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All Journal HAYATI Journal of Biosciences Jurnal Farmasi Udayana Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Indonesian Journal of Pharmaceutical Science and Technology MPI (Media Pharmaceutica Indonesiana) As-syifaa Jurnal Farmasi Jurnal SOLMA Jurnal Jamu Indonesia BERNAS: Jurnal Pengabdian Kepada Masyarakat J.Abdimas: Community Health Jurnal Mitra Masyarakat (JMM) Society: Jurnal Pengabdian Masyarakat Pharmaceutical Sciences and Research (PSR) Borneo Journal of Pharmacy Jurnal Pengabdian Farmasi dan Sains Indonesian Journal of Jamu
Ni Putu Ermi Hikmawanti
Departemen Biologi Farmasi, Fakultas Farmasi Dan Sains, Universitas Muhammadiyah Prof. DR. HAMKA, DKI Jakarta 13460, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Total Flavonoid Content in Hydro-ethanolic Extract of Sauropus androgynus (L.) Merr Leaves from Three Regions with Different Altitude Ni Putu Ermi Hikmawanti; Hayati; Yeni Andriyani
Jurnal Jamu Indonesia Vol. 6 No. 2 (2021): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v6i2.195

Abstract

Sauropus androgynus (L.) Merr (Phyllanthaceae), also known as katuk in Indonesia, is a plant that grows in tropical climates. The study aimed to determine the total flavonoid levels of hydroethanolic extract of katuk leaves from three regions with different altitudes. Dried katuk leaves were macerated using hydroethanolic (the mixture of ethanol:H2O (7:3, v/v)) as solvent extraction at room temperature. Determination of flavonoid levels was carried out by the colorimetry method using AlCl3 reagent. Quercetin was used as a reference. A UV-Visible spectrophotometer measured the absorbance at the maximum wavelength of 434.50 nm. The total flavonoids level of hydroethanolic extract of katuk leaves from a different region with low-altitude (Bogor), medium-altitude (Sleman), and high-altitude (Bandung) are 8.56±0.63 mgQE/g, 4.67±0.30 mgQE/g, and 9.72±0.24 mgQE/g, respectively. Thus, it can be concluded that there are differences in total flavonoid levels of hydroethanolic extract of katuk leaves from three regions with different altitudes.
Antioxidant Polyphenolics Extraction Techniques from Beluntas Leaves using Choline Chloride-Urea: Comparative Study with 70%-Ethanol Hikmawanti, Ni Putu Ermi; Yumita, Agustin; Amalia, Halisa; Cahyani, Siti Rosidah; Putri, Meira Amalia; Mun'im, Abdul
MPI (Media Pharmaceutica Indonesiana) Vol. 7 No. 2 (2025): DECEMBER
Publisher : Fakultas Farmasi, Universitas Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24123/mpi.v7i2.7627

Abstract

Pluchea indica L. (Less), known as Indian camphorweed (common name) or Beluntas (Indonesia), is an antioxidant polyphenol-rich plant. In our previous studies, choline chloride-urea (CCU) at a molar ratio of 1:2 was one type of natural deep eutectic solvents (NADES) in the extraction of P. indica leaves (PIL) polyphenolics. The present study aims to evaluate the comparison of total phenolics (TPC) and flavonoids content (TFC) and antioxidant activity of CCU (1:2) extract of PIL obtained from ultrasonic-assisted extraction (UAE) and magnetic stirrer-assisted extraction (MSAE). Ethanol was used as a comparison to conventional extraction solvents. Determination of TPC and TFC was carried out using colorimetric with a microplate reader, while the antioxidant activity test was carried out using the ferric thiocyanate (FTC) method. The UAE is more effective in terms of PIL flavonoid extraction using CCU compared to MSAE, while PIL phenolic extraction with CCU is more effective with MSAE. CCU extract of PIL from extraction with MSAE at a concentration of 1.56% has an antioxidant capacity equivalent to 500 ppm ascorbic acid in inhibiting lipid peroxidation by about 70%. Thus, CCU combined with the MSAE can be recommended in further development of phenolic antioxidants extraction from PIL.
Co-Authors Abdul Mun'im Agustin Yumita Agustin Yumita Agustin Yumita Agustin Yumita Ajeng Istiningtyas Wahyudi Putri Amalia, Halisa Annisa, Ayyoehan Tiara Arif Fauzan, Muhammad Arry Yanuar Ashfiya , Shafna Raudlatul Aulia, Cahya Aulia, Cahya Ayyoehan Tiara Annisa Az-zahra, Siti Fatimah Cahya Aulia Cahyani, Siti Rosidah Cahyaningrum, Niken Chandra Adam Lesmana Chatarina Umbul Wahyuni Daniek Viviandhari Endang Hanani Endang Hanani Fadlina Chany Saputri Faradisa, Shafira Fatmawati, Sofia Fujianti Hadi Sunaryo Hadi Sunaryo Hariyanti Hariyanti Hariyanti, Hayati Hayati Hayati Hayati Jihan Esa Siregar Lusiana Lusiana Maharani, Shintia Maifitrianti Maifitrianti Maifitrianti Maifitrianti, Maifitrianti Mardiyanti, Rini Muhammad Rafiq Mun'im, Abdul Nora Wulandari Novia Delita Numlil Khaira Rusdi, Numlil Khaira Nurhasna, Nurhasna Nurhasnah Nurhasnah Nurhasnah Nurhidayah, Sahera Nurkamalia, Prasetyo, Rachmad Eka Prasetyo, Rachmad Eka Putri, Ajeng Istiningtyas Wahyudi Putri, Meira Amalia Rachmad Eka Prasetyo Ratih Asmana Ningrum Shintia Maharani Silvy Yulida Sofia Fatmawati Tuti Wiyati Tuti Wiyati Tuti Wiyati Ulfah, Yuanita Sofiana Vesya Putri Viransa Vindianita . Viransa, Vesya Putri Viransa, Vesya Putri Wiyati, Tuti Wiyati, Tuti Yeni Andriyani Yeni Andriyani Yuanita Sofiana Ulfah Yumita, Agustin Zainal Arifin