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All Journal CHEMPUBLISH JOURNAL Jurnal Farmasi Sains dan Komunitas PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Ilmu Kefarmasian Indonesia JURNAL FARMASIMED (JFM) SANITAS: Jurnal Teknologi dan Seni Kesehatan Jurnal Peduli Masyarakat MEDIC MEdical Dedication Yayasan Cita Cendikiawan Al Khwarizmi Jurnal Abdimas Kartika Wijayakusuma Journal of Pharmaceutical Care and Sciences Pharmaceutical Sciences and Research (PSR) JOURNAL OF CHEMICAL NATURAL RESOURCES (JCNaR) Jurnal Karya Abdi Masyarakat Sciences of Pharmacy Electronic Journal Scientific of Environmental Health And Diseases Sinteza Jurnal Pengabdian Harapan Ibu (JPHI) Journal of Pharmaceutical and Sciences. Bencoolen Journal of Pharmacy Jurnal Kefarmasian Indonesia Pharmacon: Jurnal Farmasi Indonesia Jurnal Abdimas Kesehatan
Maharini, Indri
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F Formulasi Sediaan Gel Ekstrak Lidah Buaya (Aloe Barbadensis) Dan Daun Sambung Nyawa (Gynura procumbens) Sebagai Alternatif Penyembuhan Luka Dinofitri, Hanifah; Cathelya, Bunga; Idamanda, Rahma; Putri Aulia, Bilqis; Rizamevia, Fhidila; Maharini, Indri; Sani K, Fathnur
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 2 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i2.732

Abstract

Background: Wound care can involve both chemical and natural substances to accelerate the healing process. Aloe vera is known for its wound-healing properties due to the presence of saponins. Similarly, sambung nyawa leaves aid in wound healing because they contain flavonoids. Combining extracts from aloe vera and sambung nyawa is expected to enhance the healing process. Gel formulations are advantageous as they allow for prolonged drug contact with the wound and protect it from external contamination.Objective: This study aims to evaluate the effect of varying concentrations of Carbopol 940 as a gelling agent on the physical properties and stability of the gel, as well as to assess the effectiveness of the gel in promoting the healing of excision wounds.Methodology: The method used in this study is experimental. The gel formulations consist of four formulas with varying concentrations of sambung nyawa leaf extract and Carbopol. Evaluation of the gel's physical properties includes organoleptic tests, homogeneity, spreadability, adhesiveness, pH, viscosity, and stability tests. The excision wound healing test was conducted on mice using six treatment groups. The observed parameter was the percentage of wound healing. Data analysis was performed descriptively and statistically using One-Way ANOVA.Results: The evaluation results of the formulation showed that the developed formula met the standards for physical properties and stability. The best wound-healing effectiveness was observed in treatment group 4, which contained 4% ethanol extract of aloe vera, 5% sambung nyawa leaves, and 2% Carbopol 940.Conclusion: The variation in Carbopol 940 concentration affects the physical properties and stability of the gel formulation. The effectiveness of excision wound healing indicates that higher concentrations of sambung nyawa leaf extract result in better wound-healing efficacy.  
Formulasi dan Evaluasi Sediaan Nano-Gel Minyak Atsiri Daun Nilam (Patchouli oil) Menggunakan HPMC Sebagai Gelling Agent Marhammah, Natasya Putri; Maharini, Indri; Elisma, Elisma; Rabbani, Haiga Hatthaya; Saputri, Sindi; Mulia, Zulaikha Permata; Afriana, Nadila
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 2 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i2.738

Abstract

Background: Acne vulgaris is a chronic inflammation of the pilosebaceous unit characterized by clinical signs of non-inflammatory and inflammatory lesions with varying degrees of inflammation, often caused by bacterial infection. Patchouli plant (Pogostemon cablin Benth) is a notable source of essential oil with antibacterial properties. Enhancing the effectiveness of essential oil as an anti-acne agent can be achieved through the development of a nanogel formulation.Objective: To formulate a nanogel containing patchouli leaf essential oil and evaluate its activity against Propionibacterium acnes.Methods: The formulation of patchouli leaf essential oil nanoemulsion was carried out with varying concentrations of patchouli oil at 1.5%, 2%, and 2.5%. The evaluation of the nanoemulsion included particle size analysis, zeta potential testing, and emulsion type determination. The resulting nanoemulsion was then formulated into a nanogel using HPMC as the gelling agent. The physical evaluation of the nanogel included organoleptic tests, homogeneity tests, viscosity tests, pH measurement, spreadability tests, adhesion tests, stability tests, irritation tests, and antibacterial activity tests. Data analysis was performed descriptively, followed by statistical analysis using One-Way ANOVA with a 95% confidence levelResults: The patchouli leaf essential oil (Patchouli Oil) nanoemulsion with concentrations of 1.5%, 2%, and 2.5% met the criteria for nanoemulsion formulation. The nanogel preparations in F1, F2, and F3 were solid in form, yellowish-white in color, had the characteristic aroma of patchouli leaf essential oil, and were homogeneous, meeting the requirements for gel formulations and stable. Conclusion: The formulation of nanogel containing patchouli leaf essential oil (Patchouli Oil) meets the requirements for a good gel preparation.  
Optimization and Evaluation of Patchouli (Pogostemon cablin Benth.) Leaf Essential Oil Gel using Carbopol and Triethanolamine Marbun, Sertika Handayani; Maimum, Maimum; Maharini, Indri
Jurnal Kefarmasian Indonesia VOLUME 14, NUMBER 2, AUGUST 2024
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The essential oil of Patchouli (Pogostemon cablin Benth.) has antioxidant activity and can be used as an active compound in sunscreen preparations. The index used to describe the effectiveness of sunscreen products is the Sun Protection Factor (SPF). Patchouli oil has never been developed as a sunscreen in gel dosage form. The exploration of patchouli oil is more about testing antioxidant and antibacterial activity. This research aims to optimize the formula and test the SPF (Sun Protection Factor) value of essential oil of Pogostemon cablin gel preparations. Formula optimization using Simplex Lattice Design 13 contained in Design Expert software. The variables optimized in this study were carbopol and triethanolamine concentrations. The responses used in the optimization process are pH, viscosity, adhesion, and spreadability. The optimum formula was evaluated by evaluating the preparation, including organoleptic, homogeneity, pH, viscosity, adhesive power, spreadability, stability, and SPF value test using the UV-Vis spectrophotometric method. The results showed that the optimum formula composition was obtained from a combination of 0.5% carbopol and 0.7% triethanolamine. The optimum formula gel preparation has a yellow appearance and smell typical of patchouli oil, homogeneous, the pH of the preparation is 6.29 ± 0.08, the viscosity of the preparation is 44086.67 ± 1510.69, the adhesive power is 7.62 ± 0.68, the spreadability of 5.42 ± 0.08, stable. The optimum formula gel preparation has an ultra-protection SPF value of 28.87 ± 0.27.
In Vitro Determination of SunProtective Factor (SPF) of Dadap Serep (Erythrina Subumbrans (Haks.) Merr.) Leaf Extract Using Spectrophotometric Method Maharini, Indri
Journal of Chemical Natural Resources Vol. 1 No. 1 (2019): Journal of Chemical Natural Resources
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (621.304 KB) | DOI: 10.32734/jcnar.v1i1.836

Abstract

Dadap serep (Erythrina Subumbrans Haks Merr) contains bioactive compounds of flavonoids, saponins, isoflavones, alkaloids, and lectins. Flavonoid compounds have a sunscreen effect. This studyaimed to determinethe value of Sun Protective Factor (SPF) using spectrophotometry method with variations in the extract concentrations, such as500 ppm,750 ppm, and 1000 ppm.The results showed that the SPF values of each concentration were11.47 ±0.583335, 17.05 ± 0.898838,21.93 ± 0.791557, respectively. In conclusion, the ethanol extract of dadap serep hastheability to become sunscreen in the maximal and ultra category.
Demonstrasi Pembuatan Teh Celup Gaharu sebagai Terapi Preventif Asam Urat di Kelurahan Olak Kemang Perawati, Santi; Pondawinata, Marizki; Kamilah Sadli, Nurul; Neldi, Vina; Maharini, Indri; Tri Astuti, Novia; Elisma, Elisma; Maimum; Naurasyifa, Hairania; Ramadani, Arum Kinasih
Jurnal Pengabdian Harapan Ibu (JPHI) Vol. 7 No. 3 (2025): Jurnal Pengabdian Harapan Ibu (JPHI)
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30644/jphi.v7i3.1120

Abstract

Penyakit asam urat merupakan salah satu masalah kesehatan masyarakat yang prevalensinya terus meningkat, termasuk di Provinsi Jambi. Kondisi ini mendorong perlunya upaya preventif berbasis pemanfaatan bahan alam lokal yang mudah diperoleh dan diterima masyarakat. Daun gaharu (Aquilaria malaccensis) diketahui memiliki kandungan senyawa bioaktif dengan aktivitas antiinflamasi, sehingga berpotensi dikembangkan sebagai terapi preventif terhadap penyakit asam urat. Kegiatan pengabdian masyarakat ini dilaksanakan di Kelurahan Olak Kemang RT.02 Kota Jambi dengan pendekatan partisipatif melalui penyuluhan interaktif dan demonstrasi pembuatan teh celup daun gaharu. Proses kegiatan meliputi tahap identifikasi kebutuhan masyarakat, edukasi kesehatan tentang asam urat, demonstrasi pengolahan teh celup, serta evaluasi peningkatan pengetahuan dan kepuasan peserta. Hasil kegiatan menunjukkan peningkatan rata-rata skor pengetahuan masyarakat dari 64,5 menjadi 92,7 setelah penyuluhan, dengan tingkat kepuasan peserta mencapai 95,4%. Kegiatan ini membuktikan bahwa kombinasi pendekatan edukatif dan praktikal efektif dalam meningkatkan literasi kesehatan dan keterampilan masyarakat dalam memanfaatkan bahan lokal sebagai produk herbal fungsional. Program ini berperan penting dalam pemberdayaan masyarakat dan dapat menjadi model pengembangan ekonomi kreatif berbasis tanaman obat di daerah. Kata kunci : Aquilaria malaccensis, teh celup, asam urat, pengabdian masyarakat, pencegahan penyakit
Gastroprotective effect test of ekor naga leaves extract (Rhaphidophora pinnata (L.f) Schott) on male white rats Sani K, Fathnur; Putri, Kresentia; Elisma, Elisma; Lestari, Uce; Maharini, Indri; Yuliawati, Yuliawati
JURNAL ILMU KEFARMASIAN INDONESIA Vol 23 No 2 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i2.1698

Abstract

Rhaphidophora pinnata leaves are one of the herbal plants that have pharmacological effects. Previous research has shown that ekor naga leaves contain secondary metabolites with tonic pharmacological effects, including the ability to heal cut wounds, as well as antihyperglycemic and antidiabetic properties. This research aims to demonstrate the potential of ekor naga leaf extract as a gastroprotective agent. The extract was evaluated using standard methods, including determination of water content, ash content, phytochemical screening, and compound identification by LC-MS. Gastroprotective testing was carried out by dividing the treatment group into six groups, including the Group 1: normal group, Group 2: negative control (Sodium CMC 0.5%), Group 3: positive control (Sucralfate), Group 4: 125mg/KgBW extract, Group 5: 250 mg/KgBW extract, and Group 6: 500mg/KgBW extract. The results of the observations were in the form of gastric ulcer severity scores and histological images of the gastric organs. Gastroprotective testing revealed significant differences between the treatment groups and the negative control group (p<0.05). The 500 mg/kgBW extract exhibited the most effective gastroprotective effect, with a 42.5% inhibition rate and minimal inflammation observed both macroscopically and microscopically. These results suggest that ethanol extract from ekor naga leaves may serve as an alternative or complementary therapy for gastritis.
DIVERSIFICATION OF HERBAL PRODUCTS BASED ON LOCAL WISDOM AS AN EFFORT TO PREVENT STUNTING FOR THE COMMUNITY OF OLAK KEMANG VILLAGE Kasmadi, Fathnur Sani; Maharini, Indri; Maimum, Maimum; Fitrianingsih, Fitrianingsih; Neldi, Vina; Astuti, Novia Tri; Perawati, Santi; Yuliawati, Yuliawati; Yuliandani, Yuliandani; Nurfadilah, Nurfadilah
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 8 No. 2 (2025): MEDIC. Medical dedication
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Stunting, or chronic malnutrition, remains a significant public health challenge in Indonesia, impacting the cognitive and physical development of children. This community service project aimed to address this issue through a culturally sensitive and sustainable approach in the community of Olak Kemang Village, Jambi. The program focused on diversifying local wisdom-based herbal products to improve nutritional intake among pregnant women, lactating mothers, and children under five. The method involved a three-stage process: (1) socialization and nutritional education about stunting, (2) training on the hygienic processing of local plants rich in micronutrients, such as Moringa (Moringa oleifera) and Katuk leaves (Sauropus androgynus), and (3) a hands-on workshop on creating diversified, child-friendly products like herbal powders, fortified cookies, and puddings. Pre- and post-activity questionnaires demonstrated a significant increase in participants' knowledge and awareness of stunting prevention, from 67,4% to 90,58%. Participants also successfully produced several innovative herbal food products. This initiative highlights that empowering communities by integrating local knowledge with scientific principles is a promising and effective strategy for stunting prevention. Keywords: Stunting, community service, herbal product, nutrition, local wisdom.
Gastroprotective effect test of ekor naga leaves extract (Rhaphidophora pinnata (L.f) Schott) on male white rats Sani K, Fathnur; Putri, Kresentia; Elisma, Elisma; Lestari, Uce; Maharini, Indri; Yuliawati, Yuliawati
JURNAL ILMU KEFARMASIAN INDONESIA Vol. 23 No. 2 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i2.1698

Abstract

Rhaphidophora pinnata leaves are one of the herbal plants that have pharmacological effects. Previous research has shown that ekor naga leaves contain secondary metabolites with tonic pharmacological effects, including the ability to heal cut wounds, as well as antihyperglycemic and antidiabetic properties. This research aims to demonstrate the potential of ekor naga leaf extract as a gastroprotective agent. The extract was evaluated using standard methods, including determination of water content, ash content, phytochemical screening, and compound identification by LC-MS. Gastroprotective testing was carried out by dividing the treatment group into six groups, including the Group 1: normal group, Group 2: negative control (Sodium CMC 0.5%),  Group 3: positive control (Sucralfate), Group 4: 125mg/KgBW extract, Group 5: 250 mg/KgBW extract, and Group 6: 500mg/KgBW extract. The results of the observations were in the form of gastric ulcer severity scores and histological images of the gastric organs. Gastroprotective testing revealed significant differences between the treatment groups and the negative control group (p<0.05). The 500 mg/kgBW extract exhibited the most effective gastroprotective effect, with a 42.5% inhibition rate and minimal inflammation observed both macroscopically and microscopically. These results suggest that ethanol extract from ekor naga leaves may serve as an alternative or complementary therapy for gastritis.
Penentuan Nilai SPF (Sun Protection Factor) Ekstrak Metanol Buah Palem Merah (Crystotachys Renda Blume.) Sebagai Zat Aktif Tabir Surya Syamsurizal, Syamsurizal; Wahyu, Delma Aziza; Maharini, Indri
Jurnal Pelayanan Kefarmasian dan Sains Vol 6 No 1 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v6i1.765

Abstract

Background: Methanol extract from red palm fruit (Crystotachys renda Blume) contains secondary metabolites such as flavonoids, phenols, and tannins that have antioxidant properties. These compounds have the potential to act as sunscreen agents due to their ability to absorb UV-B radiation.Objective: This research aims to determine the Sun Protection Factor (SPF) value of methanol extract from red palm fruit as an active ingredient in sunscreen formulation. Method: This research began with the extraction process of red palm fruit simplicia using the maceration and reflux methods. The measurement of SPF values was conducted in vitro using UV-Vis Spectrophotometry at various concentrations, namely 100, 400, 600, 800, and 1000 ppm. Results: Based on the research findings, the methanol extract of red palm fruit has SPF values of 6.12; 24.43; 29.20; 30.67; and 31.00 at concentrations of 100, 400, 600, 800, and 1000 ppm, respectively. Conclusion: SPF testing shows that at a concentration of 1000 ppm, the methanol extract of red palm fruit has an SPF value of 31.00, which falls into the ultra protection category.      
Health Awareness And Youth Empowerment Program In The Digital Era Fitriyanti; Harahap, Huntari; Humaryanto, Humaryanto; Amalya Nasution, Riska; Nofrianda, Rion; Dwi Puspita, Puspa; Eka Putra, Nofrans; Maharini, Indri; Kalsum, Ummi; Aswin, Budi
Scientific Of Environmental Health and Diseases Vol. 5 No. 2 (2025): Scientific of Environmental Health And Diseases
Publisher : LPPM Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/e-sehad.v5i2.50935

Abstract

Background: The fast-paced digital era presents unique challenges to youth health, including gadget addiction, a lack of clean and healthy living behaviors (PHBS), and the risk of bullying. This community service aimed to enhance health awareness and empower children of Indonesian migrant workers (PMI), parents, and teachers at the PPWNI Klang, Selangor, Malaysia, to foster a healthy and smart generation in the digital age. Method: The research employed a community-based approach, involving initial coordination with the partner and using interactive lectures and direct practice for the training. The core activities included psychoeducation sessions on mitigating gadget addiction, PHBS, and bullying, alongside basic health checks. Evaluation and monitoring were conducted using pre- and post-training questionnaires and behavioral observation. The target participants included PMI children, parents, and teachers. Result: From 48 participants attended the basic health checks, which revealed an average cholesterol level of 205.85, a blood glucose average of 107.23, and a uric acid average of 7.05. The findings indicate a prevalence of hypercholesterolemia among the participants. Conclusion: The program is relevant to the research objectives and is expected to reduce bullying rates, increase PHBS awareness, and promote more controlled use of gadgets. This collaboration with PPWNI Klang demonstrates a commitment to forging a healthy, strong, and smart younger generation capable of navigating the digital era.
Co-Authors ., Elisma Afriana, Nadila Amalya Nasution, Riska Anjaly Rizkya Fazariana Arrahman, Ghery Astuti, Novita Tri Bilia Ayu Septiana Budi Aswin Cathelya, Bunga Cut Mutia Diah Tri Utami Diky Okta Yudha Putra Dinofitri, Hanifah Dominica, Dwi Dwi Puspita, Puspa Efendi, M. Rifki Eka Putra, Nofrans Elisma Elisma Elisma Elisma Elisma Fitri, Zahwa Syuhada Fitrianingsih Fitrianingsih Fitriyanti Hanifah, Risa Harmonyzha, Giga K. Havizur Rahman Humaryanto, Humaryanto Huntari Harahap Idamanda, Rahma Ihsan, Mahya Keiza Natania Panjaitan Luri Mekeama M. Rifqi Efendi Maimum Marbun, Sertika Handayani Marhammah, Natasya Putri Muhaimin Muhaimin Mulia, Zulaikha Permata Naurasyifa, Hairania Neldi, Vina Novia Tri Astuti Nugroho, Aulia Hafizhah Nurfadilah Nurfadilah Pondawinata, Marizki Prima Septiana Purba, Eka Novita Br Puspa Dwi Pertiwi Puspa Dwi Pratiwi Putri Aulia, Bilqis Putri Maya Sari Putri, Chintya Dwiyunia Putri, Kresentia R.A. Talitha Nabila Sakhi Rabbani, Haiga Hatthaya Rachmawati, Lilis Ramadani, Arum Kinasih Rion Nofrianda Rizamevia, Fhidila Riziek, Habieb Rizki, Nanda Putri Rohmahdana, Indis Hilwa Sadli, Nurul Kamilah Salsabilah, Indah Sani K, Fathnur Santi Perawati, Santi Saputri, Sindi Savitri, Anita Syamsurizal - - syamsurizal syamsurizal Tri Astuti, Novia Uce Lestari Utami, Diah Tri Utami, Karen Putri Virginia, Yulwilla Wahyu, Delma Aziza Yulia Sari, Ersa Yuliana Yuliana Yuliandani, Yuliandani Yuliawati Yuliawati Zahara