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All Journal Jurnal Kesehatan Andalas Berkala Ilmu Kesehatan Kulit dan Kelamin Biomedical Journal of Indonesia Jurnal Review Pendidikan dan Pengajaran (JRPP) Health and Medical Journal JURNAL PENELITIAN PERAWAT PROFESIONAL Indonesian Journal of Global Health research Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks JOURNAL LA MEDIHEALTICO Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Indonesia Sosial Sains Eduvest - Journal of Universal Studies Media Dermato-Venereologica Indonesiana Detector: Jurnal Inovasi Riset Ilmu Kesehatan Journal of General Procedural Dermatology and Venereology Indonesia Jurnal Riset Ilmiah Prosiding Seminar Nasional Unimus Seroja Husada: Jurnal Kesehatan Masyarakat Proceeding International Conference Of Innovation Science, Technology, Education, Children And Health Proceeding International Conference Of Innovation Science, Technology, Education, Children And Health JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia
Gardenia Akhyar
Andalas University
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Comparison of quality of life, anxiety, and depression levels based on acne vulgaris severity Husna, Annisaul; Yenny, Satya Wydya; Desmawati, Desmawati; Akhyar, Gardenia; Masrul, Masrul; Yulistini, Yulistini
Journal of General - Procedural Dermatology and Venereology Indonesia Vol. 8, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Acne vulgaris is a chronic inflammation of the pilosebaceous unit. Although acne vulgaris is not fatal, it can cause psychological effects. This study aimed to compare the quality of life, anxiety, and depression levels based on the severity of acne vulgaris among medical students at Andalas University. Methods: This was an observational-analytic study with a cross-sectional design. It was conducted from May to June 2023. The population included the third-grade students of the Medical Study Program of the Faculty of Medicine, Andalas University, who had acne vulgaris. The respondents were 70 people, recruited with consecutive sampling techniques. This research used Lehmann classifications to classify acne severity, the Cardiff Acne Disability Index (CADI) to assess quality of life, and the Depression Anxiety Stress Scale (DASS-21) to assess anxiety and depression. The statistical analysis used the Kolmogorov-Smirnov test. Results: Most female respondents, aged 20 years old, experienced mild acne vulgaris (84.3%). Additionally, the respondents predominantly had mild quality of life disorders (80%), normal anxiety level (32.9%), and normal depression level (52.9%). The Kolmogorov-Smirnov test found no relationship between the severity of acne vulgaris with quality of life (p = 0.076), anxiety level (p = 0.623), and depression level (p = 0.751). Conclusion: The results showed that most respondents had mild acne vulgaris, mild impairment in quality of life, normal anxiety level, and normal depression level. Statistical tests revealed no significant association between the severity of acne vulgaris and these variables.
Factors Associated with the Incidence of Hand Dermatitis Among Car and Motorcycle Wash Workers in East Padang District Shafiqah Zawira; Gardenia Akhyar; Selfi Renita Rusjdi; Ennesta Asri; Biomechy Oktomalio Putri; Yustini Alioes
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 12 No 2 (2025): JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol. 12.2 (2025)
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.v12i2.997

Abstract

Introduction: Hand dermatitis is a common occupational skin disorder caused by repeated exposure to irritants or allergens. Workers in car and motorcycle wash services are particularly vulnerable due to their frequent contact with detergents and cleaning agents, as well as prolonged exposure to wet work. This study aimed to identify factors associated with hand dermatitis among workers in East Padang District. Methods: A quantitative analytical observational study with a cross-sectional design was conducted among 32 workers selected through simple random sampling. Data were collected through direct interviews using a validated questionnaire. Univariate and bivariate analyses were performed, with chi-square tests used to evaluate associations between hand dermatitis and variables including working period, duration of contact, age, atopic history, personal hygiene, and use of personal protective equipment (PPE). Results: Hand dermatitis was identified in 65.6% of respondents. Bivariate analysis revealed significant associations between duration of contact (p = 0.020), personal hygiene (p = 0.027), and PPE use (p < 0.000) and the incidence of hand dermatitis. No significant associations were found for working period (p = 0.798), age (p = 0.211), or atopic history (p = 0.637). Discussion: Prolonged exposure to irritants, inadequate hygiene practices, and non-use of PPE likely heighten skin barrier disruption, predisposing workers to dermatitis. Conversely, factors such as age and atopic predisposition may play a minor role in this occupational group. Conclusion: Duration of contact, personal hygiene, and the use of PPE are significantly associated with hand dermatitis among car and motorcycle wash workers. In contrast, working period, age, and atopic history show no meaningful relationship. Strengthening preventive practices, remarkably consistent PPE use, is essential.
Community Empowerment of Nagari Salimpek in Developing a Herbal Cosmetic Village Based on Family Medicinal Plants (TOGA) Yenny, Satya Wydya; Gustia, Rina; Rahmatini; Usman, Elly; Asri, Ennesta; Akhyar, Gardenia; Ariani, Tutty; Sari, Mutia; Sari, Indah Indria; Yossy, Vesri; Julia, Dwi Sabtika; Ashar, Miranda; Taria, Sari Almira
Warta Pengabdian Andalas Vol 33 No 1 (2026)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.33.1.67-74.2026

Abstract

Nagari Salimpek in Alahan Panjang, West Sumatra, has a potential for wellness tourism due to its rich biodiversity, especially medicinal and cosmetic plants. However, community awareness in managing Family Medicinal Gardens (TOGA) remain limited, with only three of twenty household groups actively cultivating herbal plants. This condition emphasizes the need for community empowerment to optimize health and economic benefits from local resources. This community service program aimed to enhance local capacity in cultivating and processing TOGA as the basis for developing a Herbal Cosmetic Village. The programme began on 19 July 2025 and was evaluated over six months. Activities included educational sessions on TOGA utilization, training on herbal and cosmetic plant processing, distribution and planting of herbal seeds, and the signing of a Memorandum of Agreement (MoA) with local stakeholders. A pre-test and post-test evaluation involving 31 participants showed significant improvement in knowledge, with understanding of the “herbal center village” concept rising from 29% to 55% and awareness of Nagari Salimpek’s potential increasing from 32% to 77%. Overall, participants gained broader insights into the role of TOGA in health, cosmetics, and economic development. These results highlight the importance of continued education, mentorship, and government support to establish Nagari Salimpek as a model Herbal Cosmetic Village for wellness tourism.
Profil Pasien Katarak Kongenital di Poli Mata RSUP Dr. M. Djamil Padang periode 2020-2022 Kusumayanti, Ratna Dwi; Sayuti, Kemala; Akhyar, Gardenia; Hendriati, Hendriati; Afdal, Afdal; Anggraini, Fika Tri
Jurnal Ilmu Kesehatan Indonesia Vol. 7 No. 1 (2026): Maret 2026
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v7i1.1325

Abstract

Latar Belakang: Salah satu penyebab utama kebutaan pada bayi baru lahir dan anak-anak adalah katarak kongenital. Kekeruhan lensa sejak lahir ini dapat menghambat perkembangan visual dan berisiko menimbulkan ambliopia permanen bila tidak ditangani dini. Variasi etiologinya luas sehingga deteksi dini dan penatalaksanaan yang tepat menjadi sangat penting. Operasi yang dilakukan pada pasien katarak kongenital adalah Extra Capsular Cataract Extraction (ECCE) tanpa atau dengan pemasangan Intraocular Lens (IOL). Namun, pemasangan IOL jarang dilakukan pada anak di bawah usia 2 tahun. Objektif: Tujuan penelitian untuk mengetahui profil pasien katarak kongenital di Poli Mata RSUP Dr. M. Djamil Padang. Metode: Penelitian ini merupakan penelitian deskriptif retrospektif dengan teknik pengambilan sampel yaitu total sampling. Data rekam medis diperoleh dari 29 pasien yang terdiagnosis katarak kongenital pada periode 2020-2022 di Poli Mata RSUP Dr. M. Djamil Padang. Seluruh variabel dilakukan analisis univariat. Hasil: Hasil dari penelitian ini didapatkan kelompok usia katarak kongenital terbanyak 12-59 bulan (37,9%), sebagian besar berjenis kelamin laki-laki (62,1%) dan merupakan penderita katarak bilateral (72,4%). Infeksi intrauterin merupakan penyebab yang banyak ditemukan (44,8%), tetapi sebagian besar idiopatik (48,3%). Sebagian besar pasien katarak kongenital dilakukan prosedur ECCE tanpa IOL (61,5%). Kesimpulan:  Katarak kongenital sering terjadi pada usia 12-59 bulan, laki-laki, dan bersifat bilateral. Faktor idiopatik merupakan penyebab utama terjadinya katarak kongenital. Sebagian besar pasien ditatalaksana ECCE tanpa pemasangan IOL karena sebagian besar pasien berusia di bawah 2 tahun.
PERKEMBANGAN TERKINI TEKNOLOGI SISTEM PENGHANTARAN TERAPI TOPIKAL PADA PSORIASIS Agung Bima Putera; Gardenia Akhyar
Media Dermato-Venereologica Indonesiana Vol 53 No 2 (2026): Media Dermato Venereologica Indonesiana
Publisher : Perhimpunan Dokter Spesialis Kulit dan Kelamin Indonesia (PERDOSKI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33820/mdvi.v53i2.537

Abstract

   Psoriasis vulgaris adalah penyakit peradangan kulit kronis dengan gejala klinis berupa lesi kulit bersisik dan eritema, yang disertai gatal dan memengaruhi kualitas hidup pasien. Terapi topikal merupakan terapi lini pertama dalam pengelolaan psoriasis vulgaris, tetapi efektivitasnya sering kali terbatas akibat sulitnya penetrasi obat ke lapisan kulit yang lebih dalam dan ketahanan terhadap degradasi obat di lingkungan epidermis yang terinflamasi. Perkembangan sistem penghantaran terapi topikal yang lebih efisien dan spesifik menjadi area penelitian yang sangat penting dalam bidang dermatologi saat ini. Berbagai inovasi dalam sistem penghantaran obat topikal untuk psoriasis vulgaris telah dieksplorasi untuk meningkatkan efikasi, mengurangi iritasi kulit, dan meminimalkan efek samping. Teknologi penghantaran dengan microneedle, nanopartikel, nanofiber, dan hidrogel telah terbukti mampu meningkatkan penetrasi obat, memodulasi pelepasan obat secara bertahap, serta mengurangi ketidaknyamanan pasien. Formulasi topikal yang dirancang dengan sistem penghantaran terkendali ini dapat memberikan pelepasan obat yang lebih efektif dan jangka panjang, serta mengurangi frekuensi aplikasi yang diperlukan. Dengan adanya penelitian lebih lanjut dalam inovasi formulasi, terapi topikal psoriasis di masa depan diharapkan dapat meningkatkan hasil terapeutik dan kualitas hidup pasien secara signifikan. 
The Role of Janus Kinase Inhibitors in Dermatology Rika Desviorita; Gardenia Akhyar
Eduvest - Journal of Universal Studies Vol. 6 No. 2 (2026): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v6i2.52322

Abstract

Janus kinase (JAK) is an intracellular protein of non-receptor tyrosine kinase that functions in cellular regulation and cytokine signaling, thereby producing inflammation. Inhibition of JAK with small molecules that modulate cytokines by blocking the release of Adenosine Triphosphate (ATP) for JAK phosphorylation can prevent inflammation. These molecules are known as Janus Kinase Inhibitors (JAKi). Several related studies have demonstrated that JAKi can be used in the treatment of autoimmune and neoplastic conditions both topically and systemically. Currently, JAKi has been utilized in dermatology and has obtained approval from the Food and Drug Administration (FDA), primarily for treating Atopic Dermatitis (AD), Alopecia Areata (AA), psoriasis, and vitiligo. This review examines the molecular mechanisms of JAK/STAT pathway dysregulation in inflammatory skin diseases, evaluates the efficacy and safety profiles of both topical and systemic JAKi formulations across multiple dermatological conditions, and compares their therapeutic effectiveness against conventional immunosuppressants and biologic agents. The findings indicate that JAKi demonstrates superior rapid onset of action, multi-target cytokine suppression, and favorable safety profiles in short-to-medium term use, positioning them as innovative therapeutic alternatives for patients with treatment-refractory inflammatory skin diseases.
HUBUNGAN PAPARAN TUNGAU DEBU RUMAH DENGAN URTIKARIA DAN/ATAU ANGIOEDEMA PADA ANAK DI PANTI ASUHAN KECAMATAN PAUH KOTA PADANG Muhammad Rafif Sulthan Habibi; Selfi Renita Rusjdi; Gardenia Akhyar; Adrial Adrial; Qaira Anum; Dwitya Elvira
SINERGI : Jurnal Riset Ilmiah Vol. 3 No. 7 (2026): SINERGI : Jurnal Riset Ilmiah, Juli 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v3i7.2793

Abstract

Urticaria is a skin condition characterized by wheals, which may be accompanied by itching, a burning sensation, or pain, and can occur together with angioedema. House dust mites (HDM) are one of the main aeroallergens capable of triggering IgE-mediated allergic skin reactions. Children living in crowded environments, such as orphanages, are at high risk of HDM exposure. This study aimed to determine the relationship between house dust mite exposure and the occurrence of urticaria and/or angioedema in children at an orphanage in Pauh District, Padang City. This was an observational analytical study with a cross-sectional approach, conducted at an orphanage in Pauh District, Padang City, and in the Parasitology Laboratory of the Faculty of Medicine, Andalas University, from March to October 2025. The sampling technique used was total sampling. Bed dust was collected using a vacuum cleaner, and interviews were conducted using an adapted UAS and ISAAC questionnaire. Chi-square was used to analyze the relationship between the two variables. The results of this study showed that all dust samples (100%) were positive for house dust mites, and identification revealed that the most common species found was Dermatophagoides sp. (57.14%), followed by Acarus sp. (32.14%), Cheyletus sp. (25%), Carpoglyphus sp. (17.86%), Glycyphagus sp. (14.29%), Thyrophagus sp. (14.29%), and Blomia tropicalis (7.14%). The average density of house dust mites was 72.85 mites/gram of dust. The prevalence of urticaria and/or angioedema in children was 25.6%. This study found no significant association between house dust mite density and the occurrence of urticaria and/or angioedema (p = 0.263). The conclusion of this study is that factors such as individual predisposition, environmental conditions, and immune sensitization status are likely to contribute to the development of urticaria and/or angioedema.
The Relationship between Diabetes Mellitus and Hypertension with Pemphigus Vulgaris in Pemphigus Vulgaris Patients Muhamad Firdaus; Gardenia Akhyar; Amel Yanis
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.6207

Abstract

Pemphigus vulgaris (PV) is a chronic autoimmune skin disease that manifests as loose vesicles and bullae that affect the mucosa and skin. The first-line therapy for PV is systemic corticosteroids. Although corticosteroid therapy is effective as treatment for pemphigus vulgaris, long-term use of corticosteroids causes various complications such as diabetes mellitus and hypertension. Objectives to examine the relationship of pemphigus vulgaris with diabetes mellitus and hypertension. This study is a retrospective analytic study with a cross sectional approach with a sample size of sixteen people with pemphigus vulgaris. This research was conducted in March – August 2022 at Dr. M. Djamil Hospital in Padang. Relationship analysis is performed using Fisher's exact test by comparing the incidence of diabetes mellitus and hypertension in patients with pemphigus vulgaris with patients with other autoimmune bullous diseases. There is no significant relationship between pemphigus vulgaris and diabetes mellitus (p = 0.133) and hypertension (p = 0.253). The profile of patients with pemphigus vulgaris is also obtained: the annual incidence of PV is 3.2 cases/year; the majority of PV patients are women, with a female to male ratio of 1:0,78; the majority of PV patients are in the 40-60 year age group; the occupation of the most PV patients is housewives; and the majority of clinical manifestations of patients with PV are found on the skin and mucous membranes. There is no significant relationship between pemphigus vulgaris with diabetes mellitus and hypertension.
Profil Pasien Dermatitis Atopik di Poliklinik Kulit dan Kelamin RSUP dr. M. Djamil Padang Periode 2018-2023 Alifya Rafifah Tarwandi; Rina Gustia; Julizar; Gardenia Akhyar; Dwitya Elvira; Yusticia Katar
Jurnal Ilmu Kesehatan Indonesia Vol. 7 No. 2 (2026): Juni 2026
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v7i2.1472

Abstract

AbstrakLatar belakang: Dermatitis atopik merupakan peradangan kulit kronis yang memengaruhi kualitas hidup penderita. Sejauh ini, penelitian terkait profil dermatitis atopik di berbagai kelompok usia telah dilakukan di beberapa wilayah Indonesia, namun belum ada di kota Padang.Objektif: Mengidentifikasi profil pasien dermatitis atopik di Poliklinik Kulit dan Kelamin RSUP Dr. M. Djamil Padang periode Januari 2018 - Desember 2023.Metode: Penelitian ini bersifat deskriptif observasional. Sampel diambil dengan teknik total sampling, menggunakan 31 rekam medik pasien dermatitis atopik di RSUP Dr. M. Djamil Padang periode Januari 2018 hingga Desember 2023.Hasil: Penelitian menunjukkan bahwa dermatitis atopik paling sering terjadi pada anak-anak (45,2%), dengan prevalensi lebih tinggi pada perempuan (51,6%) dan sebagian besar pasien tinggal di perkotaan (74,2%). Mayoritas pasien adalah pelajar (51,6%). Sebanyak (38,7%) pasien memiliki riwayat atopi, dengan rinitis alergi sebagai yang paling umum (41,7%), dan (67,7%) pasien memiliki riwayat atopi dalam keluarga. Gejala utama berupa gatal dan bintik merah pada kulit (64,5%). Lesi sering ditemukan di wajah pada infantil (83,3%), di tungkai pada anak-anak (85,7%), dan di tungkai serta lengan pada orang dewasa (63,6%), dengan sebagian besar kasus memiliki derajat keparahan ringan berdasarkan skor SCORAD (61,3%). Pengobatan yang paling sering digunakan adalah antihistamin dan kortikosteroid topikal (27,9%).Kesimpulan: Dermatitis atopik banyak terjadi pada anak, terutama perempuan di perkotaan. Gejala utama adalah gatal dengan bintik merah, dan kebanyakan kasus ringan. Pengobatan yang sering digunakan adalah antihistamin dan kortikosteroid topikal.Kata kunci: dermatitis atopik, profil, riwayat atopi, SCORAD
Co-Authors Abdiana Abdiana, Abdiana Adissa Benanda Adrial Adrial Adriswan, Saffana Thara Qalbi Afdal Afdal, Afdal Afdhila , Irhamni Nur Afriani, Nita Agung Bima Putera Agustin Vira Agustin Vira ALADIN ALADIN Alifya Rafifah Tarwandi Alimuddin Tofrizal Alvarino Alvarino Amel Yanis Amelin, Fitrisia Andani Eka Putra Andrini Ariesti Andrini Ariesti Anum, Qaira Ariani , Novita Ariani, Tutty Ashal, Taufik Ashar, Miranda Asri, Ennesta Astria Rima Rara Yuswir Astria Rima Rara Yuswir Benanda, Adissa Cimi Ilmiawati, Cimi Dedy Kurnia Desmawati Desmawati Dwi Sabtika Julia Dwitya Elvira Dwitya Elvira Endrinaldi Ennesta Asri Ennesta Asri Erlina Rustam Fathiyyatul Khaira, Fathiyyatul Fauzana Nazifah Fika Tri Anggraini Fikri Fadhil Fortuna, Fory Gusti Revilla Hendriati, Hendriati Husna, Annisa Tamara Husna, Annisaul I. Izrul Ida Rahmah Burhan Indah Indria Sari Indah Indria Sari Irdawati Izrul Irdawaty Izrul Irhamni Nur Afdhila Izrul, Irdawaty Jefrizal Wirman Julita Julita Julita Julita Julizar Julizar Julizar Julizar Kemala Sayuti Kurnia, Dedy Kusumayanti, Ratna Dwi Lestari, Rahmi M. Ashar Maimi, Afaf Aqil Mardhiati Mardhiati Masrul Djalal Meligasari L Gaya Muhamad Firdaus Muhammad Rafif Sulthan Habibi Mutia Sari Nagara, Adianto Jaya Nailatul Fadhila Netti Suharti, Netti Nofita , Eka Novian Novian Novian Novian Nur, Fauziah Nurul Izzah Putri, Biomechy Oktomalio Rahma Ledika Veroci Rahmatini . Raveinal Rendra Darma Satria Rendra Darma Satria Rika Desviorita Rika Desviorita Rika Desviorita Rina Gustia Riri Prima Yolanda Rizki Dwayana Rizki Dwayana Rizkia Chairani Asri Salwa Azzahra Sari, Indah Indria sari, Mutia Satya Wydya Yenny Selfi Renita Rusjdi Shafiqah Zawira Syamel Muhammad Taria, Sari Almira Tiffany, Begum Tofrizal Tutty Ariani Tutty Ariani Vesri Yossy Vitresia, Havriza Yenni Raflis Yola Fadilla Yosse Rizal Yossy, Vesri Yulistini, Yulistini Yusticia Katar Yustini Alioes Zafira, Qory Zurayya Fadila