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All Journal HAYATI Journal of Biosciences Jurnal Farmasi Udayana Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Indonesian Journal of Pharmaceutical Science and Technology MPI (Media Pharmaceutica Indonesiana) As-syifaa Jurnal Farmasi Jurnal SOLMA Jurnal Jamu Indonesia BERNAS: Jurnal Pengabdian Kepada Masyarakat J.Abdimas: Community Health Jurnal Mitra Masyarakat (JMM) Society: Jurnal Pengabdian Masyarakat Pharmaceutical Sciences and Research (PSR) Borneo Journal of Pharmacy Jurnal Pengabdian Farmasi dan Sains Indonesian Journal of Jamu
Ni Putu Ermi Hikmawanti
Departemen Biologi Farmasi, Fakultas Farmasi Dan Sains, Universitas Muhammadiyah Prof. DR. HAMKA, DKI Jakarta 13460, Indonesia
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Pharmacognosy, Phytochemical, and Pharmacology of Wijaya Kusuma (Epiphyllum oxypetalum (DC.) Haw.) – An Update Review Chandra Adam Lesmana; Ni Putu Ermi Hikmawanti; Agustin Yumita
Borneo Journal of Pharmacy Vol. 5 No. 2 (2022): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v5i2.3342

Abstract

In Indonesia, Epiphyllum oxypetalum (DC.) Haw. is known as Wijaya Kusuma. The plant is grown for home decorating and used widely as medicine in some areas. This narrative review discusses the pharmacognosy, phytochemical, and pharmacology aspects of E. oxypetalum. The review is limited to original articles and abstracts available in Science Direct, PubMed, and Google Scholar. The keyword used to search the articles was “Epiphyllum oxypetalum”. The plant contains proteins, amino acids, alkaloids, saponins, terpenoids, steroids, flavonoids, tannins, glycosides, and resins. The plant has pharmacological activities such as anti-inflammatory, antimicrobials, antidiabetic, and antioxidant properties. Researchers interested in developing E. oxypetalum as a medicinal plant might use this review as a reference.
Workshop Penentuan Parameter Spesifik dan Non Spesifik Bahan Baku Obat Tradisional pada Mahasiswa Farmasi UHAMKA Melalui PKKM agustin yumita; Ni Putu Ermi Hikmawanti; Fujianti; Novia Delita
BERNAS: Jurnal Pengabdian Kepada Masyarakat Vol. 4 No. 1 (2023)
Publisher : Universitas Majalengka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31949/jb.v4i1.3722

Abstract

Indonesia's abundant biodiversity provides good opportunities for developing medicines, especially traditional medicines made from plant materials. However, it is necessary to standardize the process to realize quality, safe, and efficacious traditional medicinal preparations. This standardization process is essential. This workshop aims to provide information on the standardization of raw materials for traditional medicines to have the knowledge and ability to standardize medicinal raw materials. At the initial stage, participants will be given a pretest. Furthermore, participants studied specific and non-specific parameters, and at the last stage, the participants were given a posttest. The data obtained from the pretest and posttest will then be processed using Excel and the IBM SPSS Statistics version 25.0 application. From the results of the workshop activities, the average value of the pretest results was 62.5806, smaller than the posttest results of 83.2258. This indicates a significant difference of P < 0.05 between the pretest and posttest. In this workshop, the team provided an understanding to the participants in standardizing the raw materials for traditional medicines. The statistical results also showed a significant effect on the treatment before being given training and after being given training to the workshop participants.
Peningkatan Pengetahuan Mengenai Penyakit Kardiovaskular dan Manfaat Konsumsi Sayur dan Buah Pada Masyarakat Desa Pasir Angin, Cileungsi, Jawa Barat Wiyati, Tuti; Nurhasna, Nurhasna; Hikmawantia, Ni Putu Ermi
Society : Jurnal Pengabdian Masyarakat Vol 2, No 3 (2023): Mei
Publisher : Edumedia Solution

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55824/jpm.v2i3.271

Abstract

Cardiovascular disease is still at the top cause of death in Indonesia and globally. Cardiovascular diseases include hypertension, stroke, and heart disease. Knowledge is still ignored and also an unhealthy lifestyle caused increasing worse risk of its. The aim was to educate about the knowledge of cardiovascular disease and the importance of consuming vegetables and fruits as preventive and treatment of its in community of Pasir Angin Village, Cileungsi, West Java. The implementation method started with education through explanation of cardiovascular disease followed by providing information on the content of active compounds in vegetables and fruits that is beneficial for its. The succeeded of this activity was analized by the average pre-test and post-test and feed back that actually seemed by some reacted of pasticipants on discussed session. From the results has known that the knowledge of participants before being given education was 65%, increasing to 81%. Conclusion: cardiovascular disease education is still very much needed in communities widely.
Peningkatan Pengetahuan Pangan Sehat Aman Serta Kemampuan Pembuatan Bekal Sehat Anak Pada Orang Tua Murid TK Khalifah Jakarta 1: Improving the Knowledge of Safe Healthy Food and The Ability to Make Healthy Meals for Children in Parents of Students at TK Khalifah Jakarta 1 Hikmawanti, Ni Putu Ermi; Fatmawati, Sofia; Wiyati, Tuti
J.Abdimas: Community Health Vol 5 No 1 (2024): J.Abdimas: Community Health - Mei 2024
Publisher : LPPM STIKES Guna Bangsa Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30590/jach.v5n1.662

Abstract

Children are an age group that experiences a period of rapid growth and development during this phase of life, so healthy and safe food intake is needed to support optimal growth and development. Therefore, education about healthy and safe food for parents (guardians) is expected to maintain children's health and build healthy lifestyles for them into adulthood. The aim of implementing this community service program (PPM) is to help increase the knowledge of parents (and guardians) in determining healthy and safe food for children and families. The target of delivering this PPM is to parents (and guardians) of students at TK Khalifah Jakarta 1, located around the Faculty of Pharmacy and Science Campus, UHAMKA, East Jakarta. Implementation of PPM is carried out through the socialization of healthy and safe food materials. Training on making and packaging healthy lunches is also carried out in this activity involving parents (and guardians). Evaluation of the success of this PPM activity is assessed using a questionnaire given before and after the implementation of the activity. Based on statistical analysis, the results showed that there was an increase in knowledge of healthy and safe food and the ability of parents (and guardians) of students to make healthy provisions for children by 72.2% (a=0.05).
Analisis Flavonoid pada Fraksi Hasil Hidrolisat Ekstrak Daun Cordia sebestena L. Hikmawanti, Ni Putu Ermi; Hanani, Endang; Mardiyanti, Rini
Indonesian Journal of Pharmaceutical Science and Technology Vol 11, No 1 (2024)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v11i1.38849

Abstract

Cordia sebestena L. (Boraginaceae) atau Cordia merupakan tanaman hias dengan kandungan flavonoid. Penelitian ini bertujuan menganalisis senyawa flavonoid pada fraksi hasil hidrolisat ekstrak etanol 70% daun Cordia. Penelitian terbagi menjadi 7 tahapan, yaitu (1) maserasi daun menggunakan etanol 70%, (2) hidrolisis asam pada ekstrak dengan HCl 2N pada 95 °C selama 2 jam, (3) fraksinasi hidrolisat dengan etil asetat, (4) penentuan kadar flavonoid total dengan kolorimetri, (5) pengujian aktivitas antiradikal terhadap 2,2’-difenil-1-pikrilhidrazil (DPPH), (6) pemisahan flavonoid menggunakan kromatografi lapis tipis (KLT), dan (7) identifikasi flavonoid menggunakan spektrofotometri UV-Vis dan infra merah. Hasil menunjukan kadar flavonoid total fraksi etil asetat sebesar 8,20 mgQE/g dengan nilai IC50 terhadap radikal DPPH sebesar 296,91 µg/mL. Kromatogram KLT menunjukkan keberadaan satu bercak senyawa pada fraksi etil asetat dengan nilai hRf adalah 85,5. Hasil spektrum UV-Vis pada bercak tersebut diperoleh serapan pada 340 nm (pita I) dan 240 nm (pita II). Sedangkan spektrum infra merah menunjukan adanya sinyal pada 3363 cm-1 (O-H ulur), 1727 cm-1 (C=O), 1459 cm-1 (cincin aromatik) dan 1060 cm-1 kuat (C-O). Dengan demikian, dapat disimpulkan bahwa fraksi etil asetat hidrolisat ekstrak etanol daun Cordia mengandung senyawa flavonoid yang mirip dengan kelompok kalkon.
Anatomi Jaringan, Identifikasi Mikroskopis, serta Kadar Polifenol Ekstrak Etanol Daun dari Tiga Jenis Jambu Genus Syzygium Hikmawanti, Ni Putu Ermi; Yumita, Agustin; Hanani, Endang; Faradisa, Shafira; Az-Zahra, Siti Fatimah; Ashfiya , Shafna Raudlatul
MPI (Media Pharmaceutica Indonesiana) Vol. 5 No. 1 (2023): JUNE
Publisher : Fakultas Farmasi, Universitas Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24123/mpi.v5i1.5311

Abstract

Tiga spesies dari genus Syzygium, seperti jambu air (Syzygium aqueum (Burm.f.) Alston), jambu bol (Syzygium malaccense (L.) Merr. & L.M. Perry), dan jambu semarang (Syzygium samarangense (Blume) Merr. & L. M. Perry), telah dimanfaatkan daunnya dalam pengobatan tradisional karena kandungan polifenolnya. Penelitian ini bertujuan untuk mempelajari anatomi jaringan, mikroskopis, kadar senyawa fenol, flavonoid, dan tanin ekstrak etanol daun dari tiga jenis jambu tersebut. Daun jambu biji (Psidium guajava) digunakan sebagai pembanding. Anatomi jaringan daun dan identifikasi mikroskopis dilakukan menggunakan mikroskop. Penentuan kadar senyawa pada ekstrak etanol 70% ditentukan dengan metode kolorimetri yang absorbansinya diukur pada spektrofotometer UV- Vis. Anatomi jaringan daun dan fragmen pengenal secara mikroskopis ada kemiripan pada ketiga jenis daun jambu genus Syzygium. Secara statistik, ada perbedaan signifikan antara kadar fenol, flavonoid, dan tanin pada ekstrak etanol 70% daun jambu air, daun jambu bol, dan daun jambu semarang dibandingkan dengan ekstrak etanol 70% daun jambu biji. Daun jambu air merupakan spesiesterpilih dari genus Syzygium yang diuji pada penelitian ini dengan kandungan polifenol yang tinggi. Leaves of three guava species of the genus Syzygium, such as water apple/jambu air (Syzygium aqueum (Burm.f.) Alston), malay apple/jambu bol (Syzygium malaccense (L.) Merr. & L.M. Perry), and wax apple/jambu Semarang (Syzygium samarangense (Blume) Merr. & L. M. Perry), have been used in traditional medicine because of its polyphenol content. This study aims to investigate the anatomy of leaf tissues, powder microscopical characteristic, and total phenolic, flavonoids, and tannins content in the ethanol extract of the leaves of the three types of selected guava species of the genus Syzygium. Guava leaves (Psidium guajava) were used as a comparison. Leaf tissue anatomy and microscopic identification were carried out using a microscope. Determination of the polyphenol content in 70% ethanol extract was determined by the colorimetric method in which the absorbance was measured on a UV-Vis spectrophotometer. Leaf tissue anatomy and microscopic recognition fragments are similar in the three types of Syzygium guava leaves. Statistically, there were significant differences between the total phenols, flavonoids, and tannins content in the 70% ethanol extract of water apple, Malay apple, and wax apple compared to the 70% ethanol extract of guava leaves. Water apple leaves are selectedspecies from the genus Syzygium tested in this study with high polyphenol content.
SOSIALISASI BAHAYA BAHAN KIMIA OBAT (BKO) DALAM JAMU DAN PELATIHAN MEMBUAT SEDUHAN HERBAL Hikmawanti, Ni Putu Ermi; Fatmawati, Sofia; Wiyati, Tuti
JURNAL PENGABDIAN FARMASI DAN SAINS Vol. 3 No. 1 (2024): Oktober 2024
Publisher : Jurusan Farmasi FMIPA Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jpsf.2024.v3.i1.17399

Abstract

Jamu is a traditional medicine that is still popular with Indonesian people. Jamu consists of herbs or medicinal plants that are efficacious for preventing disease and maintaining body health. Generally, herbal medicine can be prepared by the community themselves. However, nowadays, herbal medicine has developed a lot and is packaged in the form of products that are ready to be consumed. Unfortunately, several herbal medicine products were found to contain prohibited medicinal chemicals (BKO). The community needs socialization of the dangers of BKO and training in making herbal infusions that are safe, easy and healthy for the body. Women from PKK RT 06 RW 05 Malaka Sari are the targets for this activity. The success achievements of the activities were evaluated with a pre-post-test by filling out a questionnaire. In the future, knowledge regarding the safe selection and method of consuming herbal medicine can be applied in the family to maintain body health and preserve the consumption of herbal medicine as Indonesia's cultural heritage.
KANDUNGAN PIPERIN DALAM EKSTRAK BUAH LADA HITAM DAN BUAH LADA PUTIH (Piper nigrum L.) YANG DIEKSTRAKSI DENGAN VARIASI KONSENTRASI ETANOL MENGGUNAKAN METODE KLT-DENSITOMETRI Hikmawanti, Ni Putu Ermi; Hariyanti, Hariyanti; Aulia, Cahya; Viransa, Vesya Putri
Media Farmasi: Jurnal Ilmu Farmasi Vol. 13 No. 2: September 2016
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v13i2.7769

Abstract

Kualitas ekstrak buah lada (Piper nigrum L.) dipengaruhi oleh komponen dan kadar senyawa didalamnya. Piperin merupakan senyawa alkaloid utama dalam buah lada.  Banyaknya piperin yang larut selama proses ekstraksi dipengaruhi oleh jenis pelarut yang digunakan. Penelitian ini didesain untuk mengetahui kadar piperin dalam ekstrak buah lada hitam dan lada putih yang diekstraksi dengan variasi konsentrasi etanol. Ekstraksi buah lada dilakukan dengan metode ekstraksi sokhlet menggunakan variasi konsentrasi etanol (60%, 70% dan 96%) dan kemudian dilanjutkan dengan teknik ekstraksi asam-basa untuk mendapatkan ekstrak alkaloidnya. Ekstrak alkaloid masing-masing dianalisis pada plat KLT silika gel 60 F254 sebagai fase diam dan campuran n-heksana:etil asetat (1:1) sebagai fase gerak. Kadar piperin ditetapkan menggunakan metode KLT-densitometri pada panjang gelombang 254 nm. Hasil menunjukkan bahwa kadar piperin tertinggi diperoleh dari ekstrak buah lada hitam menggunakan pelarut etanol 60% sebagai pelarut pengekstraksi dengan kadar 52,81±4,66 (%b/v) terhadap ekstrak alkaloidnya. Kadar piperin tertinggi diperoleh dari ekstrak buah lada putih menggunakan pelarut etanol dengan konsentrasi 96% sebagai pelarut pengekstraksi dengan kadar 38,72±8,28 (%b/v) terhadap ekstrak alkaloidnya.
Kombinasi Ekstrak Herba Andrographis Paniculata (Burm f.) Nees dan Daun Pandanus Amaryllifolius Roxb. Sebagai Antihiperglikemia Hikmawanti, Ni Putu Ermi; Sunaryo, Hadi; Prasetyo, Rachmad Eka
Media Farmasi: Jurnal Ilmu Farmasi Vol. 15 No. 1: Maret 2018
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v15i1.9696

Abstract

Herba Andrographis paniculata (Burm f.) Nees atau sambiloto dan daun Pandanus amaryllifolius (Burm f.) Nees atau pandan wangi telah diketahui khasiatnya sebagai antihiperglikemia. Penelitian bertujuan untuk mengoptimasi kombinasi ekstrak etanol 70% herba sambiloto dan daun pandan wangi sebagai antihiperglikemia pada tikus jantan galur Sprague Dawley yang diinduksi aloksan. Hewan uji dibagi menjadi 7 kelompok perlakuan, masing-masing kelompok terdiri dari 4 ekor tikus. Kelompok I adalah kelompok tanpa perlakuan; kelompok II mendapatkan glibenklamid dosis 0,26 mg/Kg BB; kelompok III mendapatkan ekstrak herba sambiloto tunggal dosis 1000 mg/Kg BB; kelompok IV mendapatkan ekstrak daun pandan wangi tunggal dosis 600 mg/Kg BB; kelompok V, VI, dan VII masing-masing mendapatkan kombinasi ekstrak herba sambiloto dan daun pandan wangi dosis berturut-turut 1000:300, 500:300, dan 500:600 mg/Kg BB. Pemeriksaan kadar gula darah menggunakan sampel serum darah tikus yang diukur dengan metode GOD-PAP dan dibaca dengan spektrofotometer klinikal mikrolab 300. Preparat jaringan pankreas diamati menggunakan mikroskop dengan perbesaran 40x untuk melihat ada tidaknya vacuolation dan nekrosis pada sel pulau Langerhans pankreas. Data persentase penurunan kadar gula darah tikus dianalisis menggunakan ANOVA satu arah dan dilanjutkan dengan uji Tukey. Gambaran histopatologi pankreas dianalisis secara deskriptif. Hasil penelitian menunjukkan bahwa kelompok yang mendapatkan kombinasi ekstrak herba sambiloto dan daun pandan wangi (500:300 mg/Kg BB) merupakan kelompok kombinasi yang lebih baik dari kelompok ekstrak tunggalnya (p<0,05) dan sebanding dengan kelompok kontrol positif glibenklamid (p>0,05) dalam menurunkan kadar gula darah. Semua kelompok kombinasi ekstrak mampu memberikan perbaikan sel pulau Langerhans pankreas tikus. 
Piperine Levels in Java Chili and Black Fruits Extracts from Regions with Different Altitude Hikmawanti, Ni Putu Ermi; Hanani, Endang; Maharani, Shintia; Putri, Ajeng Istiningtyas Wahyudi
Jurnal Jamu Indonesia Vol. 6 No. 1 (2021): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v6i1.176

Abstract

Piper retrofractum Vahl. (java chili or cabe jawa) and Piper nigrum L. (black pepper or lada hitam) are parts of the Piperaceae. One of the chemical constituents found in the fruit of the two plants is piperine, which has properties as antimicrobial, antidiabetic, anti-inflammatory, anticancer etc. This study aims to determine the piperine levels contained in 95% ethanol extract of java chili and black pepper fruits from regions with different altitude using UV-Visible spectrophotometer. Each sample were extracted by maceration method using 95% ethanol. Qualitative identification of piperine was carried out using thin layer chromatography (TLC). Determination of piperine levels was carried out with UV-Visible spectrophotometer at maximum wavelength of 253.8 nm. The results showed that the levels of piperine contained in the 95% ethanol extract of java chili fruit from low altitude (Lampung), medium altitude (Madura) and high altitude (Bogor) are 1.54&plusmn;0.02%; 1.44&plusmn;0.02%; and 1.41&plusmn;0.02% (w/v), respectively. Whereas the levels of piperine contained in the 95% ethanol extract of black pepper fruit from low altitude (East Luwu), medium altitude (Central Lampung) and high altitude (Bogor) are 5.63&plusmn;0.14%; 5.38&plusmn;0.05%; and 4.87&plusmn;0.09% (w/v), respectively.
Co-Authors Abdul Mun'im Agustin Yumita Agustin Yumita Agustin Yumita Agustin Yumita Ajeng Istiningtyas Wahyudi Putri Amalia, Halisa Annisa, Ayyoehan Tiara Arif Fauzan, Muhammad Arry Yanuar Ashfiya , Shafna Raudlatul Aulia, Cahya Aulia, Cahya Ayyoehan Tiara Annisa Az-zahra, Siti Fatimah Cahya Aulia Cahyani, Siti Rosidah Cahyaningrum, Niken Chandra Adam Lesmana Chatarina Umbul Wahyuni Daniek Viviandhari Endang Hanani Endang Hanani Fadlina Chany Saputri Faradisa, Shafira Fatmawati, Sofia Fujianti Hadi Sunaryo Hadi Sunaryo Hariyanti Hariyanti Hariyanti, Hayati Hayati Hayati Hayati Jihan Esa Siregar Lusiana Lusiana Maharani, Shintia Maifitrianti Maifitrianti Maifitrianti Maifitrianti, Maifitrianti Mardiyanti, Rini Muhammad Rafiq Mun'im, Abdul Nora Wulandari Novia Delita Numlil Khaira Rusdi, Numlil Khaira Nurhasna, Nurhasna Nurhasnah Nurhasnah Nurhasnah Nurhidayah, Sahera Nurkamalia, Prasetyo, Rachmad Eka Prasetyo, Rachmad Eka Putri, Ajeng Istiningtyas Wahyudi Putri, Meira Amalia Rachmad Eka Prasetyo Ratih Asmana Ningrum Shintia Maharani Silvy Yulida Sofia Fatmawati Tuti Wiyati Tuti Wiyati Tuti Wiyati Ulfah, Yuanita Sofiana Vesya Putri Viransa Vindianita . Viransa, Vesya Putri Viransa, Vesya Putri Wiyati, Tuti Wiyati, Tuti Yeni Andriyani Yeni Andriyani Yuanita Sofiana Ulfah Yumita, Agustin Zainal Arifin