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Aktivitas Antibakteri Buah Laban (Vitex pubescens V) yang Tumbuh di Dalam dan di Luar Kawasan Geothermal Ie Seum Aceh Besar terhadap Propionibacterium acnes dan Staphylococcus epidermidis: Antibacterial Activity Of Laban Fruit (Vitex pubescens V) Which Grows In And Outside Geothermal Areas Ie Seum Aceh Besar Against Propionibacterium acnes AND Staphylococcus epidermidis Rasidah; Jeni Windiyasari; Vonna Aulianshah; Munira; Noni Zakiah; Rini Handayani
Indonesian Journal of Pharmacy and Natural Product Vol. 7 No. 01 (2024): Indonesian Journal of Pharmacy and Natural Product
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/ijpnp.v7i01.2619

Abstract

Acne can be caused by clogged skin pores causing red spots, inflammation and infection. Infections of the skin can be caused by the bacteria Propionibacterium acnes and Staphylococcus epidermidis. One plant that has antibacterial potential is laban. Laban plants usually live freely scattered in terrestrial and hilly areas, one of which is in the Ie Seum area in Aceh Besar Regency which is a geothermal area in Aceh. The Ie Seum area has a higher soil pH and temperature compared to other areas (non-geothermal). This study was conducted to determine the difference in antibacterial activity between laban fruit extract (Vitex pubescens V) growing inside and outside the geothermal area of Ie Seum Aceh Besar in inhibiting the growth of Propionibacterium acnes and Staphylococcus epidermidis using disc diffusion method. Microbiological test results obtained the diameter of the inhibitory zone against Propionibacterium acnes and Staphylococcus epidermidis  respectively geothermal laban fruit extract (14.33±1.21 mm and 12.66±1.69 mm) and laban fruit extract outside geothermal (14.83±1.69 mm and 11.41±2.28 mm) and chloramphenicol (19.66±1.88 mm and 22.00±2.50 mm). Anova test results are known to be very influential laban fruit extract (P = 0.000) on the growth of Propionibacterium acnes and Staphylococcus epidermidis. Duncan's further test results found that laban fruit extracts inside and outside the geothermal region had no real difference in inhibiting the growth of Propionibacterium acnes and Staphylococcus epidermidis. The difference in growing place did not provide a difference in antibacterial activity from laban fruit extract (P<0.005).   ABSTRAK Jerawat dapat disebabkan karena tersumbatnya pori-pori kulit sehingga menimbulkan bintik merah, peradangan dan infeksi. Infeksi pada kulit dapat disebabkan oleh bakteri Propionibacterium acnes dan Staphylococcus epidermidis. Salah satu tanaman yang memiliki potensi sebagai antibakteri adalah laban. Tanaman laban biasanya hidup tersebar secara bebas di daerah teresterial dan perbukitan, salah satunya pada kawasan Ie Seum di Kabupaten Aceh Besar yang merupakan daerah geothermal di Aceh. Kawasan Ie Seum memiliki pH tanah dan suhu yang lebih tinggi dibandingkan dengan daerah lainnya (non geothermal). Penelitian ini dilakukan untuk mengetahui perbedaan aktivitas antibakteri antara ekstrak buah laban (Vitex pubescens V) yang tumbuh di dalam dan di luar kawasan geothermal Ie Seum Aceh Besar dalam menghambat pertumbuhan Propionibacterium acnes dan Staphylococcus epidermidis menggunakan metode difusi cakram. Hasil uji mikrobiologi diperoleh diameter zona hambat terhadap Propionibacterium acnes dan Staphylococcus epidermidis berturut-turut ekstrak buah laban geothermal (14,33±1,21 mm dan 12,66±1,69 mm); ekstrak buah laban di luar geothermal (14,83±1,69 mm dan 11,41±2,28 mm) serta kloramfenikol(19,66±1,88 mm dan 22,00±2,50 mm). Hasil uji Anova diketahui ekstrak buah laban sangat berpengaruh (P=0,000) terhadap pertumbuhan Propionibacterium acnes dan Staphylococcus epidermidis. Hasil uji lanjut Duncan diperoleh bahwa ekstrak buah laban di dalam dan di luar kawasan geothermal tidak memiliki perbedaan nyata dalam menghambat pertumbuhan Propionibacterium acnes dan Staphylococcus epidermidis. Perbedaan tempat tumbuh tidak memberikan perbedaan aktivitas antibakteri dari ekstrak buah laban (P<0,005).
Pemberdayaan Mahasiswa Melalui Pemanfaatan Media Youtube Dalam Peningkatan Ketrampilan Wirausahaan Salfiyadi, Teuku; Abdurrahman; Rasidah; Elfi Zahara; Safwan
JEUMPA: Jurnal Pengabdian Kepada Masyarakat Vol 3 No 2 (2024): EDISI II
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/jeumpa.v3i2.784

Abstract

Para mahasiswa dalam menghadapi tantangan masa modern diperlukan kentrampilan dalam pengelolaan media menjadi sebuah keunggulan. Dalam menghadapi permasalahan di kalangan luar yang belum optimal serta lemahnya rapuhnya kelembagaan mahasiswa yang belum mampu memberikan kontribusi . Oleh karena itu penting untuk melakukan pemberdayaan mahasiswa melalui pelatihan penggunaan media social youtube untuk pemasaran dalam Menyusun konten creator yang menarik. Tujuan program ini adalah mendorong pengembangan usaha bagi mahasiswa yang lebih kreatif. Kegiatan ini dilaksanakan melalui metode survei partisipatif, observasi, ceramah, diskusi, dan praktik langsung, dengan melibatkan beberapa 11 orang mitra yang berasal dari perwakilan kelompok tani. Hasil pelaksanaan program memperlihatkan keseriusan dan antusias peserta dalam setiap sesi pelatihan. Beberapa hal teknis yang dapat dipahami oleh mitra program antara lain; manajemen usaha creator mahasiswa berbasis kewirausahaan sosial, pemanfaatan social media marketing, dengan peningkatan pemahaman sebesar 27 poin (68%) dibanding sebelum pelatihan, serta kesepakatan pembentukan lembaga mahasiswa sebagai sentra pengembangan hasil karya mahaswa.
PENGARUH WAKTU PEMETIKAN TERHADAP KADAR FLAVONOID TOTAL DAN AKTIVITAS ANTIOKSIDAN ESKTRAK DAUN KELOR (Moringa oleifera) Aulianshah, vonna; Rasidah, Rasidah; Handayani, Rini
JURNAL ILMIAH FARMASI SIMPLISIA Vol. 4 No. 2 (2024): Desember 2024
Publisher : Jurusan Farmasi, Politeknik Kesehatan Kementerian Kesehatan Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/jifs.v4i2.708

Abstract

Moringa is a plant that is believed to have antioxidant activity that is able to provide cell defense against reactive oxygen species that cause cell damage. This activity is likely mediated by the high total flavonoid content of Moringa leaves, but the chemical content of the plant is highly dependent on several factors, one of which is the time of picking or picking. The purpose of this study is to determine the effect of picking time on the total level of flavonoids and antioxidant activity of Moringa leaf extract (Moringa oleifera). The study was experimental by using two bound variables, namely total flavonoid levels and antioxidant activity from moringa leaf extract collected with different picking, namely at 6-7 a.m (EEDK1), 12-13 p.m (EEDK2) and 17-18 p.m (EEDK3) on the same day. Moringa leaf extract is made using a repetitive maceration method with a 70% ethanol solvent. The measurement of total flavonoid levels was carried out by spectrophotometry method with a concentration of 10,000 ppm and used quercetin as the benchmark standard. Antioxidant activity was determined through the DPPH method with extract concentrations of 20, 40, 60, 80 and 100 ppm. The measurement results were analyzed for the percentage of inhibition and the IC50 (inhibitory concentration) value was calculated using the linear regression curve equation. Vitamin C was used as a comparison The measurement results of each test sample showed a significant difference in the percentage of inhibition and IC50 value, where EEDK1 was the most active and categorized as very strong with a value of 45.08 ppm. With these significant differences, it can be concluded that the picking time affects the total flavonoid levels and anti-oxidation activity of Moringa leaves
Asesmen Spektrofotometri Flavonoid Dalam Peperomia Pellucida L. Kunth: Studi Perbandingan Polaritas Pelarut Safrina; Riski Andalia; Rasidah; Nanda Arulia
Journal of Science and Health Darussalam Vol. 5 No. 1 (2025): Jurnal Sains dan Kesehatan Darussalam
Publisher : Akademi Analis Farmasi dan Makanan Banda Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56690/jskd.v5i1.159

Abstract

Penelitian ini bertujuan untuk mengeksplorasi kandungan flavonoid pada ekstrak Peperomia pellucida L. Kunth berdasarkan perbedaan polaritas pelarut. Penentuan kadar flavonoid dilakukan menggunakan metode spektrofotometri UV-Vis dengan kuersetin sebagai standar. Ekstraksi sampel dilakukan menggunakan metode maserasi, di mana ekstrak etil asetat (EAE) menghasilkan ekstrak kental sebanyak 13,092 gram dengan rendemen 26,184%, sedangkan ekstrak etanol (EtE) menghasilkan ekstrak cair sebanyak 88,84 gram dengan rendemen 177,68%. Pengukuran dilakukan pada panjang gelombang 431 nm. Hasil penelitian menunjukkan bahwa ekstrak etanol 70% memiliki kadar flavonoid yang lebih tinggi dibandingkan dengan ekstrak etil asetat, yang dikonfirmasi melalui analisis statistik menggunakan ANOVA (p < 0,05). Analisis regresi juga menunjukkan bahwa model EtE memiliki distribusi residual yang lebih baik dibandingkan EAE, menandakan hubungan prediktif yang lebih kuat. Pada model regresi EAE diperoleh nilai intercept sebesar 203,8095 (p = 0,02002) dan slope sebesar 0,07143 (p = 0,33333), yang menunjukkan bahwa kontribusi variabel independen tidak signifikan secara statistik. Sebaliknya, model EtE menghasilkan nilai intercept sebesar 233,571 dengan slope nol, yang semakin menegaskan bahwa etanol lebih efektif dalam mengekstraksi flavonoid. Secara keseluruhan, hasil penelitian ini menegaskan pentingnya pemilihan pelarut dalam proses ekstraksi flavonoid dan menunjukkan potensi Peperomia pellucida sebagai sumber antioksidan alami, sehingga dapat dikembangkan lebih lanjut dalam terapi berbasis herbal.
Pemberdayaan kader dalam edukasi dampak merokok terhadap kesehatan gigi dan mulut pada penderita diabetes Nuraskin, Cut Aja; Rasidah, Rasidah; Reca, Reca; Salfiyadi, Teuku
Jurnal PADE: Pengabdian & Edukasi Vol 7, No 2 (2025): Oktober
Publisher : Politeknik Kesehatan Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/pade.v7i2.2726

Abstract

The community service activity entitled “Empowering Health Cadres in Disseminating the Impact of Smoking on Oral Health among Diabetes Mellitus Patients in Darul Imarah Subdistrict, Aceh Besar” was successfully carried out. The objective was to increase community awareness regarding the causes, symptoms, and complications of diabetes mellitus; the impact of smoking on oral health in diabetes patients; the prevention and treatment of periodontal disease; and efforts to reduce the prevalence of diabetes mellitus. The method used was education and counseling involving 40 participants, including health cadres, PKK members, youth groups, and diabetes patients.Pre-test results indicated low levels of knowledge: 55% on diabetes mellitus, 50% on the impact of smoking, 48% on periodontal disease prevention, and 52% on efforts to reduce diabetes prevalence. After the intervention, post-test results showed improvement, with knowledge increasing to 85% on diabetes mellitus, 82% on smoking impact, 80% on periodontal disease prevention, and 83% on diabetes prevention efforts. Overall, the average increase reached 31,25%. Based on the distribution of knowledge improvement, 65% of participants experienced a high increase (>30%), 30% moderate (15–30%), and 5% low (<15%). It can be concluded, Education and counseling significantly improved participants’ knowledge, with an average increase of 31,25%. The majority (65%) achieved a high level of improvement. Further guidance is recommended for participants with low improvement.
Pencegahan stunting melalui edukasi gizi seimbang dan pemanfaatan pekarangan untuk kebun gizi dan toga di Desa Bayu, Kecamatan Darul Imarah, Aceh Besar Rasidah, Rasidah; Nuraskin, Cut Aja; Al Rahmad, Agus Hendra; Reca, Reca; Salfiyadi, Teuku; Mardiah, Ainun; Usrina, Nora
Jurnal PADE: Pengabdian & Edukasi Vol 7, No 2 (2025): Oktober
Publisher : Politeknik Kesehatan Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/pade.v7i2.2727

Abstract

Stunting is a chronic nutritional problem that affects child growth and has long-term impacts on quality of life. This community service activity aimed to reduce stunting rates and empower communities in addressing family nutritional deficiencies. The methods used included counseling, training, and community group mentoring. The results showed an increase in mothers’ understanding of stunting by 42%, an improvement in the number of families applying balanced nutrition from 56% (pre-test) to 86% (post-test), as well as the establishment of 52% new nutrition and medicinal plant gardens (TOGA) with active participation from 84% of participants. This activity demonstrates that educational and participatory community-based approaches are effective in raising awareness and fostering community independence in stunting prevention.
SPECTROSCOPIC ANALYSIS OF A COMPOUND ISOLATED FROM THE ETHYL ACETATE FRACTION OF CALOPHYLLUM MACROPHYLLUM SCHEFF AND TOXICITY TESTS USING THE BSLT METHOD AGAINST ARTEMIA SALINA LEACH LARVAE Zakiah, Noni; Munira, M; Handayani, Rini; Rasidah, R; Frengki, F
Jurnal Kedokteran Hewan Vol 16, No 4 (2022): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v16i4.23398

Abstract

The Calophyllum genus has been reported to be rich in bioactive compounds that have medicinal properties. The author will also report the results of the isolation of compounds obtained from the ethyl acetate fraction of the bark of the plant C. macrophyllum Scheff, a type of Calophyllum found in Mount Kerinci, Jambi province. This paper will analyze the spectroscopic data of these compounds which include UV, IR, GC-MS, 1HNMR and 13CNMR spectra which are amplified by HMQC and HMBC spectra. The first step in bioactivity testing is the toxicity test using the BSLT (Brine Shrimp Lethality Test) method using Artemia Salina Leach shrimp larvae. The results of the spectroscopic analysis obtained the chemical formula as a derivative of fatty acid methyl ester (methyl-octadec-14 enoic), in the form of a yellow liquid with a boiling point of 173-175C. The results of the initial screening for bioactivity through the toxicity test of the BSLT method on Artemia salina Leach shrimp larvae obtained an LC50 value of 141.2 g/mL. This compound still has the potential to have certain bioactivity
Acute Antihyperglycemic Activity of Kepok Banana Blossom (Musa paradisiaca L.) Extract in Mice Rini Handayani; Rasidah; Munira; Noni Zakiah; Agus Hendra Al Rahmad
Jurnal teknologi Kesehatan Borneo Vol 7 No 1 (2026): Jurnal teknologi Kesehatan Borneo
Publisher : POLTEKKES KEMENKES PONTIANAK

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jtkb.v7i1.476

Abstract

Banana inflorescence contains phytochemicals that may modulate postprandial glucose, but evidence for freshly prepared Kepok banana blossom is limited. This exploratory animal study evaluated the acute antihyperglycemic activity of 40%, 50%, and 60% fresh Kepok banana blossom (Musa paradisiaca L.) preparations using an oral glucose tolerance test. Twenty-five male mice were randomly allocated to distilled-water control, metformin control, or three extract groups (n = 5/group). Following fasting and oral glucose loading, blood glucose was measured before and after loading and at 30, 60, and 120 minutes after intervention. Qualitative screening detected alkaloids, saponins, flavonoids, phenolics, and tannins. At 120 minutes, mean glucose levels were 169.0 mg/dL in the negative control, 123.6 mg/dL with metformin, and 121.0, 136.6, and 125.0 mg/dL with the 40%, 50%, and 60% preparations, respectively. Descriptive mean-curve AUC values were 23,457, 18,525, 19,308, 19,650, and 19,740 mg/dL·min. These results suggest that fresh Kepok banana blossom preparations attenuated the acute glucose excursion compared with distilled water. However, the small sample, qualitative-only phytochemistry, nonstandardized dosing, and absence of a chronic diabetes model preclude conclusions about equivalence among concentrations, mechanism, or antidiabetic efficacy
Pemberdayaan Kader Kesehatan Melalui Pelatihan Obat Kumur Daun Laban Untuk Mengurangi Gingivitis Pada Ibu Hamil Cut Aja Nuraskin; Abdurrahman; Reca; T Iskandar Faisal; Rasidah; Teuku Salfiyadi
JEUMPA: Jurnal Pengabdian Kepada Masyarakat Vol 5 No 2 (2026): EDISI II
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/jeumpa.v5i2.1520

Abstract

Salah satu bahan herbal yang potensial adalah ektrak daun laban yang dapat dijadikan bahan dasar obat kumur. Tujuan pengabdianmasyarakat ini antara lain, meningkatkan pengetahuan kader tentang gingivitis pada ibu hamil, peningkatan keterampilan kader dalam pembuatan obat kumur herbal, menurunkan risiko kelahiran bayi dengan berat badan lahir rendah (BBLR) dan kelahiran prematur, yang sering dikaitkan dengan kondisi gingivitis pada ibu hamil. Solusi yang ditawarkan untuk permasalahan tersebut antara lain, pelatihan masyarakat kelompok PKK dan ibu hamil tentang identifikasi dan edukasi tanda-tanda gingivitis pada ibu hamil dan teknik menjaga kesehatan gigi, melatih masyarakat teknik pembuatan obat kumur daun laban, mendistribusikan obat kumur pada ibu hamil dan mengajarkan cara penggunaan obat kumur kakao, edukasi pada ibu hamil pentingnya menjaga kesehatan gigi selama masa kehamilan, pemantauan hasil sebelum dan sesudah pengabdian masyarakat. Target luaran PPDS adalah, 1. peningkatan pengetahuan dan keterampilan kader kesehatan, 2. penurunan prevalensi gingivitis pada ibu hamil, 3. peningkatan kesehatan gigi ibu hamil, penggunaan obal kumur bahan lokal, 4. peningkatan kesadaran dan kesejahteraan masyarakat, terciptanya kolaraborasi antar sektor kesehatan dan dokumentasi. Target luaran kelembagaan adalah, artikel di sinta, media cetak, media elektronik, dan vidio kegiatan. Rencana kegiatan, FGD, survei, persiapan perijinan, persiapan bahan dan alat, persiapan kelompok PKK, pelatihan Kelompok PKK, edukasi pada ibu hamil, pelatihan pembuatan obat kumur dan distribusi obat kumur, monitoring dan evaluasi ibu hamil, kolaborasi denga tenaga kesehatan, penyusulan laporan dan publikasi.