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All Journal Biotika: Jurnal Ilmiah Biologi Bionatura Farmaka Indonesian Journal of Applied Sciences Jurnal Ilmu Dasar Jurnal Natur Indonesia Jurnal Radioisotop dan Radiofarmaka Pharmaciana: Jurnal Kefarmasian Indonesian Journal of Cancer Chemoprevention Indonesian Journal of Pharmaceutical Science and Technology Jurnal Farmasi Klinik Indonesia Global Medical and Health Communication Indonesian Journal of Science and Technology MPI (Media Pharmaceutica Indonesiana) INDONESIAN JOURNAL OF PHARMACY Pharmascience IDJP (Indonesian Journal of Pharmaceutics) Indonesian Journal of Chemistry PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Majalah Farmasetika Jurnal Ilmiah Farmako Bahari Indonesian Journal of Biological Pharmacy Jurnal Sains dan Teknologi Farmasi Indonesia Praeparandi : Jurnal Farmasi dan Sains Journal of Pharmaceutical and Sciences. Jurnal Sains dan Kesehatan
Anas Subarnas
Departemen Farmakologi Dan Farmasi Klinik, Fakultas Farmasi, Universitas Padjadjaran, Sumedang
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Dentistry Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Public Health

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Journal : IDJP (Indonesian Journal of Pharmaceutics)

 1 
Preparation of organic-solvent free liposome of Piper albi Linn extract in solution and powder form Eri Amalia; Iyan Sopyan; Norisca Aliza Putriana; Sriwidodo Sriwidodo; Anas Subarnas
Indonesian Journal of Pharmaceutics Vol 3, Issue 3, Sept - Dec 2021
Publisher : Universitas Padjadjaran (Unpad)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/idjp.v3i3.38335

Abstract

Piperine is bioactive alkaloid extracted from white pepper (Piper albi Linn) with several beneficial pharmacological activities. It is also known to enhance the bioavailability of several limited solubilities of other compounds such as curcumin and resveratrol. Nevertheless, due to its poorly water-soluble character, piperine and extract of white pepper are less applied among other plant extracts. Therefore, our research focussed on the engineering of white pepper extract standardized to piperine in liposome solution and liposome powder for further preparation of various pharmaceutical dosage forms.Our research in preparation of extracted white pepper in liposome delivery system successfully prepared spheric liposome solution with 98.92%±1.17% and an average size of 398.7 nm. The liposome was also successfully prepared in dry powder form with sucrose as a carrier for liposome protection. The rehydration is successfully forming a spheric shape with a similar profile to the initial liposome solution. This research paves the way for scalable white pepper extract liposome preparation without the utilization of toxic organic solvent, to produce the commercial solvent-free product in the future.Keywords: Piperine, Piper albi Linn, liposome, extract, organic solvent-free, drug delivery system, spray dry 
Antioxidant Activities of Muntingia calabura, Syzygium cumini, Ocimum basilicum, and Eleutherine bulbosa using DPPH Method Ani Haerani; Anis Yohana Chaerunisa; Anas Subarnas
Indonesian Journal of Pharmaceutics Vol 1, Issue 2, May - August 2019
Publisher : Universitas Padjadjaran (Unpad)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (6387.771 KB) | DOI: 10.24198/idjp.v1i2.21531

Abstract

Antioxidants are substances that can provide endogenous protection and exogenous oxidative stress by capturing free radicals. Many plants are efficacious as antioxidants, namely plants that contain polyphenols, especially flavonoids, so many are formulated as natural antioxidants. Plants such as Muntingia calabura, Syzygium cumini, Ocimum basilicum, and Eleutherine bulbosa contain polyphenol compounds, especially flavonoids which are efficacious as natural antioxidants. This research aimed to study antioxidant activity derived from some potential plants using the DPPH method by calculating the IC50 value of each plant extract. This research method starts from the determination process to prove the validity of the plants used, the extraction process using the maceration method with 70% ethanol solvent, then the antioxidant activity of extracts from each plant was carried out using the DPPH method. This research starts from the determination process to ensure the correctness of the plants used, then the extraction process is carried out using the maceration method with 70% ethanol solvent. After that the antioxidant activity was determined from the four plants using the DPPH method to see the strongest IC50 value among the four plants. IC50 is the concentration of the sample to inhibit 50% of free radicals. The results of IC50 values from ethanol extract of M. calabura leaves, Syzygium cumini leaves, Ocimum basilicum leaves and Eleutherine bulbosa bulbs, were 18.72; 63,84; 141.59 and 173.15 ppm. Ethanol extract of M. Calabura has a smaller IC50 value of 18.72 ppm which has a very strong and most powerful antioxidant from the ethanol extract of Syzygium cumini, Ocimum basilicum and Eleutherine bulbosa. Keywords : Antioxidant, Muntingia calabura, Syzygium cumini, Ocimum basilicum, Eleutherine bulbosa, DPPH Method
Co-Authors Abdul Mutalib Abdul Mutalib Adang Hardi Gunawan Adryan Fristiohady Afiat Berbudi Agung W.M. Yodha Aji Najihudin ALIF VIRISY BERLIAN AMELIA SUCI PRAFITRI YANI Ami Tjitraresmi Andini Sundowo Ani Haerani ANI HAERANI Anis Chaerunisaa Anis Yohana Chaerunisa ANIS YOHANA CHAERUNISA Anis Yohana Chaerunisaa Anis Yohana Chaerunisaa Anton Apriyantono ASENG RAMLAN Asep Nurrahman Yulianto ASMAN SADINO, ASMAN Aulia Annisa Putri Heri Aulia, Nazela Constantia Hilyatul Belinda, Rahma BRIGITTA TIARA PUTRI PRIYANTONO California, Salma H. Chaerunisaa, Anis Cucu Hadiansyah Dana Nasrullah Dani Sujana Dea A. A. Kurniasih DIAH SITI FATIMAH DIANTINI, AJENG - Dicky Santosa Dida Akhmad Gurnida Dika Destiani Dingse Pandiangan - ELI HALIMAH Eli Halimah, Eli Ellin Febrina Elvan Kamal Endang Sutedja Eri Amalia Euis Julaeha Fauzia Azzahra Fazrina Pratiwi Fransiska Silalahi Henni Djuhaeni Henni Djuhaeni Herri S. Sastramihardja Hesti Renggana Hideo Hayashi Hideo Hayashi Hideo Hayashi Hideo Hayashi HIRALIUS BIMA ARDIKA PUTRA I. Sahidin IIN SUPARTINAH NOER Indradi, Raden Bayu Irma Erika Herawati Iyan Sopyan Joharudin, Ade Juliani Ronike Turang Jutti Levita Karyono - Keri Lestari Khoirunnisa, Afina Khoziah Ahmad, Khoziah Kunkun J. Gurmaya Kurniasih, Dea A. A. Lika Ginanti Febriana Lutfi Sulaiman M. S. Soedjanaatmadja Magdarita Riwu Mardhiani, Yanni Dhiani Marline Abdassah Bratadiredja Martalena Ramli Maulana Yusuf Alkandahri Mega Juliana Moelyono Moektiwardoyo, Moelyono Mohammad Ghozali Muchtaridi Muchtaridi Mutiara, Intan Najihudin, Aji Nasrudin Nasrudin Nela - Simanjuntak NONI CAHYANA Noor Rain Abdullah Noor Rain Abdullah Nor Latifah Norisca Aliza Putriana NUR ALFI KUSUMAH DEWI PARAS WATI Pramesti, Ardhia Kirana Prayudi Ahmad Puja Yanti Raden Maya Febrianti Rano K. Sinuraya Ratu Ralna Ismuha Renggana, Hesti Resmi Mustarichie Riezki Amalia Risrina Nur Ekawati Rizkita Rahmi Esyanti - Ronny Lesmana Salma H. California Shinta Marpaung Sinuraya, Rano K. Siti Saidah Muthmainah Slamet Budijanto Sofa Fajriah Sri Adi Sumiwi Sri Hartini Sriwidodo Sriwidodo Supriyatna ., Supriyatna Supriyatna Supriyatna Supriyatna Sutardjo Supriyatna Sutardjo Supriyatna Sutardjo Supriyatna Sutardjo Surachman, Emma Suseno Amien Suwandi, Deden Winda Syafrudin Purnama Sidiq, Syafrudin Purnama Taofik Rusdiana Tati Herlina Tati Herlina Tati Herlina Tati Herlina Tina Rostinawati Triyono Triyono Triyono Triyono Unang Supratman Utami, Putri Antiyani W. Wahyuni Wenny Tilaar - Yohana Chaerunisaa, Anis Yoppi Iskandar Yulianto, Asep Nurrahman Yuni Elsa Hadisaputri