Article Per Year (5 Year)
p-Index From 2021 - 2026
3.109
P-Index
This Author published in this journals
All Journal Jurnal Kedokteran Brawijaya Jurnal Keperawatan Priority Jurnal Prima Medika Sains Jurnal Aisyah : Jurnal Ilmu Kesehatan Budapest International Research in Exact Sciences (BirEx Journal) PRIMER (Prima Medical Journal) Jurnal EduHealth TRILOGI: Jurnal Ilmu Teknologi, Kesehatan, dan Humaniora Buletin Kedokteran dan Kesehatan Prima E-Jurnal Manajemen Trisakti School of Management (TSM)
Fioni, Fioni
Universitas Prima Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Physics Public Health Social Sciences Transportation Veterinary Other

Published : 21 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 21 Documents
Search

 1   2   3 
Faktor Risiko Kejadian Psoriasis pada Pasien Rawat Jalan di RS Royal Prima Medan: Studi Case-Control Xinyuan, Guo; Suci, Tri; Liena, Liena; Fioni, Fioni
TRILOGI: Jurnal Ilmu Teknologi, Kesehatan, dan Humaniora Vol 7, No 1 (2026)
Publisher : Universitas Nurul Jadid

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33650/trilogi.v7i1.14812

Abstract

Psoriasis is a chronic immune-mediated inflammatory disease characterized by keratinocyte hyperproliferation and persistent systemic inflammation, and is associated with genetic predisposition and metabolic comorbidities. Identifying its determinants is important to improve prevention and clinical management. This study aimed to analyze the association between age, body mass index (BMI), smoking history, family history of psoriasis, diabetes mellitus, and hypertension with the occurrence of psoriasis in outpatients at the Dermatology and Venereology Clinic of Royal Prima Hospital, Medan, from 2024 to 2025. This study used an analytical observational design with a retrospective case-control approach. A total of 210 respondents were included, consisting of 105 cases (patients diagnosed with psoriasis) and 105 controls (patients without psoriasis). Controls were selected from patients attending the same clinic during the same period without a diagnosis of psoriasis to ensure comparability and minimize selection bias. Data were obtained from medical records and analyzed using the Chi-square test and binary logistic regression. Bivariate analysis showed that age ≥45 years, BMI ≥25 kg/m², smoking history, family history of psoriasis, diabetes mellitus, and hypertension were significantly associated with psoriasis (p < 0.05). Multivariate analysis revealed that age ≥45 years (Adjusted OR = 1.85; 95% CI: 1.02–3.35; p = 0.042), BMI ≥25 kg/m² (Adjusted OR = 1.98; 95% CI: 1.09–3.61; p = 0.024), family history of psoriasis (Adjusted OR = 6.45; 95% CI: 2.82–14.75; p < 0.001), and diabetes mellitus (Adjusted OR = 2.41; 95% CI: 1.05–5.54; p = 0.037) remained significant predictors. Family history of psoriasis was identified as the most dominant determinant. These findings highlight the importance of early screening in high-risk individuals, particularly those with a family history of psoriasis and metabolic comorbidities, to support timely detection and improve clinical management. In conclusion, genetic and metabolic factors, along with age, are key determinants of psoriasis occurrence.
Co-Authors Angkasa, Alexander Arhani, Adli ARILYN, ERIKA JIMENA Asyrun Alkhairi Lubis Aulia, Hilda Rafni Binarwan Halim Chen Wei Dewi Riastawaty Edy Fachrial Erwina Putri, Riri Fibrini, Dewi Florenly Florenly Florenly Florenly Florenly Florenly Girsang, Ermi Janice Janice Ji Junfeng Jiang Fan Johannes Bastira Ginting Khainir Akbar, Khainir Li Sha Li Wei Liana Liana Liena Liena Liena, Liena Lister, I Nyoman Ehrich Lizar, Budi Septhian Lumbantobing, Christina JRE Malau, Reghita Claudia Meutia, Rena Nardi, Leo Nasution, Ali Napiah Nasution, Chairul Radjab Pratama , Irza Haicha Rahimi, Armon Rahma Sari Rapael Ginting Razoki, Razoki Reh Malem br Karo Rizal Rizal Sari, Juwita Purnama Simatupang, Veronica Triwindari Sinurat, Jhon Patar Siregar, Lidya Siregar, Lusyana Suci, Tri Tarigan, Antje Irmella WAHYU WIDOWATI Widya Yanti Sihotang Wienaldi, Wienaldi Xinyuan, Guo