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All Journal HAYATI Journal of Biosciences JURNAL KIMIA SAINS DAN APLIKASI Jurnal Penelitian Sains (JPS) Matematika dan Sains Jurnal Penelitian Sains (JPS) IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) BERITA BIOLOGI JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA JPSriwijaya Science and Technology Indonesia Jurnal Penelitian Sains Indonesian Journal of Chemistry Indonesian Journal of Pure and Applied Chemistry IJEMS (Indonesian Journal of Environmental Management and Sustainability) Martabe : Jurnal Pengabdian Kepada Masyarakat Seminar Nasional Lahan Suboptimal Molekul: Jurnal Ilmiah Kimia Jurnal Ilmu Kefarmasian Indonesia BIOVALENTIA: Biological Research Journal Jurnal Ilmiah Bakti Farmasi SWARNA Jurnal Riset Rumpun Ilmu Kesehatan (JURRIKES) Karunia: Jurnal Hasil Pengabdian Masyarakat Indonesia Journal of World Future Medicine, Health and Nursing SWARNA: Jurnal Pengabdian Kepada Masyarakat Bumi: Jurnal Hasil Kegiatan Sosialisasi Pengabdian Kepada Masyarakat Journal of Biomedical and Techno Nanomaterials
Miksusanti Miksusanti
Department Of Chemistry, Faculty Of Mathematics And Natural Sciences, Sriwijaya University, Palembang, Indonesia
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Journal : JURNAL KIMIA SAINS DAN APLIKASI

 1 
Oliveramine: An Isolated Alkaloid from Fagraea fragrans (Tembesu) Bark Dasril Basir; Jefri Liasta; Annisa Amelia; Miksusanti Miksusanti; Susilawati Susilawati
Jurnal Kimia Sains dan Aplikasi Vol 25, No 7 (2022): Volume 25 Issue 7 Year 2022
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jksa.25.7.264-269

Abstract

This paper described the progress of phytochemical, especially alkaloids, work on Fagraea fragrans species (tembesu), Loganiaceae. A dimeric-pyridine alkaloid with molecular formula C20H20O4N2 has been successfully isolated from diethyl ether extracts from this plant’s barks. The alkaloid was explored from diethyl ether extracts using sulphuric acid (2%), then basified with ammonium hydroxide (25%) until the solution had a pH of 10.5. The later solution was extracted again with chloroform. The alkaloid residue was subjected to column chromatography and eluted with 10% acetone in chloroform. The chemical structure of the isolated dimeric-pyridine alkaloid was determined by LCMS/MS, 13C-NMR, and 1H-NMR spectroscopies. As a result, the isolated dimeric-pyridine alkaloid was closely similar to the oliveramine alkaloid, and this is also the first report about oliveramine from Fagraea fragrans (F. Fragrans).
Co-Authors Adi Supriyadi Adik Ahmadi Agus Syafriansyah Al Ainna Aldes Lesbani Almunadi T Panagan Almunady T. Panagan Amin, Rafiullah Andarmoyo, Sulistyo Annisa Amelia Asmak Asmak Azhar Kholiq Azhar Kholiq Bambang Ponco Bambang Ponco Bambang Ponco, Bambang Bambang Pontjo Priosoeryanto Betty S.L. J Betty Sri Laksmi J Betty Sri Laksmi Jenie Betty Sri Laksmi Jennie Budi Untari Budi Untari Darsil Basir Dasril Basir Dasril Basir Dasril Basir Dedi Rohendi Desnelli Desnelli Desnelli Desnelli Dian Dian Dian Dwita Maizur Dimas Nur Hidayat Dina Permata Wijaya Elfita Eli Sahara Eli Sahara Elsa Fitria Apriani Endang Setiyowati Endang Setiyowati Endri Junaidi Eviyanti Eviyanti Fachrijal Fachrijal Fanani, Muhammad Zainal Fatma Fitra Yosi Fitrya . Fitrya Fitrya Gatot T. Mulyadi Gatot Tri Mulyadi Gatot Trimulyadi Gatot Trimulyadi Rekso Getari Kasmiarti Harian Saputra Harmida Harmida Heni Yohandini Heni Yohandini K Herlina Herlina Herlina Herlina Hermansyah Hermansyah Hermansyah Hermansyah Hermansyah Hotdelina S Hotdelina S Ina Suci Pratiwi Indah Solihah Indah Solihah Ismed Ismed Jefri Liasta Jennie, Betty Sri Laksmi Juswardi Juswardi Kovalina, Yosi Maidelwita, Yani Meisji Liana Sari Muharni Muharni Muntasir, Muntasir Mutia Sari Wardana Nasir Rofiq Neza Rahayu Nike Marfinda Nirwan Syarif Nita Aminasih Nova Yuliasari Novian Sutami Novrikasari Novrikasari, Novrikasari NUNI GOFAR Nurul Huda Raza, Amir Razak, Faisal Rennie Puspa Novita Risfidian Mohadi Rizal Syarief Rizal Syarief Rizal Syarief Setiawan Yusuf Setiawan Yusuf Setiawaty Yusuf Sofia Sandi Sukmawati Sukmawati Susilawati Susilawati Syaflina Lamin Syafrina Lamin, Syafrina Syndi N.K Tridayona Tridayona Trimulyadi, Gatot Wiwin Wiwin Yusup Nur Khakim, Mokhamad