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Characteristics of Osteoarthritis Patients at PKU Bantul Hospital in 2024 Prisila, Elvina; Wijayanti Sukirto, Novi; Ilham Rahmatullah, Andika; Pirman Abdul Aziz, Adinda; Arrafi Pratama, Rheycado; Chairunnisa Ramadhani, Salsabila; Yuniasih, Dewi
Ahmad Dahlan Medical Journal Vol. 6 No. 1 (2025): May 2025
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/admj.v6i1.13098

Abstract

Osteoarthritis (OA) is a degenerative joint disorder that commonly affects the elderly population, primarily resulting from the aging process and prolonged mechanical stress on articular cartilage. The risk of deceloping OA significantly increases between the ages of 30 and 65, with individuals over the age of 65 facing a tenfold higher risk. Common clinical manifestations include joint pain, stiffness, swelling, and reduced mobility, which can severely impact quality of life. This study aims to provide a comprehensive overview of the demographic and clinical characteristics of OA patients treated at PKU Bantul Hospital between January and December 2024. A cross-sectional design was employed, utilizing secondary data extracted from hospital’s medical records. A total of 579 OA patients were identified, with a predominant female population (419 individals, 41,1%). The vast majority received outpatient care (540 individuals, 93,3%). Radiological examinations were conducted in 462 patients (80%), with the knee joint being the most commonly affected site (369 cases, 64%). These findings highlight the high burden of OA among elderly females and underscore the importance of early diagnosis and effective management strategies, particularly for knee involvement, to prevent disease progression and improve patient outcomes.
The Importance of Oral Health Education for Kindergarten Students in Rural Areas Widyatama, Rendra; Ananda, Dhiaksa Adhi; Ananda, Vidya; Yuniasih, Dewi
Jurnal Pengabdian kepada Masyarakat (Indonesian Journal of Community Engagement) Vol 11, No 3 (2025): September
Publisher : Direktorat Pengabdian kepada Masyarakat Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpkm.104916

Abstract

Oral health is essential for overall human well-being. Everyone, regardless of age—whether young or old—must maintain good dental hygiene, including kindergarten children in rural areas. Unfortunately, knowledge of oral health and tooth-brushing skills among kindergarten students in these regions remains inadequate. To improve their understanding of dental health and proper brushing techniques, effective educational methods are required. In response to this issue, a community service team implemented a multi-method approach targeting two groups: primary and secondary beneficiaries. The primary group consisted of kindergarten students, who were engaged through interactive counseling, demonstrations, question-and-answer sessions, singing, games, rewards, and practical tooth-brushing exercises. Meanwhile, for the secondary group—teachers and parents—the team utilized persuasive communication via WhatsApp messages, providing oral health education and encouraging parents to consistently remind their children to practice proper dental hygiene daily. Based on the program evaluation, the multi-method approach was proven effective in enhancing both the knowledge and skills of kindergarten children in maintaining oral health. Furthermore, it contributed to creating an environment that fosters healthy behavior among children. Therefore, the team believes that dental health practitioners and educators can adopt similar methods to achieve optimal outcomes in promoting oral health awareness.
COMPARISON OF INTRAPERITONEAL AND INTRADUCTAL ROUTES IN THE GROWTH OF N-METHYL-N-NITROSOUREA-INDUCED BREAST CANCER IN SPRAGUE DAWLEY RATS: A SYSTEMATIC REVIEW 2014–2024 Prameswari, Adilla Soraya; Sompokan, Ruendhita Azzahra Sari; Annisa, Annisa; Putri, Rachma Greta Perdana; Yuniasih, Dewi; Danian, Muhamad; Tianotak, Muhammad Tri Yoga
Folia Medica Indonesiana Vol. 61, No. 2
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Breast cancer is one of the[-6pc]AU: Please provide affiliations for your paper. leading causes of death for women worldwide, characterized by malignant tumors in the mammary epithelium. Breast cancer modelling using Sprague Dawley animals induced by N-Methyl-N-Nitrosourea (MNU) compounds is commonly used through various administration routes. The intraperitoneal route is the conventional route and the intraductal route is a new route capable of directly targeting the mammary ducts. Both routes affect the speed and characteristics of breast cancer cells in experimental animals. This systematic review using PubMed and Scopus databases from 2014-2024 aims to compare the effects of intraperitoneal and intraductal administration routes on breast cancer induction and the similarities in histopathological characteristics and biomarkers with human breast cancer cells. Of the 324 articles, 15 met the inclusion criteria showing that the intraductal route induces tumors faster (6–8 weeks) with Ductal Carcinoma In Situ (DCIS) type, ER+/PgR+ expression, and low Ki-67 index, resembling the luminal A subtype. The intraperitoneal route requires 8–12 weeks, producing multiple tumors with a high Ki-67 index, resembling luminal B. Administration of additional substances such as PF4, white tea, and physical activity are anti-tumorigenic, while radiation and a high-fat diet are pro-tumorigenic. Therefore, the intraductal route can be used as the main choice in selecting the route of administration of MNU induction.
Co-Authors Adnan Alfiani Laariya, Tira Ananda, Dhiaksa Adhi Ananda, Vidya Annisa Annisa Annisa, Ika Nur Ari Mulyani, Dewi Ariandi, Tifanny Rizka Ariani, Rizka Ario Tejosukmono Aristiani, Windy Arrafi Pratama, Rheycado Asmadi Alsa Assyifa Oktavia Wiraningtyas Astiti, Chairunnisa Awisarita , Wiwara Awisarita, Wiwara Budi Rahayu, Ana Chairunnisa Ramadhani, Salsabila Danian, Muhamad Dewantari, Aulia Nissa Dewantari, Aulia Yasmin Elistiana, Dinda Ian Farihan, Wildan Fandi Fauziyah Rahmawati, Nurul Helfi Agustin Heriyanto, Mochammad Junaidy Hikmawan Yuliarto Benni Sambada, Taufiek Husna, Maratul Hutari, Andri Ihsana, Nuni Ilham Rahmatullah, Andika Iman Permana, Iman Kurniawan, Nurcholid Umam Laariya, Tira Alfiani Laksana, Zen Adi Mansur, Auliya Azisah Mawardi, Fitriana Miftahulhaq murdiyanto, joko Nafiuzzaqi, Muhammad Faris Nuraga, Hega Fitri Nurcholid Umam, Nurcholid Nurulita, Febrianti Putri Pamungkas, Ade Tia Bintang Pamungkasih, Wahyu Perdana Putri, Rachma Greta Pirman Abdul Aziz, Adinda Prameswari, Adilla Soraya Prisila, Elvina Prisilla, Elvina Puspa Sari , Ade Putri Nurulita, Febrianti Putri, Rachma Greta Perdana Putri, Rachmagreta Perdana Rahayu, Ana Budi Rahma, Shafa Sabilla Rahmawati, Nurul Fauziyah Rendra Widyatama Rokhmah, Budi Nur Rokhmayanti, Rokhmayanti Rossi Desvita, Widea Sabirin, Rahmaningsih Mara Salsabila, Katrina Rizky Salsabila, Shafa Zahra Selohandono, Andrianto Septianingsih, Lia Shalsabila, Dhea Sholikhah, Amanatus Sistharani, Naila Siti Fatimah Sompokan, Ruendhita Azzahra Sari Suhendra Sukirto, Novi Sukirto, Novi Wijayanti Sumarno, Andhira Setya Yudha Suprabandari, Suprabandari Susilawati, Okti Tianotak, Muhammad Tri Yoga Triantoro Safaria Ulfa, MH Muflihatul Umam Kurniawan, Nurcholid Widea Rossi Desvita Wijayanti Sukirto, Novi Wira Okta Viana