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All Journal Jurnal Kedokteran Brawijaya Majalah Kedokteran Gigi Indonesia Insisiva Dental Journal : Majalah Kedokteran Gigi Insisiva Dental Journal (Majalah Kedokteran Gigi) Jurnal Kedokteran Gigi Universitas Padjadjaran Padjadjaran Journal of Dentistry Journal of Indonesian Dental Association B-Dent, Jurnal Kedokteran Gigi Universitas Baiturrahmah MDJ (Makassar Dental Journal) Indonesian Journal of Cancer Mandala of Health : A Scientific Journal Cakradonya Dental Journal Medical and Health Journal Journal of Dental and Biosciences
Prihastuti, Christiana Cahyani
Dental Medicine Study Program, Faculty Of Medicine, Jenderal Soedirman University, Purwokerto, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Antibiofilm Activity of Secang Wood (Caesalpinia sappan) Ethanol Extract Against Cariogenic Streptococcus sanguinis FERINA AYU MAHARANI HAIBAR; Christiana Cahyani Prihastuti; Meylida Ichsyani
Journal of Indonesian Dental Association Vol. 8 No. 1 (2025): April
Publisher : Indonesian Dental Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32793/jida.v8i1.1278

Abstract

Streptococcus sanguinis merupakan bakteri pioneer colonizers yang berperan dalam perkembangan biofilm penyebab penyakit karies gigi. Ekstrak etanol kayu secang memiliki potensi antibiofilm yang dapat dikembangkan sebagai terapi alternatif obat kumur untuk pencegahan karies gigi. Penelitian bertujuan untuk mengetahui aktivitas antibiofilm ekstrak etanol kayu secang (Caesalpinia sappan L.) terhadap Streptococcus sanguinis penyebab karies gigi. Aktivitas antibiofilm menggunakan dua uji, uji pertama degradasi biofilm dan uji kedua penghambatan biofilm lanjutan dengan MtP Assay dan pewarnaan kristal violet 1% yang densitas optiknya dibaca pada panjang gelombang 620 nm. Data hasil degradasi penelitian dianalisis menggunakan One-Way ANOVA dan post-hoc LSD. Hasil menunjukkan terdapat perbedaan bermakna seluruh konsentrasi ekstrak dengan kontrol negatif. Konsentrasi efektif degradasi biofilm yaitu konsentrasi 1,56 mg/mL dan konsentrasi efektifpenghambatan pertumbuhan biofilm pada konsentrasi 0,39 mg/mL. Simpulan dari penelitian ini adalah terdapat aktivitas antibiofilm ekstrak etanol kayu secang terhadap Streptococcus sanguinis penyebab karies gigi.
Clinical findings of median rhomboid glossitis in typhoid fever patients: Temuan klinis median rhomboid glossitis pada pasien demam tifoid Erlinda Bella Arista; Luqman Mahadika Cahyono; Thoharoh Laili Nafsih; Christiana Cahyani Prihastuti; Sigit Purnomohadi
Makassar Dental Journal Vol. 14 No. 2 (2025): Volume 14 Issue 2 August 2025
Publisher : Makassar Dental Journal PDGI Makassar

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Abstract

Demam tifoid adalah infeksi akut pada saluran pencernaan akibat Salmonella typhi. Manifestasi oral yang dapat muncul antara lain median rhomboid glossitis. Artikel ini melaporkan kasus MRG pada penderita demam tifoid. Seorang pria berusia 40 tahun dengan keluhan demam, sariawan, mual, muntah, nyeri perut, diare, dan feses kehitaman. Diagnosis demam tifoid dikonfirmasi. Pemeriksaan oral, lesi berupa depapilasi berbentuk jajaran genjang berwarna kemerahan di tengah lidah, yang terasa perih dan dikelilingi lapisan putih yang dapat dikerok. MRG merupakan peradangan pada lidah yang ditandai dengan lesi eritema di median dorsum lidah yang disebabkan oleh infeksi jamur Candida. Temuan lesi oral MRG pada kasus demam tifoid ini diduga dipengaruhi oleh kondisi limfositopenia yang menyebabkan penurunan imunitas pasien sehingga meningkatkan risiko infeksi oportunistik Candida pada rongga mulut. Selain itu, terdapat faktor predisposisi berupa kebiasaan merokok dan oral hygiene yang buruk. Disimpulkan bahwa tatalaksana kasus lesi MRG adalah pemberian informasi dan edukasi pada pasien untuk menjaga kebersihan rongga mulut, menghindari konsumsi makanan dan minuman panas dan pedas yang memperparah keluhan pada lidah.
STRESS LEVEL, SLEEP QUALITY, AND VITAL SIGNS AMONG FIRST-YEAR DENTAL STUDENTS Dwi Nur Indah Sari; Anindita Laksitasari; Angger Waspodo Dias Adrianto; Aditya Priagung Prakosa; Ali Taqwim; Fitri Diah Oktadewi; Christiana Cahyani Prihastuti; Amilia Ramadhani; Fanni Kusuma Djati
Mandala Of Health Vol 19 No 2 (2026): Mandala of Health: A Scientific Journal
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2026.19.2.16357

Abstract

Stress and sleep quality are very important factors in determining health. First-year dental students often experience stress and inadequate sleep due to changes in the campus environment and academic demands. Stress and sleep quality in students can affect academic performance and physical health. The body's vital signs are important indicators that show the body's basic functions and are used to identify health problems. The aim of this study was to determine the relationship between stress levels and sleep quality on the body's vital signs (blood pressure, heart frequency and respiration rate). This research was conducted using a cross sectional method. The sample for this research was first year dental students at Universitas Jenderal Soedirman with a sample size of 50. Data was collected using observation sheets and questionnaires (PSS and PSQI). Data analysis was carried out using Spearman correlation. The results showed that the majority of students had normal vital signs but experienced moderate levels of stress and poor sleep quality. Stress and sleep quality had no relation on blood pressure, pulse frequency or respiration rate (p>0.05), but the majority of individuals who experienced pre-hypertension and tachycardia had moderate levels of stress and poor sleep quality. In addition, there is a significant relationship between stress levels and sleep quality (p<0.05). The conclusion of this study is that stress levels and sleep quality are not related to the body vital signs of first year dental students. However, there is a relationship between stress levels and sleep quality.
Aloe vera Extract Sheet and Egg Albumin (Gallus domesticus) Reduce the Number of Lymphocytes on Gingival Incision Wound A'ziza, Wizni A'dila; Prihastuti, Christiana Cahyani; Rochmawati, Mutia; Rosyada, Alya Ghina; Amanda Putri, Myrna Evana
Jurnal Kedokteran Brawijaya Vol. 32 No. 4 (2023)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2023.032.04.2

Abstract

An incision in the oral cavity is a dental procedure performed in surgical procedures. Suturing is the gold standard in primary wound closure care, however, suturing can cause tissue trauma, scars, and secondary infections. Cyanoacrylate adhesive is one of the alternative tissue glue for wound closure but it has inflammatory risk as suturing, potential toxicity, and accidental adhesion risks. Aloe vera extract sheet based combined with free-range chicken egg albumin is expected to be an alternative method for wound healing of gingival incisions. This study aimed to investigate the effect of administration of Aloe vera extract wound healing sheet (WHS) and free-range chicken egg albumin on the number of lymphocytes in the gingival incision wound as the inflammatory response. Experimental laboratory research with a posttest-only control group design was conducted in 24 male rats (Rattus norvegicus Wistar strain) with an incised gingiva, divided into four groups, namely T1 (50% WHS concentration and chicken egg albumin), T2 (100% WHS concentration and chicken egg albumin), PC (positive control with suturing), NC (negative control without treatment). The treatment was carried out for seven days. The data obtained were analyzed statistically using One-way ANOVA and Post Hoc LSD. The use of Aloe vera extract WHS and free-range chicken egg albumin (T1 and T2) reduced the number of lymphocytes compared to control groups (PC and NC; p<0.05). WHS and chicken egg albumin can shorten the inflammatory process in wound healing which is characterized by lower lymphocyte counts compared to the control groups.
Co-Authors A Haris Budi Widodo A'ziza, Wizni A'dila A. Haris Budi Widodo Aditya Priagung Prakosa Affan Wirutomo Aldina Gusri Ali Taqwim Ali Taqwim Alya Ghina Rosyada Amanda Putri, Myrna Evana Amilia Ramadhani Amilia Ramadhani Andini, Restian Febi Angger Waspodo Dias Adrianto Anindita Laksitasari Anindita Laksitasari Anung Saptiwulan Ario Ditto Primandaru Aris Aji Kurniawan Arista, Erlinda Bella Arundito Widikusumo Ayustia, Nadya Cahyono, Luqman Mahadika Daniel Joko Wahyono De Silva, Ghea Dewanti Intan Pamungkasari Diah Krisnansari Diah Krisnansari Dody Novrial, Dody Dwi Nur Indah Sari Dwi Nur Indah Sari Dwi Nur Indah Sari, Dwi Nur Indah Eka Prasasti Nur Rachmani Erlinda Bella Arista Fanni Kusuma Djati Fanni Kusuma Djati FERINA AYU MAHARANI HAIBAR Fitranto Arjadi Fitranto Arjadi Fitri Diah Oktadewi Fitri Diah Oktadewi Ghani, Muhammad Hisyam Gusri, Aldina HAIBAR, FERINA AYU MAHARANI Haidy Lailatun Nabila Haris Budi Widodo Haris Budi Widodo Haris Budi Widodo Helmi Hirawan Irene Putri Jayanti Jayanti, Irene Putri Kusuma, Maulidina Raihan Laksitasari, Anindita Luqman Mahadika Cahyono Mahindra Awwaludin Romdlon Mahindra Awwaludin Romdlon Maziyyah, Faiz Meylida Ichsyani Muhammad Hisyam Ghani Mutia Rochmawati Nabila Prandita Bagasworo Nabila, Haidy Lailatun Nadiyah, Aisyah Nafsih, Thoharoh Laili Naim, Cantika Nadrotan Pamungkasari, Dewanti Intan Purnomohadi, Sigit Putri, Annisa Liontyn Adies Putri, Myrna Evana Amanda Rachmad Aji Saksana Rachmad Aji Saksana Rakhmawati Rakhmawati Restian Febi Andini Rinawati Satrio Rosyada, Alya Ghina Salisa, Ziyada Satrio, Rinawati Setiawati Setiawati Sigit Purnomohadi Solihin, Bella Ayuni Adhianti Tanjung, Nurul Hasanah Thoharoh Laili Nafsih Tirta Wardana Tuti Sri Suhesti Widodo, A Haris Budi