat and protein metabolism.”Sunkist orange peel (Citrus sinensis (L.) Osbeck) is reported to have antidiabetic, anti-hypercholesterolemia, anti-inflammatory and antioxidant activities. This study aims to find out the effectiveness of Sunkist orange peel ethanol extract (Citrus sinensis (L.) Osbeck) on blood sugar levels at doses of 500, 750 and 1000 mg/kgBB. This study used the True Experimental Pre-Test and Post-Test Control Group as research design where sunkist orange peel was extracted by maceration method and was given orally for 14 days to streptozotocin induced wistar rat with hypercholesterolemia. Statistical test results showed that ethanol extract of Sunkist orange peel was able to lower blood sugar levels and cholesterol levels of h streptozotocin induced wistar rat with hypercholesterolemia (p<0.05). The most effective dose of Sunkist orange peel ethanol extract in lowering blood sugar levels and cholesterol levels of streptozotocin induced wistar rat with hypercholesterolemia is 1000mg/kgBB.
Co-Authors Andika, Muhammad Insan Annisa, Elvia Arviandi, Rizki Bangun, Primta Br Sitepu, Rachel Maria Cruz Jovanca Chairul, Muhammad Damayanti, Etha Wilda Hasiani Depari, Sania Angelisa F Dewani, Yunita DEWI SARTIKA Dewi, Silvi Tiara Diana S, M Putri Elmiam, Dwi Fadillah, Qori Faridahanum, Faridahanum Fau, Solinia Kifami Yohana Maria Vianne Fitrisia, Rina Ginting, Chrismis Novalinda Girsang, Ermi Gunawan, Robby Gurusinga, Fransisco Bastanta Gusbakti Rusip Hamsi, Ulpah Zahara Harahap, Safriani Hasibuan, Patimah Fitriansyari Henny Henny, Henny Hutagalung, Caroline Febrina Irwanda, Desi Danilah Kurniawan, Gracella Verren Lie, Maylia Lina, Juliana Lister, INE Lisya, Cut Manalu, Cici Valentina Mangkuanom, Adrian Saleh Marpaung, Febri Sri Marpaung, Febri Sri Astuti Meilando, Rifki Meutia, Rena Michiko, Michiko Monica, Veny Nabila, Putri Nadia, Felanda Ahsan Napitupulu, Olivia Des Vinca Albahana Nasution, Ali Napiah Nasution, Tamimi Badzlina Natali, Oliviti Nathasia, Ingee Nurhady, Fahira Zahra Putra, Ananda Rahmat Putri, Indah Juwita Dwi Putri, Shafyra Mahdyah Ramadhini, Amelya Putri Rambe, Daffa Jihan Azmi Razoki, Razoki Ritonga, Lapita Sarkiah Salsabila, Dinda Ayu Sanjaya, Erfan Sari, Ajeng Mestika Silitonga, Impola Dinita Felicia Sipayung, Yelvreza Rastiani Siregar, Lisdawaty Sitepu, Bintang Darma M Suandy, Suandy Suhartina Suhartina, Suhartina SUHARTOMI . Sulistijanto, Eddy Suyono, Tan Tambunan, Adrian Nurrachman Tambunan, Andika Zayani Tampubolon, Ester Juanita Tampubolon, Ester Juanita br. Tio, Susanthy Widya Yanti Sihotang Winato, Brigad Mahardika Yolanda Eliza Putri Lubis Yulizal, Ok