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Gambaran kadar sebum kulit wajah pada mahasiswa Fakultas Kedokteran Universitas Tarumanagara penderita akne vulgaris Priscilla Clara Agatha; Linda Julianti Wijayadi; Sony Sugiharto
Tarumanagara Medical Journal Vol. 3 No. 1 (2021): TARUMANAGARA MEDICAL JOURNAL
Publisher : Fakultas Kedokteran Universitas Tarumanagara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24912/tmj.v3i2.11755

Abstract

Akne vulgaris (AV) adalah suatu peradangan kronik yang terjadi pada unit pilosebasea. Insidensi AV tersering pada usia 15-18 tahun. Lesi AV dapat ditemukan pada wajah, leher, dada, dan punggung. Salah satu patofisiologi terpenting AV adalah peningkatan produksi sebum oleh kelenjar pilosebasea. Studi dekriptif dengan desain potong lintang dilakukan untuk mengetahui kadar sebum kulit wajah pada 61 mahasiswa Fakultas Kedokteran Universitas Tarumanagara yang menderita AV. Pengukuran kadar sebum dilakukan dengan menggunakan sebumeter pada alat analisis kulit Runve HL-611. Hasil studi didapatkan mayoritas subyek sebesar 43 (70.5%) orang memiliki AV derajat sedang dan 35 (57.4%) orang memiliki tipe lesi AV papul, pustul, dan komedo.  Hasil gambaran kadar sebum kulit wajah didapatkan mayoritas subyek memiliki kadar sebum kulit wajah berminyak dan normal di area dahi dengan kuantitas masing-masing sebesar 19 (31.1%) orang dan  kadar sangat berminyak di area pipi dan dagu dengan kuantitas sebesar 30 (49.2%) orang di area pipi kanan, 33 (54.1%) di area pipi kiri dan 32 (52.5%) orang di area dagu.
Gambaran kadar hidrasi kulit sebelum dan sesudah fototerapi pada pasien Poli Kulit dan Kelamin di RS Sumber Waras Jakarta Winnia Tanely; Linda Julianti Wijayadi; Sari Mariyati Dewi Nataprawira
Tarumanagara Medical Journal Vol. 3 No. 2 (2021): TARUMANAGARA MEDICAL JOURNAL
Publisher : Fakultas Kedokteran Universitas Tarumanagara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24912/tmj.v4i1.13734

Abstract

Kadar hidrasi kulit merupakan salah satu parameter kesehatan kulit yang sangat dipengaruhi natural moisturizing factor (NMF) dan lipid interseluler. Terjadinya gangguan pada kedua komponen tersebut, baik yang disebabkan oleh faktor intrinsik maupun ekstrinsik akan menyebabkan penurunan kadar hidrasi kulit. Xerosis kutis atau kulit kering menimbulkan pruritus dan inflamasi. Fototerapi dengan narrow band ultraviolet B (NBUVB) yang digunakan untuk menurunkan inflamasi dan pruritus pada penyakit kulit dapat menyebabkan kadar hidrasi kulit menurun. Tujuan studi ini adalah mengetahui gambaran kadar hidrasi kulit pada subjek yang mendapatkan fototerapi narrow band UVB di Poli Kulit dan Kelamin Rumah Sakit Sumber Waras serta pengaruh dosis dan durasi fototerapi terhadap kadar hidrasi kulit. Studi ini merupakan studi deskriptif dengan desain potong lintang pada 10 subjek yang diambil menggunakan teknik total sampling. Subyek merupakan pasien poli kulit dan kelamin RS Sumber Waras yang datang selama periode Januari - Agustus 2020. Pengumpulan data dilakukan menggunakan kuesioner, data rekam medis dan pengukuran kadar hidrasi kulit menggunakan korneometer. Hasil studi didapatkan kadar hidrasi kulit yang sangat kering pada seluruh subjek sebelum fototerapi dan kadar hidrasi kulit makin menurun setelah dilakukan fototerapi. Fototerapi narrow band UVB menurunkan kadar hidrasi kulit, namun tidak dipengaruhi oleh dosis dan durasi pemberian fototerapi.
Overview of workers hand skin hydration levels on tofu maker at the tofu factory in Matraman district, East Jakarta Fitri Rahmawati; Linda Julianti Wijayadi; Sari Mariyati Dewi N
Science Midwifery Vol 10 No 4 (2022): October: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v10i4.746

Abstract

The parameters of human skin health can be assessed from the level of skin hydration. Skin hydration level is the water content in the stratum corneum which is strongly influenced by natural moisturizing factor (NMF) and intercellular lipids. These components can be disrupted when exposed to irritants, such as detergents, too acidic substances, and so on. This condition can cause a decrease in skin hydration levels and becomes inactive, thereby it increases the skin's sensitivity to exogenous factors and infections. Traditional tofu factory workers are workers who have a risk of experiencing a decrease in skin hydration levels due to frequent exposure to tofu-making ingredients with an acidic pH. In Matraman Sub-district, East Jakarta, there are several tofu factories with the manufacturing process that is still processed traditionally. This descriptive observational study with a cross-sectional design aims to determine the overview of hand skin hydration levels in tofu-making workers located in the traditional tofu factory at Matraman District, East Jakarta. So that the workers and factory owners are expected to improve the quality of their workers. Data were obtained by measuring skin hydration levels in 100 study subjects using SK-IV corneometer and filling out questionnaires. Results: an overview of the skin hydration levels of right-handed and left-handed subjects with an average of 20,42% (very dry skin). The average level of skin hydration was lowest in the 60-70 year age group (19,35%), and in the 20-30 year age group (21,65%) and the male group had higher levels (20,59%). Level measurement at the hand location was obtained very dry skin category on the back of the right hand (100%). The more frequent of the frequency exposure to chemicals, the lower the hydration level of the skin (20,08%).
The Role of Herbal Plant Essential Oils in the Treatment of Acne Vulgaris Kelvin; Linda Julianti Wijayadi
Science Midwifery Vol 10 No 4 (2022): October: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v10i4.764

Abstract

Acne vulgaris (AV) is a disease of the pilosebaceous unit that often occurs at the age of 15 to 40 years. Various factors can influence this disease such as abnormal keratinization, microbial colonization, increased sebum production and complex inflammatory mechanisms. Essential oils can be used as an alternative therapy for AV. Various kinds of essential oils which are natural aromatic compounds from herbal plants, have long been known to help cure AV. This is because of the various beneficial compounds contained in each essential oils. The effects are varied such as anti-inflammatory, antioxidant and antimicrobial which will affect the healing mechanism of AV. This literature review discusses the role of essential oils from kaffir lime (Citrus hystrix), cinnamon (Cinnamomum), tea tree (Melaleuca alternifolia), lemongrass (Cymbopogon citratus (DC) Stapf. and Cymbopogon flexuosus), oregano (Origanum vulgare) and lavender (Lavandula angustifolia) against AV treatment.
The Role of Essential Oils on Improving Elderly Skin Hydration Linda Julianti Wijayadi; Kelvin Kelvin
Science Midwifery Vol 10 No 4 (2022): October: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v10i4.769

Abstract

Skin hydration has an important role in various diseases of the elderly. Skin hydration is determined by two factors, namely the ability of the stratum corneum (SC) to retain water due to natural moisturizing factors and the barrier function of the intercellular lipid lamellar structure and tight junctions. Several parameters are usually used for skin hydration, such as surface water content (SWC) and trans-epidermal water loss (TEWL). With age, several changes in the skin affect hydration, including changes in the cellular and intercellular lipid matrix, skin pH, SC protease enzymes, decreased sebaceous and sweat gland activity, and decreased estrogen levels in women. Therefore, a moisturizer is needed to minimize the unwanted effects of some of these changes. Selection of the type of moisturizer is very important for the elderly, especially moisturizers with antiseptic, antibacterial, and antioxidant effects are highly recommended. The ability of essential oils as components of moisturizers has been proven in various studies. Essential oils can improve the function of the epidermal barrier and help prevent transepidermal water loss. Therefore, this literature review discusses the role of various essential oils, namely green tea oils (Camellia sinensis or Camellia assamica), virgin coconut oils (Cocos nucifera L.), evening primrose oils (Oenothera paradoxa), grape seed oils (Vitis vinifera L.) .), rosemary oils (Rosmarinus officinalis L.), immortelle oils (Helichrysum italicum), and cannabis seeds oils (Cannabis sativa L.) on improving skin hydration in the elderly.
Effectiveness of Helichrysum italicum Essential Oil on Wound Healing Linda Julianti Wijayadi; Kelvin Kelvin
Journal of Food and Pharmaceutical Sciences Vol 10, No 2 (2022): J.Food.Pharm.Sci
Publisher : Institute for Halal Industry and System (IHIS) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.5324

Abstract

Helichrysum italicum essential oils (EOs) has long been known as a medicinal agent, especially in wound healing. This is inseparable from the chemical compounds contained in it, such as abundant monoterpenes and sesquiterpenes. The purpose of this systematic review is to examine various studies on the effectiveness of H. italicum EOs on wound healing. Research data searches were conducted through Google Scholar, Proquest, Science Direct, SpringerLink, Wiley Online Library, Taylor & Francis Online and PubMed over the last 10 years by following inclusion and exclusion criteria. Obtained as many as 11 studies that match the criteria. Based on the review of these studies, it was found that H. italicum EOs has good wound healing abilities when viewed from various aspects such as its chemical components, biological activity and its effect on injured body tissues. These chemical components vary in type and amount because they are influenced by various aspects. Biological activities such as antioxidant, antimicrobial, and anti-inflammatory effects have also been shown to be contained in this oil because it affects various phases of wound healing, namely hemostasis, inflammation, proliferation and remodeling phases. This is also inseparable from the accuracy of the type of vehicle used.
Nevus Melanositik Kongenital Raksasa dan Kelainan Kongenital Ekstremitas pada Bayi Baru Lahir Cayadi Sidarta Antonius; Linda Julianti Wijayadi
Cermin Dunia Kedokteran Vol 48 No 1 (2021): Infeksi COVID-19
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v48i1.31

Abstract

Nevus Melanositik sejak lahir ditemukan pada satu persen anak di dunia dengan ukuran bervariasi. Salah satu varian nevus melanositik yang sangat jarang, berukuran sangat besar, yakni Nevus Melanositik Kongenital Raksasa (NMKR). Pada tulisan ini dilaporkan kasus NMKR disertai kelainan kongenital ekstremitas. Seorang bayi perempuan lahir di puskesmas dengan partus spontan dirujuk ke IGD, 3-4 jam setelah lahir. Terdapat bercak hitam di area perut, punggung, dan paha. Didapatkan juga perbedaan panjang tungkai, serta hanya ada 3 jari di kaki kanan. Tatalaksana diberi pelembap. Kasus ini jarang; diperlukan konsultasi dan observasi teratur untuk meningkatkan dan memperpanjang harapan hidup. Melanocytic Nevus since birth is found in one percent of children in the world with variable severity. One of the rare variant is very large melanocytic nevus variant called Giant Congenital Melanocytic Nevus (GCMN). This paper reported a case of GCNM accompanied with congenital abnormalities of the extremities. A baby girl who was born spontaneously in a clinic, was referred to the emergency department about 3-4 hours after her birth. The abnormalities were black spots in the abdominal area, back, and thighs. The patient also had different length of legs differences with only 3 toes on right foot. The patient was given moisturizer. GCMN case accompanied with congenital limb abnormalities is rare; regular consultation and observation are required to improve and prolong survival.
Peran Helichrysum italicum sebagai Anti Inflamasi pada Terapi Dermatitis Atopi Aryananda Haris Wardoyo; Andrew Soerijadi; Linda Julianti Wijayadi
Cermin Dunia Kedokteran Vol 49 No 12 (2022): Dermatologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v49i12.331

Abstract

Dermatitis atopik (DA) merupakan salah satu penyakit inflamasi kulit kronis yang terjadi dengan karakteristik kulit kering, berskuama, dan eritema. Pengobatan DA selain terapi konvensional atau penggunaan biologic agent, diteliti juga pengobatan alternatif menggunakan bahan alami; di antaranya Helichrysum italicum. Manfaat H. italicum adalah sebagai anti-mikroba, anti-inflamasi, anti-viral, anti-oksidan, dan anti-larvisidal. Sudah ada aplikasi H. italicum sebagai terapi tambahan dan alternatif penderita DA. Atopic dermatitis (AD) is a chronic inflammatory skin disease that occurs with dry, scaly, and erythematous skin characteristics. AD treatment apart from conventional therapy or the uses of biologic agents, alternative treatments using natural ingredients are also being studied; including Helichrysum italicum. The benefits of H. italicum are as anti-microbial, anti-inflammatory, anti-viral, anti-oxidant, and anti-larvicidal. There is already an application of H. italicum as an additional and alternative therapy for AD sufferers.
Uremic Frost - Kelainan Kulit pada Gagal Ginjal Kronik Nathasia; Linda Julianti Wijayadi
Cermin Dunia Kedokteran Vol 47 No 9 (2020): Infeksi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v47i9.567

Abstract

Uremic frost merupakan kelainan kulit yang jarang, karena ditemukan pada pasien gagal ginjal kronik yang belum menjalani hemodialisis. Kelainan ini ditandai dengan lapisan putih kekuningan akibat kristal urea yang mengendap di permukaan kulit. Seorang wanita 44 tahun datang dengan keluhan utama kulit kering, bersisik, dan gatal seluruh tubuh sejak 1 bulan. Pasien baru didiagnosis gagal ginjal kronik. Pada pemeriksaan dermatologi didapatkan makula hiperpigmentasi, berbatas tegas, multipel, ukuran lentikular-plakat, dan krusta putih kekuningan. Tatalaksana dermatologi uremic frost adalah dengan pelembap dan antihistamin oral, pengobatan lebih lanjut untuk penyakit ginjal yang mendasari. Uremic frost is a rare skin disorder, found in chronic kidney failure patients who have not undergone hemodialysis. This disorder is characterized by yellowish white layer on the skin surface due to urea crystals. A 44-year-old female patient presented with dry, scaly, and itchy skin on the whole body in the last 1 month. The patient has just been diagnosed with chronic kidney failure. Dermatological examination revealed hyperpigmented macules, well-defined, multiple, lenticular-placard size and also a yellowish-white crust. Management in dermatology is with moisturizers and oral antihistamines, further treatment should be given to underlying kidney disease.
The Effect of Natural Essential Oil Depigmenting Agent for Alternative Treatment of Melasma Linda Julianti Wijayadi; Kelvin Kelvin
Journal of Food and Pharmaceutical Sciences Vol 11, No 1 (2023): J.Food.Pharm.Sci
Publisher : Institute for Halal Industry and System (IHIS) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.6131

Abstract

Melasma, known as a hyperpigmentation disorder, is more common in women of childbearing age with Fitzpatrick IV-VI skin types. Various factors of this disease, namely genetic factors, UV exposure, hormonal, thyroid disease, pregnancy, and drugs. The best treatment for melasma is with 2 – 4% hydroquinone, but because of the side effects, alternative treatments are mostly used for melasma. One of them is with essential oils. Essential oils have been investigated as depigmenting agents because of their anti-tyrosinase potential. In this literature, it is proven that the essential oils of sage (Salvia), hedgenettle / woundwort (Stachys), lavender (Lavandula), tea tree (Melaleuca alternifolia), cinnamon (Cinnamomum), mountain tea (Sideritis), pomelo (Citrus grandis ( L) Osbeck), and kaffir lime (Citrus hystrix DC) are effective against melasma. The purpose of this literature is to discuss the various effects of essential oils that can be used as depigmentation agents in the alternative treatment of melasma.