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Journal : JOURNAL LA MEDIHEALTICO

Evaluation of the Rationality of Antibiotic Use in Pneumonia Patients Using the Gyssens Method Agustiana, Agustiana; Fristiohady, Adryan; Arba, Muhammad; Jabbar, Asriullah; Akib, Nur Illiyyin; Suryani, Suryani
Journal La Medihealtico Vol. 6 No. 6 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i6.2757

Abstract

Pneumonia is one of the leading causes of morbidity and mortality worldwide. The irrational use of antibiotics in pneumonia management can reduce therapeutic effectiveness and increase the risk of antimicrobial resistance. This study aimed to evaluate the rationality of antibiotic use in pneumonia patients at Hospital X using the Gyssens method. This research employed a descriptive observational design with a retrospective approach, utilizing medical record data of adult inpatients diagnosed with pneumonia during the period of January–December 2024. A total of 86 patient records meeting the inclusion criteria were analyzed. Evaluation was conducted using the Gyssens method by comparing the appropriateness of therapy with the Guidelines for the Management of Adult Pneumonia issued by the Indonesian Ministry of Health (Regulation No. 28 of 2021) and the Infectious Diseases Society of America/American Thoracic Society (IDSA/ATS, 2023) guidelines. The results showed that the most frequently used antibiotics were Ceftriaxone (34.88%), Azithromycin (32.56%), and Levofloxacin (32.56%). The most common duration of therapy was five days (53.9%). Based on the Gyssens categories, rational antibiotic use (category 0) was found in 57 cases (66.28%), while the remaining cases were categorized as I (6.98%), IIa (11.63%), IIIa (9.30%), and IIIb (5.81%). These findings indicate that most antibiotic use at Hospital X was rational; however, continuous monitoring and periodic evaluation through the Antimicrobial Resistance Control Program (PPRA) are still necessary to optimize therapeutic effectiveness and prevent antibiotic resistance.
Co-Authors A.A. Ketut Agung Cahyawan W Achmad Fuad Hafid Agustiana, Agustiana Akib, Nurhijrianti Amalia, Afriani Amina, Amina Arba, Muhammad Ardiyanti Ardiyanti Ari Sartinah, Ari Armadhani, Fery Indradewi Aspadiah, Vica Aty Widyawaruyanti Azzahra, Dhealfa Azzahrah, Ana Aprilia Baane, Wa Basri, Lade Aburifal Chatarina Umbul Wahyuni Fadhliyah Malik Fristiohady, Adryan Halik, Halik Hamuni, Muhammad Farid Hanari, Hanari Hariati Lestari Hasnawati Hasnawati HM, Nurhayani Husnaeni, Husnaeni Husniati Husniati, Husniati Imran Imran Indahyani, Rezki Indalifiany, Astrid Irnawati Irnawati Jabbar, Asriullah Karangan, Refky Caesar Kasmawati, Henny L, Adryan Fristiohady. Listy Handayani Mahfuz, Muhammad Mahmudah, Rifa’atul Malaka, Muhammad Hajrul Mallarangeng, Andi Nafisah Tendri Adjeng Marchelda, Theyuci Mardikasari, Sandra Aulia Mubarak Mubarak Nasrudin Negoro, Wianda Puspo Nurhasana, N Nurul Karina, Nurul Pascayantri, Asniar Putri Patricia Putri, Natalia Christiani RAHMAT MULIADI, RAHMAT Rifa'atul Mahmudah Rifaldi, Aimar Rini Hamsidi Ritonga, Halimatussadiyah Rivai, Talitha Nayla Shabira Rizki, Annisa Ruslin, Ruslin Sabarudin Sabarudin Sabarudin Sabarudin Sahidin . Saputra, Muhammad Juharisman Saputri, Wanda Januarty Sari, Annisa Purnama Sida, Nurramadhani A. Silondae, Andini Risky Khaerunnisa Siti Nurfadilah H Solo, Dian Munasari Suci Wahyuni Sugireng, Sugireng Sukma, Tsaqila Aulia SURYANI Suryani Suryani Syamsiar, Syamsiar Tasnim Tasnim Utami, Andi Rafita Ayu Risky W Wahyuni, W wahyuni wahyuni Waode, Nurul Wiwied Ekasari Wulandari, Inten Widuri Y, Muhammad Ilyas Yamin, Y Zubaydah, Wa Ode Sitti Zubaydah, Wa Ode Sitti