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All Journal HAYATI Journal of Biosciences Jurnal Tumbuhan Obat Indonesia Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Indonesian Journal of Pharmaceutical Science and Technology Indonesian Journal of Tropical and Infectious Disease Biology, Medicine, & Natural Product Chemistry MPI (Media Pharmaceutica Indonesiana) Jurnal Wiyata : Penelitian Sains dan Kesehatan As-syifaa Jurnal Farmasi Jurnal SOLMA Jurnal Ilmu Kefarmasian Indonesia Jurnal Jamu Indonesia BERNAS: Jurnal Pengabdian Kepada Masyarakat J.Abdimas: Community Health Society: Jurnal Pengabdian Masyarakat Pharmaceutical Sciences and Research (PSR) Jurnal Pengabdian Masyarakat Bangsa Borneo Journal of Pharmacy Jurnal Pengabdian Farmasi dan Sains Indonesian Journal of Jamu
Ni Putu Ermi Hikmawanti
Departemen Biologi Farmasi, Fakultas Farmasi Dan Sains, Universitas Muhammadiyah Prof. DR. HAMKA, DKI Jakarta 13460, Indonesia
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Drying's Impact on Antioxidant Compound Levels in Curcuma heyneana Valeton & Zijp. (Temu Giring) Agustin Yumita; Ni Putu Ermi Hikmawanti; Heksa Mu’adah; Endang Hanani
Biology, Medicine, & Natural Product Chemistry Vol 15, No 1 (2026)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2026.151.631-637

Abstract

One plant in the genus Curcuma that exhibits potential as a natural antioxidant is Curcuma heyneana Valeton & Zijp., commonly known as temu giring. This species contains phenolic and flavonoid compounds. The objective of this research was to quantify the phenolic and flavonoid content, as well as assess the antioxidant activity of fresh and dried rhizomes. The extraction methods employed were infusion and decoction. Phenolic content was measured using the colorimetric method with the Folin-Ciocalteu reagent, while flavonoid content was determined using the AlCl3 reagent. Antioxidant activity was evaluated using the FRAP method. The highest phenolic content was observed in the oven-dried decoction extract (EDOD) at 6.258 mg GAE/g, and the highest total flavonoid content was also found in this EDOD at 2.899 mg QE/g. The most potent antioxidant activity among the test samples was exhibited by this EDOD, with a value of 12.064 mol FeEAC/g. The results indicate that higher drying temperatures correlate with increased phenolic and flavonoid levels in the temu giring rhizome, consequently influencing the antioxidant activity in the sample.
Peningkatan Kompetensi Peserta Didik dalam Pengembangan Produk Kosmetik Berkelanjutan melalui Program Edukasi Terintegrasi tentang Aromaterapi Alami Agustin Yumita; Pramulani Mulya Lestari; Ni Putu Ermi Hikmawanti; Novia Delita
Jurnal Pengabdian Masyarakat Bangsa Vol. 4 No. 3 (2026): Mei
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v4i3.4330

Abstract

Pemahaman remaja mengenai penggunaan aromaterapi dalam kosmetik masih terbatas, khususnya terkait keamanan dan cara formulasi. Kegiatan ini bertujuan meningkatkan pengetahuan peserta didik melalui edukasi terintegrasi tentang pemanfaatan minyak atsiri dalam produk kosmetik sederhana. Metode yang digunakan meliputi penyuluhan interaktif, pengenalan bahan aromaterapi, serta evaluasi melalui pre-test dan post-test. Sebanyak 26 peserta mengikuti kegiatan ini. Hasil menunjukkan adanya peningkatan pemahaman yang jelas, ditandai dengan kenaikan skor dari sebelum ke sesudah edukasi pada seluruh peserta. Materi mencakup konsep dasar aromaterapi, manfaat, sumber bahan, serta prinsip keamanan penggunaan dalam kosmetik. Pendekatan yang menggabungkan penjelasan dan observasi langsung membantu peserta memahami materi dengan lebih baik. Kegiatan ini efektif dalam meningkatkan pengetahuan peserta serta mendukung pemanfaatan bahan alam secara aman dan tepat dalam pengembangan kosmetik sederhana.  
Peningkatan Pengetahuan Pangan yang Aman dan Sehat serta Bantuan Sosial untuk Berbuka Puasa Selama Ramadhan Rizky Arcinthya Rachmania; Ni Putu Ermi Hikmawanti; Tuti Wiyati
Jurnal Pengabdian Masyarakat Bangsa Vol. 4 No. 4 (2026): Juni
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v4i4.4426

Abstract

Selama bulan Ramadhan seringkali muncul banyak pedagang kaki lima yang menjual makanan dan minuman untuk berbuka puasa. Kegiatan ini bertujuan untuk meningkatkan pengetahuan warga Malaka Sari Jakarta Timur mengenai cara memilih pangan aman dari pedagang kaki lima selama bulan Ramadhan serta meringankan kaum lansia atau dhuafa yang tidak memiliki penghasilan. Pelaksanaan pengabdian pada Masyarakat ini dilakukan dengan pemberian informasi dan beberapa saran untuk memilih makanan dan minuman yang aman dari pedagang kaki lima serta membagikan paket bantuan sosial berupa bahan makanan sehat. Dengan adanya kegiatan ini, diharapkan pengetahuan yang diperoleh dapat diterapkan oleh seluruh warga kepada keluarganya agar tetap sehat dan sejahtera selama menjalankan ibadah puasa Ramadhan. Sebelumnya, peserta diminta untuk mengisi kuesioner pre-kegiatan. Setelah flyer diserahkan, peserta diminta mengisi kuesioner post-kegiatan. Berdasarkan analisis statistik, diperoleh hasil bahwa terjadi peningkatan pengetahuan tentang cara atau tips memilih pangan berbuka puasa yang aman dan bantuan sosial bermanfaat untuk mitra.
The Microelement Analysis, Physicochemical Properties of Ethyl Acetate Fraction of Kaempferia galanga L. and Its Lipid Peroxidation Inhibitory Bariroh, Tahyatul; Supandi, Supandi; Hikmawanti, Ni Putu Ermi; Siska, Siska
MPI (Media Pharmaceutica Indonesiana) Vol. 8 No. 1 (2026): JUNE
Publisher : Fakultas Farmasi, Universitas Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24123/mpi.v8i1.7865

Abstract

A previous study reported that Kaempferia galanga L. (K. galanga) has anti-inflammatory and antioxidant activity. However, the research about how Kaemferia galanga L. inhibits lipid peroxidation (LPOI) has been limited. This study aimed to determine the physicochemical properties of the ethyl acetate fraction of K. galanga (EAFK) and its lipid peroxidation inhibitory activity. The anatomical structure of the rhizome was observed using a light microscope and scanning electron microscopy (SEM). Microelement analysis was determined by SEM-Energy Dispersive X-Ray Spectroscopy (SEM-EDX) mapping. The 70% ethanol extract of K. galanga was fractionated by a liquid-liquid technique using ethyl acetate. Phytochemical, the total phenolic and flavonoid levels, ethyl-p-methoxycinnamate (EPMC) as a marker compound, the specific and non-specific parameters of the fraction were determined. The antioxidant activity was evaluated using DPPH and LPOI assays. The results showed that the rhizome of K. galanga has oil cells, and the powder contains microelements. The EPMC level in the EAFK was 0.66 % (w/w). At concentrations of 4000 ppm and 625 ppm, the EAFK could inhibit 15.90%±0.35 of DPPH free radical scavenging and 17.43%±6.52 of lipid peroxidation, respectively. Based on these findings, K. galanga contains microelements, EPMC, and the EAFK has an antioxidant effect via inhibiting lipid peroxidation and antiradical activity.
KADAR FENOLIK TOTAL DAN SITOTOKSISITAS EKSTRAK GALING (Causonis trifolia (L.)): STUDI VARIASI KONSENTRASI PELARUT DAN METODE EKSTRAKSI Ni Putu Ermi Hikmawanti; Sofia Sofia; Muhammad Rafiq; Reni Anggraeni
Jurnal Wiyata Penelitian Sains dan Kesehatan Vol 13 No 1 (2026)
Publisher : LP2M IIK (Lembaga Penelitian dan Pengabdian Masyarakat Institut Ilmu Kesehatan) Bhakti Wiy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56710/wiyata.v13i1.1085

Abstract

Latar belakang: Tanaman galing (Causonis trifolia (L.) Mabb. & J.Wen.) merupakan bagian dari Vitaceae. Galing mengandung senyawa fenolik yang berperan sebagai antioksidan dan antikanker. Ekstraksi senyawa ini sangat dipengaruhi oleh pemilihan pelarut dan metode ekstraksi. Tujuan: mengetahui pengaruh variasi konsentrasi etanol sebagai pelarut ekstraksi dan metode ekstraksi terhadap perolehan kadar fenolik total dan efek sitotoksisitas ekstrak yang dihasilkan. Metode: Simplisia yang digunakan adalah seluruh bagian tanaman galing. Konsentrasi etanol yang digunakan adalah 50, 70, dan 96%. Variasi metode ekstraksi yang digunakan adalah maserasi, refluks, dan ultrasonikasi. Penentuan kadar fenolik menggunakan teknik kolorimetri dengan asam galat sebagai standar. Pengujian sitotoksisitas dilakukan dengan metode Brine Shrimp Lethality Test (BSLT) terhadap Artemia salina. Tiap sampel ekstrak yang diujikan pada A. salina disiapkan pada rentang konsentrasi 1-5 mg/mL. Hasil: Etanol 70% merupakan pelarut yang paling tinggi dalam mengekstraksi fenolik pada tanaman galing. Sementara itu, kadar fenolik ekstrak etanol 70% galing paling tinggi dihasilkan dari metode ekstraksi refluks (867,21 mgGAE/g ekstrak). Ekstrak etanol 70% galing tersebut menunjukkan efek sitotoksisitas dengan nilai IC50 sebesar 2,56 mg/mL. Simpulan dan saran: Variasi konsentrasi pelarut etanol dan metode ekstraksi berpengaruh terhadap kadar fenolik total dan nilai sitotoksisitas dari ekstrak galing. Komponen fenolik tanaman galing berperan dalam efek sitotoksisitas ekstraknya.
Antihyperlipidemic and antioxidant activities of “mimicking honey” extract from Basil (Ocimum americanum L.) stem waste Azza Indrijati Nompo; Afifah Putri Zahrah; Nasywa Fadhiya Pamuji; Nurul Aulia Putri; Abdi Fathir Alfarizki; Lusi Putri Dwita; Ni Putu Ermi Hikmawanti
JURNAL ILMU KEFARMASIAN INDONESIA Vol. 24 No. 2 (2026): JIFI In Press
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v24i2.2023

Abstract

Basil (Ocimum americanum L.) has broad pharmacological activity related to its phenolic content. This compound is a natural antioxidant, which also plays a role in reducing lipid profiles. Phenolics can be extracted with a “mimicking honey” (one type of the natural deep eutectic solvents, NADES) as an alternative solvent, that is greener than common volatile organic solvents, such as ethanol. This study aimed to evaluate the antihyperlipidemic and antioxidant activities of basil stem waste extract prepared using a mimicking honey solvent formulated from water, sucrose, glucose, and fructose. Extraction was conducted via ultrasonic-assisted methods. An in vivo test was performed on male Wistar rats induced with hyperlipidemia using quail egg yolk and propylthiouracil. The animals were divided into eight groups: normal control (no treatment), positive control (atorvastatin), mimicking honey solvent (MHS), honey solvent (HS), water solvent (WS), basil stem mimicking honey extract (MHE), basil stem honey extract (HE), and basil stem water extract (WE). Measured parameters included total cholesterol (TC), triglycerides (TG), and malondialdehyde (MDA) levels. Results indicated that the MHE group showed significantly different levels of TC (123.00 ± 12.85 mg/dL; P <0.01), TG (85.25 ± 22.29 mg/dL; P <0.001), and MDA (8.10 ± 0.20 nmol/mL; P <0.0001) compared to the WS group. These findings suggest that synthetic honey solvent is an effective "green solvent" for extracting bioactive compounds from basil stem, offering potential antihyperlipidemic and antioxidant benefits. 
Co-Authors Abdi Fathir Alfarizki Abdul Mun'im Afifah Putri Zahrah Agustin Yumita Agustin Yumita Ajeng Istiningtyas Wahyudi Putri Amalia, Halisa Anggitha Prameswari Putri Annisa, Ayyoehan Tiara Arif Fauzan, Muhammad Arry Yanuar Ashfiya , Shafna Raudlatul Aulia, Cahya Aulia, Cahya Ayyoehan Tiara Annisa Az-zahra, Siti Fatimah Azza Indrijati Nompo Bambang Prajogo Eko Wardojo Cahya Aulia Cahyani, Siti Rosidah Cahyaningrum, Niken Chandra Adam Lesmana Chatarina Umbul Wahyuni Daniek Viviandhari Dwitiyanti Dwitiyanti Endang Hanani Endang Hanani Endang Hanani Fadlina Chany Saputri Faradisa, Shafira Fatmawati, Sofia Fujianti Hadi Sunaryo Hadi Sunaryo Hariyanti Hariyanti Hayati Hayati Hayati Hayati Heksa Mu’adah Jihan Esa Siregar Lestari, Pramulani Mulya Lusi Putri Dwita Lusiana Lusiana Maharani, Shintia Maifitrianti Maifitrianti Maifitrianti Maifitrianti, Maifitrianti Mardiyanti, Rini Muhammad Rafiq Muhammad Rafiq Mun'im, Abdul Nasywa Fadhiya Pamuji Nora Wulandari Novella Chulsum Novia Delita Novia Delita Numlil Khaira Rusdi, Numlil Khaira Nurhasna, Nurhasna Nurhasnah Nurhasnah Nurhasnah Nurhidayah, Sahera Nurkamalia, Nurul Aulia Putri Prasetyo, Rachmad Eka Prasetyo, Rachmad Eka Prihartini Widiyanti Putri, Ajeng Istiningtyas Wahyudi Putri, Meira Amalia Rachmad Eka Prasetyo Ratih Asmana Ningrum Reni Anggraeni Rizky Arcinthya Rachmania Shintia Maharani Silvy Yulida Siska Siska Sofia Fatmawati Sofia Sofia Supandi Tahyatul Bariroh Tuti Wiyati Tuti Wiyati Tuti Wiyati Tuti Wiyati Ulfah, Yuanita Sofiana Vesya Putri Viransa Vindianita . Viransa, Vesya Putri Viransa, Vesya Putri Wiyati, Tuti Wiyati, Tuti Yeni Andriyani Yeni Andriyani Yuanita Sofiana Ulfah Zainal Arifin