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All Journal HAYATI Journal of Biosciences Jurnal Farmasi Udayana Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Indonesian Journal of Pharmaceutical Science and Technology MPI (Media Pharmaceutica Indonesiana) As-syifaa Jurnal Farmasi Jurnal SOLMA Jurnal Jamu Indonesia BERNAS: Jurnal Pengabdian Kepada Masyarakat J.Abdimas: Community Health Jurnal Mitra Masyarakat (JMM) Society: Jurnal Pengabdian Masyarakat Pharmaceutical Sciences and Research (PSR) Borneo Journal of Pharmacy Jurnal Pengabdian Farmasi dan Sains Indonesian Journal of Jamu
Ni Putu Ermi Hikmawanti
Departemen Biologi Farmasi, Fakultas Farmasi Dan Sains, Universitas Muhammadiyah Prof. DR. HAMKA, DKI Jakarta 13460, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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EDUKASI MENGENAI PENGOLAHAN DAN PEMANFAATAN TANAMAN OBAT SEBAGAI PENINGKAT SISTEM IMUN DI ERA ADAPTASI KEBIASAAAN BARU PADA KADER PKK RW 05 KELURAHAN MALAKA SARI JAKARTA TIMUR Ni Putu Ermi Hikmawanti1*, Agustin Yumita2, Nora Wulandari3
Jurnal Mitra Masyarakat Vol. 2 No. 1 (2021): Jurnal Mitra Masyarakat
Publisher : STIKes Mitra Keluarga

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Abstract

Penerapan adaptasi kebiasaan baru (new normal) saat pandemi akibat infeksi corona (Covid-19) menjadikan lingkungan keluarga di rumah tangga merupakan kelompok kecil dalam masyarakat yang merupakan awal dari terciptanya sistem imunitas yang lebih luas. Melalui edukasi kepada ibu sebagai kunci utama dalam manajemen kesehatan di rumah tangga maka pengendalian segera infeksi virus ini diharapkan dapat terwujud, salah satunya dengan pemanfaatan tanaman obat secara tradisional. Kegiatan ini dilatarbelakangi oleh belum adanya pelatihan dan penyuluhan secara langsung kepada warga mengenai pengolahan dan pemanfaatan tanaman obat tradisional kepada ibu-ibu kader PKK RW 05 Kelurahan Malaka Sari Jakarta Timur. Kegiatan pengabdian masyarakat yang dilakukan meliputi pembekalan pengetahuan mengenai: 1). pentingnya sistem imunitas dan cara menjaganya di masa pandemi, 2). tanaman obat tradisional dan manfaat dalam meningkatkan sistem imunitas, 3). cara mengolah tanaman obat tradisional yang benar dan tepat, sehingga efek yang diinginkan dapat tercapai. Hasil survei menunjukkan bahwa 72,2% responden membuat ramuan tanaman obat tradisional sendiri, sebanyak 66,7% meracik sesuai takaran sendiri dan 54,2% merasakan manfaatnya. Edukasi yang diberikan harapannya mampu meningkatkan pengetahuan Ibu-ibu PKK yang mayoritas mengolah ramuan tanaman obat tradisional secara mandiri, sehingga dapat menerapkannya dengan tepat dan benar
EDUKASI DAN PELATIHAN PEMBUATAN MAKANAN DAN MINUMAN DAN MINUMAN PROBIOTIK UNTUK MENJAGA IMUNITAS KELUARGA SELAMA PANDEMI Nora Wulandari; Tuti Wiyati; Ni Putu Ermi Hikmawanti; Agustin Yumita; Daniek Viviandhari
Jurnal Mitra Masyarakat Vol. 2 No. 2 (2021): Jurnal Mitra Masyarakat
Publisher : STIKes Mitra Keluarga

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Abstract

Terdapat banyak hal yang dapat dilakukan selama masa pandemi sebagai usaha untuk menjaga imunitas tubuh.Selain pamanfaatan tanaman obat dan vitamin, probiotik diketahui dapat menjaga imunitas tubuh. Dalamperkembangannya probiotik banyak dimanfaatkan untuk pembuatan makanan dan minuman yang sehat, enak danmenarik. Kegiatan pengabdian ini dilakukan untuk memberikan edukasi dan pelatihan kepada masyarakatmengenai probiotik dan pemanfaatannya dalam pembuatan makanan dan minuman untuk menjaga imunitas tubuhkeluarga selama pandemi. Kegiatan pengabdian kepada masyarakat ini dilakukan pada tanggal 14 Juli 2021 Pukul10.00-13.00 WIB pada masyarakat kecamatan Martapura OKU timur Sumatera Selatan. Hasil yang didapatkanpada kegiatan ini terdapat peningkatan pengetahuan peserta setelah diberikan edukasi mengenai probiotik danpemanfaatannya. Peserta sangat mendukung kegiatan seperti ini untuk dilakukan sehingga tidak hanyameningkatkan pengetahuan masyarakat tetapi juga bisa menjadi ide usaha pada ibu-ibu rumah tangga.
Chemical Components of Ocimum basilicum L. and Ocimum tenuiflorum L. Stem Essential Oils and Evaluation of Their Antioxidant Activities Using DPPH Method Hikmawanti, Ni Putu Ermi; Hariyanti,; Nurkamalia,; Nurhidayah, Sahera
Pharmaceutical Sciences and Research Vol. 6, No. 3
Publisher : UI Scholars Hub

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Abstract

Ocimum basilicum L. and Ocimum tenuiflorum L. are two types of plants from Ocimum (Lamiaceae). One of their chemical compounds is essential oil. Essential oil might have an antioxidant activities. The part of the plants which are often wasted and never used are stem. This study aimed to analyze the chemical components of O. basilicum L. and O. tenuiflorum L. stem essential oils and evaluate their antioxidant activities. Essential oils were obtained by steam-water distillation. Analysis of chemical component of essential oil was performed using Gas Chromatography-Mass Spectroscopy (GC-MS). Antioxidant activities were evaluated with DPPH method and then the IC50 value was determined as 50% inhibition concentration of free radical. The results showed that O. basilicum L. stem essential oil had 13 components with the major compounds were methyl eugenol (52.60%), caryophyllene (18.75%), and germacrene-D (9.19%). Whereas, O. tenuiflorum L. stem essential oil had 11 components with the major compounds were α-copaene (5.56%), caryophyllene (17.28%), germacrene-D (9.29%) and methyl eugenol (56.72%). IC50 value of O. basilicum L. stem essential oil was 17.50 µg/mL, whereas IC50 value of O. tenuiflorum L. stem essential oil was 14.17 µg/mL. It was concluded that both oils might be good natural antioxidant agents.
Aktivitas Afrodisiaka Fraksi dari Ekstrak Etanol 70% Daun Katuk (Sauropus androgynus (L). Merr) Pada Tikus Putih Jantan Rusdi, Numlil Khaira; Hikmawanti, Ni Putu Ermi; Maifitrianti, Maifitrianti; Ulfah, Yuanita Sofiana; Annisa, Ayyoehan Tiara
Pharmaceutical Sciences and Research Vol. 5, No. 3
Publisher : UI Scholars Hub

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Abstract

Decreased of libido is illustrated with disinterest in sexual activity caused by erectile dysfunction, impotence, and infertility. It can be treated by aphrodisiac agents. Katuk or Sauropus androgynus (L). Merr has long been used as a medicinal plant. The aim of this research was to evaluate which fraction of katuk leaf ethanol extract that had the aphrodisiac activity with parameters of climbing, introduction and the weight of testicular and seminal vesicle of male rat. Sprague-Dawley male rats as animals model divided into five groups: the normal control group, the positive control group (X-gra®), the n-hexane, ethyl acetate and water fraction groups in which each fraction group given a dose of 11.85 mg/kg body weight. The number of climbing and introductions were calculated on 0, 1st, 3th, and 5th day. The data were tested statistically with one-way ANOVA test followed by Tukey test. The weight of testicular and seminal vesicle of male rat were observed on the 15th day. Previously, rats were anesthetized using ketamine and then performed surgery. The results showed that the n-hexane fraction (11.85 mg/kg body weight) increased libido with the average number of climbing was 16.5 times and the average number of introductions was 27.75 times. It was also able to increase the weight of testicular and seminal vesicle of male rat compare to positive control (X-gra® 51.37 mg/kg body weight). The compounds contained in n-hexane fraction are terpenoids and steroids.
The Effect of Pre-Extraction Preparation on Antioxidant Compounds of Sauropus androgynus (L.) Merr. Leaves Extracts Hikmawanti, Ni Putu Ermi; Fatmawati, Sofia; Arifin, Zainal; Cahyaningrum, Niken; Arif Fauzan, Muhammad
Pharmaceutical Sciences and Research Vol. 8, No. 3
Publisher : UI Scholars Hub

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Abstract

Sauropus androgynus (L.) Merr. (Phyllanthaceae) is a green vegetable. It is rich in natural antioxidant compounds such as phenolics and flavonoids. The pre-extraction preparation can affect the results of extracting compounds from natural materials. This study aims to determine the effect of pre-extraction procedures, including sample form (fresh/dried), drying process (oven-drying/indirect sunlight-drying/air-drying), and particle size (ground/powdered) on total phenolic and flavonoid levels of ethanolic extracts of S. androgynus leaves and their antioxidant activity against DPPH radicals. S. androgynus leaves were extracted using the cold maceration method. The total phenolic and flavonoid contents of the extract were determined by the colorimetric method using a UV-Vis spectrophotometer. Antioxidant activity was measured based on the ability of the extracts to reduce DPPH free radicals. The results showed that the pre-extraction preparation influenced the antioxidant components obtained in S. androgynus leaves. According to sample form, fresh leaves contained a higher phenolics and flavonoids (33.66 mg GAE/g and 11.61 mg QE/g, respectively) than dried leaves. Whereas according to particle size, powdered dried leaves have higher phenolics and flavonoids content (45.12 mg GAE/g and 12.54 mg QE/g, respectively) than ground dried leaves. The leaves drying method that produced the highest phenolic content was oven-drying (47.08 mg GAE/g), while the one with the highest flavonoid content was air-drying (8.87 mg QE/g). All extracts had IC50 values against DPPH radicals around 85.71-93.91 ppm. Pre-extraction preparation in optimum condition makes the extraction process more efficient and effective in obtaining the target compounds with antioxidant activities.
IDENTIFIKASI KUALITATIF FENOLIK DAN PENAPISAN AKTIVITAS PEREDAMAN RADIKAL DPPH MENGGUNAKAN KLT PADA EKSTRAK BATANG Pluchea indica L. Ni Putu Ermi Hikmawanti; Agustin Yumita; Jihan Esa Siregar
As-Syifaa Jurnal Farmasi Vol 14, No 2 (2022): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v14i2.812

Abstract

Pluchea indica L. (beluntas) from the Asteraceae is a plant known to be rich in phenolics. Studies on the phenolic content of P. indica stems have not been explored much. The purpose of this study is to qualitatively identify the presence of phenolic compounds and to screen for the radical scavenging ability of DPPH in P. indica stem extracts using the TLC method. Extraction was carried out with the ultrasonic directly and sequentially using 50% ethanol as solvent. Separation was carried out on a silica gel plate GF254 with ethyl acetate: water: formic acid: toluene (20:2:2:1) as the mobile phase. Gallic acid and chlorogenic acid were used as comparisons. Identification of the presence of phenolic using FeCl3 5% as a spray reagent, while screening for radical scavenging activity using DPPH 0.1 mM as a spray reagent. The results showed that the 50% ethanol extracts of P. indica stems, both obtained from direct and stratified extraction, indicated the presence of phenolic compounds as antioxidants. The phenolic compounds detected were identical to gallic acid and chlorogenic acid, respectively, at hRf values of 89.4 and 55.3. The development of phenolic utilization from P. indica stems as a source of antioxidants still needs to be studied.
DISEMINASI HASIL PENELITIAN UMBI BIT UNTUK MENGATASI KONDISI ANEMIA DAN PELATIHAN PEMBUATAN PRODUK MINUMAN SEGAR PRAKTIS BERBAHAN DASAR UMBI BIT PADA WARGA RT 014 MALAKA SARI JAKARTA TIMUR Ni Putu Ermi Hikmawanti; Tuti Wiyati
Jurnal Mitra Masyarakat Vol. 3 No. 2 (2022): Volume 3 Nomor 2: Jurnal Mitra Masyarakat
Publisher : STIKes Mitra Keluarga

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Abstract

Kondisi dimana jumlah sel darah merah atau konsentrasi hemoglobin berada di bawah batas normal disebut anemia. Kondisi ini dapat disebabkan oleh (salah satunya) defisiensi mikronutrien zat besi, asam volat, vitamin, dan mineral akibat pola makan dan hidup yang tidak sehat. Secara global, hampir 42% anak dan 40% wanita hamil menderita anemia. Telah banyak penelitian terhadap tanaman, salah satunya adalah bit (Beta vulgaris), yang dapat diolah sederhana dan dikonsumsi di keluarga untuk memenuhi kebutuhan mikronutrien yang dibutuhkan oleh tubuh. Beberapa penelitian dari bit pada hewan coba sebagai pembuktian manfaat bit yang menjadi suatu sumber komponen kimia yang berkhasiat untuk mengatasi anemia telah berhasil dilakukan dan telah dipublikasikan pada jurnal Nasional dan Internasional bereputasi. Sarana penyampaian informasi berupa diseminasi terkait hasil pembuktian ilmiah tersebut sangat dibutuhkan oleh masyarakat. Warga RT 014 Malaka Sari Jakarta Timur yang menjadi sasaran kegiatan merupakan kelompok warga yang berlokasi di sekitar kampus Fakultas Farmasi dan Sains UHAMKA dan memiliki jumlah penduduk produktif yang padat. Pelatihan pembuatan minuman kesehatan yang praktis dengan bahan dasar umbi bit juga dilakukan pada kegiatan ini. Evaluasi dari kegiatan dipantau menggunakan kuesioner sebelum dan setelah pelaksanaan kegiatan. Berdasarkan kuesioner, diperoleh hasil bahwa terjadi peningkatan pengetahuan peserta mengenai manfaat bit untuk mengatasi anemia dan kemampuan peserta dalam hal membuat dan menyajikan minuman kesehatan berbahan dasar bit pada warga RT 014 Malaka Sari.
Workshop Penentuan Parameter Spesifik dan Non Spesifik Bahan Baku Obat Tradisional pada Mahasiswa Farmasi UHAMKA Melalui PKKM agustin yumita; Ni Putu Ermi Hikmawanti; Fujianti; Novia Delita
BERNAS: Jurnal Pengabdian Kepada Masyarakat Vol. 4 No. 1 (2023)
Publisher : Universitas Majalengka

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (419.417 KB) | DOI: 10.31949/jb.v4i1.3722

Abstract

Indonesia's abundant biodiversity provides good opportunities for developing medicines, especially traditional medicines made from plant materials. However, it is necessary to standardize the process to realize quality, safe, and efficacious traditional medicinal preparations. This standardization process is essential. This workshop aims to provide information on the standardization of raw materials for traditional medicines to have the knowledge and ability to standardize medicinal raw materials. At the initial stage, participants will be given a pretest. Furthermore, participants studied specific and non-specific parameters, and at the last stage, the participants were given a posttest. The data obtained from the pretest and posttest will then be processed using Excel and the IBM SPSS Statistics version 25.0 application. From the results of the workshop activities, the average value of the pretest results was 62.5806, smaller than the posttest results of 83.2258. This indicates a significant difference of P < 0.05 between the pretest and posttest. In this workshop, the team provided an understanding to the participants in standardizing the raw materials for traditional medicines. The statistical results also showed a significant effect on the treatment before being given training and after being given training to the workshop participants.
Phenolics and Flavonoids Content of Wijaya Kusuma Leaves Fractions using Micro-plate Based Assay Ni Putu Ermi Hikmawanti; Agustin Yumita; Muhammad Rafiq; Lusiana Lusiana
Indonesian Journal of Pharmaceutical Science and Technology Vol 10, No 1 (2023)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v10i1.35828

Abstract

Epiphyllum oxypetalum (DC.) or Wijaya Kusuma (Cactaceae) is an ornamental plant which is knownto contain polyphenol compounds. The purpose to determine the levels of total phenolic and flavonoidcompounds in the fractions of Wijaya Kusuma leaves using microplate-based assay. Each sample wasdetermined phenolic content with Folin-ciocalteu reagent and flavonoid content using AlCl3 on themicroplate. Absorption was measured using a microplate reader. Screening of DPPH radical scavengingactivity was identified using the TLC method. The results showed that the extract and fractions ofthe leaves of Wijaya Kusuma contained phenolic and flavonoid compounds. The ether fraction hadthe highest phenolic content (35,912±0,54776 mgGAE/g) and flavonoids (0,773±0,008 mgQE/g)compared to other fractions (ether>water>ethyl acetate fraction). There is one yellow spot with an Rfvalue of 0,85 in the ether fraction which is thought to be a compound capable of scavenging the DPPHradicals. The ether fraction of Wijaya Kusuma leaves has potential as a source of polyphenols withantioxidant activity. However, further research is needed to evaluate the antioxidant capacity in theether fraction of Wijaya Kusuma leaves.Keywords: Antioxidant, Epiphyllum oxypetalum (DC.) Haw, Flavonoids, Fraction, High-throughputMicroplate Assay, Phenolics.
Microscopical Evaluation and TLC Analysis of Pluchea indica (L.) Less: Leaf, Stem, and Root Ni Putu Ermi Hikmawanti; Fadlina Chany Saputri; Arry Yanuar; Ratih Asmana Ningrum; Abdul Mun'im; Hayati Hayati
HAYATI Journal of Biosciences Vol. 31 No. 1 (2024): January 2024
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.31.1.71-81

Abstract

Pluchea indica (L.) Less is traditionally utilized to treat postpartum women in Indonesia. The plant has many pharmacological properties, so that it can be further developed as herbal medicine. In that development process, plant authentication is needed to ensure the quality of raw materials. A simple microscopical and thin-layer chromatography (TLC) analysis might be a way to authenticate the plant, but it has never been reported. So, this study evaluates the microscopical and TLC analysis for P. indica authentication in standardized herbal medicines production. Plant microscopic observation, fluorescence analysis, and polyphenol screening were conducted. n-Hexane, ethyl acetate, and methanol extracts of plant organs were then analyzed by TLC. Here, we reported that in microscopical analysis the simplicia of P. indica contains trichomes and tannin-containing cells. In addition, chlorogenic acid as a marker was present in TLC analysis by ethyl acetate-water-formic acid-acetic acid (8.5:1.5:1:1, v/v). The results of this evaluation might provide additional information in the identification, authentication, and quality control of P. indica as a raw material for herbal medicine.
Co-Authors Abdul Mun'im Agustin Yumita Agustin Yumita Agustin Yumita Agustin Yumita Ajeng Istiningtyas Wahyudi Putri Annisa, Ayyoehan Tiara Arif Fauzan, Muhammad Arry Yanuar Ashfiya , Shafna Raudlatul Aulia, Cahya Aulia, Cahya Ayyoehan Tiara Annisa Az-zahra, Siti Fatimah Cahya Aulia Cahyaningrum, Niken Chandra Adam Lesmana Chatarina Umbul Wahyuni Daniek Viviandhari Endang Hanani Endang Hanani Fadlina Chany Saputri Faradisa, Shafira Fatmawati, Sofia Fujianti Hadi Sunaryo Hadi Sunaryo Hariyanti Hariyanti Hariyanti, Hayati Hayati Hayati Hayati Jihan Esa Siregar Lusiana Lusiana Maharani, Shintia Maifitrianti Maifitrianti Maifitrianti Maifitrianti, Maifitrianti Mardiyanti, Rini Muhammad Rafiq Nora Wulandari Novia Delita Numlil Khaira Rusdi, Numlil Khaira Nurhasna, Nurhasna Nurhasnah Nurhasnah Nurhasnah Nurhidayah, Sahera Nurkamalia, Prasetyo, Rachmad Eka Prasetyo, Rachmad Eka Putri, Ajeng Istiningtyas Wahyudi Rachmad Eka Prasetyo Ratih Asmana Ningrum Shintia Maharani Silvy Yulida Sofia Fatmawati Tuti Wiyati Tuti Wiyati Tuti Wiyati Ulfah, Yuanita Sofiana Vesya Putri Viransa Vindianita . Viransa, Vesya Putri Viransa, Vesya Putri Wiyati, Tuti Wiyati, Tuti Yeni Andriyani Yeni Andriyani Yuanita Sofiana Ulfah Yumita, Agustin Zainal Arifin