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All Journal CHEMPUBLISH JOURNAL Jurnal Farmasi Sains dan Komunitas PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Ilmu Kefarmasian Indonesia JURNAL FARMASIMED (JFM) SANITAS: Jurnal Teknologi dan Seni Kesehatan Jurnal Peduli Masyarakat MEDIC MEdical Dedication Yayasan Cita Cendikiawan Al Khwarizmi Jurnal Abdimas Kartika Wijayakusuma Journal of Pharmaceutical Care and Sciences Pharmaceutical Sciences and Research (PSR) JOURNAL OF CHEMICAL NATURAL RESOURCES (JCNaR) Jurnal Karya Abdi Masyarakat Sciences of Pharmacy Electronic Journal Scientific of Environmental Health And Diseases Sinteza Jurnal Pengabdian Harapan Ibu (JPHI) Journal of Pharmaceutical and Sciences. Bencoolen Journal of Pharmacy Jurnal Kefarmasian Indonesia Pharmacon: Jurnal Farmasi Indonesia Jurnal Abdimas Kesehatan
Maharini, Indri
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Optimization Formula and SPF Test of Lotion from Essential Oil of Patchouli Leaves (Pogostemon cablin Benth.) Anjaly Rizkya Fazariana; Fathnur Sani K; Indri Maharini
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 22, No 2 (2025)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.008439

Abstract

An increase in the ultraviolet (UV) index poses severe health risks by inducing harmful effects on the skin, such as sunburn, erythema, skin darkening, premature ageing, and skin cancer. These risks are mitigated through sunscreens with high Sun Protection Factor (SPF) values (15). Natural sources of high SPF include patchouli leaf essential oil, which contains flavonoids. Flavonoid compounds with double bonds can absorb UV-A and UV-B rays, protecting against their harmful effects. The purpose of this study was to find the best formula and observe its impact on the physical characteristics of the preparation and SPF activity. Formula optimization used Design Expert software 13 with the simplex lattice design method. The optimized variables were TEA and stearic acid as emulsifying agents. The results of the optimum formula composition consisted of 4% TEA and 5% stearic acid. The optimum skin protection lotion preparation has a yellow color, a distinctive smell of patchouli oil, a semi-solid shape and a thick texture. The pH parameters of 7.7±0.09, adhesion of 2.34±0.06 seconds, spreadability of 6.85±0.02 cm and viscosity of 4503.3±219.39 Cp. Patchouli leaf essential oil and lotion have ultra-category SPF values with oil SPF value of 27.86±1.07 and lotion preparation of 27.65±1.75 preparation is also homogeneous with pH parameters of 7.7±0.09, adhesion of 2.34±0.06 seconds, spreadability of 6.85±0.02 cm and viscosity of 4503.3±219.39 Cp. Patchouli leaf essential oil and lotion have ultra-category SPF values with oil SPF value of 27.86±1.07 and lotion preparation of 27.65±1.75.
Formulasi Nanopartikel Ekstrak Buah Naga (Hylocereus Polyrhizus) Sebagai Zat Warna Sediaan Lipstik Maharini, Indri
Chempublish Journal Vol. 2 No. 1 (2017): Chempublish Journal
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (364.582 KB)

Abstract

Lipstick merupakan sediaan dekoratif yang banyak digunakan oleh wanita. Dalam sediaan ini biasanya mengandung bahan pewarna sintetik. Penggunaan lipstick sangat mungkin tertelan bersama ludah, makanan dan minuman oleh karena itu sangat berbahaya jika dalam sediaan lipstik mengandung zat pewarna berbahaya. Zat warna alami dibutuhkan keberadaannya karena dianggap lebih aman dibandingkan dengan pewarna sintetik. Buah naga merupakan tanaman yang mengandung betasianin. Senyawa ini merupakan zat warna merah pada buah yang berkhasiat sebagai antioksidan. Antioksidan diperlukan dalam formulasi sediaan lipstick untuk mencegah teroksidasinya lemak dari basis yang dapat menyebabkan bau tengik pada sediaan. Dalam penelitian ini akan dilakukan formulasi nanopartikel ekstrak buah naga. Nanopartikel mampu mencegah terjadinya migrasi zat warna pada sediaan lipstick. Metode pembuatan sediaan nanopartikel menggunakan gelasi ionic. Komposisi formula nanopartikel buah naga yaitu : eksrak cair buah naga konsentrasi 1 g/ 25 ml 4 bagian, larutan kitosan 1 mg/ml 1 bagian dan 0,05 bagian Na TPP konsentrasi 0,4 mg/ml. hasil sediaan nanopartikel menunjukkan larutan opalesen dan stabil dalam penyimpanan. Sediaan lipstick berkonsisitensi rendah dengan warna pink pucat. Kata kunci: nanopartikel, buah naga, antioksidan, zat warna, lipstik
Antibacterial Activity Test of Gel Toothpaste from Cinnamon Leaf Essential Oil ( Cinnamomum burmanni Blume.) Against Staphylococcus aureus Bacteria Chintya Dwiyunia Putri; Elisma Elisma; Indri Maharini
Pharmacon: Jurnal Farmasi Indonesia Vol. 21 No. 1 (2024)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v21i1.4821

Abstract

Cinnamon leaf essential oil can inhibit the growth of Staphylococcus aureus bacteria because it contains cinnamaldehyde and eugenol compounds, which function as antibacterials. Staphylococcus aureus is a bacteria involved in various infections in the mouth and human body. This research aims to formulate cinnamon leaf essential oil into a gel toothpaste preparation by differentiating the concentration of cinnamon leaf essential oil as an active ingredient and testing its antibacterial activity against Staphylococcus aureus bacteria. The concentration of active ingredients in formula I is 0.5%, in formula II, 1%, and in formula III, 1.5%. Evaluation of the physical properties of gel toothpaste preparations includes organoleptic, homogeneity, spreadability, pH, viscosity, foam ability, stickiness, and antibacterial activity test against S. aureus using the well diffusion method. The results of the organoleptic and homogeneity evaluations were analyzed descriptively. In contrast, the spreadability, pH, viscosity, foam height, adhesion, stability, and antibacterial activity tests were analyzedstatistically using One-way ANOVA. Organoleptic test results showed yellowish white (FI), light yellow (FII), and yellow (FIII); all three formulas had a characteristic smell of essential oils and were semisolidand homogeneous. The spreadability test results ranged from 5-5.90 cm, pH value from 5.05-5.47, viscosity value from 31,980-43,900 Cp, foam ability from 9-14 mm and adhesion value from 05.84-08.83 seconds. The antibacterial activity test results for formulas I and II formed an inhibition zone in the strong category, while formula III formed an inhibition zone in the powerful category.
Co-Authors ., Elisma Afriana, Nadila Amalya Nasution, Riska Anjaly Rizkya Fazariana Arrahman, Ghery Astuti, Novita Tri Bilia Ayu Septiana Budi Aswin Cathelya, Bunga Chintya Dwiyunia Putri Cut Mutia Diah Tri Utami Diky Okta Yudha Putra Dinofitri, Hanifah Dominica, Dwi Dwi Puspita, Puspa Efendi, M. Rifki Eka Putra, Nofrans Elisma Elisma Elisma Elisma Elisma Elisma Elisma Fitri, Zahwa Syuhada Fitrianingsih Fitrianingsih Fitriyanti Hanifah, Risa Harahap, Huntari Harmonyzha, Giga K. Havizur Rahman Humaryanto, Humaryanto Idamanda, Rahma Ihsan, Mahya Keiza Natania Panjaitan Luri Mekeama M. Rifqi Efendi Maimum Marbun, Sertika Handayani Marhammah, Natasya Putri Muhaimin Muhaimin Mulia, Zulaikha Permata Naurasyifa, Hairania Neldi, Vina Novia Tri Astuti Nugroho, Aulia Hafizhah Nurfadilah Nurfadilah Pondawinata, Marizki Prima Septiana Purba, Eka Novita Br Puspa Dwi Pertiwi Puspa Dwi Pratiwi Putri Aulia, Bilqis Putri Maya Sari Putri, Kresentia R.A. Talitha Nabila Sakhi Rabbani, Haiga Hatthaya Rachmawati, Lilis Ramadani, Arum Kinasih Rion Nofrianda Rizamevia, Fhidila Riziek, Habieb Rizki, Nanda Putri Rohmahdana, Indis Hilwa Sadli, Nurul Kamilah Salsabilah, Indah Sani K, Fathnur Santi Perawati, Santi Saputri, Sindi Savitri, Anita Syamsurizal - - syamsurizal syamsurizal Tri Astuti, Novia Uce Lestari Utami, Diah Tri Utami, Karen Putri Virginia, Yulwilla Wahyu, Delma Aziza Yulia Sari, Ersa Yuliana Yuliana Yuliandani, Yuliandani Yuliawati Zahara