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Analisis Faktor Faktor Risiko Anemia pada Anak di Rumah Sakit Umum Daerah Wangaya Bali Suriadi, Regina; Mustika, Putu Pradnyanita; Wielim, Edbert; Cynthia, Cynthia; Suryawan, I Wayan Bikin
Sari Pediatri Vol 27, No 1 (2025)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp27.1.2025.32-7

Abstract

Latar belakang. Anemia merupakan kondisi yang sering ditemukan pada anak. Anemia memiliki dampak yang besar bagi pertumbuhan, perkembangan, morbiditas dan mortalitas anak, sehingga penting untuk mencegah dan menangani anemia pada anak sejak dini. Tujuan. Penelitian ini bertujuan mengetahui hubungan kejadian anemia dan faktor-faktor determinannya pada pasien anak.Metode. Penelitian ini adalah penelitian cross-sectional analitik melibatkan pada pasien anak dengan anemia yang datang ke Rumah Sakit Umum Daerah Wangaya, Bali selama periode Januari 2023 hingga jumlah sampel terpenuhi. Berdasarkan jumlah sampel minimal untuk penelitian cross-sectional dibutuhkan minimal 76 sampel. Kriteria inklusi adalah pasien anak berusia 1 bulan -18 tahun yang terdiagnosis anemia. Pasien dengan catatan medis yang tidak lengkap dikeluarkan dari penelitianHasil. Sebanyak 76 pasien anak dengan anemia diikutsertakan dalam penelitian ini. Rata-rata kadar Hb 12-20% lebih rendah pada kelompok dengan berat badan lahir rendah, usia ibu, lama pemberian ASI, stunted, gizi kurang, dan riwayat gastroenteritis, hasil ini juga bermakna secara statistik. Analisis multivariat menunjukkan faktor yang memiliki hubungan paling kuat terhadap kadar Hb anak adalah gizi kurang (koefisien ?: 0,283).Kesimpulan. Terdapat hubungan antara faktor anak (BBLR, stunted, gizi kurang, riwayat gastroenteritis) dan faktor ibu (usia ibu, lama pemberian ASI) terhadap kejadian anemia pada anak.
Associations between plasma beta amyloid and cognitive decline: A systematic review and meta-analysis Cynthia, Cynthia; Nugraha, Jusak; Hamdan, Muhammad; Dharma, Rahajuningsih; Lumempouw, Silvia F.
Narra J Vol. 5 No. 2 (2025): August 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i2.2268

Abstract

Alzheimer’s disease is a leading neurodegenerative disorder characterized by progressive cognitive decline. Early prediction is crucial for enabling timely interventions. Plasma amyloid β-peptides (Aβ), particularly the Aβ-42/Aβ-40 ratio, have been proposed as potential non-invasive biomarkers for cognitive decline and Alzheimer’s disease risk. However, conflicting findings and methodological variability have hindered consensus regarding their clinical utility. The aim of this study was to evaluate whether the plasma Aβ levels predict dementia, Alzheimer’s disease, and cognitive decline. Studies were eligible for inclusion if they measured at least one plasma Aβ species (Aβ-40, Aβ-42, or the Aβ-42/Aβ-40 ratio) and reported outcomes related to dementia, Alzheimer’s disease, or cognitive change. Only human studies published in peer-reviewed journals were included. A comprehensive search of six databases (PubMed, PMC, SSRN, Scopus, BioRxiv, and MedRxiv) was conducted up to December 1, 2024. Risk of bias was assessed using the ROBINS-E tool, and pooled hazard ratios (HRs) with 95% confidence intervals (CIs) were calculated using a random-effects meta-analysis. A total of 25 studies were included in the systematic review, with four contributing to the meta-analysis. Lower plasma Aβ-42/Aβ-40 ratio was not significantly associated with Alzheimer’s disease risk (pooled HR=0.8; 95%CI: 0.62–1.04), and substantial heterogeneity was observed (I²=70%, p=0.02). Individual studies varied in their findings: while some reported that lower Aβ-42/Aβ-40 ratio predicted increased Alzheimer’s disease risk, others found no association or even opposing trends. Methodological heterogeneity—including differences in sample handling, measurement techniques, and study designs—likely contributed to these inconsistencies. Overall, this review suggests that plasma Aβ-42/Aβ-40 ratio is not reliable predictors for the onset of Alzheimer’s disease or dementia. However, the substantial heterogeneity observed underscores the need for further research to clarify the potential of plasma Aβ as a preclinical biomarker.
Penyuluhan Perilaku Hidup Bersih Dan Sehat (PHBS) Pada Siswa Sekolah Luar Biasa (SLB-C) Karya Ibu Kota Palembang Juliyanda, Nugraha; Lestari, Peggy Ayu; Cynthia, Cynthia; Hayati, Thursina Vera; Hidayatullah, Muhammad Dwi; Khaeriyah, Muthia; Fitriani, Novi; Sari, Merry Afriliana; Astari, Dea Widya; Pradisa, Dea; Yuliantari, Devy; Apriliani, Ferenadia; Safithri, Vani; Idris, Haerawati
Community Services and Social Work Bulletin Vol 4, No 2 (2024): Community Services and Social Work Bulletin Volume 4 No. 2 2024
Publisher : Universitas Muhammadiyah Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31000/cswb.v4i2.12039

Abstract

Self-care activities are the ability to improve health by preventing disease and overcoming illness. Intellectually Disabled Children are expected to be able to carry out self-care independently, such as through implementing Clean and Healthy Living Behaviour (CHLB). This activity aims to provide understanding and CHLB skills, through the implementation of hand wash and dispose of waste. The activity method is counselling and practice using posters, power points and educational videos. The activity was held on November 9 2023 at the Karya Ibu Palembang C Special School (SLB-C). The targets of the activity are SLBC students, teachers and parents. The results of the activity showed that students were enthusiastic in participating in the activity. The activities are fully supported by teachers and parents, as can be seen from their presence. Extension activities have been proven to improve students' ability to carry out hand wash and dispose of waste. There are challenges faced in implementing activities, there are some students who lack focus in paying attention during counselling. CHLB for Intellectually Disabled Children is important to be carried out on an ongoing basis, the role of parents and teachers is needed to support the implementation of CHLB for Intellectually Disabled Children
Green Business and Creative Accounting: A Critical Review of Sustainability Reporting in the Era of Greenwashingin WATI, Ni Luh Anik Listya; MAULIDA, Shabrina; DEWI, Anak Agung Erna Listya; CYNTHIA, Cynthia
Loka: Journal Of Environmental Sciences Vol. 2 No. 3 (2025): Loka: Journal Of Environmental Sciences (July – September)
Publisher : PT. Keberlanjutan Strategis Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38142/ljes.v2i3.312

Abstract

Purpose:This study aims to examine the relationship between green business strategies and creative accounting practices in the context of sustainability reporting. In recent years, companies have been increasingly encouraged to project an environmentally friendly image in order to meet stakeholder demands and strengthen social legitimacy. However, companies often take advantage of the flexibility in financial reporting to construct sustainability narratives that do not fully reflect real conditions, a phenomenon known as greenwashing.Methodology:This study uses a systematic literature review approach to various national literature published in the last five years, to analyze the ambivalent role of creative accounting—as a strategic tool as well as a potential manipulative risk—in supporting or obscuring green business strategies.Findings:The results of the study show that the transparency of reporting largely determines the success of green business implementation, the integrity of management ethics, and the strengthening of sustainability reporting regulations in Indonesia.Implication:This research provides implications for the academic world, business practice, and public policy in encouraging more credible and accountable sustainability reporting.
KLASIFIKASI CITRA BATIK INDONESIA DAN MALAYSIA DENGAN METODE MODIFIED DISCRIMINANT ANALYSIS Cynthia, Cynthia; Hendryli, Janson; Herwindiati, Dyah Erny
Computatio : Journal of Computer Science and Information Systems Vol. 3 No. 1 (2019): COMPUTATIO : JOURNAL OF COMPUTER SCIENCE AND INFORMATION SYSTEMS
Publisher : Faculty of Information Technology, Universitas Tarumanagara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24912/computatio.v3i1.2973

Abstract

The application of Indonesian and Malaysian batik image classification using the Linear Discriminant Analysis (LDA) and Modified Discriminant Analysis (MDA) method is an introduction application that is used to classify images in the form of batik. Making this application uses the Java programming language to run feature retrieval methods, namely Color Histogram and Daubechies Wavelet and classification methods, namely LDA and MDA. Testing is done by blackbox testing method and confusion matrix. Tests are performed using color features, texture features, and a combination of training images and new test images. The best percentage test results are testing using color features, whereas with texture and the combination of both features get a slightly lower test percentage result.Aplikasi klasifikasi citra batik Indonesia dan Malaysia dengan metode Linear Discriminant Analysis (LDA) dan Modified Discriminant Analysis (MDA) merupakan aplikasi pengenalan yang digunakan untuk mengklasifikasi citra berupa batik. Pembuatan aplikasi ini menggunakan bahasa pemrograman Java untuk menjalankan metode pengambilan fitur yaitu Color Histogram dan Daubechies Wavelet dan metode pengklasifikasian yaitu LDA dan MDA. Pengujian dilakukan dengan metode blackbox testing dan matriks konfusi. Pengujian dilakukan dengan menggunakan fitur ciri warna, ciri tekstur, dan gabungan dari citra latih dan citra uji baru. Hasil persentase pengujian terbaik adalah pengujian dengan menggunakan ciri warna, sedangkan dengan ciri tekstur dan gabungan mendapatkan hasil persentase pengujian sedikit rendah.
PRODUKSI N-ASETILGLUKOSAMIN DARI KULIT UDANG MENGGUNAKAN KITINASE EKSTRASELULER DARI Providencia stuartii Halim, Yuniwaty; Cynthia, Cynthia; Hardoko, Hardoko; Handayani, Ratna
FaST - Jurnal Sains dan Teknologi (Journal of Science and Technology) Vol. 3 No. 2 (2020): MAY
Publisher : Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Cangkang udang tersusun dari kitin. Salah satu turunan kitin, yaitu glukosamin, biasanya terdapat dalam bentuk N-asetilglukosamin dan dapat diproduksi melalui fermentasi enzimatis terhadap kitin dengan menggunakan mikroorganisme kitinolitik. Salah satu bakteri kitinolitik adalah Providencia stuartii. Penelitian ini dilakukan untuk menentukan kondisi fermentasi optimum, yaitu pH, suhu, konsentrasi substrat, dan lama inkubasi, untuk memproduksi N-asetilglukosamin menggunakan kitinase ekstraseluler dari Providencia stuartii. pH yang digunakan dalam fermentasi adalah 3, 4, 5, 6, 7, 8, dan 9, sedangkan suhu yang digunakan adalah 30, 40, 50, 60, 70 and 80oC. Hasil penelitian menunjukkan bahwa kitinase ekstraseluler kasar memiliki aktivitas optimum pada pH 5 dan suhu 40oC, yaitu berturut-turut sebesar 3,23 ± 0,06 U/ml dan 3,42 ± 0,06 U/ml. Kitinase ekstraseluler semi murni memiliki aktivitas optimum pada pH 7 dan suhu 40oC, yaitu berturut-turut sebesar 4,74 ± 0,06 U/ml and 4,44 ± 0,06 U/ml. Selanjutnya, konsentrasi kitin sebagai substrat yang digunakan adalah sebesar 0,5; 1; 1,5; dan 2% dengan lama inkubasi 2, 4, 6, dan 24 jam. Konsentrasi N-asetilglukosamin tertinggi diperoleh setelah lama inkubasi 6 jam dengan konsentrasi substrat sebesar 1%, yaitu sebesar 933,89 ± 12,55 ppm menggunakan kitinase ekstraseluler kasar dan 1050,56 ± 12,54 ppm menggunakan kitinase ekstraseluler semi murni.