Article Per Year (5 Year)
p-Index From 2020 - 2025
1.607
P-Index
This Author published in this journals
All Journal Jurnal Ilmu Pertanian Indonesia Jurnal Teknologi Dan Industri Pangan Jurnal Sain Veteriner Indonesian Journal of Tropical and Infectious Disease Indonesian Journal of Biotechnology UNEJ e-Proceeding SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Biosaintifika: Journal of Biology & Biology Education Jurnal Pengabdian Masyarakat Kesehatan Journal of Aquaculture and Fish Health Indian Journal of Forensic Medicine & Toxicology Berkala Penelitian Hayati Exact Paper In Compilation (EPIC) Jurnal Kedokteran Hewan Journal of Fisheries & Marine
Win Darmanto
Departement Of Biology, Faculty Of Science And Technology, Airlangga University, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

Published : 30 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 30 Documents
Search

 1   2   3 
PROFIL DISTRIBUSI INOS DAN KADAR NO PANKREAS TIKUS DIABETES MELITUS HASIL INDUKSI MLD-STZ PASCA PEMBERIAN EKSTRAK ETANOL TEMUGIRING (Curcuma heyneana) Betti Lukiati; Aulanni’am a; Win Darmanto
Jurnal Kedokteran Hewan Vol 6, No 2 (2012): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (393.548 KB) | DOI: 10.21157/j.ked.hewan.v6i2.343

Abstract

Penelitian ini bertujuan menguji pengaruh ekstrak etanol temugiring terhadap distribusi inducible nitric oxide synthase (iNOS) dan kadar nitrogen oksida (NO) pada pankreas tikus diabetes hasil induksi multiple low dose-streptozotocin (MLD-STZ). Tiga macam dosis ekstrak etanol temugiring, yaitu 36, 72, dan 108 mg/kg bobot badan diberikan secara oral untuk terapi tikus diabetes hasil induksi MLD-STZ. Data distribusi iNOS dan kadar NO dianalisis dengan analisis varians jalur tunggal yang dilanjutkan dengan uji Duncan (α=0,05). Hasil analisis menunjukkan bahwa ekstrak etanol temugiring berpengaruh sangat nyata (P0,01) terhadap penurunan distribusi iNOS dan kadar NO pada pankreas tikus diabetes hasil induksi MLD-STZ. Dosis 72 mg/kg bobot badan ekstrak etanol temugiring merupakan dosis optimal untuk terapi tikus diabetes hasil induksi MLD-STZ. Disimpulkan bahwa ekstrak etanol temugiring dapat menurunkan distribusi iNOS dan kadar NO pankreas tikus penderita diabetes melitus.
APLIKASI BERBASIS ANDROID DALAM PEMETAAN DAN IDENTIFIKASI KONTAK PASIEN TB PARU DI KABUPATEN JOMBANG Win Darmanto; Sri Puji Astuti Wahyuningsih; Suhendra Agung Wibowo
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 7, No 2 (2023): June
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v7i2.15203

Abstract

ABSTRAKTuberkulosis masih menjadi permasalahan yang belum bisa teratasi bagi seluruh dunia. Banyak upaya yang telah dilakukan dalam penanganan dan belum mendapatkan hasil yang diharapkan. Salah satu penyebab kesulitan dalam penanganan tuberkulosis paru adalah karena pasien tersebar di wilayah yang luas pada saat menjalani pengobatan dan belum terpetakan. Melalui bantuan kader kesehatan penulis mencoba untuk memetakannya. Metode pengabdian masyarakat yang digunakan adalah berupa pendidikan dan pelatihan dalam menggunakan aplikasi berbasis android dalam pemetaan dan identifikasi kontak pasien TB Paru di kabupaten Jombang melalui kerjasama dengan TB Care Yayasan Bhanu Yasa Sejahtera (YABHYSA) kabupaten Jombang dan diikuti oleh 40 orang kader pendeteksi dan pengendali TB dibawah naungan TB Care YABHYSA Jombang. Kegiatan diawali dengan penyamaan persepsi pada tim pengabdian masyarakat, kemudian kader sebagai sasaran dikumpulkan dalam satu ruangan untuk menerima penjelasan tentang aplikasi sekaligus mempraktekkan bagaimana cara menggunakannya. Hasil pelatihan menunjukkan nilai post test 100% responden lebih baik daripada pre test. Aplikasi diserahkan kepada kader untuk dapat digunakan dalam pemetaan pasien TB Paru. Berdasarkan hasil post test dapat disimpulkan bahwa kader telah mengerti dan memahami cara penggunaan aplikasi sehingga siap untuk memetakan pasien TB Paru di Kabupaten Jombang. Kata kunci: pencegahan TB; aplikasi, pemetaan. ABSTRACTTuberculosis is still an unresolved problem for the whole world. Many efforts have been made in handling and have not received the expected results. One of the causes of difficulties in treating pulmonary tuberculosis is because patients are spread over a large area at the time of treatment and have not been mapped. Through the help of health cadres the author tries to map it. The community service method used is in the form of education and training in using an android-based application in mapping and identifying contacts of pulmonary TB patients in Jombang district through collaboration with the Bhanu Yasa Sejahtera Foundation (YABHYSA) Jombang district TB Care and attended by 40 TB detection and control cadres under the auspices of TB Care YABHYSA Jombang. The activity began with the equalization of perceptions on the community service team, then the cadres as targets were gathered in one room to receive an explanation about the application as well as practice how to use it. The results of the training showed that the post test scores of 100% of the respondents were better than the pre test. Applications are submitted to cadres to be used in mapping pulmonary TB patients. Based on the results of the post test, it can be concluded that the cadres understand and understand how to use the application so they are ready to map pulmonary TB patients in Jombang Regency. Keywords : TB prevention; application; mapping
PROFIL DISTRIBUSI INOS DAN KADAR NO PANKREAS TIKUS DIABETES MELITUS HASIL INDUKSI MLD-STZ PASCA PEMBERIAN EKSTRAK ETANOL TEMUGIRING (Curcuma heyneana) Betti Lukiati; Aulanni’am a; Win Darmanto
Jurnal Kedokteran Hewan Vol 6, No 2 (2012): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v6i2.343

Abstract

Penelitian ini bertujuan menguji pengaruh ekstrak etanol temugiring terhadap distribusi inducible nitric oxide synthase (iNOS) dan kadar nitrogen oksida (NO) pada pankreas tikus diabetes hasil induksi multiple low dose-streptozotocin (MLD-STZ). Tiga macam dosis ekstrak etanol temugiring, yaitu 36, 72, dan 108 mg/kg bobot badan diberikan secara oral untuk terapi tikus diabetes hasil induksi MLD-STZ. Data distribusi iNOS dan kadar NO dianalisis dengan analisis varians jalur tunggal yang dilanjutkan dengan uji Duncan (α=0,05). Hasil analisis menunjukkan bahwa ekstrak etanol temugiring berpengaruh sangat nyata (P0,01) terhadap penurunan distribusi iNOS dan kadar NO pada pankreas tikus diabetes hasil induksi MLD-STZ. Dosis 72 mg/kg bobot badan ekstrak etanol temugiring merupakan dosis optimal untuk terapi tikus diabetes hasil induksi MLD-STZ. Disimpulkan bahwa ekstrak etanol temugiring dapat menurunkan distribusi iNOS dan kadar NO pankreas tikus penderita diabetes melitus.
Okra Polysaccharides Improves Spleen Weight and B-Lymphocytes Proliferation in Mice Infected by Staphylococcus aureus Sri Puji Astuti Wahyuningsih; Manikya Pramudya; Intan Permata Putri; Nadyatul Ilma Indah Savira; Dwi Winarni; Listijani Suhargo; Win Darmanto
Biosaintifika: Journal of Biology & Biology Education Vol 9, No 3 (2017): December 2017
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v9i3.11284

Abstract

Okra (Abelmoschus esculentus) is reported to have various biological functions such as antioxidant, anticancer and anti-inflammation. However, only few studies have been reported immunomodulatory activities of okra to prevent disease caused by bacteria infection. In this study, the immunomodulatory activities of polysaccharides from okra pods were investigated further through the spleen weight and B-lymphocytes proliferation in mice infected by Staphylococcus aureus. Okra polysaccharides were obtained by water extraction and ethanol precipitation. Okra polysaccharides with doses of 25, 50, 75, and 100 mg/kg BW were orally administrated to mice with or without Staphylococcus aureus infection. Spleen weight was evaluated in both treatment group and control group. B-lymphocytes proliferation was evaluated by MTT assay using LPS induction. Results showed that okra polysaccharide at the doses of 50, 75, and 100 mg/kg increased spleen weight (p 0.05) significantly. While at the dose of 75 and 100 mg/kg, it increased the B-lymphocytes proliferation (p 0.05) significantly. There is positive correlation between the spleen weight and B-lymphocytes proliferation by 73.3%. These result reveal that okra polysaccharide could improve the immune response and be utilized as a novel candidate of neutraceutical.
Effect on Polysaccharide Krestin from Coriolus versicolor Extract on Phagocytic Activity and Capacity of Mus musculus Exposed by Pseudomonas aeruginosa Sri Puji Astuti Wahyuningsih; Nadyatul Ilma Indah Savira; Win Darmanto
Biosaintifika: Journal of Biology & Biology Education Vol 8, No 3 (2016): December 2016
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v8i3.6957

Abstract

Pseudomonas aeruginosa is an opportunistic bacterium that causes infections in human. The wall cell of its bacteria contains lipopolysaccharide as virulency factors to protect it from human immunity. Lipopolysaccharide can inhibit phagocytosis in the body. Polysaccharide krestin (PSK) from Coriolus versicolor extract contains β-glucan that can increase phagocytic activity and capacity. This research aimed to identify the effect on polysaccharide krestin from C. versicolor extract on phagocytic activity and capacity of mice exposed by P. aeruginosa. The design of this research was experimental design. There were six treatment groups. The phagocytic activity and capacity were counted on slide smears of mice peritoneal fluid. The data was analyzed by using one way ANOVA. The results of the phagocytic activity and capacity showed that PSK was added before exposure (P1) or after exposure (P2) or before-after exposure (P3) had potential to increase phagocytic activity and capacity.  The conclusion of the research was that adding polysaccharide krestin either before exposure or after exposure or both of them could increase phagocytic activity and capacity. The benefits of this research to development of science are expected to reduce human infection and to utilize natural ingredients as immunomodulator.How to CiteWahyuningsih, S. P. A., Savira, N. I. I, Darmanto, W. (2016). Effect on Polysaccharide Krestin from Coriolus versicolor Extract on Phagocytic Activity and Capacity of Mus musculus Exposed by Pseudomonas aeruginosa. Biosaintifika: Journal of Biology Biology Education, 8(3), 308-313. 
Kejadian Kelainan Vertebra Ikan Nila (Oreochromis niloticus) pada Media Penetasan Salinitas yang Berbeda [Vertebrae Malformation Tilapia Fish (Oreochromis niloticus) on Different Media Hatching Saline] Lailatul Lutfiyah; Rr Juni Triastuti; Endang Dewi Masithah; Win Darmanto
Jurnal Ilmiah Perikanan dan Kelautan Vol. 6 No. 2 (2014): JURNAL ILMIAH PERIKANAN DAN KELAUTAN
Publisher : Faculty of Fisheries and Marine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jipk.v6i2.11312

Abstract

Abstract Tilapia fish belonged to the euryhaline fish, which has wide range tolerance in salinity (freshwater euryhaline fish has salinity tolerance >8 ppt). Incidence of fish skeletal abnormalities could be the response of the environment influence such as salinity, temperature and hypoxia. This research uses five treatments : 0,5 10, 15, 20 ppt. The results showed that the highest abnormalities found on the treatment of 15 ppt and 20 ppt, while the lowest for the treatment of abnormalities of 10 ppt. The best result to be used in the brackish nila aquaculture is 10-15 ppt in salinity.
Improving Case Detection Rate( Cdr) By “Simatb” As Tuberculosis Screening Application Of High Risk Groups In Wonosalam: Upaya Peningkatan Case Detection Rate (Cdr) Tuberkulosis Di Kabupaten Jombang Melalui “Simatb” Sebagai Aplikasi Skrining Tuberkulosis Pada Faktor Beresiko Di Wonosalam Jombang farach; darmanto, Win; Pujiastuti Wahyuningsih , Sri; Puspita Sari, Evi; Susanto, awaluddin
Jurnal Pengabdian Masyarakat Kesehatan Vol. 9 No. 2 (2023): JPM | September 2023
Publisher : UPPM - STIKES Pemkab Jombang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33023/jpm.v9i2.1762

Abstract

Capaian Case detection rate (CDR) TBC di Kabupaten Jombang Tahun 2021 belum mencapai target yang diinginkan. Sistem rujukan belum optimal, kurangnya keikutsertaan masyarakat dalam menemukan penderita, masyarakat memandang penyakit TBC dapat menggambarkan stigma negative dan mengakibatkan efek rasa malu dan terisolir bagi penderitanya. Kegiatan pengabdian masyarakat yang bertujuan untuk mengetahui kasus baru TB fakto resiko yang berada di Wonosalam sebagai upaya peningkatan CDR. Metode pelaksanaan kegiatan dilakukan (1) Persiapan meliputi penyuluhan penularan dan bahaya penyakit TBC (2) Pelaksanaan meliputi pemeriksaan kesehatan pada semua factor beresiko dan skrining untuk penemuan kasus tuberculosis melalui investigasi kontak dengan sasarannya adalah orang yang memiliki resiko. Hasil kegiatan menunjukkan 100% jumlah sputum beresiko tidak mengandung mikobakteri tuberculosis dan penggunaan aplikasi simaTB sangat berguna dalam kegiatan skrining TB selanjutnya. Kesimpulan yang didapatkan adalah Jumlah sputum factor beresiko di Wonosalam sebanyak 36 sampel dan menghasilkan negative mikobakterium Tuberkulosis.Aplikasi simaTB dapat digunakan sebagai upaya peningkatan case detection rate (CDR) tuberkulosis di kabupaten jombang melalui “simatb” sebagai aplikasi skrining tuberkulosis pada faktor beresiko di wonosalam jombang
THE EFFECTIVENESS OF HERBAL MOSQUITO COILS "MORIZENA” AGAINST Aedes Aegypti DEATH Susilowati, Rina Priastini; Darmanto, Win; Aminah, Nanik Siti
Indonesian Journal of Tropical and Infectious Disease Vol. 7 No. 2 (2018)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (625.03 KB) | DOI: 10.20473/ijtid.v7i2.7324

Abstract

It has been successfully found new herbal mosquito coils called "Morizena” made from Passiflora foetida leaf extract (40%), Chrysantemum cinerariaefolium flowers seed extract (40%), essential oils of  leaves-stems of Cymbopogon nardus (20%). The herbal mosquito coils are more effective to kill Aedes aegypti compared to commercial synthetic mosquito coils made from Transfluthrin. Treatment of exposure to herbal mosquito coils "Morizena” on Aedes aegypti for 8 hours/day with concentration 500 ppm (P1), 1000 ppm (P2), 2000 ppm (P3), 3000 ppm (P4), 4000 ppm (P5) and treatment of exposure to synthetic mosquito coils Transfluthrin 2500 ppm (K1) as a positive control, and without treatment of exposure to mosquito coils (K0) as a negative control. Experimental animals used were adult Ae. aegypti mosquito with 25 mosquitoes in each treatment. Experimental design used is one-way Anova test with linear regression to calculate its LC50 and LC90. The results of test to herbal mosquito coils "Morizena” given for 8 hours/day obtained mortality of Ae. aegypti by 92% to a concentration of 3000 ppm (P4) and 100% to a concentration of 4000 ppm (P5) and 100% for test to synthetic mosquito coils transfluthrin 2500 ppm (K1). Ae. aegypti LC50 and LC90 value for treatment of exposure to herbal mosquito coils "Morizena” are 999 ppm and 2977 ppm. Treatment of herbal mosquito coils "Morizena” with graded doses up to 4000 ppm and synthetic mosquito coils Transfluthrin 2500 ppm causing an increase in the enzyme acetylcholinesterase activity of Ae. aegypti. The conclusion is based on the Ae. aegypti  LC90 value is 2977 ppm, which means the effective dose of herbal mosquito coils "Morizena” to kill Ae. aegypti is 2977 ppm.
Bioconversion of Microalga Chlorella sp. as an Alternative Energy for Biofuel in Fishery Waste Media Rochmatika, Endah; Mubarak, Ahmad Shofy; Darmanto, Win
Jurnal Ilmu Pertanian Indonesia Vol. 30 No. 2 (2025): Jurnal Ilmu Pertanian Indonesia
Publisher : Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18343/jipi.30.2.416

Abstract

Carbon dioxide emissions from burning fuel oil have been increasing, resulting in increasingly severe climate change. The use of microalgae as raw materials for biofuel production is an environmentally friendly alternative. Microalgae Chlorella sp. can be sustainably converted into alternative biofuels. Fishery liquid waste, such as that resulting from fish farming and fish processing, can be used as a nutrient medium for microalgae. This study aimed to analyze biomass production from Chlorella sp. using fishery waste in an algae reactor. The working principle of fisheries wastewater processing is related to microalgae in the reactor. The surface of the media forms a biological layer that breaks down organic compounds in the air, thereby reducing the organic content. The compounds resulting from metabolic processes are in the form of solids and gases. The results show that the bioethanol produced from the thermostat Chlorella sp. with fishery waste media can produce 20,000 L/ha. Microalgae contain approximately 20-50% dry weight of carbohydrates, which can be converted into bioethanol. Chlorella sp. can reduce chemical oxygen demand and ammonia by up to 70% by converting carbon dioxide into carbohydrates, fats, and proteins. The application of bioconversion to all companies in the fisheries sector will provide benefits and help the government reduce fossil fuel subsidies. Keywords: bioconversion, biofuel, fisheries, microalgae, waste
Potensi Ekstrak Ganoderma applanatum Terhadap Kadar MDA dan Bax pada Mencit (Mus musculus) yang Terinduksi Diethylnitrosamine Rahayu, Siti; Darmanto, Win; Wahyuningsih, Sri Puji Astuti
Exact Papers in Compilation (EPiC) Vol. 7 No. 2 (2025): Mei 2025
Publisher : Lembaga Penelitian Pengabdian Masyarakat Universitas KH. A. Wahab Hasbullah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32764/epic.v7i2.1514

Abstract

Polisakarida Ganoderma applanatum memiliki sifat antioksidan sebagai respon biologis yang kuat untuk terapi kanker. Penelitian ini menguji potensi ekstrak polisakarida G. applanatum terhadap kadar MDA dan Bax pada tikus (Mus musculus) yang diinduksi DEN. Tikus betina galur DDY dibagi secara acak menjadi 4 kelompok (n=6). DEN diberikan secara intraperitoneal dua kali seminggu, kemudian doxorubicin sebagai kontrol positif dan ekstrak polisakarida sebagai perlakuan selama satu bulan secara oral. Metode penelitian dilakukan dengan membandingkan KN yang diberi air; K- yang diberi DEN 100 mg/kg BB; K+ yang diberi DEN 100 mg/kg BB dan doksorubisin 10 mg/kg BB; dan P yang diberi DEN 100 mg/kg BB dan ekstrak polisakarida G. applanatum 150 mg/kg BB. Dari analisis statistik uji ANOVA yang dilanjutkan dengan uji Duncan, diperoleh bahwa pemberian ekstrak polisakarida G. applanatum dibandingkan dengan K- tidak menunjukkan perbedaan bermakna kadar MDA dan Bax. Data hasil percobaan sebagai berikut: KN menunjukkan kadar MDA sebesar 1,62±0,28 nmol/mL dan Bax 4,41±2,14 ng/mL. Kadar MDA K- sebesar 1,58±0,11 nmol/m dan Bax 3,91±1,84 ng/mL. Kadar MDA K+ sebesar 1,75±0,21 nmol/mL dan Bax 4,30±1,61 ng/mL. Kadar MDA P sebesar 1,74±0,29 nmol/mL dan Bax 2,28±1,27 ng/mL.
Co-Authors A. Shofy Mubarak Agoes Soegianto Agus Abadi Agus Heri Setyo Wahyudi Alifah Hayati Andita Ayu Mandasari Aulanni'am, Aulanni'am Bambang Poernomo Betti Lukiati Binti Yunaida Djoko Agus P. Dwi Winarni Eko Prihiyantoro Eko Prihiyantoro Endah Rochmatika Endang Dewi Masithah farach Harianto Notopuro I.B. Rai Pidada Intan Permata Putri Intan Permata Putri Is Yuniar Juliana Christyaningsih Lailatul Lutfiyah, Lailatul Listijani Suhargo, Listijani Mammed Sagi Manikya Pramudya Mochammad Amin Alamsjah Mufasirin Mutiarawati, Diah Titik Nadyatul Ilma Indah Savira Nanik Siti Aminah Natalia Tri Astuti Nunuk Dyah Retno Lastuti Nurmalasari Darsono Nurmalasari Darsono P Kumaladewi Pieter Kakisina Pujiastuti Wahyuningsih , Sri Puspita Sari, Evi Putri Andreyna Saragi Ramadhana Ramadhana Retnosari Apriasti Ria Harmonis Rochmatika, Endah Rr. Juni Triastuti Samekto Wibowo Sapto Andriyono Siti Rahayu Sri Kadarsih Soedjono Sri Puji Astuti Sri Puji Astuti Wahyuningsih, Sri Puji Astuti Sugiharto Suhendra Agung Wibowo Sukardiman Susanto, Awaluddin Susilowati, Rina Priastini Suvia Widyaningrum Tri Dewanti W. Victorin Mega Putri Widhi Dyah Sawitri YULIA IRNIDAYANTI Yuni Kilawati