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Uji Daya Hambat Filtrat Lactobacillus gasseri Terhadap Pertumbuhan Staphylococcus aureus yang Diisolasi dari Genitalia Wanita Husna, Annisa Tamara; Suharti, Netti; Akhyar, Gardenia; Putra, Andani Eka; Muhammad, Syamel; Ilmiawati, Cimi
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 4 (2024): Desember 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i4.1329

Latar Belakang: Lactobacillus gasseri merupakan salah satu jenis bakteri terbanyak ditemukan pada vagina wanita yang dapat menghasilkan bakteriosin sebagai senyawa antibakteri. Bakteriosin dijadikan alternatif melawan bakteri yang resisten terhadap antibiotik, salah satunya Staphylococcus aureus. Selain itu, Staphylococcus aureus merupakan salah satu penyebab vaginitis aerobik yang diteliti dapat membahayakan kehamilan hingga persalinan. Objektif: Tujuan penelitian ini adalah mengetahui kadar hambat minimal (KHM) dan kadar bunuh minimal (KBM) sebagai indikator untuk melihat kemampuan filtrat bakteriosin Lactobacillus gasseri dalam menghambat pertumbuhan Staphylococcus aureus. Metode: Penelitian ini dilakukan pada bulan Mei-November 2023 di Laboratorium Mikrobiologi Fakultas Kedokteran Universitas Andalas dan Laboratorium Pusat Diagnostik dan Riset Penyakit Infeksi Fakultas Kedokteran Unand. Sampel penelitian ini adalah Staphylococcus aureus yang diperoleh dari swab vagina yang dikultur di Laboratorium Mikrobiologi Fakultas Kedokteran Universitas Andalas. Penelitian dilakukan dengan teknik dilusi dan Real Time PCR dengan desain penelitian rancangan acak lengkap. Hasil: Nilai KHM dari filtrat bakteriosin Lactobacillus gasseri terhadap Staphylococcus aureus diperoleh pada konsentrasi >20% dan <40%, sedangkan nilai kadar bunuh minimal (KBM) diperoleh pada konsentrasi 40%. Kesimpulan: Filtrat bakteriosin Lactobacillus gasseri memiliki efek bakteriostatik dan bakterisidal terhadap pertumbuhan Staphylococcus aureus yang dipengaruhi oleh konsentrasi dari filtrat bakteriosin Lactobacillus gasseri.

Performing Ocular Examinations as A Component of Self-Care For Individuals with Leprosy with The Aim of Eradicating Social Stigma and Prejudice Hendriati Hendriati; Tutty Ariani; Havriza Vitresia; Kemala Sayuti; Andrini Ariesti; Julita Julita; Qaira Anum; Satya Wydya Yenny; Rina Gustia; Gardenia Akhyar; Ennesta Asri; Indah Indria Sari; Astria Rima Rara Yuswir; Novian Novian; Rizki Dwayana; Agustin Vira; Rika Desviorita; Rendra Darma Satria
Warta Pengabdian Andalas Vol 31 No 3 (2024)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.31.3.537-546.2024

Leprosy is still a health problem in several countries, including Indonesia. Disability due to leprosy is a health threat for sufferers and causes quality-of-life problems that can disrupt the productivity of leprosy patients. Ocular involvement in leprosy is joint, but little data has been reported. Apart from multi-drug treatment (MDT), leprosy sufferers must also be able to carry out continuous self-care to prevent further disability. This is a collaborative activity between the Department of Ophthalmology and Dermatology Venereology of the Faculty of Medicine, the University of Andalas in Puskesmas Pauh Kamba district of Padang Pariaman. This is an advocacy activity on self-care (3M: Seeing, Examining, and Protecting) and eye examination. The activity was followed by interactive discussions and continued with a direct examination for skin abnormalities and disabilities, eye examination, and fundoscope. The activity results were obtained from 24 respondents, 11 men and 13 women. The age range is 16-59 years (67%), with the highest level of education being Elementry School graduates, which is 11 people (46%). In the self-care questionnaire of patients, 40% behaved well, and the results of eye examinations almost suffered from dry eye complaints without disabilities.

The Relationship between ABO Blood Type and Outcomes in Severe and Critical COVID-19 Patients in the Covid ICU of the Hospital. Dr. M. Djamil Padang Adissa Benanda; Dedy Kurnia; Gardenia Akhyar
Jurnal Indonesia Sosial Sains Vol. 5 No. 08 (2024): Jurnal Indonesia Sosial Sains
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jiss.v5i08.1217

The spread of the Coronavirus Disease represents the most significant global health threat in recent decades. Blood type is among the risk factors associated with COVID-19, with certain blood types linked to increased severity and higher mortality rates. This research aims to assess the relationship between ABO blood type and outcomes in severe and critical COVID-19 patients in the ICU at RSUP Dr. M. Djamil Padang. The study is an observational analytical research utilizing a cross-sectional approach. Data were gathered from the medical records of COVID-19 patients from January to September through a total sampling method, resulting in 124 individuals meeting the inclusion criteria. The data were analyzed utilizing the Chi-Square test. The discoveries uncovered that male patients (54%) dwarfed female patients (46%). The larger part of patients were within the age range of 56-65 for years (33.9%). Patients with blood sort O were more predominant among those with extreme COVID-19 (31.3%) and basic COVID-19 (38.0%). The foremost common result was passing, happening in 56.0% of serious cases and 53.7% of basic cases. There was no factually noteworthy relationship between ABO blood sort and results in serious and basic COVID-19 patients, with a p-value of 0.778 (>0.05). The study concludes that there's no measurably critical affiliation between ABO blood sort and outcomes in extreme and basic COVID-19 patients within the ICU at Dr. M. Djamil Padang hospital.

Profil Pasien Neurodermatitis di Rumah Sakit Pendidikan Universitas Andalas Tahun 2019-2021 Nur, Fauziah; Yenny, Satya Wydya; Revilla, Gusti; Akhyar, Gardenia; Ashal, Taufik; Khaira, Fathiyyatul
Jurnal Penelitian Perawat Profesional Vol 7 No 3 (2025): Juni 2025, Jurnal Penelitian Perawat Profesional
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jppp.v7i3.5135

Tujuan penelitian ini yaitu mengidentifikasi profil pasien neurodermatitis di Rumah Sakit Pendidikan Universitas Andalas tahun 2019-2021. Jenis penelitian ini adalah penelitian deskriptif retrospektif dengan pendekatan cross-sectional. Penelitian dilaksanakan di Bagian Rekam Medis Rumah Sakit Pendidikan Universitas Andalas pada Januari 2019-Desember 2021. Teknik yang digunakan adalah total sampling dan besar sampel penelitian ini adalah 51. Analisis data menggunakan analisis univariat. Hasil penelitian ini menunjukkan usia terbanyak pasien neurodermatitis berusia 56-65 tahun yaitu 33,3%. Jenis kelamin terbanyak yaitu perempuan 58,8%. Pekerjaan terbanyak yaitu PNS dan ibu rumah tangga masing-masing 27,5%. Keluhan pasien terbanyak yaitu gatal 68,6%. Lokasi lesi paling banyak ditemukan tungkai bawah yaitu 43,1%. Terapi oral terbanyak yaitu setirizin 86,3%. Terapi topikal yang banyak digunakan yaitu emolien 76,5%. Kesimpulan penelitian ini didapatkan bahwa usia 56-65 tahun, jenis kelamin perempuan, pekerjaan PNS dan ibu rumah tangga, keluhan gatal, lokasi lesi tungkai bawah, terapi oral setirizin dan terapi topikal emolien merupakan yang paling banyak ditemukan pada pasien neurodermatitis.

A Challenge In Establishing The Etiologic Of Toxic Epidermal Necrolysis In Children Jefrizal Wirman; Gardenia Akhyar; Irdawaty Izrul; Qaira Anum
Proceeding International Conference Of Innovation Science, Technology, Education, Children And Health Vol. 2 No. 1 (2022): Proceeding of The International Conference of Inovation, Science, Technology, E
Publisher : Program Studi DIII Rekam Medis dan Informasi Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/icistech.v2i1.33

Background: Toxic epidermal necrolysis (TEN) is a rare especially in children, acute and potentially lifethreatening. The etiology of the higher incidence of TEN in various pediatric age groups than in adults is unclear, the cause is multifactorial. TEN have known triggering events, including infections (commonly viral or mycoplasma) drugs/herbs, malignancy, vaccines, and idiopathic. Case report: We reported a case TEN of a 5 years old boy. There was a history of fever and red rash on the patient's hands 5 days ago and taken paracetamol, amoxicilin, chlorpeniramin maleat(CTM), and vitamin C, then a red patch and blisters appears 12 hours later. Physical examination: composmentis, temperature 38,80C. Dermatological state: erythemathous macules, vesicles, bulla, erosions, excoriations, crusts on the most of body. Hyperemic conjunctiva, on oral mucosa there were erythematous oedem, erosion, excoriation and reddish-blackish crust, and erosion of the genitalia. Epidermolysis was about ± 40%. Laboratory examination :leucocyte 5300/mm3 with lymphocytosis. Serum urea increases, serum bicarbonate decreases. The patient was treated dexamethasone intra venous and decreased dose with prednisone oral, patient improved and healed on day 13. Discussion: The diagnosis of TEN in patients is made based on history and physical examination. We can establish a typical diagnosis of TEN from clinical symptoms and physical examination, but to find the etiology is sometimes difficult and requires a deep history and other investigations. The etiology in this case cannot be established because of drugs or infection. To find out, it is necessary to do further tests such as serology or PCR

A Challenge In Establishing The Etiologic Of Toxic Epidermal Necrolysis In Children Jefrizal Wirman; Gardenia Akhyar; Irdawaty Izrul; Qaira Anum
Proceeding International Conference Of Innovation Science, Technology, Education, Children And Health Vol. 2 No. 1 (2022): Proceeding of The International Conference of Inovation, Science, Technology, E
Publisher : Program Studi DIII Rekam Medis dan Informasi Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/icistech.v2i1.33

Background: Toxic epidermal necrolysis (TEN) is a rare especially in children, acute and potentially lifethreatening. The etiology of the higher incidence of TEN in various pediatric age groups than in adults is unclear, the cause is multifactorial. TEN have known triggering events, including infections (commonly viral or mycoplasma) drugs/herbs, malignancy, vaccines, and idiopathic. Case report: We reported a case TEN of a 5 years old boy. There was a history of fever and red rash on the patient's hands 5 days ago and taken paracetamol, amoxicilin, chlorpeniramin maleat(CTM), and vitamin C, then a red patch and blisters appears 12 hours later. Physical examination: composmentis, temperature 38,80C. Dermatological state: erythemathous macules, vesicles, bulla, erosions, excoriations, crusts on the most of body. Hyperemic conjunctiva, on oral mucosa there were erythematous oedem, erosion, excoriation and reddish-blackish crust, and erosion of the genitalia. Epidermolysis was about ± 40%. Laboratory examination :leucocyte 5300/mm3 with lymphocytosis. Serum urea increases, serum bicarbonate decreases. The patient was treated dexamethasone intra venous and decreased dose with prednisone oral, patient improved and healed on day 13. Discussion: The diagnosis of TEN in patients is made based on history and physical examination. We can establish a typical diagnosis of TEN from clinical symptoms and physical examination, but to find the etiology is sometimes difficult and requires a deep history and other investigations. The etiology in this case cannot be established because of drugs or infection. To find out, it is necessary to do further tests such as serology or PCR

Hubungan Pola Penggunaan Hand Sanitizer dengan Kejadian Dermatitis Tangan Pada Mahasiswa Program Studi Kedokteran Fakultas Kedokteran Universitas Andalas Zafira, Qory; Akhyar, Gardenia; Rustam, Erlina; Julizar, Julizar; Gustia, Rina; Afdal, Afdal
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 1 (2024): Maret 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i1.1046

Latar Belakang: Pandemi Covid-19 membuat masyarakat menjalankan pola hidup baru dengan menerapkan protokol kesehatan dengan membersihkan tangan menggunakan hand sanitizer. Hand sanitizer diformulasikan untuk dapat menghambat dan membunuh mikroorganisme dengan cara mendenaturasi lipid, namun efek dari cara kerjanya ini dapat meningkatkan risiko terjadinya dermatitis tangan. Objektif: Penelitian ini bertujuan untuk mengetahui hubungan pola penggunaan hand sanitizer dengan kejadian dermatitis tangan. Metode: Penelitian ini merupakan penelitian analitik observasional dengan metode cross-sectional study dengan teknik simple random sampling pada mahasiswa Program Studi Kedokteran Fakultas Kedokteran Universitas Andalas Angkatan 2021 dengan jumlah sampel sebanyak 80 orang. Data responden diperoleh dari kuesioner dan dianalisis menggunakan uji chi square. Hasil: Hasil penelitian ini didapatkan sebagian besar mahasiswa menggunakan hand sanitizer lebih dari 6 bulan (82,5%) dengan frekuensi 1 sampai 5 kali dalam sehari (86,3%). Lebih dari setengah mahasiswa menggosok tangan kurang dari 10 detik setiap menggunakan hand sanitizer (75%), dan tidak menggunakan pelembab (57,5%). Sebagian besar mahasiswa tidak mengalami dermatitis tangan (77,5%) dan tidak memiliki riwayat atopi (80%). Tidak terdapat hubungan yang signifikan antara durasi penggunaan, frekuensi penggunaan, durasi scrubbing penggunaan hand sanitizer dan penggunaan pelembab dengan kejadian dermatitis tangan dengan nilai p=0.599 untuk durasi penggunaan, p=0.086 untuk frekuensi penggunaan, p=1.00 untuk durasi scrubbing, dan p=0.316 untuk penggunaan pelembab. Terdapat hubungan antara riwayat atopi dengan kejadian dermatitis tangan dengan nilai p=0,000. Simpulan: Tidak terdapat hubungan yang signifikan antara pola penggunaan hand sanitizer dengan kejadian dermatitis tangan khususnya durasi penggunaan, frekuensi, dan durasi scrubbing dan penggunaan pelembab, namun terdapat hubungan antara riwayat atopi dengan kejadian dermatitis tangan. Kata kunci: Pola penggunaan hand sanitizer, dermatitis tangan

Hubungan Stadium Kanker dan Jenis Terapi yang diberikan Dengan Tingkat Kualitas Hidup Penderita Kanker Buli-Buli di RSUP Dr. M. Djamil Padang Tahun 2018–2021 Fikri Fadhil; Alvarino Alvarino; Gardenia Akhyar
Detector: Jurnal Inovasi Riset Ilmu Kesehatan Vol. 2 No. 3 (2024): Agustus : Jurnal Inovasi Riset Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/detector.v2i3.4012

Quality of life is very important assessment in evaluating a person’s perception of the disease they have. Cancer stage characteristics and the type of therapy given to baldder cancer patients can affect the overall quality of life. This study aims to see the relationship of the stage of cancer and the type of therapy given with the quality of life. The type of this research is an analytical study with a cross sectional design. Sampling was done by consecutive sampling technique. The research took place from August 2021–March 2022 at RSUP Dr. M. Djamil Padang with a total sample of 64 people. The research instrument used was the EORTC QLQ-C30 questionnaire and medical records of patients with bladder cancer. Bladder cancer most often occurs in people with the age of >45 years old and male sex. The most found stage in bladder cancer is stage II and the most frequently implemented therapy is TURBT. Cancer stage and the type of therapy used had a statistically significant relationship with the quality of life of bladder people with the age of >45 years old and male sex. The most found stage in bladder cancer is stage II and the most frequently implemented therapy is TURBT. Cancer stage and the type of therapy used had a statistically significant relationship with the quality of life of bladder cancer patients (p=0.01; p=0.04). There is a significant relationship of the cancer stage and type of therapy given with the quality of life of bladder cancer patients.

Hair Transplant Follicular Unit Extraction Technique as a Current Treatment Option for Androgenetic Alopecia Gardenia Akhyar; Nagara, Adianto Jaya
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 4 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i4.962

The therapy for androgenetic alopecia currently varies, and there is no generally efficacious form of treatment. Despite receiving therapy, a portion of individuals with alopecia still do not achieve the anticipated hair regrowth outcomes. The absence of efficacious medical intervention typically necessitates the exploration of alternative therapy modalities. A significant number of patients who do not get satisfactory results from medical treatment explore other therapeutic approaches, such as hair transplantation. Advancements in hair transplantation procedures have seen substantial progress since the 1960s. Men frequently seek hair transplantation, making it a popular cosmetic treatment. Over 11,000 operations took place in the United States in 2014. Commonly practiced contemporary hair transplant procedures include follicular unit transplantation (FUT) and follicular unit extraction (FUE). The FUE technique is gaining popularity due to its non-invasive nature, quicker recovery time, reduced post-operative discomfort, and fewer surgical scars, in contrast to the FUT approach.

The Relationship between ABO Blood Type and Outcomes in Severe and Critical COVID-19 Patients in the Covid ICU of the Hospital. Dr. M. Djamil Padang Benanda, Adissa; Kurnia, Dedy; Akhyar, Gardenia
Jurnal Indonesia Sosial Sains Vol. 5 No. 08 (2024): Jurnal Indonesia Sosial Sains
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jiss.v5i08.1217

The spread of the Coronavirus Disease represents the most significant global health threat in recent decades. Blood type is among the risk factors associated with COVID-19, with certain blood types linked to increased severity and higher mortality rates. This research aims to assess the relationship between ABO blood type and outcomes in severe and critical COVID-19 patients in the ICU at RSUP Dr. M. Djamil Padang. The study is an observational analytical research utilizing a cross-sectional approach. Data were gathered from the medical records of COVID-19 patients from January to September through a total sampling method, resulting in 124 individuals meeting the inclusion criteria. The data were analyzed utilizing the Chi-Square test. The discoveries uncovered that male patients (54%) dwarfed female patients (46%). The larger part of patients were within the age range of 56-65 for years (33.9%). Patients with blood sort O were more predominant among those with extreme COVID-19 (31.3%) and basic COVID-19 (38.0%). The foremost common result was passing, happening in 56.0% of serious cases and 53.7% of basic cases. There was no factually noteworthy relationship between ABO blood sort and results in serious and basic COVID-19 patients, with a p-value of 0.778 (>0.05). The study concludes that there's no measurably critical affiliation between ABO blood sort and outcomes in extreme and basic COVID-19 patients within the ICU at Dr. M. Djamil Padang hospital.

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